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https://www.readbyqxmd.com/read/28725787/nder-a-novel-web-application-for-teaching-histology-to-medical-students
#1
Elizabeth U Parker, Nicholas P Reder, Daniel Glasser, Jonathan Henriksen, Mark R Kilgore, Mara H Rendi
Medical students require a strong foundation in normal histology. However, current trends in medical school curricula have diminished time devoted to histology. Thus, there is a need for more efficient methods of teaching histology. We have developed a novel software program (Novel Diagnostic Educational Resource; https://pcs-webtest0.pathology.washington.edu/academics/pattern/) that uses annotated whole slide images to teach normal histology. Whole slide images of a wide variety of tissues were annotated by a trainee and validated by an experienced pathologist...
January 2017: Acad Pathol
https://www.readbyqxmd.com/read/28724699/early-career-researchers-an-interview-with-jeremy-goldbogen
#2
(no author information available yet)
Jeremy Goldbogen is an Assistant Professor at the Hopkins Marine Station, Stanford University, USA, where he studies the integrative biology of vertebrate filter feeders from forage fish to baleen whales. He received his Bachelor's degree in Zoology from the University of Texas, Austin, USA, before moving to the Scripps Institution of Oceanography and then the University of British Columbia for his PhD, which he completed in 2010 in the laboratory of Bob Shadwick. After a short postdoc at Scripps, Goldbogen moved to continue his postdoc training at the Cascadia Research Collective in Olympia, Washington...
July 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28723253/end-of-life-services-among-patients-with-cancer-evidence-from-cancer-registry-records-linked-with-commercial-health-insurance-claims
#3
Cara L McDermott, Catherine Fedorenko, Karma Kreizenbeck, Qin Sun, Bruce Smith, J Randall Curtis, Ted Conklin, Scott D Ramsey
PURPOSE: Despite guidelines emphasizing symptom management over aggressive treatment, end-of-life care for persons with cancer in the United States is highly variable. In consultation with a regional collaboration of patients, providers, and payers, we investigated indicators of high-quality end-of-life care to describe patterns of care, identify areas for improvement, and inform future interventions to enhance end-of-life care for patients with cancer. METHODS: We linked insurance claims to clinical information from the western Washington SEER database...
July 19, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28722299/cost-and-health-care-utilization-implications-of-bariatric-surgery-versus-intensive-lifestyle-and-medical-intervention-for-type-2-diabetes
#4
Souvik Banerjee, Louis P Garrison, David R Flum, David E Arterburn
OBJECTIVE: The aim of this study was to compare the cost and health care utilization of patients with obesity and type 2 diabetes mellitus (T2DM) randomized into either Roux-en-Y gastric bypass (RYGB) surgery or an intensive lifestyle and medical intervention (ILMI). METHODS: This analysis (N = 745) is based on 2-year follow-up of a small randomized controlled trial (RCT); adult patients with obesity and T2DM were recruited between 2011 and 2012 from Kaiser Permanente Washington...
July 19, 2017: Obesity
https://www.readbyqxmd.com/read/28721034/readmission-after-copd-exacerbation-scale-determining-30-day-readmission-risk-for-copd-patients
#5
Christine Sm Lau, Brianna L Siracuse, Ronald S Chamberlain
BACKGROUND: COPD affects over 13 million Americans, and accounts for over half a million hospitalizations annually. The Hospital Readmission Reduction Program, established by the Affordable Care Act requires the Centers for Medicare and Medicaid Services to reduce payments to hospitals with excess readmissions for COPD as of 2015. This study sought to develop a predictive readmission scale to identify COPD patients at higher readmission risk. METHODS: Demographic and clinical data on 339,389 patients from New York and California (derivation cohort) and 258,113 patients from Washington and Florida (validation cohort) were abstracted from the State Inpatient Database (2006-2011), and the Readmission After COPD Exacerbation (RACE) Scale was developed to predict 30-day readmission risk...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28720636/a-listening-tour-conversations-about-obamacare-across-america-s-heartland
#6
Paul R Gordon
During my sabbatical, I rode my bike 3300 miles from Washington, DC, to Seattle, WA, in order to engage in dialog with people along the northern tier of America's heartland. Through informal and candid conversations with >100 people, I gained insights into attitudes and opinions about the Patient Protection and Affordable Care Act (Obamacare). The comments were overwhelmingly negative. In this reflective essay, I share some of the conversations I had and the insights I gained from this remarkable journey across our beautiful country...
