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https://www.readbyqxmd.com/read/29793097/quantitative-assessment-of-placental-perfusion-by-three-dimensional-power-doppler-ultrasound-for-twins-with-selective-intrauterine-growth-restriction-in-one-twin
#1
Wei Sun, Jingyi Liu, Ying Zhang, Ailu Cai, Zeyu Yang, Yili Zhao, Yu Wang, Zhe Cao, Qiuju Wei
OBJECTIVE: We quantitatively assessed placental perfusion using three-dimensional (3D) power Doppler ultrasound for twins with selective intrauterine growth restriction (sIUGR) in one twin. STUDY DESIGN: A prospective cross-sectional study was performed for 104 normal monochorionic diamniotic twins and 30 twins with sIUGR. Twins with sIUGR were divided into two groups: in group I (19 twins), both fetuses had continuous forward end-diastolic blood flow in the umbilical artery; in group II (11 twins), the smaller fetus had a loss or a reverse end-diastolic blood flow in the umbilical artery, but the larger fetus had continuous forward end-diastolic blood flow...
May 17, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29792723/-experimental-promotion-of-liver-regeneration-after-portal-vein-branch-ligation
#2
V Liška, V Třeška, H Mírka, O Vyčítal, J Brůha, L Haidingerová, J Beneš, Z Tonar, R Pálek, J Rosendorf
INTRODUCTION: Portal vein embolization or ligation (PVE/PVL) is part of most multi-stage liver procedures in the case of low future liver remnant volume (FLRV). PVE initiates compensatory hypertrophy of non-occluded liver parenchyma. This hypertrophy is stimulated by an increased volume of portal blood in the non-occluded veins. PVE results in adequate FLRV growth necessary for resection only in 63-96% patients. The aim of this publication is to summarize the possibilities of influencing liver regeneration after PVE/PVL in an experiment using cytokines (TNF-α, IL-6), a monoclonal antibody against TGF-β1 (MAB TGF-β1) and mesenchymal stem cells (MSC)...
2018: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/29792720/-experimental-processing-of-corrosion-casts-of-large-animal-organs
#3
R Pálek, V Liška, L Eberlová, H Mírka, M Svoboda, S Haviar, M Emingr, O Brzoň, P Mik, V Třeška
INTRODUCTION: Corrosion casts (CCs) are used for the visualization and assessment of hollow structures. CCs with filled capillaries enable (with the help of imaging methods) to obtain data for mathematical organ perfusion modelling. As the processing is more difficult in case of organs with greater volume of the vasculature, mainly organs from small animals have been cast up to now. The aim of this study was to optimize the protocol of corrosion casting of different organs of pig. Porcine organs are relatively easily accessible and frequently used in experimental medicine...
2018: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/29792210/quantitative-cardiovascular-magnetic-resonance-extracellular-volume-native-t1-and-18f-fdg-pet-cmr-imaging-in-patients-after-revascularized-myocardial-infarction-and-association-with-markers-of-myocardial-damage-and-systemic-inflammation
#4
Karl P Kunze, Ralf J Dirschinger, Hans Kossmann, Franziska Hanus, Tareq Ibrahim, Karl-Ludwig Laugwitz, Markus Schwaiger, Christoph Rischpler, Stephan G Nekolla
BACKGROUND: Characterization of tissue integrity and inflammatory processes after acute myocardial infarction (AMI) using non-invasive imaging is predictive of patient outcome. Quantitative cardiovascular magnetic resonance (CMR) techniques such as native T1 and extracellular volume (ECV) mapping as well as 18 F-FDG positron emission tomography (PET) imaging targeting inflammatory cell populations are gaining acceptance, but are often applied without assessing their quantitative potential...
May 24, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29791896/deterioration-of-cortical-bone-microarchitecture-critical-component-of-renal-osteodystrophy-evaluation
#5
Ashish K Sharma, Nigel D Toussaint, Rosemary Masterson, Stephen G Holt, Chamith S Rajapakse, Peter R Ebeling, Sindhu T Mohanty, Paul Baldock, Grahame J Elder
BACKGROUND: Cortical bone is a significant determinant of bone strength and its deterioration contributes to bone fragility. Thin cortices and increased cortical porosity have been noted in patients with chronic kidney disease (CKD), but the "Turnover Mineralization Volume" classification of renal osteodystrophy does not emphasize cortical bone as a key parameter. We aimed to assess trabecular and cortical bone microarchitecture by histomorphometry and micro-CT in patients with CKD G5 and 5D (dialysis)...
