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https://www.readbyqxmd.com/read/27911424/-effectiveness-of-soft-contact-lenses-in-severe-keratoconjunctivitis-sicca-treated-with-local-immunosuppressive-therapy
#1
T N Safonova, O V Gladkova, V I Boev, A A Fedorov
AIM: To study the effectiveness of soft contact lenses in severe keratoconjunctivitis sicca (KCS) treated with local immunosuppressive therapy. MATERIAL AND METHODS: We have examined 41 patients (60 eyes) with severe KCS, including 3 men (4 eyes) and 38 women (56 eyes) aged from 27 to 76 years. Group 1 consisted of 22 persons (30 eyes) who were prescribed cyclosporine А 0.05% instillations 2 times daily, artificial tears, and soft contact lenses. Group 2 consisted of 19 patients (30 eyes) who received instillations of cyclosporine А 0...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27909125/ageing-deep-vein-thrombosis-and-male-gender-predict-poor-outcome-after-acute-achilles-tendon-rupture
#2
E Domeij- Arverud, P Anundsson, E Hardell, G Barreng, G Edman, A Latifi, F Labruto, P W Ackermann
AIMS: Patients with an acute Achilles tendon rupture (ATR) take a long time to heal, have a high incidence of deep vein thrombosis (DVT) and widely variable functional outcomes. This variation in outcome may be explained by a lack of knowledge of adverse factors, and a subsequent shortage of appropriate interventions. PATIENTS AND METHODS: A total of 111 patients (95 men, 16 women; mean age 40.3, standard deviation 8.4) with an acute total ATR were prospectively assessed...
December 2016: Bone & Joint Journal
https://www.readbyqxmd.com/read/27909086/the-12-item-psoriatic-arthritis-impact-of-disease-questionnaire-construct-validity-reliability-and-interpretability-in-a-clinical-setting
#3
Marco Di Carlo, Andrea Becciolini, Valentina Lato, Chiara Crotti, Ennio Giulio Favalli, Fausto Salaffi
OBJECTIVE: To study, in a real-life setting, the construct validity, the reliability, and the interpretability of the 12-item Psoriatic Arthritis Impact of Disease (PsAID-12) questionnaire in patients with psoriatic arthritis (PsA). METHODS: In 144 consecutive patients with PsA (81 men and 63 women, mean age of 51.4 ± 12.8 yrs, and 77 receiving biologic treatment), the PsAID-12 and other patient-reported outcomes (PRO) were collected, such as the Dermatology Life Quality Index...
December 1, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27908262/sleep-alterations-in-non-demented-older-individuals-the-role-of-cortisol
#4
Ana Belén Castelló-Domenech, Vanessa Ibáñez Del Valle, Julio Fernández-Garrido, Mary Martínez-Martínez, Omar Cauli
BACKGROUND: Sleep alterations can impair quality of life and contribute to disease progression but they, and their features and contributing factors, are rarely analysed in institutionalised older individuals. In this study we investigated sleep alterations, the factors involved, and the role of cortisol in sleep-related problems in institutionalised individuals. METHODS: We conducted a descriptive cross-sectional study in participants living in nursing homes in Valencia (Spain); sleep alterations were determined based on two validated tools: the Athens insomnia scale and Oviedo sleep questionnaire...
November 30, 2016: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/27908212/are-crh-ngf-as-psychoneuroimmune-regulators-in-women-with-polycystic-ovary-syndrome
#5
F Z Zangeneh, M M Naghizadeh, M Bagheri, M Jafarabadi
PURPOSE: Polycystic ovary syndrome (PCOS) affects quality of life and can worsen anxiety and depression either due to the features of PCOS or due to the diagnosis of a chronic disease. Corticotrophin-releasing hormone (CRH) and nerves growth factor (NGF) are the modulator for the actions of the sympathetic nervous and immune systems. METHODS: In total, 171 women divided into two groups: study and control groups. Serum CRH, NGF, and interleukins: IL-1α. IL-1β, 17A, and TNFα were determined by ELISA Kits in both groups...
