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femtosecond small incision lenticule extraction

Alper Ağca, Ahmet Demirok, Yusuf Yıldırım, Ali Demircan, Dilek Yaşa, Ceren Yeşilkaya, İrfan Perente, Muhittin Taşkapılı
Small-incision lenticule extraction (SMILE) is an alternative to laser-assisted in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) for the correction of myopia and myopic astigmatism. SMILE can be performed for the treatment of myopia ≤-12 D and astigmatism ≤5 D. The technology is currently only available in the VisuMax femtosecond laser platform. It offers several advantages over LASIK and PRK; however, hyperopia treatment, topography-guided treatment, and cyclotorsion control are not available in the current platform...
2016: Clinical Ophthalmology
Manli Liu, Jianchao Wang, Wen Zhong, Danyang Wang, Yugui Zhou, Quan Liu
PURPOSE: To evaluate the clinical results of suction loss in eyes during small incision lenticule extraction (SMILE). METHODS: This prospective paired-eye case study enrolled 8,490 eyes of 4,296 patients, of which 35 eyes experienced suction loss during the SMILE procedure while being treated for myopia or myopic astigmatism. The eyes with suction loss were re-treated with SMILE, femtosecond laser-assisted LASIK (FS-LASIK), or pseudo SMILE, and the fellow eyes were treated with SMILE...
October 1, 2016: Journal of Refractive Surgery
Ke Zheng, Tian Han, Xingtao Zhou
BACKGROUND: To investigate accommodative response and accommodative lag changes after femtosecond laser small incision lenticule extraction (SMILE) for moderate to high myopia correction. METHODS: A total of 32 eyes of 32 patients with no strabismus who underwent SMILE were enrolled in this prospective clinical study. The accommodative response was obtained viewing monocularly with spherical equivalent refractive error corrected, using an open-field autorefractor at different stimulus levels (2...
October 4, 2016: BMC Ophthalmology
X L Su, Y Wang, W J Wu, Z Q Wu, Y N Wu, C J Yu
Objective: To evaluate and compare the anterior corneal asphericity after small incision lenticule extraction(SMILE)and femtosecond laser in situ keratomileusis(FS-LASIK). Methods: In this case-control study, 45 subjects who underwent SMILE operation comprised the study group, and 33 subjects with FS-LASIK operation comprised the control group. The asphericity coefficient Q-value of the right eyes in both groups was measured at diameters of 6, 7, 8 and 9 mm, respectively, before surgery and at 1 day, 1 week, 1 month and 6 months following surgery...
September 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Hidenaga Kobashi, Kazutaka Kamiya, Kimiya Shimizu
PURPOSE: To compare postoperative ocular surface integrity and innervation between small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK). METHODS: The Cochrane Central Register of Controlled Trials, PubMED, and EMBASE were searched for prospective comparative studies. Trials meeting the selection criteria were quality appraised, and the data were extracted by 2 independent authors. The weighted mean differences (WMDs) and 95% confidence intervals (CIs) were used to compare dry eye examinations and corneal subbasal nerve density (SMILE-FS-LASIK)...
August 24, 2016: Cornea
Hua Li, Yan Wang, Rui Dou, Pinghui Wei, Jiamei Zhang, Wei Zhao, Liuyang Li
PURPOSE: The purpose of this article was to evaluate intraocular pressure (IOP) changes and investigate the relationship with corneal biomechanics after small-incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK). METHODS: A total of 193 eyes of 193 patients who underwent SMILE and FS-LASIK procedures were included in this retrospective study. Data were collected preoperatively and postoperatively, including Goldmann-correlated IOP (IOPg), corneal-compensated IOP (IOPcc), corneal hysteresis (CH), and corneal resistance factor (CRF) by ocular response analyzer, noncontact intraocular pressure (IOPNCT) by noncontact tonometer, and Ehlers, Shah, Dresden, Kohlhaas, Orssengo/Pye by the Pentacam corrected system...
August 1, 2016: Investigative Ophthalmology & Visual Science
Marcus Ang, Mohd Farook, Hla M Htoon, Donald Tan, Jodhbir S Mehta
PURPOSE: To describe simulated night vision, night-vision symptoms, and refractive outcomes after small-incision lenticule extraction. SETTING: Tertiary referral eye center, Singapore. DESIGN: Prospective case series. METHODS: All patients had small-incision lenticule extraction using the Visumax 500 kHz femtosecond laser system. The main outcome measure was simulated night vision logMAR corrected distance visual acuity (CDVA) using the super vision test-night vision goggle vision chart at 12 months...
