Chenhui Lv, Le Cheng, Wenjuan Feng, Haoran Xie, Jie Kou, Lili Wang, Mengqian Shi, Xin Song, Xi Wang, Shuangzhi Chen, Lushan Xue, Cheng Zhang, Xuemin Li, Haifeng Zhao
OBJECTIVES: The study aimed to explore whether TP could improve memory in the aged type 2 diabetic rat model by regulating microbiota-immune-synaptic plasticity axis. METHODS: The experiment was divided into two parts. Firstly, to investigate the effects of TP on the physiopathology of the aged T2DM model rats, rats were randomly divided into the Normal control group, the aged group, the Aged T2DM model group, the TP 75, 150, 300 mg/kg groups, the 150 mg/kg Piracetam group and the 3 mg/kg Rosiglitazone group...
April 15, 2024: Nutritional Neuroscience