December 2, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27907897/cost-effectiveness-of-embryo-transfer-strategies-a-decision-analytic-model-using-long-term-costs-and-consequences-of-singletons-and-multiples-born-as-a-consequence-of-ivf
#6
M M J van Heesch, A D I van Asselt, J L H Evers, M A H B M van der Hoeven, J C M Dumoulin, C E M van Beijsterveldt, G J Bonsel, R H M Dykgraaf, J B van Goudoever, C Koopman-Esseboom, W L D M Nelen, K Steiner, P Tamminga, N Tonch, H L Torrance, C D Dirksen
STUDY QUESTION: What is the cost-effectiveness of elective single embryo transfer (eSET) versus double embryo transfer (DET) strategies from a societal perspective, when applying a time horizon of 1, 5 and 18 years? SUMMARY ANSWER: From a short-term perspective (1 year) it is cost-effective to replace DET with single embryo transfer; however when intermediate- (5 years) and long-term (18 years) costs and consequences are incorporated, DET becomes the most cost-effective strategy, given a ceiling ratio of €20 000 per quality-adjusted life years (QALY) gained...
November 2016: Human Reproduction
https://www.readbyqxmd.com/read/27906807/quality-of-life-and-sexual-distress-in-women-with-erosive-vulvovaginal-lichen-planus
#7
Harriet Cheng, Amanda Oakley, John V Conaglen, Helen M Conaglen
OBJECTIVES: Erosive vulvovaginal lichen planus (EVLP) is a chronic and painful genital dermatosis. Little is published about its impact on quality of life. This study aimed to evaluate quality of life and sexual function in women with EVLP. MATERIALS AND METHODS: Women with genital dermatoses were surveyed using the Dermatology Life Quality Index (DLQI) and Hospital Depression and Anxiety Scales. A subgroup completed the Female Sexual Distress Scale and Female Sexual Function Index subscales...
November 30, 2016: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27906472/long-term-clinical-impact-and-cost-effectiveness-of-obeticholic-acid-for-the-treatment-of-primary-biliary-cholangitis
#8
Sumeyye Samur, Matthew Klebanoff, Reiner Banken, Daniel S Pratt, Rick Chapman, Daniel A Ollendorf, Anne M Loos, Kathleen Corey, Chin Hur, Jagpreet Chhatwal
: Primary biliary cholangitis (PBC) is a chronic, progressive autoimmune liver disease that mainly affects middle-aged women. Obeticholic acid (OCA), which was recently approved by the Food and Drug Administration for PBC treatment, has demonstrated positive effects on biochemical markers of liver function. Our objective was to evaluate the long-term clinical impact and cost-effectiveness of OCA as a second-line treatment for PBC in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA...
November 7, 2016: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/27905818/predictors-of-sleep-quality-among-young-adults-in-korea-gender-differences
#9
Ae Kyung Chang, Jinyi Choi
This study was performed to identify the factors influencing gender differences in sleep quality between men and women. A cross-sectional survey was conducted using a convenience sample of 300 young adults from three Korean universities. Participants were 20-40 years of age, used smartphones, and took no sleep medication. Participants completed questionnaires on sleep quality, exercise, stress, depression, and smart phone addiction. The predictors of sleep quality in men were coffee consumption, napping, depression, failure to engage in light exercise at least three times per week, being overweight, being in the potential smart phone addiction group, and being employed, which explained 30...
December 1, 2016: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/27904795/the-nine-test-screening-battery-normative-values-on-a-group-of-recreational-athletes
#10
Frida Flodström, Annette Heijne, Mark E Batt, Anna Frohm
BACKGROUND: A variety of risk factors predispose athletes to injury, such as impaired neuromuscular control, insufficient core stability, and muscular imbalances. The goal of assessing functional movement patterns is to detect imbalances and correct them with prevention strategies and thereby decrease injuries, and improve performance and quality of life. PURPOSE: The purpose of this study was to generate normative values for the 'Nine Test Screening Battery' (9TSB) in a group of recreational athletes...
