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https://www.readbyqxmd.com/read/29165732/effect-of-melatonin-supplementation-on-antioxidant-status-and-dna-damage-in-high-intensity-trained-athletes
#1
Manuel Ortiz-Franco, Elena Planells, Bartholomé Quintero, Dario Acuña-Castroviejo, Iryna Rusanova, Germaine Escames, Jorge Molina-López
The aim of the study was to evaluate the effect of melatonin supplementation on antioxidant capacity and DNA damage in high intensity interval training (HIIT) athletes. A 2-week randomised, double-blinded, placebo-controlled trial with two groups was conducted. Placebo (PG) and melatonin (MG) (20 mg/d) athletes were monitored over a two-week period of HIIT and strength training. The total antioxidant capacity (TAC) and the glutathione peroxidase (GPx) and superoxide dismutase (SOD) activities were analysed in blood samples...
November 17, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29164363/can-we-hiit-cancer-if-we-attack-inflammation
#2
Efthymios Papadopoulos, Daniel Santa Mina
Physical exercise offers numerous health-related benefits to individuals with cancer. Epidemiologic research has primarily been concerned with conventional exercise training that aligns with the recommendations of 150 min of moderate to vigorous physical activity per week. These recommendations are safe and effective at improving physical and psychosocial outcomes. Given the extensive evidence for generalized physical activity, researchers have begun to explore novel training regimens that may provide additional health benefits and/or improved adherence...
November 21, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/29163192/cycling-before-and-after-exhaustion-differently-affects-cardiac-autonomic-control-during-heart-rate-matched-exercise
#3
Matthias Weippert, Martin Behrens, Anett Mau-Moeller, Sven Bruhn, Kristin Behrens
During cycling before (PRE) and after exhaustion (POST) different modes of autonomic cardiac control might occur due to different interoceptive input and altered influences from higher brain centers. We hypothesized that heart rate variability (HRV) is significantly affected by an interaction of the experimental period (PRE vs. POST) and exercise intensity (HIGH vs. LOW; HIGH = HR > HR at the lactate threshold (HRLT), LOW = HR ≤ HRLT) despite identical average HR. Methods: Fifty healthy volunteers completed an incremental cycling test until exhaustion...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29161767/effects-of-different-endurance-exercise-modalities-on-migraine-days-and-cerebrovascular-health-in-episodic-migraineurs-a-randomized-controlled-trial
#4
Henner Hanssen, Alice Minghetti, Stefano Magon, Anja Rossmeissl, Maria Rasenack, Athina Papadopoulou, Christopher Klenk, Oliver Faude, Lukas Zahner, Till Sprenger, Lars Donath
BACKGROUND: Aerobic exercise training is a promising complementary treatment option in migraine and can reduce migraine days and improve retinal microvascular function. Our aim was to elucidate whether different aerobic exercise programs at high vs. moderate intensities distinctly affect migraine days as primary outcome and retinal vessel parameters as a secondary. METHODS: In this randomized controlled trial, migraine days were recorded by a validated migraine diary in 45 migraineurs of which 36 (female: 28; age: 36 (SD:10)/ BMI: 23...
November 21, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29161419/incidence-of-postoperative-atrial-fibrillation-recurrence-in-patients-discharged-in-sinus-rhythm-after-cardiac-surgery-a-systematic-review-and-meta-analysis
#5
Nicole Lowres, Georgina Mulcahy, Kai Jin, Robyn Gallagher, Lis Neubeck, Ben Freedman
Postoperative atrial fibrillation (POAF) is associated with increased stroke risk and mortality post-discharge. POAF is often considered transient; however, recurrence is likely under-recognized as symptoms are an unreliable guide. Surveillance post-discharge may identify asymptomatic POAF recurrences in patients discharged in sinus rhythm. Therefore, we performed a systematic review and meta-analysis of studies investigating POAF recurrence post-discharge, in patients with new-onset POAF following cardiac surgery who reverted to sinus rhythm prior to discharge...
