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https://www.readbyqxmd.com/read/28813964/brain-computer-interface-combining-eye-saccade-two-electrode-eeg-signals-and-voice-cues-to-improve-the-maneuverability-of-wheelchair
#1
Ker-Jiun Wang, Lan Zhang, Bo Luan, Hsiao-Wei Tung, Quanfeng Liu, Jiacheng Wei, Mingui Sun, Zhi-Hong Mao
Brain-computer interfaces (BCIs) largely augment human capabilities by translating brain wave signals into feasible commands to operate external devices. However, many issues face the development of BCIs such as the low classification accuracy of brain signals and the tedious human-learning procedures. To solve these problems, we propose to use signals associated with eye saccades and blinks to control a BCI interface. By extracting existing physiological eye signals, the user does not need to adapt his/her brain waves to the device...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813948/robotic-assistance-for-performing-vocational-rehabilitation-activities-using-baxbot
#2
Kyle Ashley, Redwan Alqasemi, Rajiv Dubey
Activities of Daily Living (ADL's) refer to tasks that people do on a daily basis, such as self-feeding, cleaning the house, or bathing. These activities often require a degree of functional mobility that may be outside the ability of a person suffering from cognitive or physical impairment. This work describes methods of performing ADL's with a mobile robotic system. We examined the needs of potential users and caregivers through surveys to determine the most needed applications for robotic assistance. Using this information, we extended the functionality of our BaxBot mobile robotic system to provide meaningful, autonomous assistance in performing three specific ADL's with minimal user interaction...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813627/the-impact-on-resource-utilization-of-supportive-care-consults-on-patients-at-the-university-of-north-carolina-hospital-2010-2012
#3
Kristen Westfall, Dominic Moore, Matthew Meeneghan, Sandra Jarr, John Valgus, Stephen Bernard
BACKGROUND: Cancer patients have a high rate of emergency department (ED) visits and inpatient hospitalizations (IHs) that may be reduced by use of outpatient palliative care services. OBJECTIVE: To determine whether the outpatient adult palliative care service at the University of North Carolina (UNC) Hospital, begun in 2008, reduced the frequency of ED visits and IH during a two-year period. DESIGN: The charts of patients with lung cancer or head and neck cancer seen by the supportive care service from 2010 to 2011, and of a contemporaneous set of potential consults that were not seen, were retrospectively reviewed to determine the impact of this care delivery model...
August 16, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28813479/metabolomic-profiling-of-amines-in-sepsis-predicts-changes-in-nos-canonical-pathways
#4
Abel Tesfai, Niall MacCallum, Nicholas S Kirkby, Hime Gashaw, Nicola Gray, Elizabeth Want, Gregory J Quinlan, Sharon Mumby, James M Leiper, Mark Paul-Clark, Blerina Ahmetaj-Shala, Jane A Mitchell
RATIONALE: Nitric oxide synthase (NOS) is a biomarker/target in sepsis. NOS activity is driven by amino acids, which cycle to regulate the substrate L-arginine in parallel with cycles which regulate the endogenous inhibitors ADMA and L-NMMA. The relationship between amines and the consequence of plasma changes on iNOS activity in early sepsis is not known. OBJECTIVE: Our objective was to apply a metabolomics approach to determine the influence of sepsis on a full array of amines and what consequence these changes may have on predicted iNOS activity...
2017: PloS One
https://www.readbyqxmd.com/read/28812740/higher-order-interactions-capture-unexplained-complexity-in-diverse-communities
#5
Margaret M Mayfield, Daniel B Stouffer
Natural communities are well known to be maintained by many complex processes. Despite this, the practical aspects of studying them often require some simplification, such as the widespread assumption that direct, additive competition captures the important details about how interactions between species impact community diversity. More complex non-additive 'higher-order' interactions are assumed to be negligible or absent. Notably, these assumptions are poorly supported and have major consequences for the accuracy with which patterns of natural diversity are modelled and explained...
