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https://www.readbyqxmd.com/read/28747603/autoinflammatory-diseases-in-dermatology-ditra-and-camps
#1
Kazumitsu Sugiura
  Deficiency of interleukin thirty-six receptor antagonist (DITRA) and CARD14 mediated psoriasis (CAMPS) are autoinflammatory diseases in dermatology. The causative genes of DITRA and CMAPS have been identified recently. In this paper, IL36RN and CARD14, the causative gene for DITRA and CAMPS, respectively were explained. In addition, clinical features and therapies for generalized pustular psoriasis not associated with psoriasis vulgaris (GPP without PsV), and pityriasis rubra pilaris type V (PRP type V) were described...
2017: Nihon Rinshō Men'eki Gakkai Kaishi, Japanese Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28728872/oropharyngeal-lesions-in-pityriasis-rosea
#2
Giulia Ciccarese, Francesco Broccolo, Alfredo Rebora, Aurora Parodi, Francesco Drago
BACKGROUND: Pityriasis rosea (PR) is an exanthematous disease associated with the endogenous systemic reactivation of human herpesvirus-6 (HHV-6) and human herpesvirus-7 (HHV-7). Oropharyngeal lesions may be associated with the exanthema, but anecdotal evidence suggests that few dermatologists are aware of their occurrence. OBJECTIVE: Classifying oropharyngeal lesions in PR, establishing their prevalence, and assessing their possible association with different PR forms...
July 17, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28690516/eruptive-seborrheic-keratoses-restricted-to-plaque-patch-stage-mycosis-fungoides
#3
Eve Lebas, Pascale Quatresooz, Jorge E Arrese, Arjen F Nikkels
Eruptive seborrheic keratoses (ESK) are rare in dermatology. They are usually inflammatory in nature and may be encountered as Leser-Trélat sign. ESK may also be simultaneously observed with hepatic angiomas, chemotherapy, segmental neurofibromatosis, HIV or erythrodermic pityriasis rubra pilaris, psoriasis, and drug eruption. ESK may be transient and self-healing. Others recede after successful treatment of the underlying disease. In some instances, seborrheic keratoses may follow an isotopic response and remain strictly restricted to sites of previous eczema, photo-exposition or tattoos...
May 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/28685133/clinical-variants-of-pityriasis-rosea
#4
REVIEW
Francisco Urbina, Anupam Das, Emilio Sudy
Pityriasis rosea (PR) is a common erythemato-squamous dermatosis which almost always, is easily diagnosed. Mostly the disease presents in its classical form. However, clinical dermatology is all about variations and PR is not an exception. Variants of the disease in some cases may be troublesome to diagnose and confuse clinicians. Prompt diagnosis and treatment of the condition becomes necessary to avoid unnecessary investigations. We hereby review and illustrate atypical presentations of the disease, including diverse forms of location and morphology of the lesions, the course of the eruption, and its differential diagnoses...
June 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28670260/pityriasis-rosea-in-a-patient-with-retrovirus-infection-and-a-history-of-syphilis-and-positive-results-of-infection-with-hepatitis-a-virus-hepatitis-b-virus-and-hepatitis-c-virus
#5
Anna Neneman, Dominik Mikiel, Zygmunt Adamski, Monika Bowszyc-Dmochowska
No abstract text is available yet for this article.
June 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28584764/persistent-and-generalized-purpuric-lesions-in-an-adolescent-a-rare-atypical-form-of-pityriasis-rosea
#6
Funda Tamer, Evren Sarifakioglu, Ozge M Orenay, Umran Yildirim
No abstract text is available yet for this article.
May 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28561308/knowledge-perception-and-practice-of-patients-about-pityriasis-versicolor-in-kaduna-north-central-nigeria
#7
Husain Yahya
BACKGROUND: Although pityriasis versicolor (PV) is a common fungal infection of the skin affecting up to 50% of the population in the tropics, little is known about what patients know, believe, or feel about the condition. METHODS: In a cross-sectional questionnaire study of 608 consecutive patients attending the General Outpatient Department and Skin Clinic of a public hospital in Kaduna, Nigeria, self-report of PV, knowledge about its causes, treatments used by patients, and perception and feelings about the condition were assessed...
May 31, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28560294/psoriasis-vulgaris-with-fibrokeratoma-from-pityriasis-amiantacea
#8
Chihiro Shiiya, Yukiko Nomura, Yasuyuki Fujita, Chihiro Nakayama, Hiroshi Shimizu
No abstract text is available yet for this article.
