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https://www.readbyqxmd.com/read/28724186/inositol-hexaphosphate-insp6-as-an-effective-topical-treatment-for-patients-receiving-adjuvant-chemotherapy-after-breast-surgery
#1
S Proietti, V Pasta, A Cucina, C Aragona, E Palombi, I Vucenik, M Bizzarri
OBJECTIVE: Oral treatment with inositol hexaphosphate (InsP6) has shown to be efficient in decreasing adverse effects in patients with breast cancer under chemotherapy. This study was aimed at evaluating and comparing the efficacy of topical InsP6 in improving quality of life in women treated with anticancer drugs. PATIENTS AND METHODS: The study was a double-blind, randomized controlled trial (RCT) with allocation concealment of 20 patients in two groups, one (experimental) applied 4% topical formulation of InsP6 once a day, whereas the second one (control) a gel containing hyaluronic acid...
June 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28722761/a-meta-ethnographic-synthesis-of-midwives-and-nurses-experiences-of-adverse-labour-and-birth-events
#2
REVIEW
Rakime Elmir, Jackie Pangas, Hannah Dahlen, Virginia Schmied
INTRODUCTION: Health professionals are frequently exposed to traumatic events due to the nature of their work. While traumatic and adverse labour and birth events experienced by women are well researched, less attention has been given to midwives' and nurses' experiences of these events and the impact it has on their lives. AIM: To undertake a meta-ethnographic study of midwives' and nurses' experiences of adverse labour and birth events. METHODS: Scopus, CINHAL PLUS, MEDLINE and PUBMED databases were searched using subject headings and keywords...
July 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28722028/fat-free-mass-depletion-in-patients-with-copd-in-brazil-development-of-a-new-cutoff-point-and-its-relation-with-mortality-and-extrapulmonary-manifestations
#3
A Travassos, A Rodrigues, K C Furlanetto, L Donária, G W Bisca, A G Nellessen, F Pitta, N A Hernandes
BACKGROUND/OBJECTIVES: None of the cutoff points for fat-free mass index (FFMI) were tested for the Brazilian population, and it is unknown whether the available ones are able to discriminate extrapulmonary disease manifestations. This cross-sectional study aims to develop and validate a cutoff point for FFM depletion based on Brazilian patients with chronic obstructive pulmonary disease (COPD) and to verify its association and of previously published cutoffs with extrapulmonary manifestations...
July 19, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28721837/effects-of-progressive-resistance-training-combined-with-a-protein-enriched-lean-red-meat-diet-on-health-related-quality-of-life-in-elderly-women-secondary-analysis-of-a-4-month-cluster-randomised-controlled-trial
#4
Susan J Torres, Sian Robinson, Liliana Orellana, Stella L O'Connell, Carley A Grimes, Niamh L Mundell, David W Dunstan, Caryl A Nowson, Robin M Daly
Resistance training (RT) and increased dietary protein are recommended to attenuate age-related muscle loss in the elderly. This study examined the effect of a lean red meat protein-enriched diet combined with progressive resistance training (RT+Meat) on health-related quality of life (HR-QoL) in elderly women. In this 4-month cluster randomised controlled trial, 100 women aged 60-90 years (mean 73 years) from self-care retirement villages participated in RT twice a week and were allocated either 160 g/d (cooked) lean red meat consumed across 2 meals/d, 6 d/week or ≥1 serving/d (25-30 g) carbohydrates (control group, CRT)...
June 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28721649/health-related-quality-of-life-for-women-ever-experiencing-infertility-or-difficulty-staying-pregnant
#5
Sheree L Boulet, Ruben A Smith, Sara Crawford, Dmitry M Kissin, Lee Warner
INTRODUCTION: Information on the health-related quality of life (HRQOL) for women with infertility is limited and does not account for the co-occurrence of chronic conditions or emotional distress. METHODS: We used data from state-added questions on reproductive health included in the 2013 Behavioral Risk Factor Surveillance System in seven states. HRQOL indicators included: self-reported health status; number of days in the past 30 days when physical and mental health was not good; number of days in the past 30 days that poor physical or mental health limited activities...
