keyword
MENU ▼
Read by QxMD icon Read
search

Molecular vitamin nutrient

keyword
https://www.readbyqxmd.com/read/29767119/recent-advances-in-sturgeon-nutrition
#1
REVIEW
Silas S O Hung
Sturgeons are fish species of biological and economical importance, and most of them are endangered, vulnerable or rare because of their large size, late sexual maturity, long period between spawning, and longevity. These unique biological characteristics make them highly susceptible to overfishing, degradation of habitat and spawning ground, and contamination of water and sediments by pollutants. The objective of the current review is not to exhaustively include all studies on sturgeon nutrient requirements and utilizations conducted under laboratory conditions, but to critique some studies and update previous reviews...
September 2017: Animal nutrition
https://www.readbyqxmd.com/read/29741189/investigation-of-the-effects-of-mechanical-treatments-on-cellular-structure-integrity-and-vitamin-c-extractability-of-broccoli-brassica-oleracea-l-var-italica-by-lf-nmr
#2
Jinxin Yang, Xin Jin, Xiao Dong Chen
Extraction of nutrients from plants is an important unit operation in the food and biological industries. The target nutrient is usually spatially distributed throughout the plant tissue. The intact cell wall and adhering membranes are the main resistances to molecular diffusion. Therefore, disintegration of the intact structure, which in turn increases the permeability of adhering membranes, can significantly improve the nutrient extraction yield and efficiency. In this study, different physical treatments (homogenization, high pressure homogenization, and ball mill grinding) were applied to investigate their effects on the tissue microstructure and the release of vitamin C...
May 9, 2018: Food & Function
https://www.readbyqxmd.com/read/29728792/carbohydrate-reserves-and-seed-development-an-overview
#3
REVIEW
Manuel Aguirre, Edward Kiegle, Giulia Leo, Ignacio Ezquer
Seeds are one of the most important food sources, providing humans and animals with essential nutrients. These nutrients include carbohydrates, lipids, proteins, vitamins and minerals. Carbohydrates are one of the main energy sources for both plant and animal cells and play a fundamental role in seed development, human nutrition and the food industry. Many studies have focused on the molecular pathways that control carbohydrate flow during seed development in monocot and dicot species. For this reason, an overview of seed biodiversity focused on the multiple metabolic and physiological mechanisms that govern seed carbohydrate storage function in the plant kingdom is required...
May 4, 2018: Plant Reproduction
https://www.readbyqxmd.com/read/29697537/bariatric-surgery-and-gene-expression-in-the-gut
#4
Priscila Sala, M L Corrêa-Giannella, Dan L Waitzberg
PURPOSE OF REVIEW: The current review provides an overview of recent literature on new findings related to bariatric surgery and gut gene expression. RECENT FINDINGS: Bariatric surgery modulates the expression of intestinal genes. Experimental and clinical investigations have demonstrated the association of gut rearrangement with changes in intestinal expression of genes related to glucose metabolism. Recent data suggest that bariatric surgery also affects expression of genes belonging to other pathways, including nutrient transporters and metabolism of vitamin B12, decreasing pathway-encoding genes that may contribute to vitamin B12 deficiency in the postoperative period...
April 24, 2018: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/29520716/rhythmic-diurnal-synthesis-and-signaling-of-retinoic-acid-in-the-rat-pineal-gland-and-its-action-to-rapidly-downregulate-erk-phosphorylation
#5
Anna Ashton, Patrick N Stoney, Jemma Ransom, Peter McCaffery
Vitamin A is important for the circadian timing system; deficiency disrupts daily rhythms in activity and clock gene expression, and reduces the nocturnal peak in melatonin in the pineal gland. However, it is currently unknown how these effects are mediated. Vitamin A primarily acts via the active metabolite, retinoic acid (RA), a transcriptional regulator with emerging non-genomic activities. We investigated whether RA is subject to diurnal variation in synthesis and signaling in the rat pineal gland. Its involvement in two key molecular rhythms in this gland was also examined: kinase activation and induction of Aanat, which encodes the rhythm-generating melatonin synthetic enzyme...
