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https://www.readbyqxmd.com/read/29146489/exploring-the-barriers-to-and-facilitators-of-using-evidence-based-drugs-in-the-secondary-prevention-of-cardiovascular-diseases-findings-from-a-multistakeholder-qualitative-analysis
#1
Victoria Miller, Lavanya Nambiar, Malvika Saxena, Darryl Leong, Amitava Banerjee, José Pablo Werba, Jose Rocha Faria Neto, Katherine Curi Quinto, Mohammed Moniruzzaman, Shweta Khandelwal
BACKGROUND: Health-system barriers and facilitators associated with cardiovascular medication adherence have seldom been studied, particularly in low- and middle-income countries where uptake rates are poorest. OBJECTIVES: This study sought to explore the major obstacles and facilitators to the use of evidence-supported medications for secondary prevention of cardiovascular disease using qualitative analysis in 2 diverse countries across multiple levels of their health care systems...
November 13, 2017: Global Heart
https://www.readbyqxmd.com/read/29122454/ayurveda-formulations-a-roadmap-to-address-the-safety-concerns
#2
Kishor Patwardhan, Jigyasa Pathak, Rabinarayan Acharya
It is a matter of serious concern that the number of case reports pointing at a possible association between the clinical toxicity and the use of Ayurveda formulations is increasing significantly over the years in scientific medical literature. Though most of these cases are connected with the presence of heavy metals such as lead, mercury and arsenic in these formulations, there are also reports suggesting toxicity due to the presence of toxic chemicals of herbal origin. In the year 2008, the Government of India took an initiative of establishing the National Pharmacovigilance Programme for Ayurveda, Siddha and Unani drugs in a structured way...
November 6, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29118341/novel-serotonin-transporter-regulators-natural-aristolane-and-nardosinane-types-of-sesquiterpenoids-from-nardostachys-chinensis-batal
#3
Ying-Peng Chen, Shu-Song Ying, Hong-Hong Zheng, Yan-Ting Liu, Zhong-Ping Wang, Hu Zhang, Xu Deng, Yi-Jing Wu, Xiu-Mei Gao, Tian-Xiang Li, Yan Zhu, Yan-Tong Xu, Hong-Hua Wu
Serotonin transporter (SERT) is a classic target of drug discovery for neuropsychiatric and digestive disorders, and against those disorders, plants of Nardostachys genus have been valued for centuries in the systems of Traditional Chinese Medicine, Ayurvedic and Unani. Herein, chemical investigation on the roots and rhizomes of Nardostachys chinensis Batal. led to the isolation of forty sesquiterpenoids including six new aristolane-type sesquiterpenoids and six new nardosinane-type sesquiterprenoids. Their structures were elucidated by extensive spectroscopic methods, combined with analyses of circular dichroism and single-crystal X-ray diffraction data...
November 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29105635/clinical-efficacy-of-unani-medicine-renax-for-treatment-of-urolithiasis
#4
Mushtaq Ahmad, Ghazala Shaheen, Saeed Ahmad, Muhammad Akram, Syed Muhammad Ali Shah, Shahbaz Ahmad Zakki
Stone formation occurs most commonly in acute and chronic renal failure. A kidney stone is a solid lump made up of crystals that separate from the urine and build up on the inner surfaces of the kidney. The current study was conducted to investigate the clinical efficacy of Unani medicine Renax in comparison with allopathic medicine (Spironolactone + Furosemide) to treat urolithiasis. The study was conducted in District Dera Ghazi Khan, South Punjab region. This was case control, randomized, double blind clinical study...
September 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29038774/interaction-of-turmeric-curcuma-longa-l-with-beneficial-microbes-a-review
#5
REVIEW
Ajay Kumar, Amit Kishore Singh, Manish Singh Kaushik, Surabhi Kirti Mishra, Pratima Raj, P K Singh, K D Pandey
Curcuma longa L., commonly known as turmeric, is a rhizomatous herb of the family Zingiberaceae. It is mostly used as a spice, a coloring agent and broadly used in traditional medicine such as Ayurveda, Unani, etc., Turmeric rhizomes interact with a large numbers of rhizosphere-associated microbial species, and some enter the plant tissue and act as endophytes. Both rhizospheric and endophytic species are directly or indirectly involved in growth promotion and disease management in plants and also play an important role in the modulation of morphological growth, secondary metabolite production, curcumin content, antioxidant properties, etc...