July 18, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28721628/disease-activity-handgrip-strengths-and-hand-dexterity-in-patients-with-rheumatoid-arthritis
#6
D Palamar, G Er, R Terlemez, I Ustun, G Can, M Saridogan
Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting the hand joints and leading to impairment in hand functions. Evaluation of functional impairment is necessary for assessing patient's quality of life, disease activity, and treatment outcome. To date, many scientific studies assessed the disease activity of patients with RA, but little attention has been carried out to assess these patients' hand functions and dexterity. The purposes of this study were to determine the clinical relevance of the Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH), hand dexterity with the Purdue Pegboard Test (PPT), and handgrip strength and pinch strengths of RA patients and to look into their relation between each other...
July 18, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28721435/effect-of-a-combined-tai-chi-resistance-training-and-dietary-intervention-on-cognitive-function-in-obese-older-women
#7
F Xu, M J Delmonico, I E Lofgren, K M Uy, S A Maris, D Quintanilla, A G Taetzsch, J Letendre, L Mahler
Cognitive decline in older adults is a major public health problem and can compromise independence and quality of life. Exercise and diet have been studied independently and have shown to be beneficial for cognitive function, however, a combined Tai Chi, resistance training, and diet intervention and its influence on cognitive function has not been undertaken. The current study used a 12-week non-randomized research design with experiment and control groups to examine the effect of a combined Tai Chi, resistance training, and diet intervention on cognitive function in 25 older obese women...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/28720359/functional-outcomes-following-radical-cystectomy-in-women-with-bladder-cancer-a-systematic-review
#8
REVIEW
Angela B Smith, Karen Crowell, Michael E Woods, Eric M Wallen, Raj S Pruthi, Matthew E Nielsen, Cheryl T Lee
CONTEXT: Gender-specific functional and health-related quality of life (HRQOL) outcomes following radical cystectomy (RC) for bladder cancer (BCa) remain unclear, with many studies excluding women from the study population. OBJECTIVE: To better characterize female-specific functional outcomes following RC and urinary diversion for BCa. EVIDENCE ACQUISITION: We performed a critical review of PubMed/Medline and Embase in August 2015 according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis statement...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720039/the-revamp-trial-to-evaluate-hiv-resistance-testing-in-sub-saharan-africa-a-case-study-in-clinical-trial-design-in-resource-limited-settings-to-optimize-effectiveness-and-cost-effectiveness-estimates
#9
Mark J Siedner, Mwebesa B Bwana, Mahomed-Yunus S Moosa, Michelle Paul, Selvan Pillay, Suzanne McCluskey, Isaac Aturinda, Kevin Ard, Winnie Muyindike, Pravikrishnen Moodley, Jaysingh Brijkumar, Tamlyn Rautenberg, Gavin George, Brent Johnson, Rajesh T Gandhi, Henry Sunpath, Vincent C Marconi
BACKGROUND: In sub-Saharan Africa, rates of sustained HIV virologic suppression remain below international goals. HIV resistance testing, while common in resource-rich settings, has not gained traction due to concerns about cost and sustainability. OBJECTIVE: We designed a randomized clinical trial to determine the feasibility, effectiveness, and cost-effectiveness of routine HIV resistance testing in sub-Saharan Africa. APPROACH: We describe challenges common to intervention studies in resource-limited settings, and strategies used to address them, including: (1) optimizing generalizability and cost-effectiveness estimates to promote transition from study results to policy; (2) minimizing bias due to patient attrition; and (3) addressing ethical issues related to enrollment of pregnant women...
July 18, 2017: HIV Clinical Trials
https://www.readbyqxmd.com/read/28720024/the-wayfinding-questionnaire-a-clinically-useful-self-report-instrument-to-identify-navigation-complaints-in-stroke-patients
#10
N K de Rooij, M H G Claessen, I J M van der Ham, M W M Post, J M A Visser-Meily
Post-stroke navigation complaints are frequent (about 30%) and intervention is possible, but there is no assessment instrument to identify patients with navigation complaints. We therefore studied the clinical validity of the Wayfinding Questionnaire (WQ) in a cross-sectional study with 158 chronic stroke patients and 131 healthy controls. Patients with low (more navigation complaints) versus normal WQ scores were compared for demographics, stroke characteristics, emotional and cognitive complaints, and health-related quality of life (HRQoL)...
