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https://www.readbyqxmd.com/read/29234719/compression-stockings-as-an-effective-treatment-for-erythema-nodosum-case-series
#1
K B Golisch, S P Gottesman, R J Segal
Erythema nodosum (EN) is a septal panniculitis that is characterized clinically by tender, erythematous, subcutaneous nodules that are predominately localized on the pretibial lower legs. EN affects women more than men and can be idiopathic or secondary to another disease process such as infection or an immune response. Treatment options for erythema nodosum are suboptimal and often involve significant side effects or require a change in lifestyle. We investigated the effects of moderate 20 mmHg to 30 mmHg compression stockings as an alternative treatment method in two female patients with recurrent erythema nodosum...
December 2017: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/29230861/an-uncommon-cause-of-panniculitis
#2
T King, R Rabindranathnambi, G S Van Schalkwyk
No abstract text is available yet for this article.
December 12, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29229575/anti-melanoma-differentiation-associated-gene-5-mda5-dermatomyositis-a-concise-review-with-an-emphasis-on-distinctive-clinical-features
#3
REVIEW
Drew Jb Kurtzman, Ruth Ann Vleugels
Melanoma differentiation-associated gene 5 (MDA5) is a recently described autoantigen target in a subset of patients with dermatomyositis (DM). Anti-MDA5 DM is characterized by a unique mucocutaneous and systemic phenotype that includes cutaneous and oral ulceration, painful palmar papules, alopecia, panniculitis, arthritis, a lower incidence of myositis, and, importantly, an elevated risk of interstitial lung disease, with a potentially fatal course. Because the clinical features may differ substantially from those typically observed in cutaneous DM, the diagnosis is often overlooked, which may negatively affect patient outcomes...
December 8, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29225784/diagnosing-alpha-1-antitrypsin-deficiency-the-first-step-in-precision-medicine
#4
REVIEW
Craig P Hersh
Severe alpha-1 antitrypsin (AAT) deficiency is one of the most common serious genetic diseases in adults of European descent. Individuals with AAT deficiency have a greatly increased risk for emphysema and liver disease. Other manifestations include bronchiectasis, necrotizing panniculitis and granulomatosis with polyangiitis. Despite the frequency and potential severity, AAT deficiency remains under-recognized, and there is often a delay in diagnosis. This review will focus on three recent updates that should serve to encourage testing and diagnosis of AAT deficiency: first, the publication of a randomized clinical trial demonstrating the efficacy of intravenous augmentation therapy in slowing the progression of emphysema in AAT deficiency; second, the mounting evidence showing an increased risk of lung disease in heterozygous PI MZ genotype carriers; last, the recent publication of a clinical practice guideline, outlining diagnosis and management...
2017: F1000Research
https://www.readbyqxmd.com/read/29222586/-misty-mesentery-mesenteric-panniculitis-and-associated-processes
#5
REVIEW
L P Beyer, A Schreyer
BACKGROUND: Sclerosing mesenteritis (SM) and mesenteric panniculitis are rare processes of the mesentery which pose a major clinical and imaging challenge. This review article attempts to introduce a systematic nomenclature to address typical symptoms, imaging and major differential diagnoses. RESULTS: SM with its subtypes-mesenteric lipodystrophy, panniculitis and retractile mesenteritis-is a chronic process with a very diverse and heterogeneous clinical appearance...
December 8, 2017: Der Radiologe
https://www.readbyqxmd.com/read/29199390/autoimmune-inflammatory-syndrome-induced-by-adjuvants-asia-related-to-biomaterials-analysis-of-45-cases-and-comprehensive-review-of-the-literature
#6
Jaume Alijotas-Reig, Enrique Esteve-Valverde, Natalia Gil-Aliberas, Victor Garcia-Gimenez
Systemic autoimmune or granulomatous disorders related to biomaterials of human use have rarely been described. The aim of this study was to report cases of autoimmune/inflammatory syndrome induced by adjuvants (ASIA) related to biomaterial injections and prostheses, mainly silicone, hyaluronic acid, acrylamides and methacrylate compounds in a Spanish patient cohort. This study is a retrospective analysis of clinical, laboratory, histopathological and follow-up data of 45 cases of patients suffering from late-onset, non-infectious inflammatory/autoimmune disorders related to bioimplants...
