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https://www.readbyqxmd.com/read/29471572/-cardiovascular-medication-in-elderly-patients
#1
Robert H G Schwinger
Elderly people show increased probability to develop atherosclerotic diseases; in consequence heart failure - most often following coronary heart disease - as well as atrial fibrillation is more common. Following guidelines may lead to polypharmacy, i. e. use of more than 5 drugs daily. Thus, drug interactions as well as side effects become more likely; especially in elderly patients reduced kidney function has to be taken into account. Only drugs which have shown to prolong life or to reduce symptoms in controlled clinical trials should be used...
February 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29464268/reversible-dilation-of-cerebral-macrovascular-changes-in-melas-episodes
#2
Yuxin Li, Weixingzi Xu, Chong Sun, Jie Lin, Jianxun Qu, Jiawen Cao, Haiqing Li, Liqin Yang
PURPOSE: To investigate the cerebral macrovascular changes as well as the relationship of large vessels and cerebral blood flow (CBF) in mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) using magnetic resonance angiography (MRA) and arterial spin labeling (ASL) perfusion MR imaging (MRI). METHODS: A total of 20 patients diagnosed with MELAS (12 males, 8 females; mean age, 23.3 years) underwent conventional MRI, time-of-flight (TOF) MRA and three dimensional ASL...
February 20, 2018: Clinical Neuroradiology
https://www.readbyqxmd.com/read/29463360/severe-arthritic-changes-following-acetabular-labral-repair-and-femoroplasty-in-an-air-force-pilot
#3
Christopher J Sardon, Mathew L Resnick
BACKGROUND: Acetabular labral tears in the hip have become an increasingly common finding in active duty members due to improved diagnostic capabilities. This has led to a dramatic increase in operative management despite a lack of evidence to support clear long-term benefits. Literature review demonstrated overwhelmingly positive short-term outcomes for labral repairs; however, scattered case reports exist demonstrating debilitating outcomes in young patients, ultimately resulting in total hip arthroplasty...
February 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29456646/an-experimental-rabbit-model-of-symptomatic-cerebral-vasospasm-with-in-vivo-neuroimaging-assessment-and-ex-vivo-histological-validation
#4
Yunchang Mo, Luping Huang, Linbi Chen, Michael Veronesi, Yiyi Shi, Sijia Chen, Linli Peng, Leping Zhou, Yonglin Pu, Junlu Wang
Cerebral vasospasm (CVS) is a severe complication that occurs following aneurysmal subarachnoid hemorrhage (SAH). Magnetic resonance angiography (MRA) has been used to evaluate brain injury following SAH in humans. The present study was designed to assess a rabbit model of symptomatic CVS (SCVS) and the utility of MRA in evaluating SCVS in rabbits. Japanese white rabbits (n=24) were randomly divided into 2 equal groups: A sham group and a SAH group. Neurological scores were evaluated for 7 days following SAH...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29453922/a-short-review-of-primary-aldosteronism-in-a-question-and-answer-fashion
#5
Frederick-Anthony Farrugia, Nicolaos Zavras, Georgios Martikos, Panagiotis Tzanetis, Anestis Charalampopoulos, Evangelos P Misiakos, Dimitrios Sotiropoulos, Nikolaos Koliakos
OBJECTIVES: The aim of this study was to present up to date information concerning the diagnosis and treatment of primary aldosteronism (PA). PA is the most common cause of endocrine hypertension. It has been reported up to 24% of selective referred hypertensive patients. METHODS: We did a search in Pub-Med and Google Scholar using the terms: PA, hyperaldosteronism, idiopathic adrenal hyperplasia, diagnosis of PA, mineralocorticoid receptor antagonists, adrenalectomy, and surgery...
January 1, 2018: Endocrine Regulations
https://www.readbyqxmd.com/read/29442181/do-functional-outcomes-and-cuff-integrity-correlate-after-single-versus-double-row-rotator-cuff-repair-a-systematic-review-and-meta-analysis-study
#6
Mohamed H Sobhy, Ahmed Hany Khater, Medhat Ragab Hassan, Ossama El Shazly
PURPOSE: The purpose of this study is to perform a systematic review and meta-analysis of all available level I prospective randomized controlled trials comparing arthroscopic single-row (SR) with double-row (DR) rotator cuff repairs by both clinical outcomes and radiological re-tear rates. METHODS: PubMed, EMBASE, Google Scholar, and Cochrane databases search was done for level I RCTs comparing clinical and radiological outcomes after SR versus DR rotator cuff repair...