March 8, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29499643/identification-of-placental-nutrient-transporters-associated-with-intrauterine-growth-restriction-and-pre-eclampsia
#6
Xiao Huang, Pascale Anderle, Lu Hostettler, Marc U Baumann, Daniel V Surbek, Edgar C Ontsouka, Christiane Albrecht
BACKGROUND: Gestational disorders such as intrauterine growth restriction (IUGR) and pre-eclampsia (PE) are main causes of poor perinatal outcomes worldwide. Both diseases are related with impaired materno-fetal nutrient transfer, but the crucial transport mechanisms underlying IUGR and PE are not fully elucidated. In this study, we aimed to identify membrane transporters highly associated with transplacental nutrient deficiencies in IUGR/PE. RESULTS: In silico analyses on the identification of differentially expressed nutrient transporters were conducted using seven eligible microarray datasets (from Gene Expression Omnibus), encompassing control and IUGR/PE placental samples...
March 2, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29477224/dietary-vitamin-c-in-human-health
#7
REVIEW
Matthew Granger, Peter Eck
Vitamin C is essential to prevent scurvy in humans and is implicated in the primary prevention of common and complex diseases such as coronary heart disease, stroke, and cancer. This chapter reviews the latest knowledge about dietary vitamin C in human health with an emphasis on studies of the molecular mechanisms of vitamin C maintenance as well as gene-nutrient interactions modifying these relationships. Epidemiological evidence indicates 5% prevalence for vitamin C deficiency and 13% prevalence for suboptimal status even in industrialized countries...
2018: Advances in Food and Nutrition Research
https://www.readbyqxmd.com/read/29445184/parental-micronutrient-deficiency-distorts-liver-dna-methylation-and-expression-of-lipid-genes-associated-with-a-fatty-liver-like-phenotype-in-offspring
#8
Kaja H Skjærven, Lars Martin Jakt, Jorge M O Fernandes, John Arne Dahl, Anne-Catrin Adam, Johanna Klughammer, Christoph Bock, Marit Espe
Micronutrient status of parents can affect long term health of their progeny. Around 2 billion humans are affected by chronic micronutrient deficiency. In this study we use zebrafish as a model system to examine morphological, molecular and epigenetic changes in mature offspring of parents that experienced a one-carbon (1-C) micronutrient deficiency. Zebrafish were fed a diet sufficient, or marginally deficient in 1-C nutrients (folate, vitamin B12, vitamin B6, methionine, choline), and then mated. Offspring livers underwent histological examination, RNA sequencing and genome-wide DNA methylation analysis...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29401702/bioactive-dietary-vdr-ligands-regulate-genes-encoding-biomarkers-of-skin-repair-that-are-associated-with-risk-for-psoriasis
#9
Amitis Karrys, Islam Rady, Roxane-Cherille N Chamcheu, Marya S Sabir, Sanchita Mallick, Jean Christopher Chamcheu, Peter W Jurutka, Mark R Haussler, G Kerr Whitfield
Treatment with 1,25-dihydroxyvitamin D₃ (1,25D) improves psoriasis symptoms, possibly by inducing the expression of late cornified envelope ( LCE )3 genes involved in skin repair. In psoriasis patients, the majority of whom harbor genomic deletion of LCE3B and LCE3C ( LCE3C_LCE3B-del ), we propose that certain dietary analogues of 1,25D activate the expression of residual LCE3A/LCE3D/LCE3E genes to compensate for the loss of LCE3B / LCE3C in the deletant genotype. Herein, human keratinocytes (HEKn) homozygous for LCE3C_LCE3B-del were treated with docosahexaenoic acid (DHA) and curcumin, two low-affinity, nutrient ligands for the vitamin D receptor (VDR)...
February 4, 2018: Nutrients
https://www.readbyqxmd.com/read/29382185/genetic-variations-in-sweet-taste-receptor-gene-are-related-to-chocolate-powder-and-dietary-fiber-intake-in-obese-children-and-adolescents
#10
Marina B Pioltine, Maria Edna de Melo, Aritânia S Santos, Alisson D Machado, Ariana E Fernandes, Clarissa T Fujiwara, Cintia Cercato, Marcio C Mancini
Childhood obesity is a major public health problem. It has a direct impact on the quality of life of children and adolescents, as well as on their future risk of developing chronic diseases. Dietary patterns rich in fats and sugars and lacking dietary fibers, vitamins, and minerals, as well as lack of physical exercise have been associated with the rise of obesity prevalence. However, factors that contribute to the preference for foods rich in these nutrients are not well established. Taste is recognized as an important predictor of food choices, and polymorphisms in taste-related genes may explain the variability of taste preference and food intake...
