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David M Fisher, Spencer A Wood, Eric M White, Dale J Blahna, Sarah Lange, Alex Weinberg, Michael Tomco, Emilia Lia
Outdoor recreation is one of many important benefits provided by public lands. Data on recreational use are critical for informing management of recreation resources, however, managers often lack actionable information on visitor use for large protected areas that lack controlled access points. The purpose of this study is to explore the potential for social media data (e.g., geotagged images shared on Flickr and trip reports shared on a hiking forum) to provide land managers with useful measures of recreational use to dispersed areas, and to provide lessons learned from comparing several more traditional counting methods...
June 13, 2018: Journal of Environmental Management
Yash A Choksi, Vishruth K Reddy, Kshipra Singh, Caitlyn W Barrett, Sarah P Short, Bobak Parang, Cody E Keating, Joshua J Thompson, Thomas G Verriere, Rachel E Brown, M Blanca Piazuelo, David M Bader, M Kay Washington, Mukul K Mittal, Thomas Brand, Alain P Gobert, Lori A Coburn, Keith T Wilson, Christopher S Williams
Blood vessel epicardial substance (BVES), or POPDC1, is a tight junction-associated transmembrane protein that modulates epithelial-to-mesenchymal transition (EMT) via junctional signaling pathways. There have been no in vivo studies investigating the role of BVES in colitis. We hypothesized that BVES is critical for maintaining colonic epithelial integrity. At baseline, Bves -/- mouse colons demonstrate increased crypt height, elevated proliferation, decreased apoptosis, altered intestinal lineage allocation, and dysregulation of tight junctions with functional deficits in permeability and altered intestinal immunity...
June 15, 2018: Mucosal Immunology
Arjun Sharma, Priyanka Govindan, Mirna Toukatly, Jack Healy, Connor Henry, Steve Senter, Behzad Najafian, Bryan Kestenbaum
BACKGROUND AND OBJECTIVES: AA-type kidney amyloidosis is classically associated with chronic autoimmune or inflammatory disorders. However, some urban centers have reported a high prevalence of injection drug use among patients with kidney AA amyloidosis. Previous reports lack control groups to quantify associations and most predate the opioid epidemic in the United States. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a case-control study of 38 patients with biopsy-confirmed kidney AA amyloidosis and 72 matched control individuals without this condition from two large hospital systems in Seattle, Washington...
June 15, 2018: Clinical Journal of the American Society of Nephrology: CJASN
S Lekishvili, B Chayen, S Chayen
The aim of the study was to compare and research: the general prevalence of DM in the Sumy region compared with the prevalence of DM in the whole of Ukraine during the years 2011-2016; the prevalence of ocular complications of diabetes and their tendency to progress in Ukraine and Sumy region over this period; various demographical traits of the prevalence of ocular complications of diabetes and the dependence of prevalence of ocular complications of diabetes upon environmental causes and various socio-economic factors...
May 2018: Georgian Medical News
Philip E Dubé, Cambrian Y Liu, Nandini Girish, M Kay Washington, D Brent Polk
Current treatments for inflammatory bowel disease (IBD) target the overactive immune response of the intestinal mucosa. However, epidermal growth factor (EGF), an activating ligand of the EGF receptor (EGFR), has been shown to induce disease remission through direct targeting of intestinal mucosal healing. Despite promising preclinical and clinical results, this EGFR-activating therapy has not progressed, in part due to the potential for carcinogenesis associated with long-term use and the increased risk of colitis-associated cancer (CAC) in IBD...
June 14, 2018: Scientific Reports
(no author information available yet)
Simon Sponberg is an Assistant Professor at the Georgia Institute of Technology, USA, where he studies neuromechanics and locomotor control. He received his joint honours Bachelor's degree in Biology and Physics from Lewis and Clark College, USA, in 2002 before moving to complete his PhD with Bob Full at the University of California, Berkeley, USA. He then completed a postdoc at the University of Washington, USA, with Tom Daniel and Adrienne Fairhall. Simon won a Young Investigator Award from the International Society for Neuroethology in 2014...