May 23, 2018: American Journal of Nephrology
https://www.readbyqxmd.com/read/29791696/monocenter-experience-with-532-nm-laser-photoselective-vaporization-of-the-prostate-by-greenlight-xps%C3%A2-laser-is-it-really-an-endourological-joker-card
#6
Jamil Ghahhari, Carlo D'Orta, Ambra Rizzoli, Michele Marchioni, Giulia I Primicer, Piergustavo De Francesco, Angelo Civitella, Mario Di Lecce, Pietro Castellan, Roberto Castellucci, Fabio Neri, Fabiola Raffaella Tamburro, Luca Cindolo, Luigi Schips
INTRODUCTION: In our study, we reported on our monocenter experience with GreenLight (GL) Xcelerated Performance System (XPS)™ /MoXy™ laser fiber (American Medical Systems Inc., Minnetonka, Minnesota), examining its efficacy, safety, and its ability to effectively treat lower urinary tract symptoms (LUTS) in benign prostate obstruction (BPO). We also explored and compared the three different endoscopic approaches used for GL treatment of benign prostatic hyperplasia (BPH), standard photovaporization (PVP), anatomical PVP, and GreenLight XPS™ enucleation of the prostate...
June 1, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29791503/-18f-fdg-and-18f-flt-pet-for-the-evaluation-of-response-to-neo-adjuvant-chemotherapy-in-a-model-of-triple-negative-breast-cancer
#7
Isabella Raccagni, Sara Belloli, Silvia Valtorta, Alessandro Stefano, Luca Presotto, Claudio Pascali, Anna Bogni, Monica Tortoreto, Nadia Zaffaroni, Maria Grazia Daidone, Giorgio Russo, Emilio Bombardieri, Rosa Maria Moresco
RATIONALE: Pathological response to neo-adjuvant chemotherapy (NAC) represents a commonly used predictor of survival in triple negative breast cancer (TNBC) and the need to identify markers that predict response to NAC is constantly increasing. Aim of this study was to evaluate the potential usefulness of PET imaging with [18F]FDG and [18F]FLT for the discrimination of TNBC responders to Paclitaxel (PTX) therapy compared to the response assessed by an adapted Response Evaluation Criteria In Solid Tumors (RECIST) criteria based on tumor volume (Tumor Volume Response)...
2018: PloS One
https://www.readbyqxmd.com/read/29791502/anthropometry-based-24-h-urinary-creatinine-excretion-reference-for-chinese-children
#8
Wei Wang, Cong Du, Laixiang Lin, Wen Chen, Long Tan, Jun Shen, Elizabeth N Pearce, Yixin Zhang, Min Gao, Jianchao Bian, Xiaoming Wang, Wanqi Zhang
To establish 24-h urinary creatinine excretion reference ranges based on anthropometry in healthy Chinese children, a cross-sectional survey was conducted using twice-sampled 24-h urine and anthropometric variables. Age- and sex-specific 24-h creatinine excretion reference ranges (crude and related to individual anthropometric variables) were derived. During October 2013 and May 2014, urine samples were collected. Anthropometric variables were measured in the first survey. Data of 710 children (377 boys and 333 girls) aged 8-13 years who completed the study were analyzed...
2018: PloS One
https://www.readbyqxmd.com/read/29791029/development-of-a-3d-ultrasound-guidance-system-for-permanent-breast-seed-implantation
#9
Justin Michael, Daniel Morton, Deidre Batchelar, Michelle Hilts, Juanita Crook, Aaron Fenster
PURPOSE: Permanent breast seed implantation (PBSI) is a promising radiotherapy technique for early-stage breast cancer, completed in a single visit by permanently implanting 103 Pd seeds using needles inserted through a template and guided by 2D ultrasound (US). However, operator dependence has been highlighted as a limitation of this procedure. Consequently, we propose and have developed an intraoperative guidance system using 3D US and an instrumented mechanical arm to provide intraoperative 3D imaging and needle template tracking...
May 23, 2018: Medical Physics
https://www.readbyqxmd.com/read/29790838/release-of-taurine-and-glutamate-contributes-to-cell-volume-regulation-in-human-retinal-m%C3%A3-ller-cells-differences-in-modulation-by-calcium
#10
Vanina Netti, Alejandro Pizzoni, Martha Peréz-Domínguez, Paula Ford, Herminia Pasantes-Morales, Gerardo Ramos-Mandujano, Claudia Capurro
Neuronal activity in the retina generates osmotic gradients that lead to Müller cell swelling, followed by a regulatory volume decrease (RVD) response, partially due to the isoosmotic efflux of KCl and water. However, our previous studies in a human Müller cell line (MIO-M1) demonstrated that an important fraction of RVD may also involve the efflux of organic solutes. We also showed that RVD depends on the swelling-induced Ca2+ release from intracellular stores. Here we investigate the contribution of Taurine (Tau) and Glutamate (Glu), the most relevant amino acids in Müller cells, to RVD through the volume-regulated anion channel (VRAC), as well as their Ca2+ -dependency in MIO-M1 cells...