December 3, 2017: Immunologic Research
https://www.readbyqxmd.com/read/29189887/eosinophilic-granulomatosis-with-polyangiitis-without-respiratory-symptoms-or-asthma-in-an-adolescent-case-report-and-literature-review
#7
REVIEW
Gülçin Otar Yener, Zahide Ekici Tekin, Neşe Çallı Demirkan, Selçuk Yüksel
Eosinophilic granulomatosis with polyangiitis (EGPA), also known as Churg-Strauss syndrome, is a systemic necrotizing vasculitis of the small and medium vessels. It is primarily associated with respiratory conditions such as asthma and sinusitis as well as eosinophilia, neuropathy, pulmonary infiltrates, and vasculitis. EGPA is extremely rare in the pediatric age group, and respiratory system disorders are usually predominant in EGPA patients. A 14-year-old boy presented with rash and severe extremity pain...
November 30, 2017: Rheumatology International
https://www.readbyqxmd.com/read/29189695/lymphoma-involving-skin-and-subcutaneous-fat-of-the-breast-two-cases
#8
Miri Kwon, Eun Young Ko, Boo-Kyung Han, Young Hye Ko, Eun Yoon Cho, Soo Youn Cho, Shin Young Kim
Breast lymphoma is uncommon, and it usually involves breast parenchyma and ipsilateral axillary lymph nodes. We report rare cases of cutaneous T-cell lymphoma involving the skin and subcutaneous fat layers mimicking panniculitis of the breasts in a 33-year-old male patient who presented with a growing palpable mass and pain in both breasts and in 17-year-old female patient who presented with an indolent palpable breast mass for 1 year. Extranodal natural killer/T-cell nasal-type and subcutaneous panniculitis-like T-cell lymphomas were diagnosed after skin punch biopsies...
December 2017: Ultrasound Quarterly
https://www.readbyqxmd.com/read/29187665/-a-case-report-of-subcutaneous-panniculitis-like-t-cell-lymphoma-with-fever-and-erythema-on-the-body-as-the-initial-symptoms
#9
Yi Zhan, Peng Zhang, Fangfang Zhang, Qianjin Lu, Rong Xiao, Guiying Zhang
Subcutaneous panniculitis-like T cell lymphoma (SPTCL) is a very rare form of peripheral α/β T cell skin lymphoma that is localized primarily in the subcutaneous adipose tissues. It is characterized by single or multiple painful subcutaneous nodules or lumps, often affecting the limbs. The patient presented to the Department of Dermatology, Second Xiangya Hospital, Central South University, who suffered from intermittent fever and erythema on the body, finally was diagnosed as SPTCL after histopathological examinations for twice...
November 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/29171395/incidence-and-ten-year-follow-up-of-primary-cutaneous-lymphomas-a-single-centre-cohort-study
#10
Martina Maurelli, Gianpaolo Tessari, Chiara Colato, Donatella Schena, Giampiero Girolomoni
BACKGROUND: Primary cutaneous lymphomas (PCLs) are a rare group of extranodal non-Hodgkin lymphomas, and epidemiological data in Mediterranean countries are scarce. OBJECTIVE: To investigate the incidence and characteristics of PCL in a single tertiary referral centre in Italy. MATERIALS & METHODS: A total of 141 PCL patients, seen over a 10-year follow-up period, were investigated. RESULTS: Incidence rate of PCL was 0...
November 24, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/29167188/severe-panniculitis-and-polyarthritis-caused-by-acinar-cell-carcinoma-arising-from-an-ectopic-pancreas
#11
Marc Plier, Patrick Durez, Mina Komuta, Alexandros Raptis
The pancreatitis, panniculitis and polyarthritis (PPP) syndrome is a rare condition caused by pancreatic diseases, such as acute or chronic pancreatitis or pancreatic carcinoma. We report the first case of PPP syndrome caused by metastatic acinar cell carcinoma from an ectopic pancreas. The symptoms were successfully managed by the treatment of the metastatic carcinoma. Pancreatic cytosteatonecrosis should be always considered in a patient who is showing symptoms of panniculitis and polyarthritis.