May 2017: JAAD Case Reports
https://www.readbyqxmd.com/read/28451009/-pityriasis-versicolor-in-infants-unusual-clinical-presentation-and-role-of-corticosteroids-used-as-depigmenting-agent-for-cosmetic-purposes-in-the-mother
#9
Pauline Dioussé, Fatimata Ly, Mariama Bammo, Sarah Lizia, Thierno Abdoul Aziz Diallo, Haby Dione, Fatou Sarr, Ramatoulaye Diagne Gueye, Amadou Mactar Gueye, Mame Thierno Dieng, Bernard Marcel Diop, Mamadou Mourtalla Ka
We report two cases of Pityriasis versicolor (PV) in infants aged 12 and 18 months. The latter were brought to medical attention because of hypochromic and achromic, round macules involving the limbs and the face. Physical examination of their mothers showed voluntary depigmentation for cosmetic purposes due to the use of corticosteroids and hydroquinone, on average, over a 5-year period. The scotch tape test performed in one of the infants and his mother showed short filaments and clusters of spores. Treatment was based on ketoconazole...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28393697/targeting-malassezia-species-for-novel-synthetic-and-natural-antidandruff-agents
#10
Letizia Angiolella, Simone Carradori, Cristina Maccallini, Gustavo Giusiano, Claudiu T Supuran
Malassezia spp. are lipophilic yeasts not only present in the normal skin microflora, but also responsible of skin-related diseases (pityriasis versicolor, seborrheic/atopic dermatitis and dandruff) as well as systemic fungal infections in humans and animals. Their treatment and eradication are mainly based on old azole drugs, which are characterized by poor compliance, unpredictable clinical efficacy, emerging resistance and several side effects. These drawbacks have prompted the research toward novel synthetic and natural derivatives/nanomaterials targeting other pivotal enzymes/pathways such as carbonic anhydrase (MgCA) and lipases, alone or in combination, in order to improve the eradication rate of this fungus...
April 4, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28392639/demodex-mite-density-determinations-by-standardized-skin-surface-biopsy-and-direct-microscopic-examination-and-their-relations-with-clinical-types-and-distribution-patterns
#11
Chul Hyun Yun, Jeong Hwan Yun, Jin Ok Baek, Joo Young Roh, Jong Rok Lee
BACKGROUND: Demodicosis is a parasitic skin disease caused by Demodex mites, and the determination of mite density per square centimeter is important to diagnose demodicosis. Standardized skin surface biopsy (SSSB) and direct microscopic examination (DME) are commonly used to determine Demodex mites density (Dd). However, no study has previously compared these two methods with respect to clinical types and distribution patterns of demodicosis. OBJECTIVE: The aim of this study was to compare the value of SSSB and DME findings in reference to the clinical types and distribution patterns of demodicosis...
April 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28381607/antifungal-susceptibility-testing-of-malassezia-spp-with-an-optimized-colorimetric-broth-microdilution-method
#12
Cheryl Leong, Antonino Buttafuoco, Martin Glatz, Philipp P Bosshard
Malassezia is a genus of lipid-dependent yeasts. It is associated with common skin diseases such as pityriasis versicolor and atopic dermatitis and can cause systemic infections in immunocompromised individuals. Owing to the slow growth and lipid requirements of these fastidious yeasts, convenient and reliable antifungal drug susceptibility testing assays for Malassezia spp. are not widely available. Therefore, we optimized a broth microdilution assay for the testing of Malassezia that is based on the CLSI and EUCAST assays for Candida and other yeasts...
June 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28368874/efficacy-of-triaging-direct-immunofluorescence-in-intraepidermal-bullous-dermatoses
#13
Brian J Tjarks, Steven D Billings, Jennifer S Ko
BACKGROUND: Direct immunofluorescence (DIF) is considered pivotal in diagnosing autoimmune blistering diseases. Our goal was to examine the necessity of DIF in intraepidermal bullous cases, of which pemphigus vulgaris (PV) is the prototype. METHODS: Sixty-six cases from 2010 to 2014 submitted for DIF with an intraepidermal blistering disease listed in the differential diagnosis were reviewed by 2 board-certified dermatopathologists to see if they would order DIF based on routine histologic findings...
March 24, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28359163/pityriasis-rosea-like-eruption-induced-by-isotretinoin
#14
Gülhan Gürel, Sevinç Şahin, Emine Çölgeçen
Pityriasis rosea is a common, self-limited and inflammatory skin disease. The etiology is not clearly known. Viral agents, autoimmunity, psychogenic factors and drugs have all been suggested as risk factors. Isotretinoin is usually used in the treatment of resistant, nodulocytic acne. We present a case of pityriasis rosea-like eruption induced by isotretinoin. To our knowledge, this is the second clinical case of pityriasis rosea-like eruption induced by isotretinoin.
