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https://www.readbyqxmd.com/read/29679148/scientific-session-of-the-16th-world-congress-of-endoscopic-surgery-jointly-hosted-by-society-of-american-gastrointestinal-and-endoscopic-surgeons-sages-canadian-association-of-general-surgeons-cags-seattle-washington-usa-11-14-april-2018-poster-abstracts
#1
https://www.readbyqxmd.com/read/29678432/effects-of-shame-and-guilt-on-error-reporting-among-obstetric-clinicians
#2
Mara Lynne Zabari, Nancy L Southern
OBJECTIVE: To understand how the experiences of shame and guilt, coupled with organizational factors, affect error reporting by obstetric clinicians. DESIGN: Descriptive cross-sectional. SETTING AND PARTICIPANTS: A sample of 84 obstetric clinicians from three maternity units in Washington State. METHODS: In this quantitative inquiry, a variant of the Test of Self-Conscious Affect was used to measure proneness to guilt and shame...
April 17, 2018: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/29673188/novel-chlorhexidine-loaded-polymeric-nanoparticles-for-root-canal-treatment
#3
Gina Quiram, Francisco Montagner, Kelli L Palmer, Mihaela C Stefan, Katherine E Washington, Danieli C Rodrigues
Persistence of microorganisms in dentinal tubules after root canal chemo-mechanical preparation has been well documented. The complex anatomy of the root canal and dentinal buffering ability make delivery of antimicrobial agents difficult. This work explores the use of a novel trilayered nanoparticle (TNP) drug delivery system that encapsulates chlorhexidine digluconate, which is aimed at improving the disinfection of the root canal system. Chlorhexidine digluconate was encapsulated inside polymeric self-assembled TNPs...
April 17, 2018: Journal of Functional Biomaterials
https://www.readbyqxmd.com/read/29672676/a-trial-of-a-single-tablet-regimen-of-elvitegravir-cobicistat-emtricitabine-and-tenofovir-disoproxil-fumarate-for-the-initial-treatment-of-hiv-2-infection-in-a-resource-limited-setting-48-week-results-from-senegal-west-africa
#4
Selly Ba, Dana N Raugi, Robert A Smith, Fatima Sall, Khadim Faye, Stephen E Hawes, Papa Salif Sow, Moussa Seydi, Geoffrey S Gottlieb
Background: There is an urgent need for safe and effective ART for HIV-2 infection. We undertook the first clinical trial of a single-tablet-regimen containing elvitegravir-cobicistat-emtricitabine-tenofovir disoproxil fumarate (E/C/F/TDF) to assess its effectiveness in HIV-2-infected individuals in Senegal, West Africa. Methods: HIV-2-infected, ART-naïve adults with WHO stage 3-4 disease or CD4 counts below 750 cells/mm3 were eligible for this 48 week, open-label trial...
April 17, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29672143/adolescent-age-of-sexual-initiation-and-subsequent-adult-health-outcomes
#5
Marina Epstein, Madeline Furlong, Rick Kosterman, Jennifer A Bailey, Kevin M King, Sara A Vasilenko, Christine M Steeger, Karl G Hill
OBJECTIVES: To examine the mechanisms of the association between age of sexual initiation and adult health. METHODS: Data from the Seattle Social Development Project (n = 808), in Seattle, Washington, included outcomes when participants were in their 30s (2005-2014): substance use disorders, depression, poor health, and obesity. Sexual consequence mediators included sexually transmitted infection, adolescent pregnancy, and a high number of sexual partners. We used linear logistic regression to model main effect and mediated associations...