February 17, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28812402/older-persons-experiences-of-a-home-based-exercise-program-with-behavioral-change-support
#6
Marina Arkkukangas, Annelie J Sundler, Anne Söderlund, Staffan Eriksson, Ann-Christin Johansson
BACKGROUND: It is a challenge to promote exercise among older persons. Knowledge is needed regarding the maintenance of exercise aiming at preventing falls and promoting health and well-being in older persons. PURPOSE: This descriptive study used a qualitative inductive approach to describe older persons' experiences of a fall-preventive, home-based exercise program with support for behavioral change. METHODS: Semi-structured interviews were conducted with 12 elderly persons aged 75 years or older, and a qualitative content analysis was performed...
August 16, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28811351/content-and-construct-validity-reliability-and-responsiveness-of-the-rheumatoid-arthritis-flare-questionnaire-omeract-2016-workshop-report
#7
Susan J Bartlett, Skye P Barbic, Vivian P Bykerk, Ernest H Choy, Rieke Alten, Robin Christensen, Alfons den Broeder, Bruno Fautrel, Daniel E Furst, Francis Guillemin, Sarah Hewlett, Amye L Leong, Anne Lyddiatt, Lyn March, Pamela Montie, Christoph Pohl, Marieke Scholte Voshaar, Thasia G Woodworth, Clifton O Bingham
OBJECTIVE: The Outcome Measures in Rheumatology (OMERACT) Rheumatoid Arthritis (RA) Flare Group was established to develop a reliable way to identify and measure RA flares in randomized controlled trials (RCT). Here, we summarized the development and field testing of the RA Flare Questionnaire (RA-FQ), and the voting results at OMERACT 2016. METHODS: Classic and modern psychometric methods were used to assess reliability, validity, sensitivity, factor structure, scoring, and thresholds...
August 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28810522/unrepresented-community-odour-impact-improving-engagement-strategies
#8
J E Hayes, R M Fisher, R J Stevenson, C Mannebeck, R M Stuetz
Complaints for odour causing industry continue to increase in numeracy and severity. One assessment approach using Gas Chromatography-Mass Spectrometry/Olfactometry (GC-MS/O), has been used primarily to identify priority odourants within a standardised panel. We investigated the variation of response between participants of average and high olfactory sensitivity, and discovered that current GC-MS/O methodologies do not represent the entirety of community odour impact. Based on these results we constructed a Biosolids Processing Odour Wheel followed by a Community Odour Wheel for use by untrained community members and site operators...
August 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28810454/ineffectiveness-of-commercial-weight-loss-programs-for-achieving-modest-but-meaningful-weight-loss-systematic-review-and-meta-analysis
#9
Samantha M McEvedy, Gillian Sullivan-Mort, Siân A McLean, Michaela C Pascoe, Susan J Paxton
This study collates existing evidence regarding weight loss among overweight but otherwise healthy adults who use commercial weight-loss programs. Systematic search of 3 databases identified 11 randomized controlled trials and 14 observational studies of commercial meal-replacement, calorie-counting, or pre-packaged meal programs which met inclusion criteria. In meta-analysis using intention-to-treat data, 57 percent of individuals who commenced a commercial weight program lost less than 5 percent of their initial body weight...
May 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28809693/simultaneous-projection-and-positioning-of-laser-projector-pixels
#10
Yuki Kitajima, Daisuke Iwai, Kosuke Sato
This paper presents a novel projected pixel localization principle for online geometric registration in dynamic projection mapping applications. We propose applying a time measurement of a laser projector raster-scanning beam using a photosensor to estimate its position while the projector displays meaningful visual information to human observers. Based on this principle, we develop two types of position estimation techniques. One estimates the position of a projected beam when it directly illuminates a photosensor...