November 17, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29159914/gaba-concentration-in-sensorimotor-cortex-following-high-intensity-exercise-and-relationship-to-lactate-levels
#6
James P Coxon, Robin F H Cash, Joshua J Hendrikse, Nigel C Rogasch, Ellen Stavrinos, Chao Suo, Murat Yücel
High-intensity exercise increases the concentration of circulating lactate. Cortical uptake of blood borne lactate increases during and following exercise, however the potential relationship with changes in the concentration of neurometabolites remains unclear. While changes in neurometabolite concentration have previously been demonstrated in primary visual cortex following exercise, it remains unknown whether these changes extend to regions such as sensorimotor cortex (SM) or executive regions such as dorsolateral prefrontal cortex (DLPFC)...
November 21, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/29158619/the-effect-of-mineral-based-alkaline-water-on-hydration-status-and-the-metabolic-response-to-short-term-anaerobic-exercise
#7
Jakub Chycki, Tomasz Zając, Adam Maszczyk, Anna Kurylas
Previously it was demonstrated that mineralization and alkalization properties of mineral water are important factors influencing acid-base balance and hydration in athletes. The purpose of this study was to investigate the effects of drinking different types of water on urine pH, specific urine gravity, and post-exercise lactate utilization in response to strenuous exercise. Thirty-six male soccer players were divided into three intervention groups, consuming around 4.0 l/day of different types of water for 7 days: HM (n=12; highly mineralized water), LM (n=12; low mineralized water), and CON (n=12; table water)...
September 2017: Biology of Sport
https://www.readbyqxmd.com/read/29143594/the-gene-smart-study-method-study-design-and-preliminary-findings
#8
REVIEW
Xu Yan, Nir Eynon, Ioannis D Papadimitriou, Jujiao Kuang, Fiona Munson, Oren Tirosh, Lannie O'Keefe, Lyn R Griffiths, Kevin J Ashton, Nuala Byrne, Yannis P Pitsiladis, David J Bishop
The gene SMART (genes and the Skeletal Muscle Adaptive Response to Training) Study aims to identify genetic variants that predict the response to both a single session of High-Intensity Interval Exercise (HIIE) and to four weeks of High-Intensity Interval Training (HIIT). While the training and testing centre is located at Victoria University, Melbourne, three other centres have been launched at Bond University, Queensland University of Technology, Australia, and the University of Brighton, UK. Currently 39 participants have already completed the study and the overall aim is to recruit 200 moderately-trained, healthy Caucasians participants (all males 18-45 y, BMI < 30)...
November 14, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29139007/adding-high-intensity-interval-training-to-conventional-training-modalities-optimizing-health-related-outcomes-during-chemotherapy-for-breast-cancer-the-optitrain-randomized-controlled-trial
#9
Sara Mijwel, Malin Backman, Kate A Bolam, Anna Jervaeus, Carl Johan Sundberg, Sara Margolin, Maria Browall, Helene Rundqvist, Yvonne Wengström
PURPOSE: Exercise training is an effective and safe way to counteract cancer-related fatigue (CRF) and to improve health-related quality of life (HRQoL). High-intensity interval training has proven beneficial for the health of clinical populations. The aim of this randomized controlled trial was to compare the effects of resistance and high-intensity interval training (RT-HIIT), and moderate-intensity aerobic and high-intensity interval training (AT-HIIT) to usual care (UC) in women with breast cancer undergoing chemotherapy...
November 14, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29133220/effects-of-exercise-and-diet-in-nonobese-asthma-patients-a-randomized-controlled-trial
#10
Louise Lindhardt Toennesen, Howraman Meteran, Morten Hostrup, Nina Rica Wium Geiker, Camilla Bjoern Jensen, Celeste Porsbjerg, Arne Astrup, Jens Bangsbo, Debbie Parker, Vibeke Backer
BACKGROUND: Behavioral interventions focusing on exercise and healthy diet improve asthma control in obese patients with asthma, but whether these interventions can lead to improvements in nonobese patients remains unclear. OBJECTIVES: In a randomized, controlled parallel-group design, we studied the effects of an 8-week intervention of either exercise (high-intensity interval training), diet (high protein/low glycemic index), or a combination of the 2, on asthma control and clinical outcomes in nonobese patients with asthma...