April 19, 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29671837/analysis-of-17-genes-detects-mutations-in-81-of-811-patients-with-lissencephaly
#6
Nataliya Di Donato, Andrew E Timms, Kimberly A Aldinger, Ghayda M Mirzaa, James T Bennett, Sarah Collins, Carissa Olds, Davide Mei, Sara Chiari, Gemma Carvill, Candace T Myers, Jean-Baptiste Rivière, Maha S Zaki, Joseph G Gleeson, Andreas Rump, Valerio Conti, Elena Parrini, M Elizabeth Ross, David H Ledbetter, Renzo Guerrini, William B Dobyns
PurposeTo estimate diagnostic yield and genotype-phenotype correlations in a cohort of 811 patients with lissencephaly or subcortical band heterotopia.MethodsWe collected DNA from 756 children with lissencephaly over 30 years. Many were tested for deletion 17p13.3 and mutations of LIS1, DCX, and ARX, but few other genes. Among those tested, 216 remained unsolved and were tested by a targeted panel of 17 genes (ACTB, ACTG1, ARX, CRADD, DCX, LIS1, TUBA1A, TUBA8, TUBB2B, TUBB, TUBB3, TUBG1, KIF2A, KIF5C, DYNC1H1, RELN, and VLDLR) or by whole-exome sequencing...
April 19, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29670758/remote-biomonitoring-of-temperatures-in-mothers-and-newborns-design-development-and-testing-of-a-wearable-sensor-device-in-a-tertiary-care-hospital-in-southern-india
#7
Prem K Mony, Prashanth Thankachan, Swarnarekha Bhat, Suman Rao, Maryann Washington, Sumi Antony, Annamma Thomas, Sheela C Nagarajarao, Hiteshwar Rao, Bharadwaj Amrutur
Objective: Newer technologies such as wearables, sensors, mobile telephony and computing offer opportunities to monitor vital physiological parameters and tackle healthcare problems, thereby improving access and quality of care. We describe the design, development and testing of a wearable sensor device for remote biomonitoring of body temperatures in mothers and newborns in southern India. Methods: Based on client needs and technological requirements, a wearable sensor device was designed and developed using principles of 'social innovation' design...
April 2018: BMJ Innovations
https://www.readbyqxmd.com/read/29670391/determining-30-day-readmission-risk-for-heart-failure-patients-the-readmission-after-heart-failure-scale
#8
Ronald S Chamberlain, Jaswinder Sond, Krishnaraj Mahendraraj, Christine Sm Lau, Brianna L Siracuse
Background: Chronic heart failure (CHF), which affects >5 million Americans, accounts for >1 million hospitalizations annually. As a part of the Hospital Readmission Reduction Program, the Affordable Care Act requires that the Centers for Medicare and Medicaid Services reduce payments to hospitals with excess readmissions. This study sought to develop a scale that reliably predicts readmission rates among patients with CHF. Methods: The State Inpatient Database (2006-2011) was utilized, and discharge data including demographic and clinical characteristics on 642,448 patients with CHF from California and New York (derivation cohort) and 365,359 patients with CHF from Florida and Washington (validation cohort) were extracted...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29669892/wing-scale-ultrastructure-underlying-convergent-and-divergent-iridescent-colours-in-mimetic-heliconius-butterflies
#9
Andrew J Parnell, James E Bradford, Emma V Curran, Adam L Washington, Gracie Adams, Melanie N Brien, Stephanie L Burg, Carlos Morochz, J Patrick A Fairclough, Pete Vukusic, Simon J Martin, Scott Doak, Nicola J Nadeau
Iridescence is an optical phenomenon whereby colour changes with the illumination and viewing angle. It can be produced by thin film interference or diffraction. Iridescent optical structures are fairly common in nature, but relatively little is known about their production or evolution. Here we describe the structures responsible for producing blue-green iridescent colour in Heliconius butterflies. Overall the wing scale structures of iridescent and non-iridescent Heliconius species are very similar, both having longitudinal ridges joined by cross-ribs...
April 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29669818/changes-in-glomerular-filtration-rate-and-impact-on-long-term-survival-among-adults-after-hematopoietic-cell-transplantation-a-prospective-cohort-study
#10
Sangeeta Hingorani, Emily Pao, Phil Stevenson, Gary Schoch, Benjamin L Laskin, Ted Gooley, George B McDonald
BACKGROUND AND OBJECTIVES: Kidney injury is a significant complication for patients undergoing hematopoietic cell transplantation (HCT), but few studies have prospectively examined changes in GFR in long-term survivors of HCT. We described the association between changes in GFR and all-cause mortality in patients up to 10 years after HCT. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a prospective, observational cohort study of adult patients undergoing HCT at the Fred Hutchinson Cancer Center in Seattle, Washington from 2003 to 2015...
