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https://www.readbyqxmd.com/read/28640938/obstructive-sleep-apnoea-and-polycystic-ovary-syndrome-a-comprehensive-review-of-clinical-interactions-and-underlying-pathophysiology
#1
REVIEW
Hassan Kahal, Ioannis Kyrou, Abd A Tahrani, Harpal S Randeva
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in women of reproductive age. PCOS is associated with multiple co-morbidities including, obesity, insulin resistance and type 2 diabetes, as well as mood disorders and impaired quality of life (QoL). Obstructive sleep apnoea (OSA) is also a common medical condition that is often undiagnosed, particularly in women. OSA is associated with a similar spectrum of comorbidities to that observed in PCOS, including manifestations of the metabolic syndrome and impaired QoL, whilst obesity frequently constitutes a common denominator in the pathophysiology of both OSA and PCOS...
June 22, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28640766/impact-of-recurrence-of-ovarian-cancer-on-quality-of-life-and-outlook-for-the-future
#2
Nicoletta Colombo, Domenica Lorusso, Paolo Scollo
OBJECTIVE: Ovarian cancer recurs in most patients, with a 5-year survival rate less than 30%. Quality of life is an increasingly important issue in patients with cancer, but there are limited data in women with recurrent ovarian cancer in this regard. MATERIALS AND METHODS: We used an ad hoc questionnaire to compare changes in health perceptions, burden of disease, and expectations for the future quality of life in women with and without recurrence of ovarian cancer...
July 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28637285/a-qualitative-study-of-the-impact-of-endometriosis-on-male-partners
#3
L Culley, C Law, N Hudson, H Mitchell, E Denny, N Raine-Fenning
STUDY QUESTION: What is the impact of endometrioses on male partners of women with the condition? SUMMARY ANSWER: Endometriosis significantly impacts men across several life domains and can negatively impact emotional well-being. WHAT IS KNOWN ALREADY: Endometriosis has been shown to negatively impact women's quality of life and may strain intimate relationships. Little is known about the impact on male partners. STUDY DESIGN, SIZE, DURATION: The ENDOPART study was a cross-sectional, qualitative study of 22 women with endometriosis and their male partners (n = 44) in the UK (2012-2013)...
June 15, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28637138/psychometric-properties-of-persian-version-of-the-caregiver-burden-scale-in-iranian-caregivers-of-patients-with-spinal-cord-injury
#4
Ata Farajzadeh, Malahat Akbarfahimi, Saman Maroufizadeh, Hamid Reza Rostami, Amir Hassan Kohan
PURPOSE: To investigate the psychometric properties of the Persian version of Caregiver Burden Scale (CBS) in caregivers of patients with spinal cord injury. METHODS: This is a cross-sectional study. After a forward-backward translation, the CBS was administered to 110 caregivers of patients with spinal cord injury (men = 60, women = 50). Factor structure was evaluated by confirmatory factor analysis. The Internal consistency and test-retest reliability of the CBS were examined using Cronbach's α and the intraclass correlation coefficient, respectively...
February 21, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28637133/efficacy-of-the-whole-body-vibration-for-pain-fatigue-and-quality-of-life-in-women-with-fibromyalgia-a-systematic-review
#5
Eduarda Moretti, Angélica Tenório, Laís Holanda, Adriana Campos, Andrea Lemos
PURPOSE: To determine the quality of evidence on the use of whole-body vibration (WBV) in controlling pain, fatigue and quality of life in women with fibromyalgia. METHODS: The search involved MEDLINE/PubMed, LILACS, CINAHL, CENTRAL and PEDro, without temporal or language restriction. The terms "fibromyalgia" and "whole-body vibration" were used. Trials (randomized or quasi-randomized) that compared a group of women with fibromyalgia who received WBV to a control group with no intervention were included...