April 19, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/28346993/artemisia-sieberi-besser-essential-oil-and-treatment-of-fungal-infections
#15
REVIEW
Mohaddese Mahboubi
A. sieberi essential oil has been used for treatment of hardly curable infectious ulcers in Middle East Medicine and has been famous due to its wormicide effects. In this review, we evaluated the potency of A. sieberi essential oil in treatment of fungal infections. We searched in PubMed Central, Science direct, Wiley, Springer, SID, and accessible books, reports, thesis. There is a lot of mixed information on chemical compositions of A. sieberi essential oil, but most articles reported α, β-thujones as the main components of essential oils...
May 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28345391/a-retrospective-study-on-rapid-plasma-reagin-testing-in-patients-with-pityriasis-rosea
#16
Pierre Halteh, Shari R Lipner
Pityriasis rosea (PR) is an acute self-limited exanthem characterized by oval erythematous patches with scale and may be difficult to differentiate from secondary syphilis. A rapid plasma reagin (RPR) test can be used to rule in secondary syphilis with high sensitivity and specificity. A retrospective study was performed on patients at Weill Cornell Medicine, who were diagnosed with PR from 2000 to 2016 and also received RPR testing at the time of diagnosis. The objective was to assess the frequency of secondary syphilis when the initial clinical impression was PR...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28332161/real-time-pcr-identification-of-six-malassezia-species
#17
Amin Ilahi, Inès Hadrich, Sourour Neji, Houaida Trabelsi, Fattouma Makni, Ali Ayadi
Lipophilic yeast Malassezia species is widely found on the skin surface of humans and other animals. This fungus can cause pityriasis versicolor, Malassezia folliculitis, and seborrheic dermatitis. Still now, there is a problem with species identification of Malassezia with conventional methods. We developed a real-time polymerase chain reaction (PCR) assay with multiple hybridization probes for detecting M. globosa, M. furfur, M. restricta, M. sympodialis, M. slooffiae, and M. pachydermatis. The amplification curves and specific melting peaks of the probes hybridized with real-time PCR product were used for species identifications...
June 2017: Current Microbiology
https://www.readbyqxmd.com/read/28329497/unique-clinical-presentations-of-pityriasis-rosea-aphthous-ulcers-vesicles-and-inverse-distribution-of-lesions
#18
Naeha Gupta, Jacob O Levitt
Pityriasis Rosea (PR) is a common skin disorderencountered in daily practice. Although its etiologyhas not been established, there has been widespreadresearch into possibilities. The lack of its characteristicmanifestations, specifically the herald patch andtruncal involvement, can lead to pitfalls in diagnosis.Whereas other conditions in the differential diagnosisshould be considered, PR can at times also manifest inan atypical manner. We wish to illustrate three casesof PR including those that presented with aphthousulcers, vesicles, and an inverse pattern...
February 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28301045/beneficial-effect-of-ustekinumab-in-familial-pityriasis-rubra-pilaris-with-a-new-missense-mutation-in-card14
#19
S M Lwin, C-K Hsu, L Liu, H-Y Huang, N J Levell, J A McGrath
Pityriasis rubra pilaris (PRP) represents a group of rare chronic inflammatory skin disorders in which ~1 in 20 affected individuals show autosomal dominant inheritance. In such cases, there may be gain-of-function mutations in CARD14, encoding caspase recruitment domain-containing protein 14 (CARD14) that activates the non-canonical nuclear factor-kappa B (NF-κB) pathway, thereby promoting cutaneous inflammation. Here, we report a mother and son with PRP due to a new missense mutation in CARD14 and describe the beneficial clinical effects of ustekinumab, a monoclonal antibody against interleukins-12 and -23, in both subjects...
March 16, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28295164/autosomal-dominant-familial-generalized-pustular-psoriasis-caused-by-a-card14-mutation
#20
T Takeichi, A Kobayashi, E Ogawa, Y Okuno, S Kataoka, M Kono, K Sugiura, R Okuyama, M Akiyama
In 2012, gain-of-function mutations in CARD14, which encodes caspase recruitment domain family member 14, were identified as the cause of familial psoriasis vulgaris (PV) and familial pityriasis rubra pilaris (PRP).(1,2) We and another group reported that CARD14 variants are associated with generalized pustular psoriasis (GPP) and palmoplantar pustular psoriasis (PPP).(3-5) The other reports mentioned that CARD14 mutations in individuals with GPP and erythrodermic PRP. (4,6) Very recently, we described PRP type V as an autoinflammatory disease caused by CARD14 mutations...
March 10, 2017: British Journal of Dermatology
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