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Diabetic striatopathy

Elisabeth B Lucassen, William T Delfyett, Mark C Stahl
Background: Neurological complications of diabetes and hyperglycemia are relatively common but the specific manifestations can vary widely. Diabetic striatal disease or "diabetic striatopathy" is an uncommon condition usually thought to result from hyperglycemic injury to the basal ganglia, producing a hyperkinetic movement disorder, usually choreiform in nature. Symptoms are generally reversible with treatment of the hyperglycemia. Case Description: We report the case of a 57-year-old woman presenting with a unilateral choreoathetosis of the left upper extremity, persistent for 4 years...
September 2017: Case Reports in Neurology
Hiroki Sato, Makoto Hamano, Etsuko Fushimi, Toshiaki Takahashi, Yohei Horikawa, Satoru Horiguchi
BACKGROUND: Diabetic striatopathy, one of the complications of diabetes mellitus, is characterized by involuntary movements, including hemichorea and hemiballismus, and the presence of hyperintense lesions on T1-weighted magnetic resonance imaging of the striatum. CASE REPORT: We present a case of diabetic striatopathy manifesting as severe consciousness disturbance without chorea or ballismus. A 58-year-old man was admitted to our hospital in a state of unconsciousness...
October 17, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
Liza Das, Rimesh Pal, Pinaki Dutta, Anil Bhansali
"Diabetic striatopathy" is characterized by dyskinesias with basal ganglia hyperintensities on neuroimaging. It is usually reported in elderly females with hyperglycemic hyperosmolar state and rare in patients with diabetic ketoacidosis. Here, we report two young males with diabetic ketoacidosis presenting as striatopathy, along with review of literature.
June 2017: Diabetes Research and Clinical Practice
Chiu-Jung Lin, Poyin Huang
Diabetic striatopathy is an uncommon and life threatening manifestation of diabetes mellitus. It has a tendency to occur in the elderly, female and people of Asian descent. Patients usually present with hemichorea-hemiballism caused by non-ketotic hyperglycemia. However, patients could develop diabetic striatopathy weeks after the hyperglycemic event, even when blood sugar has been well controlled. Herein, we report a case of delayed onset diabetic striatopathy and discuss the importance of detailed history and brain magnetic resonance imaging for making prompt and accurate diagnosis...
July 2017: American Journal of Emergency Medicine
(no author information available yet)
No abstract text is available yet for this article.
July 2016: Pediatrics
Inbal Shafran, Gahl Greenberg, Ehud Grossman, Avshalom Leibowitz
BACKGROUND: Diabetic striatopathy (DS) is a rare complication of diabetes mellitus (DM). The syndrome appears in patients with uncontrolled DM and is characterized by abrupt onset of movement disorder, mainly hemichorea and accompanied by specific findings on brain imaging. It is believed that DS is unique to the Asian population and affects mainly elderly women with uncontrolled DM. METHODS: In order to define existence and characterization of DS in Western population, we reviewed the medical records of all patients admitted to the Chaim Sheba Medical Center between 2004 and 2014 and identified those with documented elevated HbA1c (>10%)...
November 2016: European Journal of Internal Medicine
Ashlesha Satish Udare, Shilpa Sankhe, Prabath Kumar Mondel
No abstract text is available yet for this article.
April 2016: Asian Journal of Neurosurgery
Tamara Faundez, Philippe Klee, Sylviane Hanquinet, Valérie Schwitzgebel, Pierre R Burkhard, Christian M Korff
Diabetic striatopathy is a well-known complication of diabetes in adults. To our knowledge, only 2 cases have been reported in children. We here report the case of a teenager in whom diabetic striatopathy was revealed by the subacute appearance of hemichorea-hemiballism in the context of weight loss, polyuria, and polydipsia. Glycemia control allowed rapid clinical recovery despite established striatal lesions documented on MRI. We also discuss current hypotheses about pathophysiological processes underlying this entity...
April 2016: Pediatrics
Anıl Özgür, Kaan Esen, Hakan Kaleağası, Arda Yılmaz, Engin Kara
Diabetic striatopathy is a rare and life-threatening manifestation of diabetes mellitus. The disease commonly affects individuals of Asian descent, females, and the elderly. Patients usually present with hemiballism-hemichorea caused by nonketotic hyperglycemia. Hemiballism-hemichorea is defined as involuntary continuous random appearing movement involving one side of the body. This movement disorder may develop secondary to stroke, diabetic striatopathy, neoplasm, infection, Wilson's disease, and thyrotoxicosis...
June 2015: Emergency Radiology
Abhijai Singh
No abstract text is available yet for this article.
August 2013: Mayo Clinic Proceedings
Yoshinori Abe, Teiji Yamamoto, Tomoko Soeda, Tomohiro Kumagai, Yoshihiro Tanno, Jin Kubo, Tetsuya Ishihara, Soichi Katayama
BACKGROUND: Unilateral movement disorders and contralateral neuroimaging abnormalities of the striatum have been sporadically reported as a rare syndrome associated with diabetes mellitus. Despite characteristic imaging findings and clinical manifestations, the mechanism underlying this syndrome is still unclear. METHODS: Six patients with this syndrome were studied clinically and subjected to MRI neuroimaging; one underwent biopsy of the striatum, and another underwent additional MR spectroscopy at 3...
2009: Internal Medicine
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