August 2016: Journal of Cataract and Refractive Surgery
Z X Dong, L He, Z Y Sun, Y Shen, R Y Chu, X T Zhou
OBJECTIVE: To evaluate the morphological changes during corneal wound healing after small incision lenticule extraction (SMILE). METHODS: Twenty-one New Zealand white rabbits were randomly divided into 2 groups (group A of 12 rabbits and group B of 9 rabbits) using the toss of a coin. All the right eyes were treated. Group A underwent SMILE, and group B underwent femtosecond laser-assisted in situ keratomileusis (LASIK), with the same refractive corrections of-6...
July 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
David P Piñero, Miguel A Teus
UNLABELLED: Small-incision lenticule extraction and wavefront-guided femtosecond-assisted laser in situ keratomileusis (LASIK) provide good visual outcomes and an efficacious correction of myopia or myopic astigmatism with similar levels of safety. Some differences in predictability and the percentage of eyes gaining lines of corrected distance visual acuity are present. A higher level of coma is present after small-incision lenticule extraction, with no clear differences between techniques in spherical aberration...
July 2016: Journal of Cataract and Refractive Surgery
Yang Jiang, Ying Li, Xiao-Wei Liu, Jing Xu
BACKGROUND: Small incision refractive lenticule extraction (SMILE) is an effective laser procedure that treats myopia. This research was to describe a novel approach to treat corneal ulcer or perforation using the corneal lenticules obtained from SMILE and to evaluate the safety and effectiveness of tectonic keratoplasty with femtosecond laser intrastromal lenticule (TEKIL). METHODS: A total of twenty patients (22 eyes) were monitored for at least 6 months and were assessed using slit lamp microscopy, optical coherence tomography, and best-corrected visual acuity (BCVA)...
August 5, 2016: Chinese Medical Journal
Tamer H Massoud, Osama Ibrahim, Kitty Shehata, Moones F Abdalla
Purpose. To evaluate the visual and refractive outcomes after small incision lenticule extraction (SMILE) for treating myopia and myopic astigmatism after penetrating keratoplasty (PKP). Design. Case-series. Methods. Ten eyes of 10 patients with previous PKP and residual myopic astigmatism for whom pentacam imaging and thickness measurements were acceptable for laser vision correction. Manifest refraction (MR), uncorrected distance visual acuity (UDVA), and corrected distance visual acuity (CDVA) were obtained preoperatively and one day, one week, and one, 3, and 6 months postoperatively...
2016: Journal of Ophthalmology
Jaakko S Mattila, Juha M Holopainen
PURPOSE: To describe a case of bilateral ectasia after small incision lenticule extraction (SMILE) in a patient with early keratoconus. METHODS: Case report. RESULTS: Bilateral SMILE was performed on a patient even though preoperative topographies showed changes indicating early keratoconus. The right eye underwent further photorefractive keratectomy enhancement 18 months later. The patient developed a bilateral corneal ectasia. CONCLUSIONS: This case underlines the importance of thorough preoperative assessment for possible keratoconus suspect changes with corneal topography to avoid postoperative ectasia...
July 1, 2016: Journal of Refractive Surgery
Zeren Shen, Keda Shi, Yinhui Yu, Xiaoning Yu, Yuchen Lin, Ke Yao
PURPOSE: The goal of this study was to compare small incision lenticule extraction (SMILE) with femtosecond laser-assisted in situ keratomileusis (FS-LASIK) for treating myopia. METHODS: The CENTRAL, EMBASE, PubMed databases and a Chinese database (SinoMed) were searched in May of 2016. Twelve studies with 1,076 eyes, which included three randomized controlled trials (RCTs) and nine cohorts, met our inclusion criteria. The overall quality of evidence was evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group framework...