December 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27902693/the-long-term-benefits-of-increased-aspirin-use-by-at-risk-americans-aged-50-and-older
#11
David B Agus, Étienne Gaudette, Dana P Goldman, Andrew Messali
BACKGROUND: The usefulness of aspirin to defend against cardiovascular disease in both primary and secondary settings is well recognized by the medical profession. Multiple studies also have found that daily aspirin significantly reduces cancer incidence and mortality. Despite these proven health benefits, aspirin use remains low among populations targeted by cardiovascular prevention guidelines. This article seeks to determine the long-term economic and population-health impact of broader use of aspirin by older Americans at higher risk for cardiovascular disease...
2016: PloS One
https://www.readbyqxmd.com/read/27901302/factors-associated-with-intentional-and-unintentional-non-adherence-to-adjuvant-endocrine-therapy-following-breast-cancer
#12
J Brett, D Fenlon, M Boulton, N J Hulbert-Williams, F M Walter, P Donnelly, B Lavery, A Morgan, C Morris, E Watson
Adherence to adjuvant endocrine therapy (AET) following breast cancer is known to be suboptimal despite its known efficacy in reducing recurrence and mortality. This study aims to investigate factors associated with non-adherence and inform the development of interventions to support women and promote adherence. A questionnaire survey to measure level of adherence, side effects experienced, beliefs about medicine, support received and socio-demographic details was sent to 292 women 2-4 years post breast cancer diagnosis...
November 30, 2016: European Journal of Cancer Care
https://www.readbyqxmd.com/read/27901247/anabolic-steroids-for-rehabilitation-after-hip-fracture-in-older-people
#13
Vaqas Farooqi, Maayken E L van den Berg, Ian D Cameron, Maria Crotty
BACKGROUND: Hip fracture occurs predominantly in older people, many of whom are frail and undernourished. After hip fracture surgery and rehabilitation, most patients experience a decline in mobility and function. Anabolic steroids, the synthetic derivatives of the male hormone testosterone, have been used in combination with exercise to improve muscle mass and strength in athletes. They may have similar effects in older people who are recovering from hip fracture. OBJECTIVES: To examine the effects (primarily in terms of functional outcome and adverse events) of anabolic steroids after surgical treatment of hip fracture in older people...
September 2016: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/27901223/metabolic-syndrome-and-quality-of-life-a-systematic-review
#14
Patrícia Pozas Saboya, Luiz Carlos Bodanese, Paulo Roberto Zimmermann, Andréia da Silva Gustavo, Caroline Melo Assumpção, Fernanda Londero
Objectives: to present currently available evidence to verify the association between metabolic syndrome and quality of life. Method: Cochrane Library, EMBASE, Medline and LILACS databases were studied for all studies investigating the association with metabolic syndrome and quality of life. Two blinded reviewers extracted data and one more was chosen in case of doubt. Results: a total of 30 studies were included, considering inclusion and exclusion criteria, which involved 62...
November 28, 2016: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/27901212/validation-of-the-brazilian-portuguese-version-of-the-premenstrual-symptoms-screening-tool-psst-and-association-of-psst-scores-with-health-related-quality-of-life
#15
Rachel de A Câmara, Cristiano A Köhler, Benicio N Frey, Thomas N Hyphantis, André F Carvalho
Objective: To develop and validate a Brazilian Portuguese version of the Premenstrual Symptoms Screening Tool (PSST), a questionnaire used for the screening of premenstrual syndrome (PMS) and of the most severe form of PMS, premenstrual dysphoric disorder (PMDD). The PSST also rates the impact of premenstrual symptoms on daily activities. Methods: A consecutive sample of 801 women aged ≥ 18 years completed the study protocol. The internal consistency, test-retest reliability, and content validity of the Brazilian PSST were determined...
