keyword
https://read.qxmd.com/read/38536953/fetoscopic-laser-coagulation-for-twin-to-twin-transfusion-syndrome-a-comparison-of-flexible-1-0-1-2%C3%A2-mm-fetoscopes-with-curved-sheaths-of-2-7-3-3%C3%A2-mm-2-vs-2%C3%A2-mm-fetoscopic-lens-technique-with-sheaths-of-6-6-11-3%C3%A2-mm-2
#1
JOURNAL ARTICLE
Michael Tchirikov, Anja Zühlke, Natalia Schlabritz-Lutsevich, Michael Entezami, Gregor Seliger, Michael Bergner, Weijing Li, Angela Köninger, Andreas Wienke, Rustem Yusupbaev, Andreas D Ebert
OBJECTIVES: Fetoscopic laser coagulation of placental anastomoses is usually performed for a treatment of twin-to-twin transfusion syndrome (TTTS). A common complication of fetoscopic laser coagulation for TTTS is preterm preliminary rupture of fetal membranes (PPROM) aggravating the neonatal outcome significantly. However, use of an flexible 1 mm fetoscope with an curved sheath could reduce iatrogenic damage of the amniotic membrane and improve neonatal outcomes after laser treatment...
March 28, 2024: Journal of Perinatal Medicine
https://read.qxmd.com/read/38535563/lung-microbiota-and-ventilator-associated-pneumonia-in-the-neonatal-period
#2
REVIEW
Fermín García-Muñoz Rodrigo, Lourdes Urquía Martí, Marta Siguero Onrubia, Moreyba Borges Luján, Gloria Galán Henríquez, Desiderio Reyes Suárez
The lung microbiota is a complex community of microorganisms that colonize the respiratory tract of individuals from, or even before, birth. Although the lungs were traditionally believed to be sterile, recent research has shown that there is a diversity of bacterial species in the respiratory system. Knowledge about the lung microbiota in newborns and its relationship with bacterial infections is of vital importance to understand the pathogenesis of respiratory diseases in neonatal patients undergoing mechanical ventilation...
March 1, 2024: Pathogens
https://read.qxmd.com/read/38530963/impact-of-birth-weight-to-placental-weight-ratio-and-other-perinatal-risk-factors-on-left-ventricular-dimensions-in-newborns-a-prospective-cohort-analysis
#3
JOURNAL ARTICLE
Ashraf Gad, Dhafer Malouche, Manoj Chhabra, Danthanh Hoang, Debbie Suk, Nitin Ron, Beata Dygulska, Madhu B Gudavalli, Ali M Nadroo, Pramod Narula, Ibrahim Elmakaty
OBJECTIVES: To investigate the association between birth weight to placental weight (BW/PW) ratio, and echocardiographic left ventricle (LV) morphology at birth, while accounting for other relevant perinatal factors. METHODS: A prospective cohort study was conducted on neonates at NewYork-Presbyterian Brooklyn Methodist Hospital from 2014 to 2018, categorized by their BW/PW percentile. Missing data were imputed with principal component analysis. Chi-squared and one-way analysis of variance were used to compare BW/PW groups and the best regression model was selected using a genetic and backward stepwise algorithm...
March 27, 2024: Journal of Perinatal Medicine
https://read.qxmd.com/read/38525657/hospital-based-surveillance-of-children-with-cerebral-palsy-in-suriname-the-suriname-cerebral-palsy-register
#4
JOURNAL ARTICLE
Marlies H P Declerck, Israt Jahan, Neirude P A Lissone, Fenna Walhain, Ruby Chin A Fat, Marianne Fleurkens, Sarfaraz H J Muradin, Rhea Cruden, Els Ortibus, Nadia Badawi, Gulam Khandaker
AIM: To describe the aetiological risk factors, clinical characteristics, access to rehabilitation, and educational status of children with cerebral palsy (CP) in Suriname. METHOD: Hospital-based surveillance of children with CP aged younger than 18 years was conducted at the Academic Hospital Paramaribo, Suriname (known as the Suriname CP Register [SUR-CPR]). Data were collected on sociodemographic characteristics, aetiological risk factors, clinical characteristics, rehabilitation, and educational status...
March 25, 2024: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/38524952/maternal-and-neonatal-risk-factors-associated-with-perinatal-depression-a-prospective-cohort-study
#5
JOURNAL ARTICLE
Bharathi Rajendran, Syed Ummar Ibrahim, Sureshkumar Ramasamy
BACKGROUND: Perinatal depression (PND) is often under-treated and under-recognized. It has a negative impact on infant development and mother-child interactions. This study aims to estimate the prevalence of PND during pregnancy and in the postpartum period and the effect of sociodemographic factors, psychosocial stressors, and obstetric and neonatal factors on PND. METHODS: 166 antenatal mothers attending tertiary center, who completed the 1st-trimester, were evaluated on baseline sociodemographic, psychosocial, obstetric, neonatal, and post neonatal factors by using a semi-structured questionnaire...