July 18, 2017: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/28719716/the-sophono-bone-conduction-system-surgical-audiologic-and-quality-of-life-outcomes
#11
Timothy Mclean, Irumee Pai, Andrew Philipatos, Michael Gordon
We prospectively evaluated the surgical, audiologic, and quality-of-life outcomes in 5 patients-2 men and 3 women, aged 22 to 64 years (mean: 41.8)-who were implanted with the Sophono Alpha 2 MPO Processor. The indications for implantation of this bone-conduction device included recurrent ear canal infections with hearing aids (n = 3), single-sided deafness (n = 1), and patient preference in view of difficulty using a conventional hearing aid (n = 1). In addition to the patient with single-sided deafness, 3 patients had a bilateral mixed hearing loss and 1 had a bilateral conductive hearing loss...
July 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28719105/screening-for-hazardous-drinking-in-nursing-home-residents-evaluating-the-validity-of-the-current-cut-offs-of-the-alcohol-use-disorder-identification-test-consumption-questions-audit-c-by-using-ethyl-glucuronide-in-hair-hetg
#12
Monika Dreher-Weber, Anton-Rupert Laireiter, Anton Kühberger, Isabella Kunz, Michel Yegles, Tina Binz, Hans-Jürgen Rumpf, Rainer Hoffmann, Verena Schmidt, Siegfried Lang, Friedrich M Wurst
BACKGROUND: Because of physiological changes, elderly people are much more exposed to the adverse effects of alcohol. Therefore, hazardous drinking is defined at lower levels as compared to younger adults. This work aims to evaluate the validity of the current cut off levels of the Alcohol Use Disorder Identification Test - Consumption questions (AUDIT-C) to detect hazardous drinking in the elderly by using ethyl glucuronide in hair (HEtG). METHODS: In a border region between Austria and Germany, 344 nursing home residents were included from 33 of the 107 nursing homes...
July 18, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28718251/comparison-of-dietary-practices-and-body-mass-index-among-educated-housewives-and-working-women-in-karachi
#13
Lubna Raza, Tahira Mohsin Ali, Abid Hasnain
BACKGROUND: Body Mass Index (BMI) is considered as a major determinant of health. The objective of study was to find out differences between dietary practices, as well as BMI in educated housewives and working woman. It is supposed that both study groups may have difference in work pressures with resultant diverse preferences for food. This can affect health status particularly in relation to obesity in women. Furthermore, we selected participants with 14 years' education expecting basic awareness of healthful diet...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28718223/self-management-of-stress-urinary-incontinence-via-a-mobile-app-2-year-follow-up-of-a-randomized-controlled-trial
#14
Victoria Hoffman, Lars Söderström, Eva Samuelsson
We investigated the long-term effects of using a mobile app to treat stress urinary incontinence with a focus on pelvic floor muscle training (PFMT) MATERIAL AND METHODS: A previous randomized controlled trial of 123 women aged 27-72 years found that 3 months of self-managing stress urinary incontinence with support from the Tät(®) app was effective. We followed-up the women in the app group (n=62) two years after the initial trial with the same primary outcomes for symptom severity (International Consultation on Incontinence Questionnaire Short Form [ICIQ-UI SF]) and condition-specific quality of life (ICIQ-Lower Urinary Tract Symptom Quality of Life [ICIQ-LUTSqol]) and compared the scores with those at baseline RESULTS: Of the 62 women, 61 and 46 (75...
July 17, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28718162/robotic-sacrocolpopexy-is-it-the-treatment-of-choice-for-advanced-apical-pelvic-organ-prolapse
#15
REVIEW
Janine L Oliver, Ja-Hong Kim
PURPOSE OF REVIEW: Pelvic organ prolapse (POP) is a highly prevalent condition among women that, although non-life threatening, can significantly impact daily activities and quality of life (QOL). Sacrocolpopexy (SC) has been touted by many as the "gold standard," citing superior anatomic success rates compared to transvaginal approaches for apical prolapse repair. In line with current trends throughout the surgical field, robotic-assisted laparoscopic sacrocolpopexy (RSC) has rapidly gained popularity...
