keyword
MENU ▼
Read by QxMD icon Read
search

Hormesis

keyword
https://www.readbyqxmd.com/read/29305106/diabetic-nephropathy-is-there-a-role-for-oxidative-stress
#1
REVIEW
Manpreet K Sagoo, Luigi Gnudi
Oxidative stress has been implicated in the pathophysiology of diabetic nephropathy. Studies in experimental animal models of diabetes strongly implicate oxidant species as a major determinant in the pathophysiology of diabetic kidney disease. The translation, in the clinical setting, of these concepts have been quite disappointing, and new theories have challenged the concepts that oxidative stress per se plays a role in the pathophysiology of diabetic kidney disease. The concept of mitochondrial hormesis has been introduced to explain this apparent disconnect...
January 2, 2018: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29284298/originator-of-the-hormesis-concept-rudolf-virchow-or-hugo-schulz
#2
E J Calabrese
In 2006, Henschler disputed the claim of Calabrese and Baldwin that Hugo Schulz should be considered the originator of the hormesis concept. Henschler cited an 1854 paper by Rudolf Virchow on the effects of two agents on the beating of cilia, which showed a hormetic-biphasic dose response. The interpretation of Henschler became broadly accepted over the past decade based on citations in the literature. However, a recent translation of the Virchow paper from German into English reveals that the claims of Henschler are not supported by the article...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/29277034/single-and-mixture-toxicities-of-bde-47-6-oh-bde-47-and-6-meo-bde-47-on-the-feeding-activity-of-daphnia-magna-from-behavior-assessment-to-neurotoxicity
#3
Yanhua Liu, Ruixin Guo, Shengkai Tang, Fengyi Zhu, Shenghu Zhang, Zhengyu Yan, Jianqiu Chen
Although 2,2',4,4'-tetrabrominated diphenyl ether (BDE-47), 6-hydroxy-2,2',4,4'-tetrabromodiphenyl ether (6-OH-BDE-47) and 6-methoxy-2,2',4,4'-tetrabromodiphenyl ether (6-MeO-BDE-47) clearly disrupt the endocrine system, current knowledge of their single and/or mixture toxicities on other behaviors of aquatic organisms remains limited. In the present study, Daphnia magna was used to investigate the single and mixture toxicities of BDE-47, 6-OH-BDE-47 and 6-MeO-BDE-47 as measured by inhibition of feeding during exposure and post-exposure periods...
December 20, 2017: Chemosphere
https://www.readbyqxmd.com/read/29259458/theory-about-the-embryo-cryo-treatment
#4
REVIEW
Iavor K Vladimirov, Desislava Tacheva, Antonio Diez
Background: To create hypothesis, which can give a logical explanation related to the benefits of freezing/thawing embryos. Cryopreservation is not only a technology used for storing embryos, but also a method of embryo treatment that can potentially improve the success rate in infertile couples. Methods: From the analysis of multiple results in assisted reproductive technology, which have no satisfactory explanation to date, we found evidence to support a 'therapeutic' effect of the freezing/thawing of embryos on the process of recovery of the embryo and its subsequent implantation...
April 2017: Reproductive Medicine and Biology
https://www.readbyqxmd.com/read/29244952/metabolic-responses-of-mytilus-galloprovincialis-to-fullerenes-in-mesocosms-exposure-experiments
#5
Josep Sanchís, Marta Llorca, Mar Olmos, Gabriella Francesca Schirinzi, Cristina Bosch-Orea, Esteban Abad, Damia Barcelo, Marinella Farre
In this study, Mediterranean mussels (Mytilus galloprovincialis) were exposed through the diet to fullerene soot, at three concentrations in parallel to a control group. Their metabolomics response was assessed by high-performance liquid chromatography coupled to high-resolution mass spectrometry (HPLC-HRMS). The experiments were conducted in marine mesocosms, during 35 days (7 days of acclimatization, 21 days of exposure and 7 seven days of depuration). Real conditions were emulated in terms of physicochemical conditions of the habitat...
