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fish oil and oxidation

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https://www.readbyqxmd.com/read/28321544/physiological-activities-of-the-combination-of-fish-oil-and-%C3%AE-lipoic-acid-affecting-hepatic-lipogenesis-and-parameters-related-to-oxidative-stress-in-rats
#1
Takashi Ide
PURPOSE: We studied the combined effect of fish oil and α-lipoic acid on hepatic lipogenesis and fatty acid oxidation and parameters of oxidative stress in rats fed lipogenic diets high in sucrose. A control diet contained a saturated fat (palm oil) that gives high rate of hepatic lipogenesis. METHODS: Male Sprague-Dawley rats were fed diets supplemented with 0 or 2.5 g/kg α-lipoic acid and containing 0, 20, or 100 g/kg fish oil, for 21 days. RESULTS: α-Lipoic acid significantly reduced food intake during 0-8 days but not the later period of the experiment...
March 20, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28317774/development-of-an-up-grading-process-to-produce-mlm-structured-lipids-from-sardine-discards
#2
R Morales-Medina, M Munio, A Guadix, E M Guadix
The aim of the work was to produce MLM structured lipids with caprylic acid (M) as medium chain fatty acid located at the external bonds of the glycerol backbone and concentrated polyunsaturated fatty acids (L) from sardine discards (Sardine pilchardus) in the central bond of the glycerol. To that end, the following steps were conducted: (i) fish oil extraction, (ii) Omega-3 free fatty acids (FFA) concentration (low temperature winterization), (iii) two-steps enzymatic esterification and (iv) triacylglycerols (TAG) purification (liquid column chromatography)...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28291869/neuroprotective-effects-of-omega-3-polyunsaturated-fatty-acids-in-a-rat-model-of-anterior-ischemic-optic-neuropathy
#3
Tassos Georgiou, Yao-Tseng Wen, Chung-Hsing Chang, Panagiotis Kolovos, Maria Kalogerou, Ekatherine Prokopiou, Anastasia Neokleous, Chin-Te Huang, Rong-Kung Tsai
Purpose: The purpose of this study was to investigate the therapeutic effect of omega-3 polyunsaturated fatty acid (ω-3 PUFA) administration in a rat model of anterior ischemic optic neuropathy (rAION). Methods: The level of blood arachidonic acid/eicosapentaenoic acid (AA/EPA) was measured to determine the suggested dosage. The rAION-induced rats were administered fish oil (1 g/day EPA) or phosphate-buffered saline (PBS) by daily gavage for 10 consecutive days to evaluate the neuroprotective effects...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28284945/fish-oil-prevents-rodent-anxious-states-comorbid-with-diabetes-a-putative-involvement-of-nitric-oxide-modulation
#4
Isadora Pozzetti Siba, Mariza Bortolanza, Maria Aparecida Barbato Frazão Vital, Roberto Andreatini, Joice Maria da Cunha, Elaine Aparecida Del Bel, Janaína Menezes Zanoveli
There is an urgent need to understand the pathophysiological mechanisms related to anxiety associated with diabetes, seeking more effective alternative treatments to treat it. For that, the effect of a preventive and prolonged treatment with fish oil (FO), a source of omega-3 polyunsaturated fatty acid, was tested in streptozotocin-diabetic (DBT) rats submitted to the anxiety tests. Additionally, an immunohistochemistry for neuronal NO synthase (nNOS) was performed in brain areas related to anxiety, such as lateral amygdala (AMY), hippocampus (HIP) and dorsolateral periaqueductal gray (dlPAG)...
March 8, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28260647/a-lipidomic-study-on-the-regulation-of-inflammation-and-oxidative-stress-targeted-by-marine-%C3%AF-3-pufa-and-polyphenols-in-high-fat-high-sucrose-diets
#5
Gabriel Dasilva, Manuel Pazos, Eduardo García-Egido, José M Gallardo, Sara Ramos-Romero, Josep Lluís Torres, Marta Romeu, María-Rosa Nogués, Isabel Medina
The ability of polyphenols to ameliorate potential oxidative damage of ω-3 PUFAs when they are consumed together and then, to enhance their potentially individual effects on metabolic health is discussed through the modulation of fatty acids profiling and the production of lipid mediators. For that, the effects of the combined consumption of fish oils and grape seed procyanidins on the inflammatory response and redox unbalance triggered by high-fat high-sucrose (HFHS) diets were studied in an animal model of Wistar rats...