February 13, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29440699/vascular-dysfunction-in-obese-diabetic-db-db-mice-involves-the-interplay-between-aldosterone-mineralocorticoid-receptor-and-rho-kinase-signaling
#7
Aurelie Nguyen Dinh Cat, Glaucia E Callera, Malou Friederich-Persson, Ana Sanchez, Maria Gabriela Dulak-Lis, Sofia Tsiropoulou, Augusto C Montezano, Ying He, Ana M Briones, Frederic Jaisser, Rhian M Touyz
Activation of aldosterone/mineralocorticoid receptors (MR) has been implicated in vascular dysfunction of diabetes. Underlying mechanisms are elusive. Therefore, we investigated the role of Rho kinase (ROCK) in aldosterone/MR signaling and vascular dysfunction in a model of diabetes. Diabetic obese mice (db/db) and control counterparts (db/+) were treated with MR antagonist (MRA, potassium canrenoate, 30 mg/kg/day, 4 weeks) or ROCK inhibitor, fasudil (30 mg/kg/day, 3 weeks). Plasma aldosterone was increased in db/db versus db/+...
February 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29440326/multiparametric-mri-of-intracranial-aneurysms-treated-with-the-woven-endobridge-web-a-case-of-faraday-s-cage
#8
Marie Teresa Nawka, Jan Sedlacik, Andreas Frölich, Maxim Bester, Jens Fiehler, Jan-Hendrik Buhk
OBJECTIVE: To evaluate multiparametric MRI including non-contrast and contrast-enhanced morphological and angiographic techniques for intracranial aneurysms treated with the single-layer Woven EndoBridge (WEB) embolization system applying simultaneous digital subtraction angiography (DSA) as the reference of standard. MATERIALS AND METHODS: We retrospectively identified all patients with incidental and acute ruptured intracranial aneurysms treated with a WEB device (WEB SL and WEB SLS) between March 2014 and June 2016 in our neurovascular center with early (within 7 days) postinterventional multiparametric MRI as well as mid-term (5-8 months) follow-up MRI and DSA available...
February 10, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29434750/comparative-analysis-of-3d-time-resolved-contrast-enhanced-magnetic-resonance-angiography-color-doppler-ultrasound-and-digital-subtraction-angiography-in-symptomatic-carotid-stenosis
#9
Hongkai Cui, Ruifang Yan, Zhansheng Zhai, Jipeng Ren, Zheng Li, Qiang Li, Shouying Wang
The present study aimed to compare the diagnostic value of contrast-enhanced magnetic resonance angiography (CE MRA) with 3D time-resolved imaging of contrast kinetics, color Doppler ultrasound (CDUS) and digital subtraction angiography (DSA) in extracranial carotid stenosis (CS). A total of 54 patients with symptomatic CS were subjected to CDUS, CE MRA and DSA examination. Results of DSA were defined as the standard, and a total of 216 vessels were examined. In each patient four vessels were examined, namely the bilateral common carotid arteries and the bilateral internal carotid arteries...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29427402/retrospective-multi-phase-non-contrast-enhanced-magnetic-resonance-angiography-romance-mra-for-robust-angiogram-separation-in-the-presence-of-cardiac-arrhythmia
#10
Hahnsung Kim, Suhyung Park, Eung Yeop Kim, Jaeseok Park
PURPOSE: To develop a novel, retrospective multi-phase non-contrast-enhanced MRA (ROMANCE MRA) in a single acquisition for robust angiogram separation even in the presence of cardiac arrhythmia. METHODS: In the proposed ROMANCE MRA, data were continuously acquired over all cardiac phases using retrospective, multi-phase flow-sensitive single-slab 3D fast spin echo (FSE) with variable refocusing flip angles, while an external pulse oximeter was in sync with pulse repetitions in FSE to record real-time information on cardiac cycles...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29424126/fewer-peripheral-asymmetrical-cortical-veins-is-a-predictor-of-favorable-outcome-in-mca-infarctions-with-swi-dwi-mismatch
#11
Tao Yuan, Guoli Ren, Guanmin Quan, Duo Gao
BACKGROUND: Outcome prediction of asymmetrical prominent cortical veins (APCVs) on infarction is still debated and may help in selecting patients for reperfusion treatment. PURPOSE: To explore the relationship between fewer peripheral APCVs and the outcome in the patients of acute/subacute middle cerebral artery (MCA) infarctions as well as the relationship between this sign and stenosis of ipsilateral MCA. STUDY TYPE: Retrospective case-control study...