August 10, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28809649/linking-neuroscience-function-and-intervention-a-scoping-review-of-sensory-processing-and-mental-illness
#11
Antoine L Bailliard, Stephanie C Whigham
PURPOSE: Sensory approaches to mental illness are increasingly prominent in occupational therapy. Despite indicators of efficacy, a paucity of literature supports these approaches. This article provides a scoping review of research on the relationship between sensory processing and mental illness. METHOD: Using Arksey and O'Malley's (2005) framework, we mapped this area of research and identified gaps in the knowledge base. We searched PubMed, CINAHL Plus, PsycINFO, OTseeker, and the Cochrane Library using the terms sensory and mental health...
September 2017: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://www.readbyqxmd.com/read/28808995/high-resolution-parallel-reaction-monitoring-with-electron-transfer-dissociation-for-middle-down-proteomics-an-application-to-study-the-quantitative-changes-induced-by-histone-modifying-enzyme-inhibitors-and-activators
#12
Michael J Sweredoski, Annie Moradian, Sonja Hess
With the advent of new methodologies, proteomics-based assays are increasingly used to study the efficacy of drugs on a molecular level. For these studies to be meaningful, the proteomics assays need to be sensitive, selective, accurate, and reproducible. This is often accomplished through a targeted approach, either using single or multiple reaction monitoring (SRM/MRM) or, more recently, parallel reaction monitoring (PRM). In PRM, the parallel detection of all product ions in a high-resolution mass spectrometer affords higher selectivity than SRM/MRM...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28808905/a-pharmacokinetic-bioequivalence-study-comparing-pirfenidone-tablet-and-capsule-dosage-forms-in-healthy-adult-volunteers
#13
Lin Pan, Paula Belloni, Han Ting Ding, Jianshuang Wang, Christopher M Rubino, Wendy S Putnam
INTRODUCTION: Pirfenidone film-coated tablets were developed to offer an alternative to the marketed capsule formulation. This study assessed the bioequivalence of the tablet and capsule formulations under fed and fasted states. METHODS: A Phase I, open-label, randomized, four-treatment-period, four-sequence, crossover pharmacokinetics study (NCT02525484) was conducted. Each subject received an 801-mg single dose of pirfenidone as three 267-mg capsules or one 801-mg tablet under fasted and fed conditions...
August 14, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28808832/factor-structure-of-teacher-ratings-of-the-odd-symptoms-in-children
#14
Rapson Gomez, Vasileios Stavropoulos, George Van Doorn
This study used confirmatory factor analysis (CFA) to determine the best model for Oppositional Defiant Disorder (ODD) symptoms in children aged 3 to 15 years, as presented in the Disruptive Behavior Rating Scale. Teachers' ratings of the ODD symptoms of 213 children from general community schools in Australia were obtained. The findings provided most support for a bifactor model based on Stringaris and Goodman's [1] three-factor model (primary factors for irritable, hurtful, and headstrong). The general factor, but not the group factors in the model, showed high omega hierarchical and explained common variance...
August 15, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/28808817/electrophysiological-modulation-in-an-effort-to-complete-illusory-figures-configuration-illusory-contour-and-closure-effects
#15
Tommaso Poscoliero, Massimo Girelli
Figure recognition process: From the coarse configuration standing from the background to the closure of a meaningful shape, was investigated by ERP technique. ERP components at different latencies from stimulus onset allowed to tap into the figure recognition process at discrete time-points when different cognitive operations take place. In this study, we present two experiments where the support-ratio (SR) of illusory figures was manipulated to vary continuously the recognition of geometrical figures. In the first experiment three shapes were used to vary the SR and the P1 component (80-130 ms) was modulated by the configuration-effect explained, in part for the first time, with the unbalanced physical stimulation between upper and lower visual field...