January 2024: Indian Journal of Psychological Medicine
https://read.qxmd.com/read/38522947/association-of-hyaluronan-and-proteoglycan-link-protein-1-gene-with-the-need-of-home-oxygen-therapy-in-premature-japanese-infants-with-bronchopulmonary-dysplasia
#6
JOURNAL ARTICLE
Masato Ito, Ayumi Sasaki, Mitsuhiro Haga, Ayaka Iwatani, Eri Nishimura, Hirokazu Arai, Nobuhiko Nagano, Shutaro Suga, Shunsuke Araki, Asami Konishi, Yoshihiro Onouchi, Fumihiko Namba
BACKGROUND: Bronchopulmonary dysplasia (BPD) has a lasting effect on the respiratory function of infants, imposing chronic health burdens. BPD is influenced by various prenatal, postnatal, and genetic factors. This study explored the connection between BPD and home oxygen therapy (HOT), and then we examined the association between HOT and a specific single-nucleotide polymorphism (SNP) in the hyaluronan and proteoglycan link protein 1 ( HAPLN1 ) gene among premature Japanese infants. MATERIALS AND METHODS: Prenatal and postnatal data from 212 premature infants were collected and analyzed by four SNPs (rs975563, rs10942332, rs179851, and rs4703570) around HAPLN1 using the TaqMan polymerase chain reaction method...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/38513533/associations-of-maternal-sleep-trajectories-during-pregnancy-and-adverse-perinatal-outcomes-a-prospective-cohort-study
#7
JOURNAL ARTICLE
Zhi Li, Shanshan Cui, Hui Wang, Wenjuan Xiong, Yu Han, Wei Dai, Wei Xi, Tingkai Cui, Xin Zhang
OBJECTIVE: Sleep problems are common in pregnant women and sleep is altered during pregnancy. However, the associations between sleep trajectory patterns and adverse maternal and neonatal outcomes are unclear. The current study aims to identify sleep trajectory patterns and explore their associations with adverse perinatal outcomes in a prospective cohort study. METHODS: Pregnant women (N = 232) completed the Pittsburgh Sleep Quality Index each trimester during pregnancy in Tianjin, China...
March 16, 2024: Sleep Medicine
https://read.qxmd.com/read/38511669/second-twin-outcome-at-birth-retrospective-analysis-in-a-single-tertiary-centre-in-malaysia
#8
JOURNAL ARTICLE
Rahana Abd Rahman, Azmawati Mohammed Nawi, Shareena Ishak, Kartik Balaraman, Mohamad Azrai Abu, Siti Hajar Abd Azman, Aida Hani Kalok, Nor Azlin Mohamed Ismail, Zaleha Abdullah Mahdy, Shuhaila Ahmad
OBJECTIVES: To investigate factors associated with outcome of second twin during labour. METHODS: The study was a retrospective cohort study in a single tertiary centre in Malaysia from 2014 until 2018 involving all twin pregnancies delivered at or more than 24 weeks of gestation. RESULTS: Total of 409 twin pregnancies were included. Dichorionic twin comprises of 54.5 % (n=223) and 45.5 % (n=186) are monochorionic. Women with dichorionic pregnancies are significantly older (p<0...
March 22, 2024: Journal of Perinatal Medicine
https://read.qxmd.com/read/38511150/preterm-birth-a-neuroinflammatory-origin-for-metabolic-diseases
#9
REVIEW
Sihao Diao, Chao Chen, Alexandre Benani, Christophe Magnan, Juliette Van Steenwinckel, Pierre Gressens, Céline Cruciani-Guglielmacci, Alice Jacquens, Cindy Bokobza
Preterm birth and its related complications have become more and more common as neonatal medicine advances. The concept of "developmental origins of health and disease" has raised awareness of adverse perinatal events in the development of diseases later in life. To explore this concept, we propose that encephalopathy of prematurity (EoP) as a potential pro-inflammatory early life event becomes a novel risk factor for metabolic diseases in children/adolescents and adulthood. Here, we review epidemiological evidence that links preterm birth to metabolic diseases and discuss possible synergic roles of preterm birth and neuroinflammation from EoP in the development of metabolic diseases...