February 21, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28257923/rna-seq-and-deg-based-comparison-of-developmental-toxicity-in-fish-embryos-of-two-species-exposed-to-iranian-heavy-crude-oil
#6
Jee-Hyun Jung, Junsu Ko, Eun-Hee Lee, Kwang-Min Choi, Moonkoo Kim, Un Hyuk Yim, Jae-Seong Lee, Won Joon Shim
To determine and compare the toxic effects of Iranian heavy crude oil (IHCO) on the embryonic development of two fish species, we examined transcriptome profiles using RNA-seq. The assembled contigs were 66,070 unigenes in olive flounder embryos and 76,498 unigenes in spotted seabass embryos. In the differential gene expression (DEG) profiles, olive flounder embryos showed different up- and down-regulated patterns than spotted seabass embryos in response to fresh IHCO (FIHCO) and weathered IHCO (WIHCO). In this work, we categorized DEG profiles into six pathways: ribosome, oxidative phosphorylation, Parkinson's disease, Alzheimer's disease, Huntington's disease, and cardiac muscle contraction, validating the expression patterns of 13 DEGs using real-time quantitative RT-PCR...
February 28, 2017: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/28245885/olive-oil-bioactive-compounds-increase-body-weight-and-improve-gut-health-and-integrity-in-gilthead-sea-bream-sparus-aurata
#7
Enric Gisbert, Karl B Andree, José C Quintela, Josep A Calduch-Giner, Ignacio R Ipharraguerre, Jaume Pérez-Sánchez
An olive oil bioactive extract (OBE) rich in bioactive compounds like polyphenols, triterpenic acids, long-chain fatty alcohols, unsaturated hydrocarbons, tocopherols and sterols was tested (0, 0·08, 0·17, 0·42 and 0·73 % OBE) in diets fed to sea bream (Sparus aurata) (initial weight: 5·4 (sd 1·2) g) during a 90-d trial (four replicates). Fish fed diets containing 0·17 and 0·42 % OBE were 5 % heavier (61·1 (sd 1·6) and 60·3 (sd 1·1) g, respectively) than those of the control group (57·0 (sd 0·7) g), although feed conversion ratio and specific feed intake did not vary...
March 1, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28244792/effects-unrelated-to-anti-inflammation-of-lipid-emulsions-containing-fish-oil-in-parenteral-nutrition-for-adult-patients
#8
Javier Mateu de Antonio, Marta Florit-Sureda
Several reviews and meta-analyses on modulated inflammatory and immunologic responses after the administration of omega-3 polyunsaturated fatty acids (PUFAs) in different diseases and conditions have been published. However, omega-3 PUFAs exert several other actions which are not directly related to immunologic or inflammatory responses. The aim of this paper was to review the effects which are not directly related to immunologic and inflammatory responses of intravenous lipid emulsions (IVLEs) containing fish oil (FO) in parenteral nutrition (PN) for adult patients...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28242900/effect-of-the-partial-replacement-of-pork-backfat-by-microencapsulated-fish-oil-or-mixed-fish-and-olive-oil-on-the-quality-of-frankfurter-type-sausage
#9
Rubén Domínguez, Mirian Pateiro, Rubén Agregán, José M Lorenzo
Frankfurter sausages were reformulated to produce better lipid compositions by replacing the pork backfat by healthy oils. Sausages in, three different batches were manufactured: control (CO) with 100% of pork backfat, and modified sausages where the pork backfat was replaced with 50% by microencapsulated fish oil (ME) and by unencapsulated olive and fish oil mixture (OM). The ME treatments showed the lowest pH, fat and energy values and the highest protein and carbohydrates levels. The fat replacement by oils significantly (P < 0...
January 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28241421/age-related-loss-in-bone-mineral-density-of-rats-fed-lifelong-on-a-fish-oil-based-diet-is-avoided-by-coenzyme-q10-addition
#10
Alfonso Varela-López, Julio J Ochoa, José M Llamas-Elvira, Magdalena López-Frías, Elena Planells, MCarmen Ramirez-Tortosa, Cesar L Ramirez-Tortosa, Francesca Giampieri, Maurizio Battino, José L Quiles
During aging, bone mass declines increasing osteoporosis and fracture risks. Oxidative stress has been related to this bone loss, making dietary compounds with antioxidant properties a promising weapon. Male Wistar rats were maintained for 6 or 24 months on diets with fish oil as unique fat source, supplemented or not with coenzyme Q10 (CoQ10), to evaluate the potential of adding this molecule to the n-3 polyunsaturated fatty acid (n-3 PUFA)-based diet for bone mineral density (BMD) preservation. BMD was evaluated in the femur...