2016: PloS One
Jing Ma, Nan-Jue Cao, Li-Kun Xia
AIM: To identify possible differences of efficacy, safety, predictability, higher-order aberrations and corneal biomechnical parameters after small-incision lenticule extraction (SMILE) and femtosecond lenticule extraction (FLEx). METHODS: A systematic literature retrieval was conducted in Medline, Embase and the Cochrane Library, up to October, 2015. The included studies were subject to a Meta-analysis. Comparison between SMILE and FLEx was measured as pooled odds ratio (OR) or weighted mean differences (WMD)...
2016: International Journal of Ophthalmology
Nicolae Miruna, Filip Andrei, Filip Mircea Vasile, Eugen Rotaru
Our paper is an introduction in this new generation of Laser vision correction, called SMILE. It also reveals our experience in the past year, since we started to perform this new procedure in our patients. Small Incision Lenticule Extraction technique is the 3rd generation of Laser vision correction that completely redefines refractive surgery. Being performed entirely with femtosecond laser, SMILE is tissue preserving and very gentle for the eye. In 2011, it was launched internationally. We have started with SMILE in October 2014...
January 2016: Romanian Journal of Ophthalmology
Gary Hin-Fai Yam, Nur Zahirah Binte M Yusoff, Tze-Wei Goh, Melina Setiawan, Xiao-Wen Lee, Yu-Chi Liu, Jodhbir S Mehta
Small incision lenticule extraction (SMILE) becomes a procedure to correct myopia. The extracted lenticule can be used for other clinical scenarios. To prepare for allogeneic implantation, lenticule decellularization with preserved optical property, stromal architecture and chemistry would be necessary. We evaluated different methods to decellularize thin human corneal stromal lenticules created by femtosecond laser. Treatment with 0.1% sodium dodecylsulfate (SDS) followed by extensive washes was the most efficient protocol to remove cellular and nuclear materials...
2016: Scientific Reports
Yingjie Zhang, Qin Shen, Yan Jia, Dan Zhou, Jibo Zhou
PURPOSE: To assess possible differences in clinical outcomes when small-incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK (FS-LASIK) are used to correct myopia. METHODS: A systematic review and meta-analysis. A systematic literature search was performed using Cochrane Collaboration methodology to identify randomized controlled trials and appropriate comparative studies comparing SMILE and FS-LASIK for myopia. RESULTS: The authors identified 11 studies from a review of 102 articles, involving a total of 1,101 eyes, of which 532 eyes (48...
April 2016: Journal of Refractive Surgery
Wenjing Wu, Yan Wang
OBJECTIVES: To investigate the corneal higher-order aberrations (HOAs) of the anterior surface, posterior surface, and total cornea after small incision lenticule extraction (SMILE) and compare the results using femtosecond laser-assisted in situ keratomileusis (FS-LASIK) and femtosecond laser lenticule extraction (FLEx). METHODS: This study included 160 eyes in total; 73 eyes underwent SMILE, 52 eyes underwent FS-LASIK, and 35 eyes underwent FLEx surgery. Corneal HOAs of the anterior surface, posterior surface, and total cornea were evaluated using a Scheimpflug camera over 6-mm diameter preoperatively and 3 months postoperatively...
March 29, 2016: Eye & Contact Lens
Kishore R Pradhan, Dan Z Reinstein, Glenn I Carp, Timothy J Archer, Marine Gobbe, Purushottam Dhungana
PURPOSE: To evaluate the outcomes of small-incision lenticule extraction for myopia using the Visumax femtosecond laser at the first refractive surgery unit in Nepal during the first 30 months of operation. SETTING: Tilganga Institute of Ophthalmology, Kathmandu, Nepal. DESIGN: Retrospective noncomparative case series. METHODS: Consecutive myopic small-incision lenticule extraction procedures by a fellowship-trained surgeon were evaluated...
February 2016: Journal of Cataract and Refractive Surgery
Ihab M Osman, Ramy Awad, Wei Shi, Mohamed Abou Shousha
PURPOSE: To determine the incidence of and analyze risk factors for suction loss during femtosecond laser-assisted small incision lenticule extraction in the management of myopia or myopic astigmatism. SETTING: Roayah Vision Correction Center, Alexandria, Egypt. DESIGN: Retrospective comparative case-control study. METHODS: All eyes that had femtosecond laser-assisted small-incision lenticule extraction for the correction of myopia and myopic astigmatism performed between August 2010 and April 2014 were included...
February 2016: Journal of Cataract and Refractive Surgery
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