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Uterine contraction

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https://www.readbyqxmd.com/read/28433870/automated-detection-of-premature-delivery-using-empirical-mode-and-wavelet-packet-decomposition-techniques-with-uterine-electromyogram-signals
#1
U Rajendra Acharya, Vidya K Sudarshan, Soon Qing Rong, Zechariah Tan, Choo Min Lim, Joel Ew Koh, Sujatha Nayak, Sulatha V Bhandary
An accurate detection of preterm labor and the risk of preterm delivery before 37 weeks of gestational age is crucial to increase the chance of survival rate for both mother and the infant. Thus, the uterine contractions measured using uterine electromyogram (EMG) or electro hysterogram (EHG) need to have high sensitivity in the detection of true preterm labor signs. However, visual observation and manual interpretation of EHG signals at the time of emergency situation may lead to errors. Therefore, the employment of computer-based approaches can assist in fast and accurate detection during the emergency situation...
April 18, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28426160/assessment-and-support-during-early-labour-for-improving-birth-outcomes
#2
REVIEW
Shinobu Kobayashi, Nobutsugu Hanada, Masayo Matsuzaki, Kenji Takehara, Erika Ota, Hatoko Sasaki, Chie Nagata, Rintaro Mori
BACKGROUND: The progress of labour in the early or latent phase is usually slow and may include painful uterine contractions. Women may feel distressed and lose their confidence during this phase. Support and assessment interventions have been assessed in two previous Cochrane Reviews. This review updates and replaces these two reviews, which have become out of date. OBJECTIVES: To investigate the effectiveness of assessment and support interventions for women during early labour...
April 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28423971/intrauterine-infection-immune-system-and-premature-birth
#3
Fernanda Rodrigues Helmo, Eduardo Arthur Rodovalho Alves, Renata Alves de Andrade Moreira, Viviane Oliveira Severino, Laura Penna Rocha, Maria Luíza Gonçalves Dos Reis Monteiro, Marlene Antônia Dos Reis, Renata Margarida Etchebehere, Juliana Reis Machado, Rosana Rosa Miranda Corrêa
Preterm birth accounts for nearly one million deaths among children under five years of age, and although its etiopathogenesis is not fully elucidated, ascending intrauterine infection and fetal inflammatory response seem to be the main triggers. The intense inflammatory response mediated by IL-1β, TNF-α, PAF, IFN-γ and IL-6, PGE2 and MMP-1 and MMP-9 causes fetal membrane damage and rupture, increased uterine contractions and biochemical and structural changes in the cervix. Furthermore, preterm neonates have deficient innate and adaptive immune responses characterized by reduced levels of IgG, opsonization and phagocytosis, as well as increased activation of Th1 cells in relation to Th2 cells...
April 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28412845/fetal-and-maternal-temperatures-during-labor-and-delivery-a-prospective-descriptive-study
#4
Tony Lavesson, Karin Källén, Per Olofsson
OBJECTIVE: To study the fetal scalp temperature (FST) and maternal axillary temperature (MAT) during vaginal delivery relative to progression of labor, uterine contractions (UC) and epidural analgesia (EDA), and to construct normal temperature reference ranges related to stage of labor. MATERIAL AND METHODS: Temperatures were recorded continuously in labor of 132 women with a bi-metal temperature sensor attached to the axilla (MAT) and a similar sensor mounted in a scalp electrode (FST)...
April 16, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28412086/tocolysis-after-preterm-premature-rupture-of-membranes-and-neonatal-outcome-a-propensity-score-analysis
#5
Elsa Lorthe, François Goffinet, Stéphane Marret, Christophe Vayssiere, Cyril Flamant, Mathilde Quere, Valérie Benhammou, Pierre-Yves Ancel, Gilles Kayem
BACKGROUND: There are conflicting results regarding tocolysis in cases of preterm premature rupture of membranes. Delaying delivery may reduce neonatal morbidity due to prematurity, allow for prenatal corticosteroids and, if necessary, in utero transfer. However, that may increase risks of maternofetal infection and its adverse consequences. OBJECTIVE: To investigate whether tocolytic therapy in cases of preterm premature rupture of membranes is associated with improved neonatal or obstetric outcomes...