February 22, 2017: Nutrients
https://www.readbyqxmd.com/read/28230995/synthesis-of-high-quality-biodiesel-using-feedstock-and-catalyst-derived-from-fish-wastes
#11
Devarapaga Madhu, Rajan Arora, Shalini Sahani, Veena Singh, Yogesh Chandra Sharma
A low-cost and high-purity calcium oxide (CaO) was prepared from waste crab shells, which were extracted from the dead crabs, was used as an efficient solid base catalyst in the synthesis of biodiesel. Raw fish oil was extracted from waste parts of fish through mechanical expeller followed by solvent extraction. Physical as well as chemical properties of raw fish oil were studied, and its free fatty acid composition was analyzed with GC-MS. Stable and high-purity CaO was obtained when the material was calcined at 800 °C for 4 h...
March 2, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28221817/neuroprotective-effect-of-omega-3-polyunsaturated-fatty-acids-in-the-6-ohda-model-of-parkinson-s-disease-is-mediated-by-a-reduction-of-inducible-nitric-oxide-synthase
#12
Marco Aurélio Mori, Ana Marcia Delattre, Bruno Carabelli, Claudia Pudell, Mariza Bortolanza, Pedro Vinícius Staziaki, Jesuí Vergilio Visentainer, Paula Fernandes Montanher, Elaine A Del Bel, Anete Curte Ferraz
OBJECTIVE: Parkinson's disease (PD) is characterized by deterioration of the nigrostriatal system and associated with chronic neuroinflammation. Glial activation has been associated with regulating the survival of dopaminergic neurons and is thought to contribute to PD through the release of proinflammatory and neurotoxic factors, such as reactive nitric oxide (NO) that triggers or exacerbates neurodegeneration in PD. Polyunsaturated fatty acids (PUFAs) exert protective effects, including antiinflammatory, antiapoptotic, and antioxidant activity, and may be promising for delaying or preventing PD by attenuating neuroinflammation and preserving dopaminergic neurons...
February 21, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28212448/hepatic-transcriptome-analysis-and-identification-of-differentially-expressed-genes-response-to-dietary-oxidized-fish-oil-in-loach-misgurnus-anguillicaudatus
#13
Yin Zhang, Yang Li, Xiao Liang, Xiaojuan Cao, Longfei Huang, Jie Yan, Yanxing Wei, Jian Gao
RNA sequencing and short-read assembly were utilized to produce a transcriptome of livers from loaches (Misgurnus anguillicaudatus) fed with three different diets respectively containing fresh fish oil (FO group), medium oxidized fish oil (MO group) and high oxidized fish oil (HO group). A total of 60,663 unigenes were obtained in this study, with mean length 848.74 bp. 50,814, 49,584 and 49,814 unigenes were respectively obtained from FO, MO and HO groups. There were 2,343 differentially expressed genes between FO and MO, with 855 down- and 1,488 up-regulated genes in the MO group...
2017: PloS One
https://www.readbyqxmd.com/read/28212390/lack-of-effects-of-fish-oil-supplementation-for-12-weeks-on-resting-metabolic-rate-and-substrate-oxidation-in-healthy-young-men-a-randomized-controlled-trial
#14
Sebastian Jannas-Vela, Kaitlin Roke, Stephanie Boville, David M Mutch, Lawrence L Spriet
Fish oil (FO) has been shown to have beneficial effects in the body via incorporation into the membranes of many tissues. It has been proposed that omega-3 fatty acids in FO may increase whole body resting metabolic rate (RMR) and fatty acid (FA) oxidation in human subjects, but the results to date are equivocal. The purpose of this study was to investigate the effects of a 12 week FO supplementation period on RMR and substrate oxidation, in comparison to an olive oil (OO) control group, in young healthy males (n = 26; 22...
2017: PloS One
https://www.readbyqxmd.com/read/28189115/n-3-polyunsaturated-fatty-acids-alleviate-high-glucose-mediated-dysfunction-of-endothelial-progenitor-cells-and-prevent-ischemic-injuries-both-in-vitro-and-in-vivo
#15
Shao-Chih Chiu, Che-Yi Chao, En-Pei Isabel Chiang, Jia-Ning Syu, Raymond L Rodriguez, Feng-Yao Tang
Hyperglycemia is associated with a reduced number of endothelial progenitor cells (EPCs) that impairs vascular function. Circulating EPCs play important roles in postnatal neovasculogenesis and the prevention of ischemic injury. Frequent consumption of fish oil (FO) that is abundant with eicosapentaenoic acid (EPA)/docosahexaenoic acid (DHA) is reportedly associated with an alleviation of diabetic complications and a lowered incidence of cardiovascular disease. The aim of this study was to examine whether N-3 polyunsaturated fatty acids such as EPA and DHA would reverse the high glucose-mediated dysfunction of EPCs in vitro and thereby prevent the ischemic injury that occurs under the hyperglycemic conditions in Type 2 diabetes (T2D) db(-/-) mice...