July 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28717999/macro-and-microclimate-conditions-may-alter-grapevine-deacclimation-variation-in-thermal-amplitude-in-two-contrasting-wine-regions-from-north-and-south-america
#7
Francisco Gonzalez Antivilo, Rosalía Cristina Paz, Markus Keller, Roberto Borgo, Jorge Tognetti, Fidel Roig Juñent
Low temperature is a limiting factor that affects vineyard distribution globally. The level of cold hardiness acquired during the dormant season by Vitis sp. is crucial for winter survival. Most research published on this topic has been generated beyond 40° N latitude, where daily mean temperatures may attain injurious levels during the dormant season resulting in significant damage to vines and buds. Symptoms of cold injury have been identified in Mendoza (32-35° S latitude), a Southern Hemisphere wine region characterized by a high thermal amplitude, and warm winds during the dormant season...
July 17, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28717809/racial-differences-in-misclassification-of-healthy-eating-based-on-food-frequency-questionnaire-and-24-hour-dietary-recalls
#8
B Olendzki, E Procter-Gray, M F Magee, G Youssef, K Kane, L Churchill, J Ockene, W Li
OBJECTIVES: To examine the agreement in nutrient intake and alternate healthy eating indices (AHEI) between a self-administered Food Frequency Questionnaire (FFQ) and 24-hour recall (24HR) measurements of diet by race, among urban older women. DESIGN: Cross-sectional observational study. SETTING: Urban neighborhoods in Washington, DC, USA. PARTICIPANTS: Community-dwelling White and Black women aged 65 and older. MEASUREMENTS: In 2014 and 2015, 49 White and 44 Black older women were queried on diet using both FFQ and 24-hour recalls...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28715253/drug-helplines-and-adult-marijuana-users-an-assessment-in-washington-colorado-oregon-and-alaska
#9
Beatriz H Carlini, Sharon B Garrett
Drug helplines are well known and widely utilized resources for those seeking help with managing their substance use. We used "secret shoppers" to preliminarily assess the readiness of drug helplines in four states that legalized non-medical adult marijuana use to assist those seeking information and help for marijuana use. Eleven calls were placed to the helpline staff, where the secret shopper posed as an adult users of marijuana interested in decreasing their marijuana use and asked questions about cannabinoids and methods of marijuana consumption...
July 17, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28715105/a-simulation-based-approach-to-measuring-team-situational-awareness-in-emergency-medicine-a-multicenter-observational-study
#10
Elizabeth D Rosenman, Aurora J Dixon, Jessica M Webb, Sarah Brolliar, Simon J Golden, Kerin A Jones, Sachita Shah, James A Grand, Steve W J Kozlowski, Georgia T Chao, Rosemarie Fernandez
OBJECTIVES: Team situational awareness (TSA) is critical for effective teamwork and supports dynamic decision-making in unpredictable, time-pressured situations. Simulation provides a platform for developing and assessing TSA; but these efforts are limited by suboptimal measurement approaches. The objective of this study was to develop and evaluate a novel approach to TSA measurement in interprofessional emergency medicine teams. METHODS: We performed a multicenter, prospective, simulation-based observational study to evaluate an approach to TSA measurement...