April 18, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29669529/improving-quality-of-life-through-the-routine-use-of-the-patient-concerns-inventory-for-head-and-neck-cancer-patients-a-cluster-preference-randomized-controlled-trial
#11
Simon N Rogers, Derek Lowe, Cher Lowies, Seow Tien Yeo, Christine Allmark, Dominic Mcavery, Gerald M Humphris, Robert Flavel, Cherith Semple, Steven J Thomas, Anastasios Kanatas
BACKGROUND: The consequences of treatment for Head and Neck cancer (HNC) patients has profound detrimental impacts such as impaired QOL, emotional distress, delayed recovery and frequent use of healthcare. The aim of this trial is to determine if the routine use of the Patients Concerns Inventory (PCI) package in review clinics during the first year following treatment can improve overall quality of life, reduce the social-emotional impact of cancer and reduce levels of distress. Furthermore, we aim to describe the economic costs and benefits of using the PCI...
April 18, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29669423/using-a-retention-in-care-protocol-to-promote-positive-health-and-systems-related-outcomes
#12
Alfred A Larbi, Freya Spielberg, Nnemdi Kamanu Elias, Erin Athey, Ngozi Ogbuawa, Nancy Murphy
People living with HIV can experience the full benefits of retention when they are continuously engaged in care. Continuous engagement in care promotes improved adherence to ART and positive health outcomes. An infectious disease clinic has implemented a protocol to primarily improve patient retention. The retrospective, facility-based, costing study took place in an infectious disease clinic in Washington DC. Retention was defined in two ways and over a 12-month period. Micro-costing direct measurement methods were used to collect unit costs in time series...
April 18, 2018: AIDS Care
https://www.readbyqxmd.com/read/29669181/racial-disparity-in-oncologic-and-quality-of-life-outcomes-in-patients-with-locally-advanced-head-and-neck-squamous-cell-carcinomas-enrolled-in-a-randomized-phase-2-trial
#13
Margaret K Guerriero, Mary W Redman, Kelsey K Baker, Renato G Martins, Keith Eaton, Laura Q Chow, Rafael Santana-Davila, Christina Baik, Bernardo H Goulart, Sylvia Lee, Cristina P Rodriguez
BACKGROUND: To better understand patient-reported quality of life (PRQOL) for patients with head and neck cancer, PRQOL scores were collected in a clinical trial. METHODS: Patients were randomized to arm A (70 Gy of radiation with cisplatin) or arm B (70 Gy of radiation with cisplatin plus erlotinib at 150 mg daily). PRQOL scores were measured on days -7 (arm B only), 0, 30, and 180 with the University of Washington Quality of Life Questionnaire. Associations with clinical factors and outcomes were explored with linear mixed, logistic, and Cox regression models...
April 18, 2018: Cancer
https://www.readbyqxmd.com/read/29668650/impact-of-an-advanced-imaging-utilization-review-program-on-downstream-health-care-utilization-and-costs-for-low-back-pain
#14
Janessa M Graves, Deborah Fulton-Kehoe, Jeffrey G Jarvik, Gary M Franklin
BACKGROUND: Early magnetic resonance imaging (MRI) for acute low back pain (LBP) has been associated with increased costs, greater health care utilization, and longer disability duration in workers' compensation claimants. OBJECTIVES: To assess the impact of a state policy implemented in June 2010 that required prospective utilization review (UR) for early MRI among workers' compensation claimants with LBP. RESEARCH DESIGN: Interrupted time series...
April 17, 2018: Medical Care
https://www.readbyqxmd.com/read/29668646/choice-defines-qalys-a-us-valuation-of-the-eq-5d-5l
#15
Benjamin M Craig, Kim Rand
BACKGROUND: The 5-level version of the EQ-5D (EQ-5D-5L) was introduced as an improvement on the original 3-level version (EQ-5D-3L). To date, 6 country-specific value sets have been published for EQ-5D-5L and 9 US value sets have been published for other instruments. Our aims were to (1) produce EQ-5D-5L values on a quality-adjusted life year (QALY) scale from the perspective of US adults and (2) compare them with US EQ-5D-3L values and the other country-specific EQ-5D-5L values. METHODS: In 2016, 8222 US respondents from all 50 states and Washington, DC completed an online survey including a discrete choice experiment with 20 paired comparisons...