January 28, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28183738/reply-to-letter-to-the-editor-determining-the-potential-effects-of-oxidized-fish-oils-in-pregnant-women-requires-a-more-systematic-approach
#16
Benjamin B Albert, José G B Derraik, Mark H Vickers, Manohar L Garg, David Cameron-Smith, Paul L Hofman, Wayne S Cutfield
No abstract text is available yet for this article.
February 1, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28182843/inhibitory-effects-of-red-wine-on-lipid-oxidation-in-fish-oil-emulsion-and-angiogenesis-in-zebrafish-embryo
#17
Haiyan Sun, Yulin Zhang, Yixiao Shen, Yongchao Zhu, Hua Wang, Zhimin Xu
The capabilities of red wine against lipid oxidation and angiogenesis were evaluated by using a fish oil emulsion system and an in vivo zebrafish embryos model, respectively. The red wine contained 12 different antioxidant phenolics which levels were led by anthocyanins (140.46 mg/L), catechin (55.08 mg/L), and gallic acid (46.76 mg/L). The diversity of the phenolics in red wine was greater than the tea, coffee, or white wine selected as a peer control in this study. The total phenolics concentration of red wine was 305...
February 9, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28177723/fish-oil-and-treadmill-exercise-have-age-dependent-effects-on-episodic-memory-and-oxidative-state-of-the-hippocampus
#18
Patrícia Fortes Cavalcanti de Macêdo, Janatar Stella Vasconcelos de Melo, Laís Alves Ribeiro Costa, Glauber Rudá Feitoza Braz, Shirley M de Sousa, Cláudia J Lagranha, Manuella Batista-de-Oliveira Hornsby
There is a growing interest to better understand how lifestyle choices can improve memory functions. Treadmill exercise (Ex) and long-chain n-3 polyunsaturated fatty acids (PUFAs) found in fish oil (Fo) are able to stimulate hippocampal antioxidant defenses and improve memory. The aim was to test whether (Fo) and (Ex) can improve rat's performance on memory tasks and optimize hippocampal antioxidant state in an age-dependent manner. Therefore, young and adult rats were exercised and received (Fo) during four weeks...
January 9, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28166982/dietary-polyunsaturated-fatty-acid-supplementation-of-young-post-pubertal-dairy-bulls-alters-the-fatty-acid-composition-of-seminal-plasma-and-spermatozoa-but-has-no-effect-on-semen-volume-or-sperm-quality
#19
C J Byrne, S Fair, A M English, S A Holden, J R Dick, P Lonergan, D A Kenny
The aim of this study was to examine the effects of dietary supplementation with rumen protected n-6 or n-3 polyunsaturated fatty acids (PUFA) on the quantity and quality of semen from young post-pubertal dairy bulls. Pubertal Holstein-Friesian (n = 43) and Jersey (n = 7) bulls with a mean ± s.e.m. age and bodyweight of 420.1 ± 5.86 days and 382 ± 8.94 kg, respectively, were blocked on breed, weight, age and semen quality (based on the outcomes of two pre-trial ejaculates) and randomly assigned to one of three treatments: (i) a non-supplemented control (CTL, n = 15), (ii) rumen-protected safflower (SO, n = 15), (iii) rumen-protected n-3 PUFA-enriched fish oil (FO, n = 20)...
March 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28114864/effect-of-different-dextrose-equivalents-of-maltodextrin-on-oxidation-stability-in-encapsulated-fish-oil-by-spray-drying
#20
Asmaliza Abd Ghani, Sae Adachi, Hirokazu Shiga, Tze Loon Neoh, Shuji Adachi, Hidefumi Yoshii
Encapsulating fish oil by spray drying with an adequate wall material was investigated to determine if stable powders containing emulsified fish-oil-droplets can be formed. In particular, the dextrose equivalent (DE) of maltodextrin (MD) affects the powder structure, surface-oil ratio, and oxidative stability of fish oil. The carrier solution was prepared using MD with different DEs (DE = 11, 19, and 25) and sodium caseinate as the wall material and the emulsifier, respectively. The percentage of microcapsules having a vacuole was 73, 39, and 38% for MD with DE = 11, 19, and 25, respectively...
April 2017: Bioscience, Biotechnology, and Biochemistry
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