December 2017: 3 Biotech
https://www.readbyqxmd.com/read/28971830/can-the-ayush-system-be-instrumental-in-achieving-universal-health-coverage-in-india
#6
Janmejaya Samal, Ranjit Kumar Dehury
Universal health coverage (UHC) in the Indian context is understood as easily accessible and affordable health services for all citizens. The Planning Commission of India constituted a High Level Expert Group (HLEG) in October 2010 for the purpose of drafting the guidelines of UHC. While the primary focus of UHC is to provide financial protection to all citizens, its delivery requires an adequate health infrastructure, skilled health human resources, and access to affordable drugs and technologies so that all people receive the level and quality of care they are entitled to...
September 26, 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28875835/the-biological-potentialsof-indian-traditional-medicine-curcumin-for-treating-human-diseases
#7
C S Sumathi
Curcumin is an active compound extracted from the rhizomes of Curcuma longa L. (Turmeric). It possesses a di phenolic structure and there are three important fractions of curcumin namely curcumin, mono-desmethoxycurcumin and bis-desmethoxycurcumin. Curcumin is having high medicinal value. It is widely in Ayurveda, Siddha and Unani medicine formulations to treat various diseases. It is effective against microbial pathogens like bacteria, virus and fungi. It is highly potent and kills cancerous cells. Curcumin exhibits antioxidant activity and reduces lipoperoxidation...
August 30, 2017: Cardiovascular & Hematological Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/28867936/cultural-aspects-of-anxiety-disorders-in-india
#8
Maherra Khambaty, Rajesh M Parikh
Cultural factors have influenced the presentation, diagnoses, and treatment of anxiety disorders in India for several centuries. This review covers the antecedents, prevalence, phenomenology, and treatment modalities of anxiety disorders in the Indian cultural context. It covers the history of the depiction of anxiety in India and the concept of culture in the classification of anxiety disorders, and examines the cultural factors influencing anxiety disorders in India. We review the prevalence and phenomenology of various disorders, such as generalized anxiety disorder, panic disorder, social anxiety, and phobic disorder, as well as culture-specific syndromes such as dhat and koro in India...
June 2017: Dialogues in Clinical Neuroscience
https://www.readbyqxmd.com/read/28867859/pharmacognostical-and-phytochemical-studies-of-helleborus-niger-l-root
#9
V Kishor Kumar, K G Lalitha
BACKGROUND: Helleborus niger L (Ranunculaceae) is used Ayurvedic and Unani systems and other herbal medicine systems. The roots of H. niger have a good medicinal value. AIMS: To conduct a pharmacognostical and phytochemical study of H. niger. MATERIALS AND METHODS: The pharmacognostical studies on roots including parameters such as taxonomical, macroscopic, microscopic characters, physico-chemical, ultra-violet analysis and phytochemical studies are established...
January 2017: Ancient Science of Life
https://www.readbyqxmd.com/read/28745081/ethnobotanical-ethnopharmacological-and-phytochemical-studies-of-myrtus-communis-linn-a-popular-herb-in-unani-system-of-medicine
#10
Mekonnen Sisay, Tigist Gashaw
Myrtus communis L (Myrtaceae) is one of the popular drugs being used in the Unani system of phytomedicine since ancient Greece period. From time immemorial, different parts of this plant and essential oil have been used for a variety of purposes such as cosmetics (hair fall control), flavoring of food and drinks as well as extensive therapeutic purposes. Ethnobotanical information revealed that M communis L has been a folkloric repute for the treatment of several diseases like gastric ulcer, diarrhea, dysentery, cancer, rheumatism, hemorrhage, deep sinuses, leucorrhoea, hemorrhoid, inflammation, dyspepsia, anxiety, insomnia, diabetes, hypertension, pulmonary disorders, and skin diseases...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/28687902/decreased-brain-serotonin-turnover-rate-following-administration-of-sharbat-e-ahmed-shah-produces-antidepressant-and-anxiolytic-effect-in-rats
#11
Muhammad Ahmed, Aisha Azmat
Sharbat-e-Ahmed Shah (SAS) has usually been used in Traditional Unani Medicine (TUM) for depression and insomnia but still not evaluated for its anti-depressant and Neuropharmacological activity. In the present study, a Human dose of SAS (0.6 ml/kg/d) was administered orally to the rats for 15 consecutive days. Antidepressant and anxiolytic were screened scientifically in rats by using Forced swim test and light and dark box test. At the end of study high-performance liquid chromatographic (HPLC) method with electrochemical (EC) detector was used for the measurement of blood and brain tryptophan and brain serotonin levels...