April 12, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28409497/identification-of-myoelectric-signals-of-pregnant-rat-uterus-new-method-to-detect-myometrial-contraction
#6
Kálmán F Szűcs, György Grosz, Miklós Süle, Anikó Nagy, Zita Tiszai, Reza Samavati, Róbert Gáspár
AIM: To develop an electromyography method for pregnant rat uterus in vivo and to separate myometrial signals from the gastrointestinal tract signals. METHODS: Pregnant Sprague-Dawley rats (n=8) were anaesthetized and their stomach, small intestine, and large intestine were removed from the abdomen. A pair of thread electrodes was inserted into the uterus, while a pair of disk electrodes was placed subcutaneously above the myometrium. Additionally, a strain gauge sensor was fixed on the surface of the myometrium and cecum for the parallel detection of mechanical contractions in rats (n=18) with intact gastrointestinal tract...
April 14, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/28400465/hypercholesterolemia-impairs-oxytocin-induced-uterine-contractility-in-late-pregnant-mouse
#7
Amol R Padol, Susanth V Sukumaran, Abdul Sadam, Manickam Kesavan, Kandasamy Arunvikram, Ankita D Verma, Vivek Srivastava, Manjit Panigrahi, Thakur Uttam Singh, Avinash G Telang, Santosh K Mishra, Subhashree Parida
High cholesterol is known to negatively affect uterine contractility in ex vivo conditions. The aim of the present study was to reveal the effect of in vivo hypercholesterolemia on spontaneous and oxytocin-induced uterine contractility in late pregnant mouse uterus. Female Swiss albino mice were fed with high cholesterol (HC) diet (0.5% sodium cholate, 1.25% cholesterol and 15% fat) for 6 weeks and then throughout the gestation period after mating. On day 19 of gestation, serum cholesterol level was increased more than 3-fold while triglycerides level was reduced in HC diet-fed animals as compared to control animals fed with a standard diet...
May 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28376638/transabdominal-collection-of-amniotic-fluid-sludge-and-identification-of-candida-albicans-intra-amniotic-infection
#8
Juan P Kusanovic, Roberto Romero, Carolina Martinovic, Karla Silva, Offer Erez, Eli Maymon, Francisco Díaz, Fernando Ferrer, Rafael Valdés, Víctor Córdova, Paula Vargas, María Elena Nilo, Patricio Le Cerf
A G3P2 patient who conceived with an intrauterine contraceptive device (IUD) presented at 20 weeks of gestation with mild irregular uterine contractions and vaginal bleeding. Sonographic examination at admission showed the presence of dense amniotic fluid "sludge" and a long sonographic uterine cervix (42 mms). To assess the microbiologic significance of amniotic fluid "sludge", we performed a transabdominal amniocentesis. The procedure was performed under real-time ultrasound, and fluid resembling pus at gross examination was noted...
April 5, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28372536/hoxa10-and-hoxa11-regulate-the-expression-of-contraction-associated-proteins-and-contribute-to-regionalized-myometrium-phenotypes-in-women
#9
Yinan Li, Haolong Li, Ning Xie, Ruiqi Chen, Ahn Rhi Lee, Donna Slater, Stephen Lye, Xuesen Dong
A relaxed fundus (FUN) and a contracted lower uterine segment (LUS) of human myometrium are required for maintaining pregnancy. How this regional myometrium function is regulated remains unclear. We have previously reported that the homeobox protein A13 (HoxA13) is highly expressed in the LUS and can enhance the expression of contraction-associated proteins (CAPs). Here, we show that in contrast to HoxA13, HoxA10 and HoxA11 genes are expressed at significantly higher levels in myometrium tissues and primary myocytes from the FUN...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28368790/-should-physical-activity-be-contraindicated-during-pregnancy-in-relation-to-its-potentially-related-risks
#10
S Verdière, B C Guinhouya, D Salerno, P Deruelle
OBJECTIVE: This paper aimed at providing a critical analysis of data on the risks associated with physical activity of women during their pregnancy. METHODS: Cochrane Library, Google Scholar, PubMed (Medline) and Web of Sciences were searched using a combination of MeSH terms associated to "Physical activity", "Pregnancy" and "Adverse events" or "Risks". Only review papers published from inception of these databases to November 2016 were used in the present analysis...