May 2024: Brain, behavior, & immunity health
https://read.qxmd.com/read/38510456/risk-of-adverse-perinatal-outcomes-among-women-with-clinical-and-subclinical-histopathological-chorioamnionitis
#10
JOURNAL ARTICLE
Andrea Olguín-Ortega, Ricardo Figueroa-Damian, Martha Leticia Palafox-Vargas, Enrique Reyes-Muñoz
INTRODUCTION: Histologic chorioamnionitis (HCA) is a placental inflammatory condition associated with adverse perinatal outcomes (APOs). This historical cohort study explores the risk of APOs in pregnant women with HCA and compares the impact of clinical chorioamnionitis (CCA) with subclinical chorioamnionitis (SCCA). METHODOLOGY: Placentas were evaluated by a perinatal pathologist tand all women with HCA were included. Two groups were integrated: (1) women with clinical chorioamnionitis (CCA) and (2) women with subclinical chorioamnionitis (SCCA)...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38504758/contributory-factors-to-early-neonatal-deaths-in-the-upper-east-regional-hospital-in-ghana
#11
JOURNAL ARTICLE
Francis K Wuni, Margaret W Kukeba, Yakubu Zakariah, Emmanuella A Nyaabila, Aiden S Saanwie
OBJECTIVE: This study examined factors identified during early neonatal death audits contributing to preventable newborn deaths at the Upper East Regional Hospital. METHOD: Data for this study was collected retrospectively from perinatal death audit forms using three data collectors. Data collection lasted two weeks, from 18th June to 2nd July 2021. The data collectors submitted 113 filled hard copy data collection forms. This was then entered into a designed Excel sheet and exported to STATA software version 15...
June 2023: Ghana Medical Journal
https://read.qxmd.com/read/38503546/can-we-improve-the-outcome-of-pregnancies-with-low-serum-papp-a-in-the-first-trimester
#12
JOURNAL ARTICLE
Valentina Tsibizova, Baydaa Al-Sannan, Anna Fedorova, Igor Govorov, Arun Meyyazhagan, Gian Carlo Di Renzo
OBJECTIVE: This study aimed to assess the impact of micronized progesterone (VMP4) supplementation on pregnancies with low serum pregnancy-associated plasma protein-A (PAPP-A) multiples of the median (MoM) values during first-trimester screening. METHODS: Out of 8933 patients evaluated, 116 pregnant women with low PAPP-A concentrations in their blood and no fetal chromosomal anomalies (CAs) were included. Three groups were formed: group 1 received VMP4 from 11 to 16 weeks (29 women, 25%), group 2 received VMP4 from 11 to 36 weeks (25 women, 21...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/38503544/twin-births-in-yucatan-mexico-during-2008-2020-trends-in-maternal-sociodemographic-factors-and-differences-in-birth-weight-and-length-according-to-sex-of-co-twin
#13
JOURNAL ARTICLE
Hugo Azcorra, Alina Dione Marin-Cardenas, Jairo R Villanueva-Toledo, Nina Mendez-Dominguez
Background: Over the years, there has been a noticeable increase in the incidence of multiple pregnancies, due in part to the increased use of assisted reproductive technologies in recent years. The increase in twin pregnancies constitutes a public health challenge due to the adverse outcomes sometimes they entail. Twin pregnancies inherently carry a higher risk of complications, and one of the critical associated factors is the risk of low birth weight. Twin birth weight discordance among different populations can be attributed to differences in non-shared environmental influences...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/38499386/evaluation-of-serum-levels-of-soluble-vascular-endothelial-sve-cadherin-in-early-and-late-onset-preeclampsia-serum-sve-cadherin-levels-in-preeclampsia
#14
JOURNAL ARTICLE
Abdullah Serdar Acikgöz, Koray Gök, Abdullah Tüten, Barış Kaya, Kübra Hamzaoğlu, Tuğba Kolomuç Gayretli, Eduard Malik, Onur Güralp
OBJECTIVE: Endothelial dysfunction is a major feature of preeclampsia. sVE-cadherin plays a role in the preservation and regulation of the endothelial barrier. For that reason, to evaluation of sVE-cadherin may help elucidate the disease pathophysiology of preeclampsia. METHODS: The sample size was calculated as a minimum of 46 pregnant women for each group based on serum sVE-Cadherin levels in a pilot study of 10 preeclamptic and 10 control groups. Hundred-twenty pregnancies complicated with early-onset ( n  = 60) and late-onset ( n  = 60) preeclampsia were compared with 120 gestational-age (GA)-matched (±1 week) uncomplicated pregnancies...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/38492741/-neurodevelopment-and-neuroprotection-in-young-children
#15
JOURNAL ARTICLE
Stéphane Marret, Alexandra Chadie, Jean-Baptiste Muller, Clément Chollat
In France, the most pessimistic estimates put the prevalence of neurodevelopmental disorders (NDD) at 15% of births. The two largest populations of newborns at highest risk of NDD are premature babies and babies born into siblings with one or more infants who already have an autism spectrum disorder or another NDD. The high prevalence of these disorders justifies a health promotion policy, centred on the child and his or her family. Prevention is based on the early identification of high-risk factors, by informing families and training pregnancy and early childhood professionals, and implementing perinatal prevention protocols for high-risk newborns (antenatal corticosteroid therapy and magnesium sulfate for women at risk of preterm delivery before 32 weeks, developmental care, therapeutic hypothermia for full-term infants with early neonatal encephalopathy presumed to be anoxic)...