August 14, 2017: Brain Topography
https://www.readbyqxmd.com/read/28808428/a-comparison-of-concurrent-cisplatin-versus-cetuximab-with-radiotherapy-in-locally-advanced-head-and-neck-cancer-a-bi-institutional-analysis
#16
William A Stokes, Whitney A Sumner, Kiersten L Breggren, John T Rathbun, David Raben, Jessica D McDermott, Gregory Gan, Sana D Karam
AIM: To present our experience comparing cisplatin- and cetuximab-based radiotherapy for locally-advanced head and neck squamous cell carcinoma. BACKGROUND: The comparative effectiveness of cisplatin-based chemoradiotherapy (CRT) versus cetuximab-based bioradiotherapy (BRT) for locally-advanced head and neck squamous cell carcinoma (LAHNSCC) continues to be explored. MATERIALS AND METHODS: Outcomes of LAHNSCC patients treated with CRT (125) or BRT (34) at two institutions were compared retrospectively, with attention to overall survival (OS), cancer-specific survival (CSS), locoregional control (LRC), and distant control (DC)...
September 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/28808362/a-study-on-the-psychometric-properties-of-revised-nonverbal-pain-scale-and-original-nonverbal-pain-scale-in-iranian-nonverbal-ventilated-patients
#17
Hoda Chookalayi, Mehdi Heidarzadeh, Mohammad Hasanpour, Sajjad Jabrailzadeh, Fatemeh Sadeghpour
BACKGROUND AND AIMS: The nonverbal pain scale is one of the instruments which study pain in nonverbal-ventilated patients with regard to the changes of behavioral and physiological indices. The purpose of the study is to survey the psychometric properties of revised-nonverbal pain scale (R-NVPS) and original-nonverbal pain scale (O-NVPS) in ventilated patients hospitalized in critical care units. MATERIALS AND METHODS: Four nurses studied pain in sixty patients hospitalized in trauma, medical, neurology, and surgical critical care units using R-NVPS and O-NVPS at six times (before, during, and after nociceptive and nonnociceptive procedures)...
July 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28808356/the-gist-of-delay-of-gratification-understanding-and-predicting-problem-behaviors
#18
Valerie F Reyna, Evan A Wilhelms
Delay of gratification captures elements of temptation and self-denial that characterize real-life problems with money and other problem behaviors such as unhealthy risk taking. According to fuzzy-trace theory, decision makers mentally represent social values such as delay of gratification in a coarse but meaningful form of memory called "gist." Applying this theory, we developed a gist measure of delay of gratification that does not involve quantitative trade-offs (as delay discounting does) and hypothesize that this construct explains unique variance beyond sensation seeking and inhibition in accounting for problem behaviors...
April 2017: Journal of Behavioral Decision Making
https://www.readbyqxmd.com/read/28807819/carrier-characteristics-influence-the-kinetics-of-passive-drug-loading-into-lipid-nanoemulsions
#19
Katrin Göke, Heike Bunjes
Passive loading as a novel screening approach is a material-saving tool for the efficient selection of a suitable colloidal lipid carrier system for poorly water soluble drug candidates. This method comprises incubation of preformed carrier systems with drug powder and subsequent determination of the resulting drug load of the carrier particles after removal of excess drug. For reliable routine use and to obtain meaningful loading results, information on the kinetics of the process is required. Passive loading proceeds via a dissolution-diffusion based mechanism, where drug surface area and drug water solubility are key parameters for fast passive loading...
August 11, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28807753/a-critical-evaluation-of-validity-and-utility-of-translational-imaging-in-pain-and-analgesia-utilizing-functional-imaging-to-enhance-the-process
#20
REVIEW
Jaymin Upadhyay, Christian Geber, Richard Hargreaves, Frank Birklein, David Borsook
Assessing clinical pain and metrics related to function or quality of life predominantly relies on patient reported subjective measures. These outcome measures are generally not applicable to the preclinical setting where early signs pointing to analgesic value of a therapy are sought, thus introducing difficulties in animal to human translation in pain research. Evaluating brain function in patients and respective animal model(s) has the potential to characterize mechanisms associated with pain or pain-related phenotypes and thereby provide a means of laboratory to clinic translation...
August 11, 2017: Neuroscience and Biobehavioral Reviews
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