keyword
https://read.qxmd.com/read/38314699/effects-of-hyperventilation-on-repeated-breath-holding-while-in-a-fasting-state-do-risks-outweigh-the-benefits
#21
JOURNAL ARTICLE
Antonis Elia, Mikael Gennser, Ola Eiken, Michail E Keramidas
INTRODUCTION: Breath-holding preceded by either an overnight fast or hyperventilation have been shown to potentiate the risk of a hypoxic blackout. However, no study has explored the combined effects of fasting and hyperventilation on apneic performance and associated physiological responses. METHODS: Nine, non-divers (8 males) attended the laboratory on two separate occasions (≥48-h apart), both after a 12-h overnight fast. During each visit a hyperoxic rebreathing trial was performed followed by three repeated maximal static apneas preceded by either normal breathing (NORM) or a 30s hyperventilation (HYPER)...
February 5, 2024: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://read.qxmd.com/read/38308448/cold-stimulation-of-the-oral-cavity-redistributes-blood-towards-the-brain-in-healthy-volunteers
#22
JOURNAL ARTICLE
Ole Hensel
BACKGROUND: The aim of this study was to analyze cold stimulation-induced changes in cerebral and cardiac hemodynamics. METHODS: Upon ingestion of an ice cube, the changes in resistance index, mean flow velocity and flow index of the middle cerebral arteries (MCA) were assessed using transcranial Doppler sonography. Extracranial duplex sonography was used to measure the mean flow velocity and resistance index of the right internal carotid artery (ICA). The change in mean arterial pressure, heart rate, root mean square of successive differences (RMSSD) and end-tidal carbon dioxide pressure were analyzed additionally...
February 2, 2024: European Journal of Neurology
https://read.qxmd.com/read/38306331/agreement-between-arterial-and-end-tidal-carbon-dioxide-in-adult-patients-admitted-with-serious-traumatic-brain-injury
#23
JOURNAL ARTICLE
Neil Sardesai, Owen Hibberd, James Price, Ari Ercole, Ed B G Barnard
BACKGROUND: Low-normal levels of arterial carbon dioxide (PaCO2) are recommended in the acute phase of traumatic brain injury (TBI) to optimize oxygen and CO2 tension, and to maintain cerebral perfusion. End-tidal CO2 (ETCO2) may be used as a surrogate for PaCO2 when arterial sampling is less readily available. ETCO2 may not be an adequate proxy to guide ventilation and the effects on concomitant injury, time, and the impact of ventilatory strategies on the PaCO2-ETCO2 gradient are not well understood...
2024: PloS One
https://read.qxmd.com/read/38305657/easy-method-to-determine-fluid-responsiveness-in-septic-shock-patients-end-tidal-co2-a-prospective-observational-study
#24
JOURNAL ARTICLE
Hüseyin Özkarakaş, Oğuz Uçar, Zeki Tuncel Tekgül, Özkan Ozmuk, Mehmet Celal Öztürk, Mehmet Uğur Bilgin, Murat Samsa, Halide Hande Şahinkaya, Çagrı Yesilnacar
BACKGROUND: In critically ill patients, especially those with septic shock, fluid management can be a challenging aspect of clinical care. One of the primary steps in treating patients with hemodynamic instability is optimizing intravascular volume. The Passive Leg Raising (PLR) maneuver is a reliable test for assessing fluid responsiveness, as demonstrated by numerous studies and meta-analyses. However, its use requires the measurement of cardiac output, which is often complex and may necessitate clinician experience and specialized equipment...
February 2024: Turkish Journal of Trauma & Emergency Surgery: TJTES
https://read.qxmd.com/read/38299970/effect-of-increasing-blood-pressure-on-brain-tissue-oxygenation-in-adults-after-severe-traumatic-brain-injury
#25
JOURNAL ARTICLE
Thitikan Kunapaisal, Abhijit V Lele, Courtney Gomez, Anne Moore, Marie Angele Theard, Monica S Vavilala
OBJECTIVES: To examine if increasing blood pressure improves brain tissue oxygenation (PbtO2) in adults with severe traumatic brain injury (TBI). DESIGN: Retrospective review of prospectively collected data. SETTING: Level-I trauma center teaching hospital. PATIENTS: Included patients greater than or equal to 18 years of age and with severe (admission Glasgow Coma Scale [GCS] score < 9) TBI who had advanced neuromonitoring (intracranial blood pressure [ICP], PbtO2, and cerebral autoregulation testing)...