June 14, 2018: Journal of Experimental Biology
Maíra Sales Castilho, Sheila Canevese Rahal, Luciane Dos Reis Mesquita, Ramiro das Neves Dias Neto, Renato Tavares Conceição, Ana Luiza Denes, Washington Takashi Kano, Carlos Roberto Padovani, Alessandra Melchert
  This study aimed to assess joint angle values in the forelimbs and hind limbs of crab-eating foxes ( Cerdocyon thous) using a conventional manual goniometer. Nine captive crab-eating foxes, aged over 1 yr old, weighing from 5.9 to 7.5 kg were used. The maximum flexion and maximum extension of the shoulder, elbow, carpal, hip, stifle, and tarsal joints were measured. The range of motion was determined through the difference between the maximum flexion and the maximum extension. There was no significant difference between the right and left sides in the goniometric measurements...
June 2018: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
Torey M Anderson, Kaitlynn L McKirgan, Jennifer D Hastings
Study design: The primary study design was a pretest and posttest study performed in a single session with subjects as their own control. We summarize three integrated and sequential studies. Objective: The objective of this study was to investigate whether commercially available cushioned shorts would add skin protection when used in adaptive sports equipment (AE). Setting: Community in Tacoma Washington, USA. Methods: TekScan Pressure Mapping System for recording average (AP) and peak (PP) seating pressures...
2018: Spinal Cord Series and Cases
Lois James, Natalie Todak
OBJECTIVES: To examine the prevalence of Post-Traumatic Stress Disorder (PTSD) in a sample of prison employees, investigate risk factors, and explore protective factors for PTSD. METHODS: We surveyed 355 Washington State Department of Corrections employees. The survey included the PTSD checklist for the DSM-5 (PCL-5), the Critical Incident History Questionnaire, and the Work Environment Inventory. RESULTS: We found 19% of the sample met the criteria for diagnosable PTSD...
June 12, 2018: American Journal of Industrial Medicine
Catherine H Gowan, Shiba P Kar, Patricia A Townsend
This article contains survey data on Washington State landowner perceptions of bioenergy crops. The survey data includes responses on interest in growing bioenergy crops, likelihood of growing bioenergy crops, and willingness to grow hybrid poplar specifically for bioenergy. Additional responses concern challenges to growing hybrid poplar for bioenergy and preferences for growing hybrid poplar versus other bioenergy crops. The data contains on farm information, landowner demographics, current crops and cropping decisions, and perceptions of perennial crops as well...
June 2018: Data in Brief
Marcel W M Post, Jacinthe J E Adriaansen, Claudio Peter
STUDY DESIGN: Cross-sectional psychometric study. OBJECTIVES: The University of Washington Self-Efficacy Scale (UW-SES) is a measure of self-efficacy regarding managing challenges related to multiple sclerosis or spinal cord injury (SCI) that can be used across disabling conditions. The objective of this study was to examine the psychometric properties of its short form, the UW-SES-6, using the Rasch model. SETTING: Community, The Netherlands...
June 12, 2018: Spinal Cord
Thespina Yamanis, Mannat Malik, Ana María Del Río-González, Andrea L Wirtz, Erin Cooney, Maren Lujan, Ruby Corado, Tonia Poteat
Latina transgender women (LTW) are disproportionately vulnerable to depression, although the role of immigration/documentation status (legal authority to live/work in the U.S.) in depression has not been explored. LTW in Washington, DC were recruited into a cross-sectional study via convenience sampling. Most were Spanish-speaking Central American immigrants. Participants completed rapid HIV tests, and a Spanish-language survey assessing recent depressive symptoms (PHQ-2), sociodemographics, and factors from the minority stress framework: structural stressors (documentation status, stable housing), social stressors (discrimination, fear of deportation, violence) and coping resources (social support, resilience)...
June 12, 2018: International Journal of Environmental Research and Public Health
Lauren E Stewart, Michelle A Eston, Rebecca G Symons, Michael F Fialkow, Anna C Kirby
OBJECTIVES: Mesh midurethral slings (MUSs) are safe, effective treatments for female stress urinary incontinence (SUI), but many companies have ceased production because of controversies surrounding transvaginal mesh. To determine if introduction of MUS has increased the complication rate associated with SUI surgery, we compared women undergoing SUI surgery in the MUS era to those who had surgery prior its introduction. METHODS: This was a retrospective cohort study of a statewide hospital discharge database...
June 12, 2018: Female Pelvic Medicine & Reconstructive Surgery
Crystal E Brown, Ruth A Engelberg, Rashmi Sharma, Lois Downey, James A Fausto, James Sibley, William Lober, Nita Khandelwal, Elizabeth T Loggers, J Randall Curtis
BACKGROUND: Although racial/ethnic minorities receive more intense, nonbeneficial healthcare at the end of life, the role of race/ethnicity independent of other social determinants of health is not well understood. OBJECTIVES: Examine the association between race/ethnicity, other key social determinants of health, and healthcare intensity in the last 30 days of life for those with chronic, life-limiting illness. SUBJECTS: We identified 22,068 decedents with chronic illness cared for at a single healthcare system in Washington State who died between 2010 and 2015 and linked electronic health records to death certificate data...