July 17, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28714543/effect-of-psychosocial-distress-on-outcome-for-head-and-neck-cancer-patients-undergoing-radiation
#11
Allen M Chen, Sophia Hsu, Care Felix, Jordan Garst, Taeko Yoshizaki
OBJECTIVES/HYPOTHESIS: To determine the impact of pretreatment psychosocial distress on compliance to radiation therapy (RT) and clinical outcomes for patients with head and neck cancer STUDY DESIGN: Self-reported responses to the mood and anxiety domains of the University of Washington Quality of Life instrument were reviewed among 133 patients with newly diagnosed head and neck cancer prior to initiating RT. METHODS: Varying definitions were used (total number of unexpectedly missed RT days, >5 days continuous interruption of RT outside of weekends, >10 days continuous interruption of RT, and failure to complete prescribed course of RT) to analyze the effect of psychosocial disruption on compliance...
July 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28713170/sexual-behaviour-in-early-adolescence-a-cross-national-comparison-of-australian-and-united-states-youth
#12
Laura E Prendergast, Rachel Leung, John W Toumbourou, Angela Taft, Barbara J McMorris, Richard F Catalano
OBJECTIVE: This study used matched samples from schools in the states of Victoria, Australia and Washington, United States (US), to compare sexual behaviour in early adolescence. It was hypothesised that the contrasting dominant policy objectives of harm minimisation in Australia and abstinence in the US would result in state differences for markers of sexual risk, mirroring prior cross-national findings in substance use. METHOD: A two-stage cluster sampling approach was used to recruit students from the two states...
March 2017: Australian Journal of Psychology
https://www.readbyqxmd.com/read/28710906/upward-drift-in-cerebrospinal-fluid-amyloid-%C3%AE-42-assay-values-for-more-than-10%C3%A2-years
#13
Suzanne E Schindler, Courtney L Sutphen, Charlotte Teunissen, Lena M McCue, John C Morris, David M Holtzman, Sandra D Mulder, Philip Scheltens, Chengjie Xiong, Anne M Fagan
INTRODUCTION: The best-established cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease are levels of amyloid-β 42 (Aβ42), total tau (tau), and phosphorylated tau 181 (ptau). We examined whether a widely used commercial immunoassay for CSF Aβ42, tau, and ptau provided stable measurements for more than ∼10 years. METHODS: INNOTEST assay values for CSF Aβ42, tau, and ptau from Washington University in St. Louis and VU Medical Center, Amsterdam, were evaluated...
July 12, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/28710493/-greater-good-versus-civil-liberties-in-the-united-states-tuberculosis-and-seattle-s-firland-sanatorium
#14
Christine Crudo Blackburn
As far back as the late 1700s, peoples in the United States were developing ways to control infectious disease without infringing on Constitutional rights. Despite acknowledgement that an infected person has certain civil liberties, the history of public health law shows that, in many instances, infectious disease isolation and quarantine proved to be scientifically questionable at best. I examine an historical example of such questionable relationship between public health and civil liberties: the locked ward at Firland Sanatorium in Seattle, Washington...
July 14, 2017: Journal of Public Health Policy
https://www.readbyqxmd.com/read/28707570/using-event-related-potentials-to-inform-the-neurocognitive-processes-underlying-knowledge-extension-through-memory-integration
#15
Nicole L Varga, Patricia J Bauer
To build a general knowledge base, it is imperative that individuals acquire, integrate, and further extend knowledge across experiences. For instance, in one episode an individual may learn that George Washington was the first president. In a separate episode he or she may then learn that Washington was the commander of the Continental Army. Integration of the information in memory may then support self-derivation of the new knowledge that the leader of the Continental Army was also the first president. Despite a considerable amount of fMRI research aimed at further elucidating the neuroanatomical regions supporting this ability, a consensus has yet to be reached with regards to the precise neurocognitive processes involved...