February 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/28358713/the-effect-of-extracellular-atp-on-rat-uterine-contraction-from-different-gestational-stages-and-its-possible-mechanisms-of-action
#11
Hind A Zafrah, Mohammed F Alotaibi
BACKGROUND: The mechanisms underlying the onset of labor are not fully understood. Extracellular adenosine 5'-triphosphate (ATP) is known to cause uterine contractions in different species but the exact underlying mechanisms are poorly investigated to date. The aims of this study were to investigate the effect of extracellular ATP on spontaneous uterine contractions from different gestational stages and to elucidate its possible underlying mechanisms. METHODS: Longitudinal uterine strips were obtained from rats in different gestational stages (nonpregnant, late-pregnant, and term-pregnant)...
March 30, 2017: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/28349526/pushing-bearing-down-methods-for-the-second-stage-of-labour
#12
REVIEW
Andrea Lemos, Melania Mr Amorim, Armele Dornelas de Andrade, Ariani I de Souza, José Eulálio Cabral Filho, Jailson B Correia
BACKGROUND: Maternal pushing during the second stage of labour is an important and indispensable contributor to the involuntary expulsive force developed by uterine contraction. There is no consensus on an ideal strategy to facilitate these expulsive efforts and there are contradictory results about the influence on the mother and fetus. OBJECTIVES: To evaluate the benefits and possible disadvantages of different kinds of techniques regarding maternal pushing/breathing during the expulsive stage of labour on maternal and fetal outcomes...
March 26, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28345486/objective-analysis-of-vaginal-ultrasound-video-clips-for-exploring-uterine-peristalsis-post-vaginal-and-cesarean-section-deliveries
#13
Silvia Gora, David Elad, Ariel J Jaffa
The nonpregnant uterus is characterized by cyclic contractions that assist in sperm transport to the fallopian tube, embryo transport to implantation site, and expulsion of menstrual debris. The effect of post-Cesarean section (CS) scar on uterine peristalsis is unclear, while worldwide the prevalence of CS deliveries is increasing. In this study, we developed a new objective method for analysis of dynamic characteristics of the nonpregnant uterus from transvaginal ultrasound (TVUS) recordings when the uterine cavity is not clearly observed, as may be the case in post-CS uteri...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28333087/magnetically-bioprinted-human-myometrial-3d-cell-rings-as-a-model-for-uterine-contractility
#14
Glauco R Souza, Hubert Tseng, Jacob A Gage, Arunmani Mani, Pujan Desai, Fransisca Leonard, Angela Liao, Monica Longo, Jerrie S Refuerzo, Biana Godin
Deregulation in uterine contractility can cause common pathological disorders of the female reproductive system, including preterm labor, infertility, inappropriate implantation, and irregular menstrual cycle. A better understanding of human myometrium contractility is essential to designing and testing interventions for these important clinical problems. Robust studies on the physiology of human uterine contractions require in vitro models, utilizing a human source. Importantly, uterine contractility is a three-dimensionally (3D)-coordinated phenomenon and should be studied in a 3D environment...
March 23, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28328535/the-assessment-of-labor-a-brief-history
#15
Wayne R Cohen, Emanuel A Friedman
In the 1930s, investigators in the US, Germany and Switzerland made the first attempts to quantify the course of labor in a clinically meaningful way. They emphasized the rupture of membranes as a pivotal event governing labor progress. Attention was also placed on the total number of contractions as a guide to normality. Beginning in the 1950s, Friedman determined that changes in cervical dilatation and fetal station over time were the most useful parameters for the assessment of labor progress. He showed all normal labors had similar patterns of dilatation and descent, differing only in the durations and slopes of their component parts...