November 10, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29127193/maintained-exercise-enhanced-brain-executive-function-related-to-cerebral-lactate-metabolism-in-men
#11
Takeshi Hashimoto, Hayato Tsukamoto, Saki Takenaka, Niels D Olesen, Lonnie G Petersen, Henrik Sørensen, Henning B Nielsen, Niels H Secher, Shigehiko Ogoh
High-intensity interval exercise (HIIE) improves cerebral executive function (EF), but the improvement in EF is attenuated after repeated HIIE, perhaps because of lower lactate availability for the brain. This investigation examined whether improved EF after exercise relates to brain lactate uptake. Fourteen healthy, male subjects performed 2 HIIE protocols separated by 60 min of rest. Blood samples were obtained from the right internal jugular venous bulb and from the brachial artery to determine differences across the brain for lactate (a-v difflactate), glucose (diffglucose), oxygen (diffoxygen), and brain-derived neurotrophic factor (BDNF; diffBDNF)...
November 10, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29124325/changes-in-fat-oxidation-in-response-to-various-regimes-of-high-intensity-interval-training-hiit
#12
REVIEW
Todd Anthony Astorino, Matthew M Schubert
Increased whole-body fat oxidation (FOx) has been consistently demonstrated in response to moderate intensity continuous exercise training. Completion of high intensity interval training (HIIT) and its more intense form, sprint interval training (SIT), has also been reported to increase FOx in different populations. An explanation for this increase in FOx is primarily peripheral adaptations via improvements in mitochondrial content and function. However, studies examining changes in FOx are less common in response to HIIT or SIT than those determining increases in maximal oxygen uptake which is concerning, considering that FOx has been identified as a predictor of weight gain and glycemic control...
November 9, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29108901/keto-adaptation-enhances-exercise-performance-and-body-composition-responses-to-training-in-endurance-athletes
#13
Fionn T McSwiney, Bruce Wardrop, Parker N Hyde, Richard A Lafountain, Jeff S Volek, Lorna Doyle
BACKGROUND: Low-carbohydrate diets have recently grown in popularity among endurance athletes, yet little is known about the long-term (>4 wk) performance implications of consuming a low-carbohydrate high fat ketogenic diet (LCKD) in well-trained athletes. METHODS: Twenty male endurance-trained athletes (age 33 ± 11y, body mass 80 ± 11kg; BMI 24.7 ± 3.1 kg/m(2)) who habitually consumed a carbohydrate-based diet, self-selected into a high-carbohydrate (HC) group (n = 11, %carbohydrate:protein:fat = 65:14:20), or a LCKD group (n = 9, 6:17:77)...
November 3, 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29106772/effects-of-aerobic-interval-training-on-arterial-stiffness-and-microvascular-function-in-patients-with-metabolic-syndrome
#14
Ricardo Mora-Rodriguez, Miguel Ramirez-Jimenez, Valentin E Fernandez-Elias, Maria V Guio de Prada, Felix Morales-Palomo, Jesus G Pallares, Rachael K Nelson, Juan F Ortega
The authors determined the effect of high-intensity aerobic interval training on arterial stiffness and microvascular dysfunction in patients with metabolic syndrome with hypertension. Applanation tonometry was used to measure arterial stiffness and laser Doppler flowmetry to assess microvascular dysfunction before and after 6 months of stationary cycling (training group; n = 23) in comparison to a group that remained sedentary (control group; n = 23). While no variable improved in controls, hypertension fell from 79% (59%-91%) to 41% (24%-61%) in the training group, resulting in lower systolic and diastolic pressures than controls (-12 ± 3 and -6 ± 2 mm Hg, P < ...
November 6, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29105515/implementation-and-evaluation-of-the-norwegian-ullevaal-model-as-a-cardiac-rehabilitation-model-in-primary-care
#15
Birgitta Blakstad Nilsson, Pernille Lunde, Inger Holm
PURPOSE: To describe the Norwegian Ullevaal model, customised for cardiac patients in primary care, and to evaluate the feasibility of the model through patient outcomes after the 12 week outpatient cardiac rehabilitation programme. MATERIALS AND METHODS: A descriptive interventional cohort study with pre-post design. Patients referred to cardiac rehabilitation (n = 273) were enrolled. Group-based high-intensity interval training was offered twice weekly. The primary outcome measure was change in peak oxygen uptake...
