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https://www.readbyqxmd.com/read/29034321/refractory-versus-resistant-hypertension-novel-distinctive-phenotypes
#1
Tanja Dudenbostel, Mohammed Siddiqui, Nitin Gharpure, David A Calhoun
Resistant hypertension (RHTN) is relatively common with an estimated prevalence of 10-20% of treated hypertensive patients. It is defined as blood pressure (BP) >140/90 mmHg treated with ≥3 antihypertensive medications, including a diuretic, if tolerated. Refractory hypertension is a novel phenotype of severe antihypertensive treatment failure. The proposed definition for refractory hypertension, i.e. BP >140/90 mmHg with use of ≥5 different antihypertensive medications, including a diuretic and a mineralocorticoid receptor antagonist (MRA) has been applied inconsistently...
September 2017: Journal of Nature and Science
https://www.readbyqxmd.com/read/29033112/gap-between-guidelines-and-clinical-practice-in-heart-failure-with-reduced-ejection-fraction-results-from-tsoc-hfref-registry
#2
Hung-Yu Chang, Chun-Chieh Wang, Jeng Wei, Chong-Yi Chang, Yi-Cheng Chuang, Chien-Long Huang, Eric Chong, Jiunn-Lee Lin, Guang-Yuan Mar, Kuei-Chuan Chan, Jen-Yuan Kuo, Ji-Hung Wang, Zhih-Cherng Chen, Wei-Kung Tseng, Wen-Jin Cherng, Wei-Hsian Yin
BACKGROUND: Heart failure (HF) is a global health problem. Guidelines for the management of HF have been established in Western countries and in Taiwan. However, data from the Taiwan Society of Cardiology-Heart Failure with reduced Ejection Fraction (TSOC-HFrEF) registry showed suboptimal prescription of guideline-recommended medications. We aimed to analyze the reason of non-prescription and clinical outcomes as a result of under-prescription of medications. METHODS: A total of 1509 patients hospitalized for acute HFrEF were recruited in 21 hospitals in Taiwan by the end of October 2014...
October 9, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29032277/marine-ecological-risk-assessment-methods-for-radiation-accidents
#3
Sufen Ye, Luoping Zhang, Huan Feng
Ecological risk assessment (ERA) is a powerful technical tool that can be used to analyze potential and extreme adverse environmental impacts. With the rapid development of nuclear power plants in coastal areas around the world, the establishment of approaches and methodologies for marine ERA with a focus on radiation accidents is an urgent requirement for marine environmental management. In this study, the approaches and methodologies for ERA pertaining to marine radiation accidents (MRA) are discussed and summarized with applications in case studies, such as the nuclear accident in Fukushima, Japan, and a hypothetical accident in Daya Bay, China...
October 12, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29030659/cyclophosphamide-could-be-a-better-choice-than-methotrexate-as-induction-treatment-for-patients-with-more-severe-takayasu-s-arteritis
#4
Ying Sun, Lili Ma, Lingying Ma, Xiufang Kong, Huiyong Chen, Peng Lv, Jiang Lin, Hao Liu, Yan Yan, Zongfei Ji, Chengde Yang, Shengming Dai, Weiguo Wan, Yaohong Zou, Xuejuan Jin, Lindi Jiang
To assess the effectiveness of cyclophosphamide (CYC) versus methotrexate (MTX) for active Takayasu's arteritis (TA). The current study was based on a cohort of TA at Zhongshan Hospital, Fudan University. TA was diagnosed using the 1990 American College of Rheumatology criteria. Fifty-eight subjects receiving induction treatment with CYC (n = 46) or MTX (N = 12) were included in the analysis. Effectiveness and toxicity were assessed in all 58 cases. Clinical remission was defined as: Kerr score reduction to ≤ 1 and glucocorticoids (GC) treatment at a dose of ≤ 0...
October 13, 2017: Rheumatology International
https://www.readbyqxmd.com/read/29020008/effect-of-statin-on-progression-of-symptomatic-basilar-artery-stenosis-and-subsequent-ischemic-stroke
#5
Kyu Sun Yum, Jun Young Chang, Won Joo Jeong, Sangkil Lee, Jin-Heon Jeong, Min-Ju Yeo, Jeong-Ho Hong, Hong-Kyun Park, Inyoung Chung, Beom Joon Kim, Jae Seung Bang, Hee-Joon Bae, Moon-Ku Han
BACKGROUND AND OBJECTIVE: Symptomatic basilar artery stenosis (BAS) is associated with high risk of ischemic stroke recurrence. We aimed to investigate whether statin therapy might prevent the progression of symptomatic BAS and stroke recurrence. METHODS: We retrospectively analyzed the data of patients with acute ischemia with symptomatic BAS, which was assessed using magnetic resonance angiogram (MRA) imaging on admission day, and 1 year later (or the day of the clinical event)...