September 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28718004/impact-of-gastrointestinal-events-on-patient-reported-outcomes-in-asia-pacific-women-with-osteoporosis-baseline-results-of-the-music-os-ap-study
#16
A Modi, P R Ebeling, M S Lee, Y K Min, A Mithal, X Yang, S Baidya, S Sen, S Sajjan
The purpose of this study was to describe the impact of gastrointestinal events on patient-reported outcomes and health care resource use among Asia-Pacific women with postmenopausal osteoporosis. The results of this study show that gastrointestinal events decreased adherence, treatment satisfaction, and quality of life in Asia-Pacific women with postmenopausal osteoporosis. PURPOSE: This study aimed to describe the impact of gastrointestinal (GI) events on patient-reported outcomes and health care resource use among Asia-Pacific women with postmenopausal osteoporosis...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28717811/effect-on-body-weight-quality-of-life-and-appetite-following-individualized-nutritional-counselling-to-home-living-elderly-after-rehabilitation-an-open-randomized-trial
#17
J Andersson, E Hulander, E Rothenberg, P Ole Iversen
OBJECTIVES: We examined if individually-adapted nutritional counselling could prevent > 5% weight loss among elderly patients 3 months after discharge from a rehabilitation institution. In addition we assessed quality of life (QoL) and appetite. DESIGN: An open, randomized trial. SETTING: Godthaab Health and Rehabilitation Institution in Bærum, Norway. PARTICIPANTS: Patients identified as being undernourished or at risk of disease-related malnutrition using the Nutritional Risk Screening tool NRS-2002...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28717714/phenotype-and-treatment-of-breast-cancer-in-hiv-positive-and-negative-women-in-cape-town-south-africa
#18
Lizanne Langenhoven, Pieter Barnardt, Alfred I Neugut, Judith S Jacobson
PURPOSE: An estimated 5.9 million people in South Africa are infected with HIV. Because antiretroviral therapy has made infection with HIV a treatable, chronic condition, HIV-infected individuals are now surviving to middle and older age. We investigated the implications of HIV status for breast cancer in South Africa. METHODS: We compared clinical and demographic characteristics of women newly diagnosed with a first primary breast cancer at Tygerberg Hospital, Cape Town, South Africa, from January 2010 to December 2011 by HIV status...
October 2016: Journal of Global Oncology
https://www.readbyqxmd.com/read/28716637/update-on-the-management-of-abnormal-uterine-bleeding
#19
Yael Levy-Zauberman, Anne-Gaëlle Pourcelot, Perrine Capmas, Hervé Fernandez
Abnormal uterine bleeding (AUB) is a common complaint that affects large numbers of women from puberty to menopause. It negatively affects health by causing anemia, and impacts the quality of life of women affected. AUB also has an economic impact for both women and society. Therefore, it should not be under- or overestimate and diagnosis, investigations and treatment should be proposed, taking into account the scientific data available in the current state of medical knowledge. Using the new terminology and etiologic classification of AUB is essential to communicate properly around the subject...
July 14, 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/28716350/progress-and-priorities-for-reproductive-maternal-newborn-and-child-health-in-kenya-a-countdown-to-2015-country-case-study
#20
Emily C Keats, Anthony Ngugi, William Macharia, Nadia Akseer, Emma Nelima Khaemba, Zaid Bhatti, Arjumand Rizvi, John Tole, Zulfiqar A Bhutta
BACKGROUND: Progress in reproductive, maternal, newborn, and child health (RMNCH) in Kenya has been inconsistent over the past two decades, despite the global push to foster accountability, reduce child mortality, and improve maternal health in an equitable manner. Although several cross-sectional assessments have been done, a systematic analysis of RMNCH in Kenya was needed to better understand the push and pull factors that govern intervention coverage and influence mortality trends...
August 2017: Lancet Global Health
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