December 15, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29238274/hormetic-response-by-silver-nanoparticles-on-in-vitro-multiplication-of-sugarcane-saccharum-spp-cv-mex-69-290-using-a-temporary-immersion-system
#6
Jericó J Bello-Bello, Rocío A Chavez-Santoscoy, Carlos A Lecona-Guzmán, Nina Bogdanchikova, Josafhat Salinas-Ruíz, Fernando Carlos Gómez-Merino, Alexey Pestryakov
Background: Hormesis is considered a dose-response phenomenon characterized by growth stimulation at low doses and inhibition at high doses. The hormetic response by silver nanoparticles (AgNPs) on in vitro multiplication of sugarcane was evaluated using a temporary immersion system. Methods: Sugarcane shoots were used as explants cultured in Murashige and Skoog medium with AgNPs at concentrations of 0, 25, 50, 100, and 200 mg/L. Shoot multiplication rate and length were used to determine hormetic response...
October 2017: Dose-response: a Publication of International Hormesis Society
https://www.readbyqxmd.com/read/29225559/hormesis-and-homeopathy-toward-a-new-self-consciousness
#7
Andrea Dei
No abstract text is available yet for this article.
October 2017: Dose-response: a Publication of International Hormesis Society
https://www.readbyqxmd.com/read/29191860/hormesis-like-effect-of-mild-larval-crowding-on-thermotolerance-in-drosophila-flies
#8
Henry Youn, Renault David, Colinet Hervé
Crowding is a complex stress that can affect organisms' physiology, especially through decreased food quality and accessibility. Here, we evaluated the effect of larval density on several biological traits of Drosophila melanogaster An increasing gradient, from 1 to 1000 eggs per milliliter of food, was used to characterize life-history traits variations. Crowded conditions resulted in striking decreases of fresh mass (up to six-fold) and viability, as well as delayed development. Next, we assessed heat and cold tolerance in L3 larvae reared at three selected larval densities: low (LD, 5 eggs...
November 30, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29133226/the-effect-of-dietary-neonicotinoid-pesticides-on-non-flight-thermogenesis-in-worker-bumble-bees-bombus-terrestris
#9
Robert Potts, Rebecca M Clarke, Sophie E Oldfield, Lisa K Wood, Natalie Hempel de Ibarra, James E Cresswell
For bumble bees (genus Bombus), the capacity for non-flight thermogenesis is essential for two fundamental processes undertaken by adult workers, namely recovery from torpor after chilling and brood incubation. Farmland bees can be widely exposed to dietary residues of neurotoxic neonicotinoid insecticides that appear in the nectar and pollen of treated bee-attractive crops, which may harm them. An earlier study shows that dietary neonicotinoids cause complex alterations to thermoregulation in honey bees, but their effects on the thermogenic capabilities of individual bumble bees has been untested previously...
November 10, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/29126094/evolutionarily-adapted-hormesis-inducing-stressors-can-be-a-practical-solution-to-mitigate-harmful-effects-of-chronic-exposure-to-low-dose-chemical-mixtures
#10
REVIEW
Se-A Kim, Yu-Mi Lee, Je-Yong Choi, David R Jacobs, Duk-Hee Lee
Although the toxicity of synthetic chemicals at high doses is well known, chronic exposure to low-dose chemical mixtures has only recently been linked to many age-related diseases. However, it is nearly impossible to avoid the exposure to these low-dose chemical mixtures as humans are exposed to a myriad of synthetic chemicals as a part of their daily lives. Therefore, coping with possible harms due to low dose chemical mixtures is challenging. Interestingly, within the range of environmental exposure, disease risk does not increase linearly with increasing dose of chemicals, but often tends to plateau or even decrease with increasing dose...