July 14, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/28707098/creating-environments-to-support-breastfeeding-the-challenges-and-facilitators-of-policy-development-in-hospitals-clinics-early-care-and-education-and-worksites
#16
Victoria A Bradford, Lina P Walkinshaw, Lesley Steinman, Jennifer J Otten, Kari Fisher, Amy Ellings, Jean O'Leary, Donna B Johnson
Objectives Supportive organizational breastfeeding policies can establish enabling environments for breastfeeding. In this qualitative study we identify facilitators and barriers to the development, adoption, and implementation of supportive breastfeeding policies and practices in four influential sectors for breastfeeding women: hospitals, clinics, early care and education settings, and worksites. Methods We interviewed 125 individuals representing 110 organizations in Washington State about their breastfeeding policy development and implementation process between August 2014 and February 2015...
July 13, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28705184/prevalence-of-gestational-diabetes-mellitus-based-on-various-screening-strategies-in-western-kenya-a-prospective-comparison-of-point-of-care-diagnostic-methods
#17
Sonak D Pastakia, Benson Njuguna, Beryl Ajwang' Onyango, Sierra Washington, Astrid Christoffersen-Deb, Wycliffe K Kosgei, Ponnusamy Saravanan
BACKGROUND: Early diagnosis of gestational diabetes mellitus (GDM) is crucial to prevent short term delivery risks and long term effects such as cardiovascular and metabolic diseases in the mother and infant. Diagnosing GDM in Sub-Saharan Africa (SSA) however, remains sub-optimal due to associated logistical and cost barriers for resource-constrained populations. A cost-effective strategy to screen for GDM in such settings are therefore urgently required. We conducted this study to determine the prevalence of gestational diabetes mellitus (GDM) and assess utility of various GDM point of care (POC) screening strategies in a resource-constrained setting...
July 14, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28704348/quickstats-age-adjusted-alzheimer-s-disease-death-rates-%C3%A2-among-persons-aged-%C3%A2-65-years-by-state-%C3%A2-united-states-2015
#18
(no author information available yet)
In 2015, the age-adjusted Alzheimer's disease death rate among persons aged ≥65 years in the United States was 231.0 per 100,000 population. The five states with the highest age-adjusted death rates for Alzheimer's disease were South Carolina (362.8), Washington (349.6), Mississippi (346.5), Tennessee (340.8), and Louisiana (333.6). New York had the lowest rate (99.0), followed by Maryland (128.2), Alaska (131.7), Connecticut (149.3), and the District of Columbia (152.2).
July 14, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28702890/adiposity-during-early-adulthood-changes-in-adiposity-during-adulthood-attained-adiposity-and-mammographic-density-among-premenopausal-women
#19
Aliya Alimujiang, Catherine Appleton, Graham A Colditz, Adetunji T Toriola
PURPOSE: We investigated the associations of adolescent adiposity, changes in adiposity during adulthood, and attained adiposity with volumetric mammographic density measures. METHODS: We recruited 383 premenopausal women who had a routine screening mammogram at the Breast Health Center, Washington University in St. Louis, MO from December 2015 to October 2016. Trained research personnel assessed current adiposity measures. Weight at ages 18 and 30 were self-reported...
July 12, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28702783/origins-of-life-research-a-bibliometric-approach
#20
Arsev Umur Aydinoglu, Zehra Taşkın
This study explores the collaborative nature and interdisciplinarity of the origin(s) of life (OoL) research community. Although OoL research is one of the oldest topics in philosophy, religion, and science; to date there has been no review of the field utilizing bibliometric measures. A dataset of 5647 publications that are tagged as OoL, astrobiology, exobiology, and prebiotic chemistry is analyzed. The most prolific authors (Raulin, Ehrenfreund, McKay, Cleaves, Cockell, Lazcano, etc.), most cited scholars and their articles (Miller 1953, Gilbert 1986, Chyba & Sagan 1992, Wȁchtershȁuser 1988, etc...
July 13, 2017: Origins of Life and Evolution of the Biosphere
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