February 10, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28635533/the-burden-of-endometriosis-symptoms-on-health-related-quality-of-life-in-women-in-the-united-states-a-cross-sectional-study
#6
Ahmed M Soliman, Karin S Coyne, Erica Zaiser, Jane Castelli-Haley, Mahesh J Fuldeore
INTRODUCTION: To examine the symptomatic burden of endometriosis on health-related quality of life (HRQL) in women in the United States (US). METHODS: A cross sectional web-based survey study was conducted among women using survey panels. The survey included study-specific questions and standardized HRQL questionnaires. Participants reviewed a list of endometriosis symptoms and selected all symptoms they had ever or were currently experiencing. For current symptoms, participants rated the severity and bothersomeness of each symptom...
February 21, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28635532/assessing-physical-symptoms-during-the-postpartum-period-reliability-and-validity-of-the-primary-health-questionnaire-somatic-symptom-subscale-phq-15
#7
Stephanie Wilkie, Ros Crawley, Susan Button, Alexandra Thornton, Susan Ayers
INTRODUCTION: This study aimed at establishing the reliability and validity of the primary health questionnaire (PHQ-15) somatic symptom severity subscale for postpartum women. METHODS: Women (N = 495) completed the PHQ-15 approximately 6 weeks postpartum during the baseline phase of a randomized controlled trial evaluating a writing intervention for postnatal health in England. Reliability was assessed using internal consistency statistics and convergent validity by comparing differences in self-reported physical health, health-related quality of life (QoL) and primary care usage by PHQ-15 symptom severity category...
February 20, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28635529/major-obstetric-hemorrhage-a-follow-up-survey-on-quality-of-life-of-women-and-their-partners
#8
Giel van Stralen, Laurine L M Ruijten, Ad A Kaptein, Ron Wolterbeek, Jos van Roosmalen
INTRODUCTION: A description is given of the quality of life (QOL) of women who were treated with peripartum embolization or hysterectomy for major obstetric hemorrhage (MOH). METHODS: Questionnaires assessing QOL, combined with questionnaires and drawings assessing illness perceptions, were used to compare women with MOH to reference groups provided by the questionnaires. RESULTS: Women who experienced MOH have similar scores on QOL questionnaires compared to reference groups...
February 9, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28633095/development-and-validation-of-the-polish-version-of-the-urogenital-distress-inventory-short-form-and-the-incontinence-impact-questionnaire-short-form
#9
Katarzyna A Skorupska, Pawel Miotla, Agnieszka Kubik-Komar, Pawel Skorupski, Tomasz Rechberger
OBJECTIVE: The Incontinence Impact Questionnaire (IIQ) measures the impact of urinary incontinence on activities, roles, and emotional states of women, whereas the Urogenital Distress Inventory (UDI) measures how troubling the symptoms are. The aim of this study was to develop and assess the effectiveness of a Polish version of the IIQ and UDI. STUDY DESIGN: The translation into Polish followed standardized procedures. 206 women aged between 31 and 83 years were included into the study...
June 15, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28631775/-innovations-in-the-treatment-of-ovarian-cancer-analysis-of-the-therapeutic-development-from-platinum-to-immunotherapy
#10
Gesuino Angius, Pierangela Sepe, Anselmo Papa, Silverio Tomao, Federica Tomao
Ovarian cancer is the seventh most common cancer in women. The therapeutic approach provides for an appropriate integration between surgery and chemotherapy. Surgery is an important step for diagnosis, staging and therapy, aiming at the complete cytoreduction of all macroscopic visible disease. At the moment, adjuvant and first-line chemotherapy has as a standard the carboplatin-paclitaxel combination. Further, the addition of bevacizumab in the advanced stage (IIIB-IV) is strongly recommended. Despite the initial effectiveness, however, 70-80% of patients develop relapsed disease within the first two years and require subsequent treatment lines that have palliative, rather than curative purposes and that seek to reach a chronic state for the disease...