2017: PloS One
https://www.readbyqxmd.com/read/29019861/the-lateral-thigh-perforator-ltp-flap-for-autologous-breast-reconstruction-a-prospective-analysis-of-138-flaps
#6
Stefania M H Tuinder, Jop Beugels, Arno Lataster, Michiel W de Haan, Andrzej Piatkowski, Michel Saint-Cyr, René R W J van der Hulst, Robert J Allen
BACKGROUND: The septocutaneous tensor fasciae latae (sc-TFL) or lateral thigh perforator (LTP) flap was previously introduced by our group as an alternative flap for autologous breast reconstruction when the abdomen is not suitable as a donor site. The aim of this study was to analyze our experience with the LTP flap and to present the surgical refinements that were introduced. METHODS: A prospective study was conducted of all LTP flap breast reconstructions performed since September 2012...
October 10, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29017985/analogous-3d-ciss-sequences-enhance-the-utility-of-3d-tof-mra-in-delineating-lenticulostriate-arteries-in-insular-gliomas-evidence-from-a-prospective-clinico-radiological-analysis-of-48-patients
#7
Arun S Rao, Sumit Thakar, Narayanam Anantha Sai Kiran, Saritha Aryan, Dilip Mohan, Alangar S Hegde
BACKGROUND: 3D TOF imaging is the current gold standard for non-invasive, preoperative localization of the lenticulostriate arteries (LSAs) in insular gliomas. The utility of this modality is, however, tumour-intensity dependant. METHODS: Forty-eight consecutive patients with insular gliomas were prospectively evaluated over a 3 year period. The location of the LSAs and their relationship with the tumour was determined using a combination of contrast-enhanced coronal 3D TOF MRA and coronal 3D CISS sequences...
October 7, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29016737/diverging-effects-of-enalapril-or-eplerenone-in-primary-prevention-against-doxorubicin-induced-cardiotoxicity
#8
Roger Hullin, Mélanie Métrich, Alexandre Sarre, Denis Basquin, Marc Maillard, Julien Regamey, David Martin
Aims: Clinical studies suggest beneficial effects of renin-angiotensin system blockade for prevention of left ventricular (LV) dysfunction after chemotherapy. However, the efficacy of this strategy as primary prevention has been poorly studied. This study aimed at identifying the pathophysiological mechanisms by which mineralocorticoid receptor antagonism (MRA) or angiotensin converting enzyme inhibition (ACEi) provide protection against doxorubicin-induced cardiotoxicity (DIC) in mouse models of acute and chronic toxicity...
September 7, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/28991731/automatic-temporal-segmentation-of-vessels-of-the-brain-using-4d-asl-mra-images
#9
Renzo Phellan, Thomas Lindner, Michael Helle, Alexandre Falcao, Nils Daniel Forkert
OBJECTIVE: Automatic vessel segmentation can be used to process the considerable amount of data generated by four dimensional arterial spin labeling magnetic resonance angiography (4D ASL MRA) images. Previous segmentation approaches for dynamic series of images propose either reducing the series to a temporal average (tAIP) or maximum intensity projection (tMIP) prior to vessel segmentation, or a separate segmentation of each image. The present paper introduces a method that combines both approaches to overcome the specific drawbacks of each technique...
October 5, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28986631/comparative-reliability-and-diagnostic-performance-of-conventional-3t-magnetic-resonance-imaging-and-1-5t-magnetic-resonance-arthrography-for-the-evaluation-of-internal-derangement-of-the-hip
#10
A Chopra, A J Grainger, B Dube, R Evans, R Hodgson, J Conroy, D Macdonald, Philip Robinson
OBJECTIVE: To compare the diagnostic accuracy of conventional 3T MRI against 1.5T MR arthrography (MRA) in patients with clinical femoroacetabular impingement (FAI). METHODS: Sixty-eight consecutive patients with clinical FAI underwent both 1.5T MRA and 3T MRI. Imaging was prospectively analysed by two musculoskeletal radiologists, blinded to patient outcomes and scored for internal derangement including labral and cartilage abnormality. Interobserver variation was assessed by kappa analysis...