May 23, 2018: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29790618/intratendinous-injection-of-autologous-adipose-tissue-derived-mesenchymal-stem-cells-for-the-treatment-of-rotator-cuff-disease-a-first-in-human-trial
#11
Chris H Jo, Jee Won Chai, Eui Cheol Jeong, Sohee Oh, Paul S Kim, Jeong Yong Yoon, Kang Sup Yoon
Despite relatively good results of current symptomatic treatments for rotator cuff disease, there has been an unmet need for fundamental treatments to halt or reverse the progress of disease. The purpose of this study was to assess the safety and efficacy of intratendinous injection of autologous adipose-tissue derived MSCs (AD MSCs) in patients with rotator cuff disease. The first part of the study consists of 3 dose-escalation cohorts; the low- (1.0x107 cells), mid- (5.0x107 ), and high-dose (1.0x108 ) groups with 3 patients each for the evaluation of the safety and tolerability...
May 23, 2018: Stem Cells
https://www.readbyqxmd.com/read/29790567/regional-diversity-in-the-murine-cortical-vascular-network-is-revealed-by-synchrotron-x-ray-tomography-and-is-amplified-with-age
#12
J A Núñez, A Goring, B Javaheri, H Razi, D Gomez-Nicola, A A Pitsillides, P J Thurner, D Gomez-Nicola, P Schneider, C E Clarkin
TCortical bone is permeated by a system of pores, occupied by the blood supply and osteocytes. With ageing, bone mass reduction and disruption of the microstructure are associated with reduced vascular supply. Insight into the regulation of the blood supply to the bone could enhance the understanding of bone strength determinants and fracture healing. Using synchrotron radiation-based computed tomography, the distribution of vascular canals and osteocyte lacunae was assessed in murine cortical bone and the influence of age on these parameters was investigated...
May 23, 2018: European Cells & Materials
https://www.readbyqxmd.com/read/29790430/improvement-of-cellular-health-indicators-and-muscle-quality-in-older-women-with-different-resistance-training-volumes
#13
Paolo M Cunha, Crisieli M Tomeleri, Matheus A do Nascimento, João Pedro Nunes, Melissa Antunes, Hellen C G Nabuco, Ygor Quadros, Edilaine F Cavalcante, Jerry L Mayhew, Luís B Sardinha, Edilson S Cyrino
The main purpose of this study was to compare the effects of resistance training (RT) performed with different training volumes on phase angle (PhA), body water components, and muscle quality (MQ) in untrained older adult women. A second purpose was to assess the relationship between PhA and MQ. Sixty-two older adult women (68.6 ± 5.0 years, 65.2 ± 13.3 kg, 156.1 ± 6.2 cm) were randomly assigned into one of the three groups: two training groups performed either 1 set (G1S) or 3 sets (G3S), or a control group (CG)...
May 23, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29790420/olfactory-training-in-posttraumatic-smell-impairment-mild-improvement-in-threshold-performances-results-from-a-randomized-controlled-trial
#14
Cristobal Langdon, Eduardo Lehrer, Sara Laxe, Isam Alobid, Llorenç Quinto, Joan Berenguer, Franklin Mariño, Montserrat Bernabeu, Concepcio Marin, Joaquim Mullol
Traumatic Brain Injury (TBI) can be associated with partial or total smell loss. Recent studies have suggested that olfactory outcome can be positively modulated after olfactory training (OT). This study's aim was to investigate OT's potential role in smell recovery after TBI-induced olfactory loss. A prospective, randomized, and controlled study was developed. Patients with TBI-induced olfactory dysfunction (N = 42) were randomized into an experimental group with OT and a control group without (nOT). OT was performed twice daily with a 6-odor training set during 12 weeks...
May 23, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29790388/graft-function-assessment-in-mouse-models-of-single-and-dual-kidney-transplantation
#15
Lei Wang, Ximing Wang, Shan Jiang, Jin Wei, Jacentha Buggs, Liying Fu, Jie Zhang, Ruisheng Liu
Animal models of kidney transplantation (KTX) are widely used in studying immune response of hosts to implanted grafts. Additionally, KTX can be used in generating kidney-specific knockout animal models by transplantation of kidneys from donors with global knockout of a gene to wild type recipients or vise verse. Dual kidney transplantation (DKT) provides a more physiological environment for recipients than single kidney transplantation (SKT). However, DKT in mice is rare due to technical challenges. In this study, we successfully performed DKT in mice and compared the hemodynamic response and graft function with SKT...