November 24, 2016: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/27900864/-raloxifene-an-unexploited-possibility-of-prevention-and-treatment-of-postmenopausal-osteoporosis
#16
Jan Štěpán, Jan Rosa, Karel Pavelka
Long-term estrogen deficiency after menopause is responsible for different disorders, which not only make the quality of life in the older age worse but also are the major causes of womens mortality. It is especially the case for cardiovascular disease and osteoporosis. Aim of this review is to point at efficacy of raloxifene (a selective estrogen receptor modulator) in the long-term care of the women in their non-reproductive period of life, and namely in prevention and treatment of postmenopausal osteoporosis...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27900733/web-based-self-help-for-problematic-alcohol-use-a-large-naturalistic-study
#17
Magnus Johansson, Kristina Sinadinovic, Anders Hammarberg, Christopher Sundström, Ulric Hermansson, Sven Andreasson, Anne H Berman
PURPOSE: This observational study examined user characteristics, intervention use patterns, and variables associated with reductions in alcohol consumption for anonymous Internet help-seekers using a Web-based self-help program. METHOD: A Web-based cognitive behavioral therapy (CBT) program with eight modules delivered over 10 weeks was offered to participants with at least hazardous use of alcohol according to the Alcohol Use Disorders Identification Test (AUDIT) (n = 4165)...
November 29, 2016: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/27900196/muscle-function-is-associated-with-future-patient-reported-outcomes-in-young-adults-with-acl-injury
#18
Vala Flosadottir, Ewa M Roos, Eva Ageberg
BACKGROUND/AIM: Consequences of an anterior cruciate ligament (ACL) injury include worse patient-reported outcomes (PROs) and a decrease in activity level. Muscle function can be improved by targeted exercise. Our aims were to investigate cross-sectional and longitudinal associations among lower extremity muscle function and PROs after ACL injury. METHODS: Fifty-four participants (15 women, mean 30 years) with ACL injury or reconstruction, from the Knee Anterior Cruciate Ligament, Nonsurgical versus Surgical Treatment (KANON) trial (ISRCTN84752559), were assessed with hop performance, muscle power and postural orientation 3 years (SD 0...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27898991/nipple-and-areola-sparing-mastectomy-for-the-treatment-of-breast-cancer
#19
REVIEW
Bruna S Mota, Rachel Riera, Marcos Desidério Ricci, Jessica Barrett, Tiago B de Castria, Álvaro N Atallah, Jose Luiz B Bevilacqua
BACKGROUND: The efficacy and safety of nipple-sparing mastectomy and areola-sparing mastectomy for the treatment of breast cancer are still questionable. It is estimated that the local recurrence rates following nipple-sparing mastectomy are very similar to breast-conserving surgery followed by radiotherapy. OBJECTIVES: To assess the efficacy and safety of nipple-sparing mastectomy and areola-sparing mastectomy for the treatment of ductal carcinoma in situ and invasive breast cancer in women...
November 29, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27898669/postoperative-quality-of-life-and-sexual-function-in-premenopausal-women-undergoing-laparoscopic-myomectomy-for-symptomatic-fibroids-a-prospective-observational-cohort-study
#20
Julia Caroline Radosa, Christoph Georg Radosa, Russalina Mavrova, Stefan Wagenpfeil, Amr Hamza, Ralf Joukhadar, Sascha Baum, Maria Karsten, Ingolf Juhasz-Boess, Erich-Franz Solomayer, Marc Philipp Radosa
INTRODUCTION: Uterine leiomyomas are the most common benign gynecologic tumors. To date laparoscopy myomectomy is the gold standard for treatment of symptomatic fibroids in reproductive-aged women. Detailed counseling about the effects of this procedure on postoperative sexuality and quality of life is important in these patients. However, available data on these subjects are limited and contradictory. The aim of this study was to assess sexual function and quality of life in premenopausal women undergoing laparoscopic myomectomy for symptomatic uterine fibroids...
2016: PloS One
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