February 9, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29422368/long-term-outcomes-of-low-profile-visualized-intraluminal-support-device-usage-in-stent-assisted-coiling-of-intracranial-aneurysm
#12
Dong Hyun Yoo, Young Dae Cho, Jusun Moon, Jeongjun Lee, Hyun-Seung Kang, Won-Sang Cho, Jeong Eun Kim, Gyojun Hwang, O-Ki Kwon, Moon Hee Han
Stent-assisted coil embolization technique have broadened indications for endovascular therapy of aneurysms. The Low-profile Visualized Intraluminal Support device (LVIS) is a self-expanding, nitinol single-braid and closed-cell device introduced fairly recently. We aim to evaluate long-term outcome of LVIS device in stent-assisted coiling of intracranial aneurysms. Between October 2012 and February 2013, a total of 55 patients with unruptured wide-necked intracranial aneurysms underwent coil embolization procedures involving LVIS devices...
February 5, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29416869/cultural-differences-in-food-and-shape-related-attitudes-and-eating-behavior-are-associated-with-differences-of-body-mass-index-in-the-same-food-environment-cross-sectional-results-from-the-seafarer-nutrition-study-of-kiribati-and-european-seafarers-on-merchant
#13
Joachim Westenhoefer, Robert von Katzler, Hans-Joachim Jensen, Birgit-Christiane Zyriax, Bettina Jagemann, Volker Harth, Marcus Oldenburg
Background: Overweight and obesity is quite prevalent among seafarers. The present study examined differences in BMI and their association with weight, shape and nutrition related attitudes and perceptions among seafarer from Kiribati, a Pacific Island Group, and European origin. Methods: The Seafarer Nutrition Study compared 48 Kiribati and 33 European male seafarers from 4 commercial merchant ships. BMI was calculated from measured weight and height. Attitudes to weight, shape and nutrition and disinhibition of control as a characteristic of eating behavior were assessed in a structured interview...
2018: BMC Obesity
https://www.readbyqxmd.com/read/29414507/a-comparison-of-contrast-free-mra-at-3-0t-in-cases-of-intracranial-aneurysms-with-or-without-subarachnoid-hemorrhage
#14
Ruifang Yan, Bo Zhang, Long Wang, Qiang Li, Fengmei Zhou, Jipeng Ren, Zhansheng Zhai, Zheng Li, Hongkai Cui
PURPOSE: To determine the diagnostic accuracy of contrast-free MRA at 3.0T for detection of intracranial aneurysms in patients with subarachnoid hemorrhage. METHODS: 411 patients (183 with SAH and 228 with non-SAH) underwent MRA. Accuracy, sensitivity, specificity, positive predictive values (PPV), and negative predictive values (NPV) were measured and compared with DSA. RESULTS: Except for a slight difference in sensitivity in patient-based and aneurysm-based evaluations (P=0...
October 25, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29406899/high-intensity-signal-in-the-plaque-on-routine-3d-tof-mra-is-associated-with-ischemic-stroke-in-the-patients-with-low-grade-carotid-stenosis
#15
Kiyofumi Yamada, Shinichi Yoshimura, Manabu Shirakawa, Kazutaka Uchida, Fumiaki Maruyama, Shigehiro Nakahara, Shuji Nishida, Yasuhiro Iwamoto, Yoshikazu Sato, Masanori Kawasaki
BACKGROUND AND PURPOSE: Carotid artery stenosis is one of the major causes of ischemic strokes. However, degree of stenosis is not always correlated with frequency of ischemic strokes. The aim of this study was to evaluate relationships between high intensity signal (HIS) in the carotid plaques on maximum intensity projection (MIP) images detected by routine three-dimensional time-of-flight magnetic resonance angiography (3D-TOF MRA) and ischemic strokes in the patients with low-grade stenosis...
February 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29405357/flow-mri-simulation-in-complex-3d-geometries-application-to-the-cerebral-venous-network
#16
Alexandre Fortin, Stéphanie Salmon, Joseph Baruthio, Maya Delbany, Emmanuel Durand
PURPOSE: Develop and evaluate a complete tool to include 3D fluid flows in MRI simulation, leveraging from existing software. Simulation of MR spin flow motion is of high interest in the study of flow artifacts and angiography. However, at present, only a few simulators include this option and most are restricted to static tissue imaging. THEORY AND METHODS: An extension of JEMRIS, one of the most advanced high performance open-source simulation platforms to date, was developed...