June 2017: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/28631536/should-ovaries-be-removed-or-not-in-early-stage-cervical-adenocarcinoma-a-multicenter-retrospective-study-of-105-patients
#11
Jun Hu, Xiaobing Jiao, Zhifeng Yang, Heng Cui, Hongyan Guo, Yumei Wu, Lirong Zhu
The study population consisted of 105 patients with stage IA to IIB cervical adenocarcinoma (AC) who underwent radical hysterectomy and pelvic lymphadenectomy from three institutions between 1994 and 2015, including 86 patients with bilateral salpingo-oophorectomy (BSO) and 19 patients with ovarian preservation operation. Ovarian metastasis were diagnosed in 3 of 86 patients in BSO group with an incidence rate of 3.5% (3/86). Among the 19 patients with ovarian preservation, none developed an ovarian recurrence in the follow-up (2-71 months)...
June 20, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28631248/chilean-population-norms-derived-from-the-health-related-quality-of-life-sf-6d
#12
Miguel A Garcia-Gordillo, Daniel Collado-Mateo, Pedro R Olivares, José C Adsuar
OBJECTIVES: The Health-Related Quality of Life Short Form 6D (HRQoL SF-6D) provides utility values for health status. Utilities generated have a number of potentially valuable applications in economic evaluations and not only to ensure comparability between studies. Reference values can be useful to estimate the effect on patients' HRQoL as a result of interventions in the absence of control groups. Thus, the purpose of this study was to provide normative values in the SF-6D in relation to the Chilean population...
June 19, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/28631241/improving-self-management-of-type-2-diabetes-in-overweight-and-inactive-patients-through-an-educational-and-motivational-intervention-addressing-diet-and-physical-activity-a-prospective-study-in-naples-south-italy
#13
Francesca Gallé, Valeria Di Onofrio, Assunta Cirella, Mirella Di Dio, Alessandra Miele, Tiziana Spinosa, Giorgio Liguori
INTRODUCTION: Nutrition and physical activity are key elements in the prevention and management of type 2 diabetes. A community-based, multidisciplinary educational intervention aimed to improve quality of life and disease self-management in sedentary, overweight/obese type 2 diabetic patients was implemented in Naples, South Italy. METHODS: The 9-month intervention included a motivational program, a nutrition program, and an exercise program. Satisfaction, worry, and embarrassment regarding their condition, together with disease-related behaviors and propensity towards physical activity, were evaluated through a validated questionnaire before and after the intervention; health status perception was evaluated through the short-form 12 questionnaire...
June 19, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28629610/a-model-for-assessing-the-clinical-and-economic-benefits-of-bone-forming-agents-for-reducing-fractures-in-postmenopausal-women-at-high-near-term-risk-of-osteoporotic-fracture
#14
Claire E O'Hanlon, Anju Parthan, Morgan Kruse, Shannon Cartier, Bjorn Stollenwerk, Yawen Jiang, John P Caloyeras, Daria B Crittenden, Richard Barron
PURPOSE: The goal of this study was to assess and compare the potential clinical and economic value of emerging bone-forming agents using the only currently available agent, teriparatide, as a reference case in patients at high, near-term (imminent, 1- to 2-year) risk of osteoporotic fractures, extending to a lifetime horizon with sequenced antiresorptive agents for maintenance treatment. METHODS: Analyses were performed by using a Markov cohort model accounting for time-specific fracture protection effects of bone-forming agents followed by antiresorptive treatment with denosumab...
June 16, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28629468/improving-detection-and-initial-management-of-gestational-diabetes-through-the-primary-level-of-care-in-morocco-protocol-for-a-cluster-randomized-controlled-trial
#15
Bettina Utz, Bouchra Assarag, Amina Essolbi, Amina Barkat, Nawal El Ansari, Bouchra Fakhir, Alexandre Delamou, Vincent De Brouwere
BACKGROUND: Morocco is facing a growing prevalence of diabetes and according to latest figures of the World Health Organization, already 12.4% of the population are affected. A similar prevalence has been reported for gestational diabetes (GDM) and although it is not yet high on the national agenda, immediate and long-term complications threaten the health of mothers and future generations. A situational analysis on GDM conducted in 2015 revealed difficulties in access to screening and delays in receiving appropriate care...