March 14, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/38490252/design-and-implementation-of-a-didactic-curriculum-in-a-large-neonatal-perinatal-medicine-fellowship-program-a-single-center-experience
#16
JOURNAL ARTICLE
Shanmukha Mukthapuram, Beth Ann Johnson, Cara Slagle, John Erickson, Beena D Kamath-Rayne, Jennifer M Brady
OBJECTIVE:  Although the Accreditation Council for Graduate Medical Education and American Board of Pediatrics (ABP) provide regulations and guidance on fellowship didactic education, each program establishes their own didactic schedules to address these learning needs. Wide variation exists in content, educators, amount of protected educational time, and the format for didactic lectures. This inconsistency can contribute to fellow dissatisfaction, a perceived poor learning experience, and poor attendance...
March 15, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38488252/temporal-effects-of-caffeine-on-intrapulmonary-shunt-in-preterm-ventilated-infants
#17
JOURNAL ARTICLE
Ourania Kaltsogianni, Ravindra Bhat, Anne Greenough, Theodore Dassios
OBJECTIVES: We hypothesized that caffeine would be associated with a transient reduction in the right-to-left shunt and VA /Q. We aimed to explore the temporal effects of caffeine on right-to-left shunt, ventilation perfusion ratio (VA /Q) and shift of the oxyhaemoglobin dissociation curve (ODC) in premature ventilated infants. METHODS: Retrospective cohort study at a tertiary neonatal unit of infants born at less than 31 weeks of gestation that were mechanically ventilated on day three of life...
March 18, 2024: Journal of Perinatal Medicine
https://read.qxmd.com/read/38487084/metabolomic-analysis-of-the-human-placenta-reveals-perturbations-in-amino-acids-purine-metabolites-and-small-organic-acids-in-spontaneous-preterm-birth
#18
JOURNAL ARTICLE
Eva Cifkova, Rona Karahoda, Jaroslav Stranik, Cilia Abad, Marian Kacerovsky, Miroslav Lisa, Frantisek Staud
Spontaneous preterm delivery presents one of the most complex challenges in obstetrics and is a leading cause of perinatal morbidity and mortality. Although it is a common endpoint for multiple pathological processes, the mechanisms governing the etiological complexity of spontaneous preterm birth and the placental responses are poorly understood. This study examined placental tissues collected between May 2019 and May 2022 from a well-defined cohort of women who experienced spontaneous preterm birth (n = 72) and healthy full-term deliveries (n = 30)...
2024: EXCLI Journal
https://read.qxmd.com/read/38485520/efficacy-and-safety-of-oral-and-vaginal-administration-of-misoprostol-for-induction-of-labor-in-high-risk-obese-pregnant-women-with-hypertension-or-diabetes-mellitus
#19
JOURNAL ARTICLE
Shi Tian, Li Wang, Yi-Wei Han, Yan-Nan Liu, Feng-Qiu Li, Xiao-Hua Jin
OBJECTIVE: This study aims to compare the safety and efficacy of misoprostol administered orally and vaginally in obese pregnant women at term with either gestational hypertension or diabetes. METHODS: A total of 264 pregnant women were enrolled and categorized into two groups based on their primary condition: hypertension (134 cases) or diabetes mellitus (130 cases) and were further divided into subgroups for misoprostol administration: orally (Oral group) or vaginally (Vaginal group)...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/38485519/trial-of-labor-versus-elective-cesarean-delivery-for-patients-with-two-prior-cesarean-sections-a-systematic-review-and-meta-analysis
#20
REVIEW
Hui Mao, Pinghua Shen
OBJECTIVE: Cesarean section (CS) rates have been on the rise globally, leading to an increasing number of women facing the decision between a Trial of Labor after two Cesarean Sections (TOLAC-2) or opting for an Elective Repeat Cesarean Section (ERCS). This study evaluates and compares safety outcomes of TOLAC and ERCS in women with a history of two previous CS deliveries. METHODS: PubMed, MEDLINE, EMbase, and Cochrane Central Register of Controlled Trials (CENTRAL) databases were searched for studies published until 30 June 2023...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
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