May 23, 2018: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/29790217/a-sonographic-classification-and-reporting-system-for-diagnosing-adenomyosis
#16
EDITORIAL
Thierry Van den Bosch, Annefleur M de Bruijn, Robert A de Leeuw, Margit Dueholm, Caterina Exacoustos, Lil Valentin, Tom Bourne, D Timmerman, Judith A F Huirne
OBJECTIVE: To develop a uniform classification and standardized reporting system of ultrasound findings of adenomyosis using the Morphological Uterus Sonographic Assessment (MUSA) criteria. METHOD: The opinion presented in this manuscript was built based on a thorough discussion among all authors, including a Delphi procedure. Selected images and videos of typical cases of the different morphological variations of adenomyosis were used in the debates. RESULTS: A classification and reporting system of different types of adenomyosis based on ultrasound was agreed upon including (1) identification of adenomyosis based on MUSA criteria, (2) disease location (anterior, posterior, left lateral, right lateral, fundal), (3) classification of the lesions as focal or diffuse, (4) presence or absence of intralesional cysts, (5) myometrial layer involvement (junctional zone, myometrium, serosal involvement), (6) disease extent (< 25%, 25-50%, > 50% of uterine volume affected by adenomyosis) and (7) lesion size...
May 22, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29790170/calculation-of-breast-volumes-from-mammogram-comparison-of-four-separate-equations-relative-to-mastectomy-specimen-volumes
#17
Jack W Rostas, Neal Bhutiani, Morgan Crigger, Stacey M W Crawford, Reiss B Hollenbach, Samantha R Heidrich, Robert C G Martin, Kelly M McMasters, Nicolás Ajkay
BACKGROUND AND OBJECTIVES: Accurately assessing breast volume (BV) relative to the volume of breast tissue to be removed could help objectively determine the optimal surgical candidates for breast conserving surgery. The objective of this study was to determine the optimal mammography-based method of BV estimation. METHODS: Mammography data was obtained for patients who underwent mastectomy for breast cancer from 2005 to 2015. This data was used to calculate BV using four previously published equations...
May 22, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29790109/value-of-three-dimensional-speckle-tracking-echocardiography-to-assess-left-ventricular-function-in-hyperuricemia-patients
#18
Xiaojie Zhang, Qing Lu, Zhuojun Zhang, Yongle Chen, Yanan Wang, Youngshi Wang, Zheng Li, Lindi Jiang
To assess the value of three-dimensional speckle tracking echocardiography (3D STE) in evaluating the left ventricular (LV) function in hyperuricemia patients. We enrolled 15 healthy controls and 40 hyperuricemia patients and collected and analyzed full-volume 3D STE images of the left ventricle in the apical four-chamber heart view. Laboratory tests and 3D STE parameters, including left ventricular ejection fraction, left ventricular end-diastolic volume, left ventricular end-systolic volume, stroke volume (SV), global longitudinal strain (GLS), and global circumferential strain (GCS), were compared between hyperuricemia patients and healthy controls...
May 22, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29790078/a-prm-approach-for-early-prediction-of-breast-cancer-response-to-chemotherapy-based-on-registered-mr-images
#19
Mohammed El Adoui, Stylianos Drisis, Mohammed Benjelloun
PURPOSE: This study aims to provide and optimize a performing algorithm for predicting the breast cancer response rate to the first round of chemotherapy using Magnetic Resonance Imaging (MRI). This provides an early recognition of breast tumor reaction to chemotherapy by using the Parametric Response Map (PRM) method. METHODS: PRM may predict the breast cancer response to chemotherapy by analyzing voxel-by-voxel temporal intra-tumor changes during one round of chemotherapy...
May 22, 2018: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29790037/one-year-optical-coherence-tomography-findings-in-patients-with-late-and-very-late-stent-thrombosis-treated-with-intravascular-imaging-guided-percutaneous-coronary-intervention
#20
Marcos Ñato, Josep Gomez-Lara, Rafael Romaguera, Gerard Roura, José Luis Ferreiro, Luis Teruel, Montserrat Gracida, Lara Fuentes, Bert Vandeloo, Joan-Antoni Gomez-Hospital, Angel Cequier
Patients with late/very-late stent thrombosis (ST) are at high risk of recurrent-ST. The mechanisms of recurrent-ST are largely unknown. The objective is to describe the 1-year optical coherence tomography (OCT) findings of patients suffering from late/very-late ST treated with intravascular imaging guided percutaneous coronary intervention (PCI). All consecutive patients with late/very-late ST undergoing intravascular imaging guided PCI were screened to undergo coronary angiography and OCT examination at 1 year...
May 22, 2018: International Journal of Cardiovascular Imaging
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