October 6, 2017: European Radiology
https://www.readbyqxmd.com/read/28986225/pediatric-intracranial-aneurysms-considerations-and-recommendations-for-follow-up-imaging
#11
REVIEW
Michael George Zaki Ghali, Visish M Srinivasan, Jacob Cherian, Louis Kim, Adnan Siddiqui, M Ali Aziz-Sultan, Michael Froehler, Ajay Wakhloo, Eric Savageau, Ansaar Rai, Stephen R Chen, Jeremiah Johnson, Sandi K Lam, Peter Kan
BACKGROUND: Pediatric intracranial aneurysms (IAs) are rare. Compared to adult IAs, they are more commonly giant, fusiform, or dissecting. Their treatment often proves more complex and recurrence rate and de novo aneurysmogenesis incidence is higher. A consensus regarding the most appropriate algorithm for following pediatric IAs is lacking. METHODS: We thus sought to generate recommendations based on the reported experience in the literature with pediatric IAs, through a thorough review of the Pubmed database, discussion with experienced neurointerventionalists, and our own experience...
October 3, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28982946/role-of-bronchodilation-and-pattern-of-breathing-in-increasing-expiratory-flow-during-progressive-hypercapnia-in-chronic-obstructive-pulmonary-disease
#12
Kevin E Finucane, Bhajan Singh
Hypercapnia (HC) in-vitro relaxes airway smooth muscle; in-vivo it increases respiratory effort, tidal expiratory flows (V'exp), and, by decreasing inspiratory duration (Ti), increases elastic recoil pressure (Pel) via lung visco-elasticity; however, its effect on airway resistance is uncertain. We examined the contributions of bronchodilation, Ti and expiratory effort to increasing V'exp ̇with progressive HC in 10 COPD subjects, mean FEV1 53% predicted. Lung volumes (Vl), V'exp, esophageal pressure (Pes), Ti and end tidal PCO2 (PetCO2) were measured during 6 tidal breaths followed by an inspiratory capacity (IC), breathing air and at 3 levels of HC...
October 5, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28980056/does-the-type-of-renal-artery-anatomic-variant-determine-the-diameter-of-the-main-vessel-supplying-a-kidney-a-study-based-on-ct-data-with-a-particular-focus-on-the-presence-of-multiple-renal-arteries
#13
Marcin Majos, Ludomir Stefańczyk, Zofia Szemraj-Rogucka, Marcin Elgalal, Raffaele De Caro, Veronica Macchi, Michał Polguj
BACKGROUND: An in-depth knowledge of renal vascular anatomy is essential when planning many surgical procedures; however, a few data exists regarding renal artery diameter. The aim of this study was to assess this morphological feature and to investigate whether a correlation exists between renal artery diameter and the type of arterial supply, with a particular emphasis on variant anatomy and the presence of multiple renal arteries. MATERIALS AND METHODS: Computed tomography angiography (CTA) studies of 248 patients, i...
October 5, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28977406/modified-reverse-aortoplasty-versus-extended-anastomosis-in-patients-with-coarctation-of-the-aorta-and-distal-arch-hypoplasia
#14
Ilya Soynov, Yuriy Sinelnikov, Yuriy Gorbatykh, Alexander Omelchenko, Igor Kornilov, Nataliya Nichay, Alexander Bogachev-Prokophiev, Alexander Karaskov
OBJECTIVES: The aim of our prospective randomized study was to compare modified reverse aortoplasty (MRA) and extended end-to-end anastomosis (EEA). METHODS: We have assessed the operative correction results in 54 infants with coarctation of the aorta and distal aortic arch hypoplasia who underwent primary repair in our institute between July 2013 and February 2014. All of the patients were <12 months old when they had the operation. Patients were randomly assigned to 2 arms: modified reverse subclavian flap angioplasty (MRA group; n  = 27) or extended end-to-end anastomosis (EEA group; n  = 27)...
July 25, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28971250/a-novel-texture-quantization-based-reversible-multiple-watermarking-scheme-applied-to-health-information-system
#15
Mousami Turuk, Ashwin Dhande
The recent innovations in information and communication technologies have appreciably changed the panorama of health information system (HIS). These advances provide new means to process, handle, and share medical images and also augment the medical image security issues in terms of confidentiality, reliability, and integrity. Digital watermarking has emerged as new era that offers acceptable solutions to the security issues in HIS. Texture is a significant feature to detect the embedding sites in an image, which further leads to substantial improvement in the robustness...