December 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28669703/design-and-development-of-unani-anti-inflammatory-cream
#12
Sana Fatima, Roohi Zaman, Nafis Haider, Shariq Shamsi, Anzar Alam
Inflammation is the symptom of many diseases like rheumatoid arthritis and osteoarthritis. Many side effects are associated with the Non-Steroidal Anti-inflammatory Drugs (NSAIDs) used as conventional treatment for these conditions. In Unani, there are large number of single and compound drugs for inflammatory conditions. One dosage form of Unani system of medicine is named as Zimad in which paste is formed by mixing powder in oil, water, herbal extract. Zimadat is prepared just before application and used in many disease conditions as resolving, styptic, astringent, and antiseptic...
July 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28615021/general-perception-and-self-practice-of-complementary-and-alternative-medicine-cam-among-undergraduate-pharmacy-students-of-bangladesh
#13
Bijoy Laxmi Saha, Md Omar Reza Seam, Md Mainul Islam, Abhijit Das, Sayed Koushik Ahamed, Palash Karmakar, Md Fokhrul Islam, Sukalyan Kumar Kundu
BACKGROUND: Complementary and Alternative Medicine (CAM) is a combination of herbal medicine, traditional therapies, and mind-body intervention. This descriptive study was designed to assess the knowledge, attitudes, perception and self-use of CAM among Bangladeshi undergraduate pharmacy students. The study also evaluated their opinions about its integration into the pharmacy course curriculum. METHODS: It was a cross-sectional, questionnaire-based study conducted on 250 pharmacy students of five reputed public universities of Bangladesh...
June 14, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28608141/triterpenoids-principle-of-wedelia-calendulacea-attenuated-diethynitrosamine-induced-hepatocellular-carcinoma-via-down-regulating-oxidative-stress-inflammation-and-pathology-via-nf-kb-pathway
#14
Amita Verma, Deepika Singh, Firoz Anwar, Prakash Chandra Bhatt, Fahad Al-Abbasi, Vikas Kumar
The aerial part of Wedelia calendulacea have been used in Ayurveda, Unani, Tibetan, Siddha and other folk medicine systems to protect the liver and renal tissue. Liver is considered as primary metabolizing site of body, which is prone to damage by endogenous and exogenous toxicants. A reason for liver toxicity, and major causes of the hepatocellular carcinoma (HCC). 19-α-Hydroxyurs-12(13)-ene-28 oic acid-3-O-β-D-glucopyranoside (HEG), a triterpenoids found in the higher plants, has been known to possess protective effect against various toxicants...
June 12, 2017: Inflammopharmacology
https://www.readbyqxmd.com/read/28607241/composition-and-distribution-of-the-health-workforce-in-india-estimates-based-on-data-from-the-national-sample-survey
#15
Krishna D Rao, Renu Shahrawat, Aarushi Bhatnagar
BACKGROUND: The availability of reliable and comprehensive information on the health workforce is crucial for workforce planning. In India, routine information sources on the health workforce are incomplete and unreliable. This paper addresses this issue and provides a comprehensive picture of India's health workforce. METHODS: Data from the 68th round (July 2011 to June 2012) of the National Sample Survey on the Employment and unemployment situation in India were analysed to produce estimates of the health workforce in India...