February 1, 2024: Critical Care Medicine
https://read.qxmd.com/read/38284537/adult-and-pediatric-porcine-model-of-acute-volume-overload
#26
JOURNAL ARTICLE
Bret D Alvis, Jenna Helmer Sobey, Lexie Vaughn, Christina Jelly, Dawson Wervey, Joyce Cheung-Flynn, Marisa Case, Colleen Brophy, Kyle Hocking
This protocol describes an acute volume overload porcine model for adult Yorkshire pigs and piglets. Both swine ages undergo general anesthesia, endotracheal intubation, and mechanical ventilation. A central venous catheter and an arterial catheter are placed via surgical cutdown in the external jugular vein and carotid artery, respectively. A pulmonary artery catheter is placed through an introducer sheath of the central venous catheter. PlasmaLyte crystalloid solution is then administered at a rate of 100 mL/min in adult pigs and at 20 mL/kg boluses over 10 min in piglets...
January 12, 2024: Journal of Visualized Experiments: JoVE
https://read.qxmd.com/read/38275472/real-time-tracheal-ultrasound-vs-capnography-for-intubation-confirmation-during-cpr-wearing-a-powered-air-purifying-respirator-in-covid-19-era
#27
JOURNAL ARTICLE
Seungwan Eun, Hee Yoon, Soo Yeon Kang, Ik Joon Jo, Sejin Heo, Hansol Chang, Guntak Lee, Jong Eun Park, Taerim Kim, Se Uk Lee, Sung Yeon Hwang, Sun-Young Baek
This study aimed to compare the accuracy of real-time trans-tracheal ultrasound (TTUS) with capnography to confirm intubation in cardiopulmonary resuscitation (CPR) while wearing a powered air-purifying respirator (PAPR). This setting reflects increased caution due to contagious diseases. This single-center, prospective, comparative study enrolled patients requiring CPR while wearing a PAPR who visited the emergency department of a tertiary medical center from December 2020 to August 2022. A physician performed the TTUS in real time and recorded the tube placement assessment...
January 21, 2024: Diagnostics
https://read.qxmd.com/read/38268847/the-association-of-regional-cerebral-oximetry-and-neurologically-intact-survival-in-a-porcine-model-of-cardiac-arrest
#28
JOURNAL ARTICLE
Mithun Suresh, Susana Arango, Johanna Moore, Bayert Salverda, Michael Lick, Carolina Rojas-Salvador, Anja Metzger, Guillaume Debaty, Pouria Pourzand, Alexander Kaizer, Keith Lurie
BACKGROUND: The objective of this study was to determine if regional cerebral oximetry (rSO2) assessed during CPR would be predictive of survival with favorable neurological function in a prolonged model of porcine cardiac arrest. This study also examined the relative predictive value of rSO2 and end-tidal carbon dioxide (ETCO2), separately and together. METHODS: This study is a post-hoc analysis of data from a previously published study that compared conventional CPR (C-CPR) and automated head-up positioning CPR (AHUP-CPR)...
March 2024: Resuscitation plus
https://read.qxmd.com/read/38252003/anesthesia-in-captive-giant-pandas-ailuropoda-melanoleuca-with-medetomidine-ketamine
#29
JOURNAL ARTICLE
Tim Bouts, Polly Taylor, Desheng Li, Frank Gasthuys, Alicia Quiévy, Stijn Schauvliege
One male and one female giant panda ( Ailuropoda melanoleuca ) from a Belgian zoo were anesthetized on eight different occasions over a course of 4 yr for electro-ejaculation ( n = 3) or artificial insemination ( n = 5). Medetomidine (0.03-0.04 mg/kg) and ketamine (2.5-3 mg/kg) were administered by intramuscular remote injection. Animals gained sternal recumbency with the loss of response to external stimuli after 4.9 ± 1.6 min (mean ± SD). The trachea was intubated with a 14-mm-internal diameter endotracheal tube; anesthesia was maintained with isoflurane in oxygen adjusted according to the required depth of anesthesia with a small-animal circle system...
January 2024: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://read.qxmd.com/read/38251288/effect-of-blood-flow-restriction-during-the-rest-periods-of-squats-on-accuracy-of-estimated-repetitions-to-failure
#30
JOURNAL ARTICLE
Daniel A Hackett, Boliang Wang, Derek L Tran
This study investigated the impact of resistance training with blood flow restriction during rest (BFRrest ) on the accuracy of estimated repetitions to failure (ERF). It also explored associations between error in ERF and mean concentric velocity (MCV) along with physiological responses. In a randomised cross-over study, 18 male trainers (23.4 ± 2.7 years) performed three sets of squats at 70% of their one-repetition maximum until failure. One session integrated BFRrest , while another employed traditional passive inter-set rest (TRAD) during the 3 min inter-set rest intervals...