November 7, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29115439/low-dose-irradiation-inhibits-proliferation-of-the-p53null-type-human-prostate-cancer-cells-through-the-atm-p21-pathway
#11
Si-Jie Li, Xin-Yue Liang, Hai-Jun Li, Guo-Zi Yang, Wei Li, Zhuo Li, Lei Zhou, Xue Wen, De-Hai Yu, Jiu-Wei Cui
Low-dose ionizing radiation (LDIR) induces hormesis, exerts an adoptive effect on normal mammalian cells and stimulates cell proliferation; however, this effect is absent in cancer cells. Little is known on the molecular mechanisms underlying this differential response between normal and cancer cells. In the present study, it was demonstrated that the human prostate cancer cell line PC-3 and the normal prostate cell line RWPE-1 exhibited differential biological responses to LDIR. Through cell cycle analyses, it was demonstrated that LDIR inhibited cell growth and arrested the cell cycle at the S and G2/M phases in PC-3 cells, but not in RWPE-1 cells...
November 7, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29105050/knowledge-and-awareness-of-radiation-hazards-among-palestinian-radio-technologists
#12
Ahmed Hamarsheh, Ahmad Amro
This study investigated 94.4% of Palestinian radio technologists and the mean percentage of correct answers for knowledge and awareness questions was 26.4%. The percentage of correct answers for questions testing knowledge of the ALARA (As Low As Reasonably Achievable) principle and hormesis hypothesis was 66.5% and 17.2%, respectively. Radio technologists with education level higher than bachelor degree and < 5 years' work experience showed a significantly higher level of knowledge. The most radiosensitive organs were correctly identified as the lungs and stomach by 6...
October 30, 2017: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29091795/toxic-responses-of-microorganisms-to-nickel-exposure-in-farmland-soil-in-the-presence-of-earthworm-eisenia-fetida
#13
Xiaoqian Xia, Siyuan Lin, Jun Zhao, Wei Zhang, Kuangfei Lin, Qiang Lu, Bingsheng Zhou
Nickel (Ni)-contamination impairs soil ecosystem, threatening human health. A laboratory simulation of Ni-polluted farmland soil study, in the presence or absence of earthworm, was carried out to investigate the toxic responses of soil microorganisms, including microbial biomass C (MBC), soil basal respiration (SBR), metabolic quotient (qCO2), urease (UA) and dehydrogenase activities (DHA). Additionally, the variations of Ni bioavailability were also explored. Results manifested that MBC and SBR were stimulated at 50 and 100 mg·kg(-1) of Ni but inhibited by further increasing Ni level, showing a Hormesis effect...
October 26, 2017: Chemosphere
https://www.readbyqxmd.com/read/29081787/plant-hormesis-management-with-biostimulants-of-biotic-origin-in-agriculture
#14
REVIEW
Marcela Vargas-Hernandez, Israel Macias-Bobadilla, Ramon G Guevara-Gonzalez, Sergio de J Romero-Gomez, Enrique Rico-Garcia, Rosalia V Ocampo-Velazquez, Luz de L Alvarez-Arquieta, Irineo Torres-Pacheco
Over time plants developed complex mechanisms in order to adapt themselves to the environment. Plant innate immunity is one of the most important mechanisms for the environmental adaptation. A myriad of secondary metabolites with nutraceutical features are produced by the plant immune system in order to get adaptation to new environments that provoke stress (stressors). Hormesis is a phenomenon by which a stressor (i.e., toxins, herbicides, etc.) stimulates the cellular stress response, including secondary metabolites production, in order to help organisms to establish adaptive responses...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29080703/hormesis-as-a-mechanistic-approach-to-understanding-herbal-treatments-in-traditional-chinese-medicine
#15
REVIEW
Dali Wang, Edward J Calabrese, Baoling Lian, Zhifen Lin, Vittorio Calabrese
Traditional Chinese medicine (TCM) has been long practiced and is becoming ever more widely recognized as providing curative and/or healing treatments for a number of diseases and physiological conditions. This paper posits that herbal medicines used in TCM treatments may act through hormetic dose-response mechanisms. It is proposed that the stimulatory (i.e., low dose) and inhibitory (i.e., high dose) components of the hormetic dose response correspond to respective "regulating" and "curing" aspects of TCM herbal treatments...