November 5, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29101171/high-intensity-interval-exercise-attenuates-but-does-not-eliminate-endothelial-dysfunction-after-a-fast-food-meal
#16
Wesley J Tucker, Brandon J Sawyer, Catherine L Jarrett, Dharini M Bhammar, Justin R Ryder, Siddhartha S Angadi, Glenn A Gaesser
We investigated whether two different bouts of high-intensity interval exercise (HIIE) could attenuate postprandial endothelial dysfunction. Thirteen young (27 ± 1 yr), non-exercise-trained men underwent 3 randomized conditions: (1) HIIE 4x4: four 4-min intervals at 85-95% of maximum heart rate (HRmax) separated by 3 min active recovery, (2) HIIE 16x1: 16 1-min intervals at 85%-95% of HRmax separated by 1 min active recovery, and (3) sedentary control. HIIE was performed in the afternoon, ~18 h prior to the morning fast-food meal (1250 kcal, 63g fat)...
November 3, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29099919/does-strength-promoting-exercise-confer-unique-health-benefits-a-pooled-analysis-of-eleven-population-cohorts-with-all-cause-cancer-and-cardiovascular-mortality-endpoints
#17
Emmanuel Stamatakis, I-Min Lee, Jason Bennie, Jonathan Freeston, Mark Hamer, Gary O'Donovan, Ding Ding, Adrian Bauman, Yorgi Mavros
Public health guidance includes strength-promoting exercise (SPE) but there is little evidence on its links with mortality. Using data from the Health Survey for England (HSE) and Scottish Health Survey (SHS) from 1994-2008 we examined the associations between SPE (gym-based and own bodyweight strength activities) and all-cause, cancer, and cardiovascular disease mortality. Multivariable-adjusted Cox regression examine the associations between SPE (any, low/high volume, adherence to SPE guideline) and mortality...
October 31, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29099031/the-effects-of-acute-high-intensity-interval-training-on-hematological-parameters-in-sedentary-subjects
#18
Muaz Belviranli, Nilsel Okudan, Banu Kabak
The objective of the study was to determine the effects of acute high-intensity interval training (HIIT) on hematological parameters in sedentary men. Ten healthy, non-smoker, and sedentary men aged between 18 and 24 years participated in the study. All subjects performed four Wingate tests with 4 min intervals between the tests. Blood samples were collected at pre-exercise, immediately after, 3 and 6 h after the fourth Wingate test. Hematological parameters were analyzed in these samples. The results showed that hematocrit percentage, hemoglobin values, red cell count, mean cell volume, platelet count, total white cell count, and counts of the white cell subgroups increased immediately after the acute HIIT and their values began to return to resting levels 3 h after exercise, and completely returned to resting levels 6 h after exercise...
July 19, 2017: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29096886/long-term-results-of-high-intensity-exercise-based-cardiac-rehabilitation-in-revascularized-patients-for-symptomatic-coronary-artery-disease
#19
Birgitta Blakstad Nilsson, Pernille Lunde, Haakon Kiil Grøgaard, Inger Holm
Exercise capacity is a strong predictor of survival rate in patients with and without coronary artery disease. Exercise-based cardiac rehabilitation (CR) with improvements in the peak oxygen uptake (VO2peak) of 3.5 ml/kg/min or more has been shown to be beneficial in earlier observational studies. Long-term results on VO2peak after CR are rare. The aim of this study was to assess if a 12-week outpatient CR program including high-intensity interval training would preserve or improve VO2peak 15 months after CR entry...
October 10, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29083942/regular-aerobic-exercise-and-blood-pressure-in-east-asians-a-meta-analysis-of-randomized-controlled-trials
#20
Yutaka Igarashi, Nobuhiko Akazawa, Seiji Maeda
The aim of this meta-analysis was to evaluate the effects of regular aerobic exercise on blood pressure in East Asians. The inclusion criteria of the randomized controlled trials were healthy East Asian adults, exercise group performing regular aerobic exercise and control group not exercising, and a description of the mean systolic blood pressure or diastolic blood pressure at rest. This study included 31 study groups and 1994 subjects. Pooled changes in blood pressure showed significant reductions (systolic blood pressure: -4...
October 30, 2017: Clinical and Experimental Hypertension: CHE
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