Zhenpeng Zhang, Yao Zhang, Yuan Li, Songhao Jiang, Feng Xu, Kaixuan Li, Lei Chang, Huiying Gao, Predrag Kukic, Paul Carmichael, Mark Liddell, Jin Li, Qiang Zhang, Zhitang Lyu, Shuangqing Peng, Tao Zuo, Liz Tulum, Ping Xu
Protein phosphorylation is the most common type of post-translational modification where serine, threonine or tyrosine are reversibly bound to the phosphate group of ATP in a reaction catalyzed by protein kinases. Phosphorylation plays an important role in regulation of cell homeostasis, including but not limited to signal perception and transduction, gene expression and function of proteins. Protein phosphorylation happens on a fast time scale and represents an energy-efficient way for the cell to adapt to exposure to chemical stressors...
June 7, 2022: Toxicology and Applied Pharmacology