June 12, 2018: Journal of Palliative Medicine
Lilia Y Kucheryavykh, Yuriy V Kucheryavykh, A Valance Washington, Mikhail Y Inyushin
While it is known that amyloid beta (Aβ) deposits are found in different tissues of both Alzheimer’s disease (AD) patients and healthy individuals, there remain questions about the physiological role of these deposits, the origin of the Aβ peptide, and the mechanisms of its localization to the tissues. Using immunostaining with specific antibodies, as well as enzyme-linked immunosorbent assay, this study demonstrated Aβ40 peptide accumulation in the skin during local experimental photothrombosis in mice...
June 8, 2018: International Journal of Molecular Sciences
Nazibrola Chitadze, Nino Gureshidze, Nino Rostiaschvili, Nargiza Danelia, Ketevan Dalakishvili, Liana Durglishvili, Revas Kuchukhidze, Paata Imnadze, Rusudan Chlikadze, Medea Betashvili, Tinatin Kuchuloria, Nino Akhvlediani, Robert Rivard, Mikeljon Nikolich, Christian T Bautista, Michael A Washington, Nino Akhvlediani
Military personnel are at an increased risk for exposure to arthropod- borne and zoonotic pathogens. The prevalence of these pathogens has not been adequately described in the country of Georgia. As the Georgian military moves toward an increased level of capability and the adoption of European Union and North Atlantic Treaty Organization standards, international field exercises will become more frequent and will likely involve an increasing number of international partners. This study was undertaken with the goal of defining the arthropod-borne and zoonotic pathogen threat in Georgia so force health protection planning can proceed in a rational and data-driven manner...
2018: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
Wee L Yee
Western cherry fruit fly, Rhagoletis indifferens Curran (Diptera: Tephritidae), is a quarantine pest of cherries (Prunus spp.) in western North America that can be detected using sticky yellow rectangle traps. Recently, a related invasive fly from Europe and Asia, the European cherry fruit fly, Rhagoletis cerasi (L.) (Diptera: Tephritidae), was detected in eastern North America, prompting surveys for it in the West. Sticky crossed-panel yellow Rebell and cylindrical-type yellow PALz traps were developed for R...
May 1, 2018: Journal of Insect Science
Elizabeth Gyllstrom, Kimberly Gearin, Donald Nease, Betty Bekemeier, Rebekah Pratt
OBJECTIVE: To describe the degree of public health and primary care collaboration at the local level and develop a model framework of collaboration, the Community Collaboration Health Model (CCHM). DESIGN: Mixed-methods, cross-sectional surveys, and semistructured, key informant interviews. SETTING: All local health jurisdictions in Colorado, Minnesota, Washington, and Wisconsin. PARTICIPANTS: Leaders from each jurisdiction were identified to describe local collaboration...
June 7, 2018: Journal of Public Health Management and Practice: JPHMP
Kimberly K Repp, Eva Hawes, Kathleen J Rees, Beth Vorderstrasse, Sue Mohnkern
CONTEXT: Conducting a large-scale Community Assessment for Public Health Emergency Response (CASPER) in a geographically and linguistically diverse county presents significant methodological challenges that require advance planning. PROGRAM: The Centers for Disease Control and Prevention (CDC) has adapted methodology and provided a toolkit for a rapid needs assessment after a disaster. The assessment provides representative data of the sampling frame to help guide effective distribution of resources...
June 7, 2018: Journal of Public Health Management and Practice: JPHMP
Madeline C Frost, Emily C Williams, Susan Kingston, Caleb J Banta-Green
OBJECTIVES: Opioid use is a growing problem in the United States. Despite existence of effective treatments (eg, opioid agonist medication), most people with opioid use disorder do not receive treatment. Increasing treatment receipt is an essential component of the response to the opioid crisis. We examined factors associated with interest in getting help to reduce or stop substance use among syringe exchange program (SEP) clients who reported using opioids. METHODS: Surveys were administered at 17 SEPs across Washington State during 2015; 436 respondents who reported recent opioid use and not receiving current treatment were eligible for this analysis...
June 7, 2018: Journal of Addiction Medicine
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