October 25, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28983749/first-study-of-hormesis-effect-on-mushroom-cultivation
#16
Diego Cunha Zied, Fernanda Aparecida Dourado, Eustáquio Souza Dias, Arturo Pardo-Giménez
The use of fungicides is common in mushroom cultivation, but no study was carried out applying reduced doses of fungicides in order to increase yield, taking account the hormesis effect. The aim of this manuscript was to verify the effects of different concentrations of fungicides to stimulate the productivity of different strains of Agaricus bisporus. Two stages were developed, an in vitro study to define the best concentration to be applied in the second experiment an agronomic study, which consisted of the application of the selected fungicides, in their respective concentrations, in an experiment carried out in the mushroom chamber...
October 5, 2017: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/28975358/nicosulfuron-plus-atrazine-herbicides-and-trichogrammatidae-hymenoptera-in-no-choice-test-selectivity-and-hormesis
#17
Germano L D Leite, Paula D de Paulo, José C Zanuncio, Wagner de S Tavares, Anarelly C Alvarenga, Luan R Dourado, Edilson P R Bispo, Marcus A Soares
The aim of this study was to evaluate the effect of the herbicide mixture nicosulfuron + atrazine on 10 trichogrammatid species. A female of each trichogrammatid was placed in a test tube (no-choice) with a card with 45 Anagasta kuehniella eggs. Parasitism was allowed over a 48 h period, then the cards were sprayed with a solution containing nicosulfuron (30 g ha(-1)) + atrazine (1500 g ha(-1)), besides the control (distilled water). The nicosulfuron + atrazine mixture increased the Trichogramma atopovirilia and T...
November 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28955983/on-mechanism-of-antioxidant-effect-of-fullerenols
#18
A S Sachkova, E S Kovel, G N Churilov, O A Guseynov, A A Bondar, I A Dubinina, N S Kudryasheva
Fullerenols are nanosized water-soluble polyhydroxylated derivatives of fullerenes, specific allotropic form of carbon, bioactive compounds and perspective pharmaceutical agents. Antioxidant activity of fullerenols was studied in model solutions of organic and inorganic toxicants of oxidative type - 1,4-benzoquinone and potassium ferricyanide. Two fullerenol preparations were tested: С60О2-4(ОН)20-24 and mixture of two types of fullerenols С60О2-4(ОН)20-24+С70О2-4(ОН)20-24. Bacteria-based and enzyme-based bioluminescent assays were used to evaluate a decrease in cellular and biochemical toxicities, respectively...
March 2017: Biochemistry and Biophysics Reports
https://www.readbyqxmd.com/read/28947171/a-preliminary-attempt-to-establish-multiple-stress-response-profiles-of-human-skin-fibroblasts-exposed-to-mild-or-severe-stress-during-ageing-in-vitro
#19
Suresh I S Rattan, Dino Demirovic, Carine Nizard
Optimal stress response (SR) is an essential aspect of the property of dynamic homeostasis of all biological systems, including cells in culture. Whereas severe stress can induce the so-called stress-induced premature senescence (SIPS), a model developed by Olivier Toussaint, mild stress can strengthen homeodynamics and can postpone senescence through the phenomenon of hormesis. We have attempted to establish multiple stress response profiles (SRP) of early passage young and late passage senescent human facial skin fibroblasts, FSF-1, exposed to either mild (41°C) and severe (43°C) heat shock for 1h, or to mild (2%) and severe (0%) serum deprivation for up to 48h...
September 22, 2017: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/28944077/how-does-hormesis-impact-biology-toxicology-and-medicine
#20
REVIEW
Edward J Calabrese, Mark P Mattson
Hormesis refers to adaptive responses of biological systems to moderate environmental or self-imposed challenges through which the system improves its functionality and/or tolerance to more severe challenges. The past two decades have witnessed an expanding recognition of the concept of hormesis, elucidation of its evolutionary foundations, and underlying cellular and molecular mechanisms, and practical applications to improve quality of life. To better inform future basic and applied research, we organized and re-evaluated recent hormesis-related findings with the intent of incorporating new knowledge of biological mechanisms, and providing fundamental insights into the biological, biomedical and risk assessment implications of hormesis...
2017: NPJ Aging and Mechanisms of Disease
keyword
keyword
96658
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"