November 21, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29145794/analysis-of-bacterial-and-fungal-nucleic-acid-in-canine-sterile-granulomatous-and-pyogranulomatous-dermatitis-and-panniculitis
#12
Fabio B Rosa, Caitlin E Older, Courtney Meason-Smith, Jan S Suchodolski, Sonia Lingsweiler, Joanne E Mansell, Aline Rodrigues Hoffmann
Next generation sequencing (NGS) studies are revealing a diverse microbiota on the skin of dogs. The skin microbiota of canine sterile granulomatous and pyogranulomatous dermatitis (SGPD) has yet to be investigated using NGS techniques. NGS targeting the 16S rRNA and ITS-1 region of bacterial and fungal DNA, respectively, were used to investigate if bacterial and fungal DNA were associated with skin lesions in cases of canine SGPD. The study included 20 formalin-fixed paraffin-embedded (FFPE) skin samples and 12 fresh samples from SGPD-affected dogs, and 10 FFPE and 10 fresh samples from healthy dogs...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/29145587/paradoxical-adipose-hypertrophy-pah-after-cryolipolysis
#13
Nathaniel Stroumza, Nelly Gauthier, Patricia Senet, Philippe Moguelet, Raphael Nail Barthelemy, Michael Atlan
Background: Cryolipolysis is a minimally invasive technique used to decrease local adipose tissue by thermal cooling. Paradoxical adipose hypertrophy (PAH) is a rare complication of cryolipolysis with important aesthetic consequences. Objectives: The objective of this study was to describe four cases of PAH after a cryolipolysis treatment. Methods: Between January 2014 and January 2017, all patients who had undergone a cryolipolysis treatment in a single center were reviewed...
November 14, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29110314/post-irradiation-morphoea-of-the-breast-a-case-report-and-review-of-the-literature
#14
Paula I Gonzalez-Ericsson, Monica V Estrada, Rami Al-Rohil, Melinda E Sanders
We describe a 44-year-old female with triple-negative breast cancer who developed skin erythaema, sclerosis and contracture of her entire right breast 15 months after completion of post-lumpectomy chemotherapy and radiotherapy, consistent with post-irradiation morphoea (PIM). PIM is a rare complication of breast irradiation that impairs a patient's quality of life. PIM is located usually at the radiation port or in the surrounding tissue. Clinically, PIM is misdiagnosed commonly as lymphoedema and cellulitis in the early inflammatory phase, and recurrent breast cancer, chronic radiodermatitis (CRD), radiation-induced fibrosis (RIF), post-irradiation pseudosclerodermatous panniculitis (PIPP), atypical vascular lesions (AVL) or angiosarcoma (AS) in the late burnout phase...
August 14, 2017: Histopathology
https://www.readbyqxmd.com/read/29082362/an-unexpected-etiology-of-pancreatic-panniculitis-a-case-report
#15
A C Evans, A D Singhi, H J Zeh, N Bahary, R E Brand
BACKGROUND: Pancreatic panniculitis is a rare cause of subcutaneous fat necrosis secondary to elevated serum levels of pancreatic enzymes. It is most often associated with pancreatic acinar cell carcinoma, but has also been seen in patients with pancreatitis. CASE REPORT: We present a case of a 64 year old Caucasian man without symptoms of pancreatitis who presents with pancreatic panniculitis manifesting in multiple subcutaneous ulcerating nodules of the bilateral lower extremities, discovered to have a previously unreported etiology for this condition...