December 31, 2023: Sports
https://read.qxmd.com/read/38249896/a-novel-method-for-the-bronchial-occlusion-of-prolonged-air-leakage-using-customized-endobronchial-plugs
#31
JOURNAL ARTICLE
Huihuang Lin, Yinfeng Wang, Daoqian Lu, Wencong Hong, Weide Wu, Duanhong Song, Huaping Zhang, Yiming Zeng
BACKGROUND: The management of prolonged air leakage (PAL) is a significant clinical challenge, particularly for patients who are unfit for surgical treatment. The use of endoscopic interventions with occlusive devices has been reported previously; however, local availability and cost may represent potential hurdles, especially in developing countries. In this study, we presented a conical endobronchial plug of our design and evaluated the efficacy of making use of that in the treatment of PAL as a novel method...
December 30, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/38249229/comparative-analysis-of-perfusion-index-and-end-tidal-carbon-dioxide-in-cardiac-arrest-patients-implications-for-hemodynamic-monitoring-and-resuscitation-outcomes
#32
JOURNAL ARTICLE
Baki Dogan, Emre Kudu, Faruk Danış, Elif Ozturk Ince, Mehmet A Karaca, Bulent Erbil
BACKGROUND: During cardiopulmonary resuscitation (CPR), some parameters (e.g., intraarterial pressure measurement and end-tidal carbon dioxide (EtCO2 )) indicate the quality and outcome of resuscitation. These parameters are generally based on monitoring the hemodynamic status. Perfusion index (PI) is a calculation from the photoplethysmography (PPG) signal and displays the proportion of pulsatile to non-pulsatile light absorption or reflection in the PPG signal. It helps to evaluate cardiac output and tissue perfusion in the care of a critical patient...
December 2023: Curēus
https://read.qxmd.com/read/38245339/10-min-exposure-to-a-2-5-hypercapnic-environment-increases-cerebral-blood-blow-but-does-not-impact-executive-function
#33
JOURNAL ARTICLE
Mustafa Shirzad, James Van Riesen, Nikan Behboodpour, Matthew Heath
Space travel and exploration are associated with increased ambient CO2 (i.e., a hypercapnic environment). Some work reported that the physiological changes (e.g., increased cerebral blood flow [CBF]) associated with a chronic hypercapnic environment contributes to a "space fog" that adversely impacts cognition and psychomotor performance, whereas other work reported no change or a positive change. Here, we employed the antisaccade task to evaluate whether transient exposure to a hypercapnic environment influences top-down executive function (EF)...
February 2024: Life Sciences in Space Research
https://read.qxmd.com/read/38241416/a-remote-controlled-automatic-chest-compression-device-capable-of-moving-compression-position-during-cpr-a-pilot-study-in-a-mannequin-and-a-swine-model-of-cardiac-arrest
#34
JOURNAL ARTICLE
Gil Joon Suh, Taegyun Kim, Kyung Su Kim, Woon Yong Kwon, Hayoung Kim, Heesu Park, Gaonsorae Wang, Jaeheung Park, Sungmoon Hur, Jaehoon Sim, Kyunghwan Kim, Jung Chan Lee, Dong Ah Shin, Woo Sang Cho, Byung Jun Kim, Soyoon Kwon, Ye Ji Lee
BACKGROUND: Recently, we developed a chest compression device that can move the chest compression position without interruption during CPR and be remotely controlled to minimize rescuer exposure to infectious diseases. The purpose of this study was to compare its performance with conventional mechanical CPR device in a mannequin and a swine model of cardiac arrest. MATERIALS AND METHODS: A prototype of a remote-controlled automatic chest compression device (ROSCER) that can change the chest compression position without interruption during CPR was developed, and its performance was compared with LUCAS 3 in a mannequin and a swine model of cardiac arrest...
2024: PloS One
https://read.qxmd.com/read/38200483/changes-in-lung-mechanics-and-ventilation-perfusion-match-comparison-of-pulmonary-air-and-thromboembolism-in-rats
#35
JOURNAL ARTICLE
József Tolnai, Bence Ballók, Roberta Südy, Álmos Schranc, Gabriella Varga, Barna Babik, Gergely H Fodor, Ferenc Peták
BACKGROUND: Pulmonary air embolism (AE) and thromboembolism lead to severe ventilation-perfusion defects. The spatial distribution of pulmonary perfusion dysfunctions differs substantially in the two pulmonary embolism pathologies, and the effects on respiratory mechanics, gas exchange, and ventilation-perfusion match have not been compared within a study. Therefore, we compared changes in indices reflecting airway and respiratory tissue mechanics, gas exchange, and capnography when pulmonary embolism was induced by venous injection of air as a model of gas embolism or by clamping the main pulmonary artery to mimic severe thromboembolism...