March 22, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28326570/reproductive-disorders-in-female-rats-after-prenatal-exposure-to-betamethasone
#16
Cibele S Borges, Tainá L Pacheco, Marina T Guerra, Aline L Barros, Patricia V Silva, Gabriela Missassi, Katiussia Pinho da Silva, Janete A Anselmo-Franci, André S Pupo, Wilma De G Kempinas
Betamethasone is the drug of choice for antenatal treatment, promoting fetal lung maturation and decreasing mortality. Previous studies in rats reported male programming and alteration in sperm parameters and sexual behavior following intrauterine betamethasone exposure. The impact on the female reproductive development is not known. In this study, rat female offspring was assessed for sexual development, morphophysiology of the reproductive tract and fertility after maternal exposure to 0.1 mg kg(-1) of betamethasone or vehicle on gestational days 12, 13, 18 and 19...
March 21, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/28326517/labour-in-women-with-gestational-diabetes-mellitus
#17
Klaudia Grabowska, Angelika Stapińska-Syniec, Aleksandra Saletra, Patrycja Jarmużek, Dorota Bomba-Opoń
OBJECTIVES: Gestational diabetes mellitus (GDM) constitutes one of the most common pregnancy complications and affects 3-5% of all pregnancies, with its incidence still growing. Due to possible maternal and fetal complications, the peripartum management of GDM patients continues to be a debatable issue. The aim of the study was to analyse the course and final way of delivery in women with gestational diabetes mellitus. The effectiveness of induction of labour (IOL) was also assessed and factors predisposing to cesarean section were identified...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28316639/feature-extraction-and-classification-of-ehg-between-pregnancy-and-labour-group-using-hilbert-huang-transform-and-extreme-learning-machine
#18
Lili Chen, Yaru Hao
Preterm birth (PTB) is the leading cause of perinatal mortality and long-term morbidity, which results in significant health and economic problems. The early detection of PTB has great significance for its prevention. The electrohysterogram (EHG) related to uterine contraction is a noninvasive, real-time, and automatic novel technology which can be used to detect, diagnose, or predict PTB. This paper presents a method for feature extraction and classification of EHG between pregnancy and labour group, based on Hilbert-Huang transform (HHT) and extreme learning machine (ELM)...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28298752/quality-of-labor-epidural-analgesia-and-maternal-outcome-with-levobupivacaine-and-ropivacaine-a-double-blinded-randomized-trial
#19
T Senthil Kumar, P Rani, V R Hemanth Kumar, Sunita Samal, S Parthasarathy, M Ravishankar
BACKGROUND: Quality of labor analgesia plays a vital role in the maternal outcome. Very few literature are available analyzing the quality of epidural labor analgesia. AIM: The aim of this study was to compare the effectiveness of 0.1% levobupivacaine and 0.1% ropivacaine with fentanyl as an adjuvant for epidural labor analgesia in terms of onset, duration, quality of analgesia, and degree of motor blockade. METHODOLOGY: Sixty nulliparous parturients, with singleton uncomplicated pregnancy, were recruited by continuous sampling...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28295156/identification-of-first-stage-labor-arrest-by-electromyography-in-term-nulliparous-women-after-induction-of-labor
#20
Blanka Vasak, Elisabeth M Graatsma, Elske Hekman-Drost, Marinus J Eijkemans, Jules H Schagen Van Leeuwen, Gerard H A Visser, Benoit C Jacod
Worldwide induction and cesarean delivery rates have increased rapidly, with consequences for subsequent pregnancies. The majority of intra-partum cesarean deliveries are performed for failure to progress, typically in nulliparous women at term. Current uterine registration techniques fail to identify inefficient contractions leading to first stage labor arrest. An alternative technique, uterine electromyography has been shown to identify inefficient contractions leading to first stage arrest of labor in nulliparous women with spontaneous onset of labor at term...
March 12, 2017: Acta Obstetricia et Gynecologica Scandinavica
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