2017: Journal of Pancreatic Cancer
https://www.readbyqxmd.com/read/29081476/sterile-nodular-panniculitis-with-lung-and-lymph-node-involvement-in-a-siberian-tiger-panthera-tigris-altica
#16
Shou-Ping Hu, Zhuo Zhang, Jiao-Er Zhang, Xue-Hui Cai, Hiroyuki Nakayama, Xi-Jun He
A 2- to 4-year-old uncastrated male Siberian tiger (Panthera tigris altica) bred in a local wild animal park presented with generalized clinical signs including abdominal pain, fever, lethargy, and anorexia, along with subcutaneous nodules along the trunk. The patient subsequently died of chronic, progressive dyspnea despite 45 days of antibiotic treatment. At necropsy, mesenteric fat inflammation and multiple subcutaneous, peritoneal, and intraabdominal nodules were observed. The lungs demonstrated congestion and heavy coagulation, and necrotic foci were observed on the cut surface...
October 30, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29073610/an-overlooked-potentially-treatable-disorder-idiopathic-mesenteric-panniculitis
#17
Abdurrahman Sahin, Hakan Artas, Yesim Eroglu, Nurettin Tunc, Ulvi Demirel, Ibrahim Halil Bahcecioglu, Mehmet Yalniz
OBJECTIVE: The aim of this study was to determine the prevalence of mesenteric panniculitis (MP) and to describe its clinical characteristics, therapy and outcome. SUBJECTS AND METHODS: This retrospective study was carried out among patients defined as MP according to computed tomography (CT) scans from January 2012 to December 2015. The CT images were reanalyzed by study radiologists to confirm the previous MP diagnosis. Patients were divided into two groups, idiopathic and secondary, based on the presence or absence of associated predisposing factors such as trauma, malignancy, autoimmune disorders, ischemia or previous abdominal surgery...
October 26, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29066274/self-healing-juvenile-cutaneous-mucinosis-clinical-and-histopathologic-findings-of-nine-cases-the-relevance-of-long-term-follow-up
#18
Isabelle Luchsinger, Jérôme Coulombe, Franco Rongioletti, Marc Haspeslagh, Anne Dompmartin, Isabelle Melki, Rawane Dagher, Brigitte Bader-Meunier, Sylvie Fraitag, Christine Bodemer
BACKGROUND: Self-healing juvenile cutaneous mucinosis (SHJCM) is a rare disorder and the pathogenesis and long-term prognosis are unknown. OBJECTIVES: To elucidate the clinical and histopathologic characteristics, pathogenesis and outcome in patients with SHJCM. METHODS: Retrospective study of 9 patients with SHCJM. To complement initial findings, data collection forms were sent to the referring physicians. RESULTS: All patients had an acute onset of firm nodules...
October 21, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29039997/orbital-t-cell-lymphoma-versus-lupus-panniculitits-a-t-cell-mediated-spectrum-of-orbital-lymphoproliferative-disease
#19
Alison B Huggins, Charles Kim, Michael P Rabinowitz
This is a case description of a single male patient found to have T-cell-mediated inflammation and lymphoproliferation of the orbit. Chronic T-cell-mediated inflammatory disease can pose a diagnostic challenge particularly in its differentiation from a neoplastic process. The histopathology in this case demonstrated features of both lupus erythematosus panniculitis and features of orbital T-cell lymphoma. While both are rare, lupus erythematosus panniculitis of the orbit is even more exceptional; this patient's indolent, chronic relapsing course distinguished itself from the typical aggression of orbital T-cell lymphoma...
October 17, 2017: Orbit
https://www.readbyqxmd.com/read/28984694/cold-induced-dermatoses-case-report-and-review-of-literature
#20
Barbara Saenz Ibarra, Jason Meeker, Omid Jalali, Michael C Lynch
Cold panniculitis and perniosis are the most common cold-induced dermatologic disorders and are clinically characterized by indurated and erythematous nodules and plaques that develop at sites exposed to excessive cold and wet conditions. Cold panniculitis is most commonly seen in infants, but adult cases involving the thighs of equestrians are well known and have come to be known as equestrian cold panniculitis or equestrian perniosis. Recently, similar cases have been described in nonequestrian settings with the prolonged use of ice-packs or other cold-therapy devices...
September 27, 2017: American Journal of Dermatopathology
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