January 10, 2024: BMC Pulmonary Medicine
https://read.qxmd.com/read/38197786/modification-of-respiratory-drive-and-lung-stress-by-level-of-support-pressure-and-ecmo-sweep-gas-flow-in-patients-with-severe-covid-19-associated-acute-respiratory-distress-syndrome-an-exploratory-retrospective-analysis
#36
JOURNAL ARTICLE
Carolin Jung, Hans-Jörg Gillmann, Thomas Stueber
OBJECTIVES: Patients with severe acute respiratory distress syndrome (ARDS) often exhibit an unusually strong respiratory drive, which predisposes them to effort-induced lung injury. Careful titration of support pressure via the ventilator and carbon dioxide removal via extracorporeal membrane oxygenation (ECMO) may attenuate respiratory drive and lung stress. DESIGN: A retrospective cohort study. SETTING: At a single center, a university hospital...
January 2024: Journal of Cardiothoracic and Vascular Anesthesia
https://read.qxmd.com/read/38188554/a-novel-predictor-of-unsustained-return-of-spontaneous-circulation-in-cardiac-arrest-patients-through-a-combination-of-capnography-and-pulse-oximetry-a-multicenter-observational-study
#37
JOURNAL ARTICLE
Jing Yang, Hanqi Tang, Shihuan Shao, Feng Xu, Yangyang Fu, Shengyong Xu, Chen Li, Yan Li, Yang Liu, Joseph Harold Walline, Huadong Zhu, Yuguo Chen, Xuezhong Yu, Jun Xu
BACKGROUND: Unsustained return of spontaneous circulation (ROSC) is a critical barrier to survival in cardiac arrest patients. This study examined whether end-tidal carbon dioxide (ETCO2 ) and pulse oximetry photoplethysmogram (POP) parameters can be used to identify unsustained ROSC. METHODS: We conducted a multicenter observational prospective cohort study of consecutive patients with cardiac arrest from 2013 to 2014. Patients' general information, ETCO2 , and POP parameters were collected and statistically analyzed...
2024: World Journal of Emergency Medicine
https://read.qxmd.com/read/38185954/effects-of-haemodynamic-changes-caused-by-different-pneumoperitoneum-pressures-on-cerebral-oxygenation-in-laparoscopic-cholecystectomy-prospective-randomised-controlled-trial
#38
JOURNAL ARTICLE
Kivanc Oncu, Sedat Saylan
OBJECTIVE: To evaluate the role of different pneumoperitoneum pressure ranges on cerebral oxygenation. STUDY DESIGN: Prospective, randomised controlled trial. Place and Duration of the Study: Karadeniz Technical University, Turkiye, from January to September 2020. METHODOLOGY: Seventy patients (aged 18-65 years, ASA I-IIII) scheduled for laparoscopic cholecystectomy were divided into two groups; low pressure (LP, 10-12 mmHg) and high pressure (HP, 13-15 mmHg)...
January 2024: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://read.qxmd.com/read/38183063/impact-of-prone-position-on-dead-space-fraction-in-covid-19-related-acute-respiratory-distress-syndrome
#39
JOURNAL ARTICLE
Guillaume Théry, Astrée Scemama, Elvire Roblin, Morgan Caplan, Bruno Mourvillier, Antoine Goury
INTRODUCTION: COVID-19 Related Acute Respiratory Syndrome (C-ARDS) is characterized by a mismatch between respiratory mechanics and hypoxemia, suggesting increased dead-space fraction (DSF). Prone position is a cornerstone treatment of ARDS under invasive mechanical ventilation reducing mortality. We sought to investigate the impact of prone position on DSF in C-ARDS in a cohort of patients receiving invasive mechanical ventilation. METHODS: we retrospectively analysed data from 85 invasively mechanically ventilated patients with C-ARDS in supine and in prone positions, hospitalized in Intensive Care Unit (Reims University Hospital), between November, 1st 2020 and November, 1st 2022...
January 5, 2024: BMC Pulmonary Medicine
https://read.qxmd.com/read/38179881/hypoventilation-in-patients-with-prader-willi-syndrome-across-the-pediatric-age
#40
JOURNAL ARTICLE
Catherine Chen, Iulia Ioan, Marine Thieux, Marc Nicolino, Patricia Franco, Laurianne Coutier
OBJECTIVES: Few data on alveolar hypoventilation in Prader-Willi syndrome (PWS) are available and the respiratory follow-up of these patients is not standardized. The objectives of this study were to evaluate the prevalence of alveolar hypoventilation in children with PWS and identify potential risk factors. STUDY DESIGN: This retrospective study included children with PWS recorded by polysomnography (PSG) with transcutaneous carbon dioxide pressure (PtcCO2) or end-tidal CO2 (ETCO2) measurements, between 2007 and 2021, in a tertiary hospital center...
January 5, 2024: Pediatric Pulmonology
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