June 19, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28629403/factors-influencing-professional-life-satisfaction-among-neurologists
#16
Stephanie M Teixeira-Poit, Michael T Halpern, Heather L Kane, Michael Keating, Murrey Olmsted
BACKGROUND: Predicted shortages in the supply of neurologists may limit patients' access to and quality of care for neurological disorders. Retaining neurologists already in practice provides one opportunity to support the overall supply of practicing neurologists. Understanding factors associated with professional life satisfaction (and dissatisfaction) and implementing policies to enhance satisfaction may encourage neurologists to remain in clinical practice. In this paper, we present results from the first study examining factors associated with professional life satisfaction among a large sample of U...
June 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28629394/validating-the-who-maternal-near-miss-tool-comparing-high-and-low-resource-settings
#17
Tom Witteveen, Hans Bezstarosti, Ilona de Koning, Ellen Nelissen, Kitty W Bloemenkamp, Jos van Roosmalen, Thomas van den Akker
BACKGROUND: WHO proposed the WHO Maternal Near Miss (MNM) tool, classifying women according to several (potentially) life-threatening conditions, to monitor and improve quality of obstetric care. The objective of this study is to analyse merged data of one high- and two low-resource settings where this tool was applied and test whether the tool may be suitable for comparing severe maternal outcome (SMO) between these settings. METHODS: Using three cohort studies that included SMO cases, during two-year time frames in the Netherlands, Tanzania and Malawi we reassessed all SMO cases (as defined by the original studies) with the WHO MNM tool (five disease-, four intervention- and seven organ dysfunction-based criteria)...
June 19, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28627297/a-bayesian-simulation-model-for-breast-cancer-screening-incidence-treatment-and-mortality
#18
Xuelin Huang, Yisheng Li, Juhee Song, Donald A Berry
BACKGROUND: The important but complicated research questions regarding the optimization of mammography screening for the detection of breast cancer are unable to be answered through any single trial or a simple meta-analysis of related trials. The Cancer Intervention and Surveillance Network (CISNET) breast groups provide answers using complex statistical models to simulate population dynamics. Among them, the MD Anderson Cancer Center (Model M) takes a unique approach by not making any assumptions on the natural history of breast cancer, such as the distribution of the indolent time before detection, but simulating only the observable part of a woman's disease and life...
June 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28627109/high-power-magnetotherapy-a-new-weapon-in-urinary-incontinence
#19
Maria Vadalà, Beniamino Palmieri, Andrea Malagoli, Carmen Laurino
OBJECTIVE: Urinary incontinence (UI) is one of the most common urinary system diseases that mostly affects women but also men. We evaluated the therapeutic efficacy of functional magnetic stimulation (FMS) as potential UI treatment with improvements in the pelvic floor musculature, urodynamic tests and quality of life. METHODS: A total of 20 UI patients (10 females and 10 men, mean age 64, 14 years), including 10 with stress UI, four with urgency UI and six with mixed UI, were treated with FMS (20 min/session) twice a week for 3 weeks...
June 18, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28625633/cost-effectiveness-of-implementing-computed-tomography-screening-for-lung-cancer-in-taiwan
#20
Szu-Chun Yang, Wu-Wei Lai, Chien-Chung Lin, Wu-Chou Su, Li-Jung Ku, Jing-Shiang Hwang, Jung-Der Wang
BACKGROUND: A screening program for lung cancer requires more empirical evidence. Based on the experience of the National Lung Screening Trial (NLST), we developed a method to adjust lead-time bias and quality-of-life changes for estimating the cost-effectiveness of implementing computed tomography (CT) screening in Taiwan. METHODS: The target population was high-risk (≥30 pack-years) smokers between 55 and 75 years of age. From a nation-wide, 13-year follow-up cohort, we estimated quality-adjusted life expectancy (QALE), loss-of-QALE, and lifetime healthcare expenditures per case of lung cancer stratified by pathology and stage...
June 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
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