April 17, 2018: Medical Care
https://www.readbyqxmd.com/read/29668527/opioid-and-benzodiazepine-use-before-injury-among-workers-in-washington-state-2012-2015
#16
Esi W Nkyekyer, Deborah Fulton-Kehoe, June Spector, Gary Franklin
OBJECTIVE: To characterize pre-injury prescription opioid and benzodiazepine use and its relationship with post-injury use and missed work among workers. METHODS: 313,543 Washington State Department of Labor and Industries workers' compensation injury claims from 2012-2015 were linked with State Prescription Monitoring Program data. Pre-injury prevalence of opioid and benzodiazepine use were compared between compensable and non-compensable claims, and between workers with and without post-injury prescriptions, using the Pearson Chi-Square test...
April 17, 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29667280/grass-greenness-flush-can-influence-breeding-phenology-and-fertility-in-equatorial-thoroughbred-mares-in-the-absence-of-photoperiod-variation
#17
Juan Carranza, Washington A Yoong, Belén Caño Vergara, Abel Briones, Concha Mateos
Reproductive phenology is an important trait subjected to natural selection. Current horses in America belong to the Palearctic original populations after being introduced by European colonizers. Photoperiod variation is the main environmental factor for the adjustment of reproductive timing in horses, but is absent in equatorial areas. Here we hypothesize that seasonality of green-grass availability may influence breeding phenology in equatorial regions. We used data of 929 services to mares from 2006 to 2011 in a thoroughbred equine exploitation in Ecuador that experienced strong grass seasonality...
April 17, 2018: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/29667168/cognitive-decline-and-older-driver-crash-risk
#18
Laura A Fraade-Blanar, Beth E Ebel, Eric B Larson, Jeanne M Sears, Hilaire J Thompson, Kwun Chuen G Chan, Paul K Crane
OBJECTIVES: To examine automobile crash risk associated with cognition in older drivers without dementia. DESIGN: Retrospective secondary analysis of longitudinal cohort study. SETTING: Our study used data from the Adult Changes in Thought (ACT) Study merged with Washington State crash reports and licensure records. Data were available from 2002 to 2015. PARTICIPANTS: Group Health enrollees from Washington State aged 65 and older with active driver's licenses (N=2,615)...
April 17, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29666427/consistent-differences-in-fitness-traits-across-multiple-generations-of-olympia-oysters
#19
Katherine E Silliman, Tynan K Bowyer, Steven B Roberts
Adaptive evolution and plasticity are two mechanisms that facilitate phenotypic differences between populations living in different environments. Understanding which mechanism underlies variation in fitness-related traits is a crucial step in designing conservation and restoration management strategies for taxa at risk from anthropogenic stressors. Olympia oysters (Ostrea lurida) have received considerable attention with regard to restoration, however there is limited information on adaptive population structure...
April 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29665612/differences-in-segmental-speeds-as-a-function-of-maturation-in-youth-baseball-pitchers
#20
Jessica K Washington, Gabrielle G Gilmer, Jeff W Barfield, Sarah S Gascon, Michael G Saper, Jeffrey R Dugas, James R Andrews, Gretchen D Oliver
The purpose of this study was to determine how stride length, segmental sequencing of the pelvis, trunk, humerus, and forearm velocities and accelerations, and the timing of these values change as youth mature. Thirteen youth baseball pitchers participated at three consecutive time points: visit 1 (10.7±1.3 years; 151.8±10.7 cm; 45.0±9.65 kg), visit 2 (11.5±1.6 years; 155.5±11.1 cm; 50.4±10.0 kg), and visit 3 (12.4±1.7 years; 161.5±11.7 cm; 56.4±10.8 kg). Participants executed three pitches for a strike to a catcher...
April 17, 2018: International Journal of Sports Medicine
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