February 5, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29401239/targeted-therapy-of-underlying-conditions-improves-sinus-rhythm-maintenance-in-patients-with-persistent-atrial-fibrillation-results-of-the-race-3-trial
#17
Michiel Rienstra, Anne H Hobbelt, Marco Alings, Jan G P Tijssen, Marcelle D Smit, Johan Brügemann, Bastiaan Geelhoed, Robert G Tieleman, Hans L Hillege, Raymond Tukkie, Dirk J Van Veldhuisen, Harry J G M Crijns, Isabelle C Van Gelder
Aims: Atrial fibrillation (AF) is a progressive disease. Targeted therapy of underlying conditions refers to interventions aiming to modify risk factors in order to prevent AF. We hypothesised that targeted therapy of underlying conditions improves sinus rhythm maintenance in patients with persistent AF. Methods and results: We randomized patients with early persistent AF and mild-to-moderate heart failure (HF) to targeted therapy of underlying conditions or conventional therapy...
February 1, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29398757/atypical-kawasaki-disease-presenting-with-hemiparesis-and-aphasia-a-case-report
#18
Ali Nikkhah
Kawasaki disease (KD) is an inflammatory vasculitis. KD is classified into two groups based on clinical characteristics criteria, namely classic and incomplete. Cerebral vascular abnormality, especially arterial ischemic stroke (AIS) is very rare and unusual in KD. Here, we report a 4-year-old boy who was referred to our tertiary pediatric center with abrupt right hemiparesis and aphasia. At admission time, he had febrile illness and was toxic. On physical examination, we found unilateral left submandibular lymphadenopathy...
January 2018: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29397584/mineralocorticoid-receptor-antagonists-for-heart-failure-a-real-life-observational-study
#19
Noemi Bruno, Gianfranco Sinagra, Stefania Paolillo, Alice Bonomi, Ugo Corrà, Massimo Piepoli, Fabrizio Veglia, Elisabetta Salvioni, Rocco Lagioia, Marco Metra, Giuseppe Limongelli, Gaia Cattadori, Angela B Scardovi, Valentina Carubelli, Domenico Scrutino, Roberto Badagliacca, Marco Guazzi, Rosa Raimondo, Piero Gentile, Damiano Magrì, Michele Correale, Gianfranco Parati, Federica Re, Mariantonietta Cicoira, Maria Frigerio, Maurizio Bussotti, Carlo Vignati, Fabrizio Oliva, Alessandro Mezzani, Giuseppe Vergaro, Andrea Di Lenarda, Claudio Passino, Susanna Sciomer, Giuseppe Pacileo, Roberto Ricci, Mauro Contini, Anna Apostolo, Pietro Palermo, Massimo Mapelli, Cosimo Carriere, Francesco Clemenza, Simone Binno, Romualdo Belardinelli, Carlo Lombardi, Pasquale Perrone Filardi, Michele Emdin, Piergiuseppe Agostoni
AIMS: Mineralocorticoid receptor antagonists (MRAs) have been demonstrated to improve outcomes in reduced ejection fraction heart failure (HFrEF) patients. However, MRAs added to conventional treatment may lead to worsening of renal function and hyperkalaemia. We investigated, in a population-based analysis, the long-term effects of MRA treatment in HFrEF patients. METHODS AND RESULTS: We analysed data of 6046 patients included in the Metabolic Exercise Cardiac Kidney Index score dataset...
February 4, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29393523/measurement-of-kinaesthetic-properties-of-in-brine-table-olives-by-microstructure-of-fracture-surface-sensory-evaluation-and-texture-profile-analysis-tpa
#20
Barbara Lanza, Filomena Amoruso
BACKGROUND: A series of transformations occur in olive fruit both during ripening and processing. In particular, significant changes of the microstructural composition affect the flavour, texture, nutrients and overall quality of the end product. Texture is one of the sensory quality attributes of greatest importance to the consumer acceptance. In the present work, kinaesthetic properties of in-brine table olives of three cultivars of Olea europaea L. (Bella di Cerignola, Peranzana and Taggiasca cvs...
February 2, 2018: Journal of the Science of Food and Agriculture
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