January 29, 2018: Journal of Personalized Medicine
https://www.readbyqxmd.com/read/29238546/receptor-uptake-arrays-for-vitamin-b-12-siderophores-and-glycans-shape-bacterial-communities
#11
REVIEW
Steven A Frank
Molecular variants of vitamin B12 , siderophores, and glycans occur. To take up variant forms, bacteria may express an array of receptors. The gut microbe Bacteroides thetaiotaomicron has three different receptors to take up variants of vitamin B12 and 88 receptors to take up various glycans. The design of receptor arrays reflects key processes that shape cellular evolution. Competition may focus each species on a subset of the available nutrient diversity. Some gut bacteria can take up only a narrow range of carbohydrates, whereas species such as B...
December 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29224093/sex-effects-at-the-ramparts-nutrient-and-microbe-mediated-regulation-of-the-immune-metabolic-interface
#12
Nyrie Israelian, Jayne S Danska
The relationships between dietary compounds, derivative metabolites, and host metabolism and immunity are controlled by diverse molecular mechanisms. Essential contributions to these dynamics come from the community of microbes (the microbiome) inhabiting the human digestive tract. The composition and function of the microbiome are shaped by available nutrients, and reciprocally, these organisms produce an as yet poorly defined repertoire of molecules that communicate with the epithelial barrier and the mucosal immune system...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29202036/free-radicals-and-advanced-chemistries-involved-in-cell-membrane-organization-influence-oxygen-diffusion-and-pathology-treatment
#13
Richard C Petersen
A breakthrough has been discovered in pathology chemistry related to increasing molecular structure that can interfere with oxygen diffusion through cell membranes. Free radicals can crosslink unsaturated low-viscosity fatty acid oils by chain-growth polymerization into more viscous liquids and even solids. Free radicals are released by mitochondria in response to intermittent hypoxia that can increase membrane molecular organization to reduce fluidity and oxygen diffusion in a possible continuing vicious cycle toward pathological disease...
2017: AIMS Biophysics
https://www.readbyqxmd.com/read/29178045/considering-choline-as-methionine-precursor-lipoproteins-transporter-hepatic-promoter-and-antioxidant-agent-in-dairy-cows
#14
REVIEW
Imtiaz Hussain Raja Abbasi, Farzana Abbasi, Rab N Soomro, Mohamed E Abd El-Hack, Mervat A Abdel-Latif, Wen Li, Ren Hao, Feifei Sun, Bello M Bodinga, Khawar Hayat, Junhu Yao, Yangchun Cao
During the transition period, fatty liver syndrome may be caused in cows undergo negative energy balance, ketosis or hypocalcemia, retained placenta or mastitis problems. During the transition stage, movement of non-esterified fatty acids (NEFA) increases into blood which declines the hepatic metabolism or reproduction and consequently, lactation performance of dairy cows deteriorates. Most of studies documented that, choline is an essential nutrient which plays a key role to decrease fatty liver, NEFA proportion, improve synthesis of phosphatidylcholine, maintain lactation or physiological function and work as anti-oxidant in the transition period of dairy cows...
November 25, 2017: AMB Express
https://www.readbyqxmd.com/read/29141977/vitamins-associated-with-brain-aging-mild-cognitive-impairment-and-alzheimer-disease-biomarkers-epidemiological-and-experimental-evidence-plausible-mechanisms-and-knowledge-gaps
#15
REVIEW
Michael Fenech
The key to preventing brain aging, mild cognitive impairment (MCI), and Alzheimer disease (AD) via vitamin intake is first to understand molecular mechanisms, then to deduce relevant biomarkers, and subsequently to test the level of evidence for the impact of vitamins in the relevant pathways and their modulation of dementia risk. This narrative review infers information on mechanisms from gene and metabolic defects associated with MCI and AD, and assesses the role of vitamins using recent results from animal and human studies...