October 2, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28970078/evaluation-of-cerebral-arterial-and-venous-system-in-tuberculous-meningitis
#16
Jayantee Kalita, Rajesh K Singh, Usha K Misra, Sunil Kumar
BACKGROUND: Central nervous system infection especially pyogenic results in cerebral venous sinus thrombosis. Tuberculous meningitis (TBM) although associated with infarctions but there is no comprehensive study evaluating the role of CVST contributing in infarction. PURPOSE: To evaluate cerebral arterial and venous system using MR angiography (MRA) and MR venography (MRV) in TBM, and correlate with clinical and MRI findings. MATERIALS AND METHODS: Consecutive patients with TBM were evaluated clinically and their consciousness was assessed by using Glasgow Coma scale...
September 29, 2017: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/28962694/ex%C3%A2-vivo-magnetic-resonance-angiography-to-explore-placental-vascular-anatomy
#17
Bailiang Chen, Jie Duan, Anne-Claire Chabot-Lecoanet, Huanrong Lu, Romain Tonnelet, Oliver Morel, Marine Beaumont
INTRODUCTION: A normal placenta development is crucial for a successful pregnancy. In case of major obstetric complications such as intra-uterine growth restriction, the placental vascularization morphological alteration at macroscopic level is less known than that at microscopic scale. Ex vivo MRA has the potential to visualize whole fresh human placental vasculature fast and efficiently but can be hampered by contrast agent extravasation problem. This study aimed to provide an optimized ex vivo MRA protocol to acquire understanding of global human placenta vasculature morphology...
October 2017: Placenta
https://www.readbyqxmd.com/read/28961750/flow-diverting-stents-for-the-obliteration-of-symptomatic-infectious-cavernous-carotid-artery-aneurysms
#18
Andrew Joshua Kobets, Aleka Scoco, Jonathan Nakhla, Allan Leonard Brook, Merritt Drew Kinon, Nrupen Baxi, David Altschul
BACKGROUND: Intracavernous aneurysms constitute up to 9% of all intracranial aneurysms and 6% are infectious (IIA). First line therapy is a protracted antibiotic course, yet with failure, surgery and endovascular parent vessel sacrifice have been utilized. Reconstructive endovascular therapies have emerged for aneurysm control and may demonstrate a safer therapeutic alternative. OBJECTIVE: To present an IIA treated with a flow-diverting Pipeline stent (ev3 Neurovascular, Irvine, California)...
August 5, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28953897/evaluation-of-cerebral-blood-flow-change-after-cigarette-smoking-using-quantitative-mra
#19
Yunsun Song, Joong-Goo Kim, Hong-Jun Cho, Jae Kyun Kim, Dae Chul Suh
BACKGROUND AND OBJECTIVE: Changes in cerebral blood flow (CBF) immediately after cigarette smoking (CS) are still unclear. Our purpose was to evaluate the hemodynamic changes in each intracranial vessel after CS by using quantitative magnetic resonance angiography (MRA). MATERIAL AND METHODS: Fifteen healthy male smokers less than 45 years old with more than 3 pack-year smoking history were enrolled in this study. The hemodynamic change in the vessels, represented by cerebral flow rate (CFR, ml/s) and flow velocity (FV, cm/s), was quantitatively measured in eleven vascular segments of the brain using phase-contrast MRA...
2017: PloS One
https://www.readbyqxmd.com/read/28948399/interventional-magnetic-resonance-imaging-guided-carotid-embolectomy-using-a-novel-resonant-marker-catheter-demonstration-of-preclinical-feasibility
#20
Jeffrey K Yang, Andre M Cote, Caroline D Jordan, Sravani Kondapavulur, Aaron D Losey, David McCoy, Andrew Chu, Jay F Yu, Teri Moore, Carol Stillson, Fabio Settecase, Matthew D Alexander, Andrew Nicholson, Daniel L Cooke, Maythem Saeed, Dave Barry, Alastair J Martin, Mark W Wilson, Steven W Hetts
To assess the visualization and efficacy of a wireless resonant circuit (wRC) catheter system for carotid artery occlusion and embolectomy under real-time MRI guidance in vivo, and to compare MR imaging modality with x-ray for analysis of qualitative physiological measures of blood flow at baseline and after embolectomy. The wRC catheter system was constructed using a MR compatible PEEK fiber braided catheter (Penumbra, Inc, Alameda, CA) with a single insulated longitudinal copper loop soldered to a printed circuit board embedded within the catheter wall...
September 25, 2017: Biomedical Microdevices
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