September 2016: WHO South-East Asia Journal of Public Health
https://www.readbyqxmd.com/read/28603112/alternative-treatment-in-hepatitis-b-by-using-polyherbal-formulation
#16
RANDOMIZED CONTROLLED TRIAL
Omar Iqbal, Halima Nazar, Samina Afzal, Khan Usmanghani
The hepatitis B is most prevalent diseases (along with morbidities) in Asian countries. This research study has been conducted to provide an alternative treatment which is safe, effective and cost-effective to comprehend relations of disease, symptoms, patients response and the clinical response via better management of hepatitis B. The goal of this research is to evaluate efficacy and safety of herbal medicine as compared to allopathic medicine in patients suffering from hepatitis B. This was a single blind, randomized controlled clinical trial conducted at Shifa-ul-Mulk Memorial Hospital Hamdard University, Karachi and Dar ul Shifa Unani Dawakhana Karachi, Pakistan...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28553349/effects-of-medicinal-plants-on-alzheimer-s-disease-and-memory-deficits
#17
REVIEW
Muhammad Akram, Allah Nawaz
Alzheimer's disease is an age-related neurodegenerative disorder characterized by memory deficits. Various studies have been carried out to find therapeutic approaches for Alzheimer's disease. However, the proper treatment option is still not available. There is no cure for Alzheimer's disease, but symptomatic treatment may improve the memory and other dementia related problems. Traditional medicine is practiced worldwide as memory enhancer since ancient times. Natural therapy including herbs and medicinal plants has been used in the treatment of memory deficits such as dementia, amnesia, as well as Alzheimer's disease since a long time...
April 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28480428/purification-and-fractional-analysis-of-methanolic-extract-of-wedelia-trilobata-possessing-apoptotic-and-anti-leukemic-activity
#18
Uday Venkatesh, Chethan Javarasetty, Satish Kumar Murari
BACKGROUND: Wedelia trilobata (L.) Hitch (WT), commonly known as yellow dots or creeping daisy, is a shrub possessing potent biological activities, and is traditionally used a medicinal plant in Ayurveda, Siddha and Unani systems of medicines, and it has also been tried against leukemia cell line MEG- 01. In the present study, purification and screening of the plant was done for bioactive compounds in methanolic extract of WT for apoptotic and anti-leukemia activity. MATERIALS AND METHODS: The methanolic extract of WT was initially purified through thin layer chromatography (TLC) and screened for the apoptotic and anti-leukemia activities...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28472197/utilization-of-alternative-systems-of-medicine-as-health-care-services-in-india-evidence-on-ayush-care-from-nss-2014
#19
Shalini Rudra, Aakshi Kalra, Abhishek Kumar, William Joe
AYUSH, an acronym for Ayurveda, Yoga and Naturopathy, Unani, Siddha, Sowa-Rigpa and Homeopathy represents the alternative systems of medicine recognized by the Government of India. Understanding the patterns of utilization of AYUSH care has been important for various reasons including an increased focus on its mainstreaming and integration with biomedicine-based health care system. Based on a nationally representative health survey 2014, we present an analysis to understand utilization of AYUSH care across socioeconomic and demographic groups in India...
2017: PloS One
https://www.readbyqxmd.com/read/28462146/comparative-toxicity-study-on-classical-and-modified-version-of-jawarish-jalinoos-a-traditional-unani-formulation-in-rats
#20
Gulam Mohammed Husain, Syed Shoeb Ahmed, Misbahuddin Azhar, Javed Inam Siddiqui, Mohammad Abdul Waheed, Munawwar Husain Kazmi
BACKGROUND: Jawarish Jalinoos (JJ) is a classical semisolid traditional Unani formulation clinically used for the treatment of weakness of vital organs, liver, and stomach. Although JJ has been widely used clinically for several decades, no scientific report is available for its safety. METHODS: JJ and its sugar-free tablet version (SFJJ; formulated to target diabetic population) were assessed for safety in rats. Ninety-day repeated dose oral toxicity study was performed as per the Organisation for Economic Co-operation and Development Guideline 408...
March 2017: Integrative medicine research
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