November 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/29108031/beef-steers-with-average-dry-matter-intake-and-divergent-average-daily-gain-have-altered-gene-expression-in-the-jejunum
#16
A P Foote, B N Keel, C M Zarek, A K Lindholm-Perry
The objective of this study was to determine the association of differentially expressed genes (DEG) in the jejunum of steers with average DMI and high or low ADG. Feed intake and growth were measured in a cohort of 144 commercial Angus steers consuming a finishing diet containing (on a DM basis) 67.8% dry-rolled corn, 20% wet distillers grains with solubles, 8% alfalfa hay, and 4.2% vitamin/mineral supplement. From the cohort, a subset of steers with DMI within ±0.32 SD of the mean for DMI and the greatest (high) and least (low) ADG were chosen for slaughter and jejunum mucosa collection ( = 8 for each group)...
October 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/29070548/excess-iron-considerations-related-to-development-and-early-growth
#17
REVIEW
Marianne Wessling-Resnick
What effects might arise from early life exposures to high iron? This review considers the specific effects of high iron on the brain, stem cells, and the process of erythropoiesis and identifies gaps in our knowledge of what molecular damage may be incurred by oxidative stress that is imparted by high iron status in early life. Specific areas to enhance research on this topic include the following: longitudinal behavioral studies of children to test associations between iron exposures and mood, emotion, cognition, and memory; animal studies to determine epigenetic changes that reprogram brain development and metabolic changes in early life that could be followed through the life course; and the establishment of human epigenetic markers of iron exposures and oxidative stress that could be monitored for early origins of adult chronic diseases...
December 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29058531/biophysical-and-computational-comparison-on-the-binding-affinity-of-three-important-nutrients-to-%C3%AE-lactoglobulin-folic-acid-ascorbic-acid-and-vitamin-k3
#18
Somaye Shahraki, Ali Heydari, Maryam Saeidifar, Masoumeh Gomroki
Small globular protein, β-lactoglobulin (βLG), which has significant affinity toward many drugs, is the most abundant whey protein in milk. In this study, the interaction of βLG with three important nutrients, ascorbic acid (ASC), folic acid (FOL) and vitamin K3 (VK3) was investigated by spectroscopic methods (UV-visible and fluorescence) along with molecular docking technique. The results of fluorescence measurements showed that studied nutrients strongly quenched βLG fluorescence in static (FOL and ACS) or static-dynamic combined quenching (VK3) mode...
October 23, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/29037490/alzheimer-s-disease-pathogenesis-is-there-a-role-for-folate
#19
REVIEW
Natassia Robinson, Peter Grabowski, Ishtiaq Rehman
Epigenetic modifications, including changes in DNA methylation, have been implicated in a wide range of diseases including neurological diseases such as Alzheimer's. The role of dietary folate in providing methyl groups required for maintenance and modulation of DNA methylation makes it a nutrient of interest in Alzheimer's. Late onset Alzheimer's disease is the most common form of dementia and at present its aetiology is largely undetermined. From epidemiological studies, the interactions between folate, B-vitamins and homocysteine as well as the long latency period has led to difficulties in interpretation of the data, thus current evidence exploring the role of dietary folate in Alzheimer's is contradictory and unresolved...
October 13, 2017: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/28986235/alpha-synuclein-epigenetics-mitochondria-metabolism-calcium-traffic-circadian-dysfunction-in-parkinson-s-disease-an-integrated-strategy-for-management
#20
REVIEW
Oliver T Phillipson
The motor deficits which characterise the sporadic form of Parkinson's disease arise from age-related loss of a subset of dopamine neurons in the substantia nigra. Although motor symptoms respond to dopamine replacement therapies, the underlying disease process remains. This review details some features of the progressive molecular pathology and proposes deployment of a combination of nutrients: R-lipoic acid, acetyl-l-carnitine, ubiquinol, melatonin (or receptor agonists) and vitamin D3, with the collective potential to slow progression of these features...
November 2017: Ageing Research Reviews
keyword
keyword
96768
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"