keyword
MENU ▼
Read by QxMD icon Read
search

Neonatal HIV

keyword
https://www.readbyqxmd.com/read/29146286/-genital-herpes-and-pregnancy-epidemiology-clinical-manifestations-prevention-and-screening-guidelines-for-clinical-practice-from-the-french-college-of-gynecologists-and-obstetrician-cngof
#1
O Picone
OBJECTIVES: To analyze the consequences of genital herpes infections in pregnant women. METHODS: The PubMed database and the recommendations from the French and foreign obstetrical societies or colleges have been consulted. RESULTS: The symptomatology of herpes genital rash is often atypical (NP2) and not different during pregnancy (Professional consensus). It is most often due to HSV2 (NP2). Seventy percent of pregnant patients have a history of infection with Herpes simplex virus, without reference to genital or labial localization, and this is in most cases type 1 (NP2)...
November 13, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29132770/-management-of-pregnant-women-with-recurrent-herpes-guidelines-for-clinical-practice-from-the-french-college-of-gynecologists-obstetricians-cngof
#2
O Anselem
OBJECTIVE: To provide guidelines for the management of woman with genital herpes during pregnancy or labor and with known history of genital herpes. METHODS: MedLine and Cochrane Library databases search and review of the main foreign guidelines. RESULTS: Genital herpes ulceration during pregnancy in a woman with history of genital herpes correspond to a recurrence. In this situation, there is no need for virologic confirmation (Grade B). In case of recurrent herpes during pregnancy, antiviral therapy with acyclovir or valacyclovir can be administered but provide low efficiency on duration and severity of symptoms (Grade C)...
November 10, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29116590/detection-of-congenital-cytomegalovirus-in-newborns-using-nucleic-acid-amplification-techniques-and-its-public-health-implications
#3
REVIEW
Guoyu Liu, Rong Hai, Fenyong Liu
Human cytomegalovirus (HCMV), a herpesvirus, is an important human pathogen that causes asymptomatic infections in healthy or immunocompetent individuals but can lead to severe and potentially life-threatening complications in immune-immature individuals such as neonates or immune-compromised patients such as organ-transplant recipients and HIV-positive individuals. Congenital HCMV infection represents a significant public health issue and poses substantial healthcare and economic burden to society. This virus causes the most common viral congenital infection worldwide, and is the leading non-genetic cause of sensorineural hearing loss in children in developed countries...
October 2017: Virologica Sinica
https://www.readbyqxmd.com/read/29104766/variation-in-neonatal-mortality-and-its-relation-to-country-characteristics-in-sub-saharan-africa-an-ecological-study
#4
Gbenga Ayodele Kayode, Diederick E Grobbee, Mary Amoakoh-Coleman, Evelyn Ansah, Olalekan A Uthman, Kerstin Klipstein-Grobusch
Background: A substantial reduction in neonatal mortality is the main priority to reduce under-five mortality. A clear understanding of the variation in neonatal mortality and the underlying causes is important for targeted intervention. We aimed to explore variation in neonatal mortality and identify underlying causes of variation in neonatal mortality in sub-Saharan Africa (SSA). Methods: This ecological study used 2012 publicly available data from WHO, the US Agency for International Development and the World Bank...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/29098898/the-pharmacological-treatment-of-acute-hiv-infections-in-neonates
#5
Louise Kuhn, Stephanie Shiau
Recent goals of antiretroviral treatment of neonates have expanded from reducing morbidity and mortality to also aiming to facilitate HIV remission. Areas covered: In this review, we present and discuss the rationale and evidence-bases for each of these distinct goals. Next we discuss the challenges of how to identify HIV-infected neonates. Finally, we discuss the specific antiretroviral drugs that are preferred for this group, making distinctions between the use of these agents in prevention and treatment...
November 3, 2017: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/29074060/risk-factors-for-cerebral-palsy-in-children-in-botswana
#6
Baphaleng Monokwane, Allison Johnson, Claudia Gambrah-Sampaney, Esha Khurana, James Baier, Esther Baranov, Kate D Westmoreland, Loeto Mazhani, Andrew P Steenhoff, David R Bearden
BACKGROUND: Although cerebral palsy is reported to have a higher prevalence in low-resource settings, there are few studies describing risk factors for cerebral palsy in these settings. A better understanding of the unique risk factors affecting children with cerebral palsy in low-resource settings could optimize both resource allocation and preventative strategies. METHODS: A case-control study comparing children with cerebral palsy at ages two to 18 years with age-matched healthy control subjects was conducted between 2013 and 2014 at a referral center in Gaborone, Botswana...
August 3, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29062060/role-of-hiv-exposure-and-infection-in-relation-to-neonatal-gbs-disease-and-rectovaginal-gbs-carriage-a-systematic-review-and-meta-analysis
#7
Piet Cools, Janneke H H M van de Wijgert, Vicky Jespers, Tania Crucitti, Eduard J Sanders, Hans Verstraelen, Mario Vaneechoutte
Streptococcus agalactiae (GBS) is the leading cause worldwide of neonatal sepsis. We sought to assess to which extent HIV exposure of neonates is associated with GBS neonatal disease. Furthermore, we assessed to which extent HIV infection in women is associated with maternal rectovaginal GBS carriage, the single most important risk factor for GBS neonatal disease. We searched Pubmed, Embase, and Web of Science for studies assessing the association between neonatal GBS disease and HIV-status of the mother and studies that assessed the association between rectovaginal GBS colonization and HIV status in women...
October 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29053932/the-patterns-of-in-vitro-cell-death-and-inflammatory-cytokines-induced-by-distinct-bcg-vaccine-strains-are-differentially-induced-in-human-mononuclear-cells
#8
C Ponte, M Hacker, M Moraes, L Castello-Branco, F Silva, P Antas
Tuberculosis (TB) remains among the world's leading cause of mortality. For its control, studies of TB vaccines are needed. Since live-attenuated Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the only TB vaccine currently in use, studies on the protective role of BCG are required. In this study, we analyzed host cells purified directly from whole blood of human immunodeficiency virus (HIV)-negative volunteers, comprising adult healthy donors (HD) and neonates (umbilical cord bloods, UCB), with the aim to directly compare in vitro immune responses with distinct BCG strains in human mononuclear cells...
October 20, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29040666/maternal-tenofovir-disoproxil-fumarate-use-during-pregnancy-is-not-associated-with-adverse-perinatal-outcomes-among-hiv-infected-east-african-women-a-prospective-study
#9
Jillian Pintye, Jared M Baeten, Connie Celum, Nelly Mugo, Kenneth Ngure, Edwin Were, Elizabeth Bukusi, Grace John-Stewart, Renee A Heffron
Background: Tenofovir disoproxil fumarate (TDF) is commonly used in antiretroviral treatment (ART) and pre-exposure prophylaxis regimens. We evaluated the relationship between adverse perinatal outcomes and prenatal TDF use. Methods: Longitudinal data were analyzed from HIV-infected women who became pregnant during two HIV prevention studies conducted among HIV-serodiscordant couples in Kenya and Uganda. Pregnancies were included if singleton, not terminated by an induced abortion and had documentation of 3-drug ART use...
October 10, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29039686/prevention-and-treatment-of-hiv-infection-in-neonates-evidence-base-for-existing-who-dosing-recommendations-and-implementation-considerations
#10
Diana F Clarke, Martina Penazzato, Edmund Capparelli, Tim R Cressey, George Siberry, Nandita Sugandhi, Mark Mirochnick
Antiretroviral drugs are used in neonates for prevention and treatment of HIV infection. Use of antiretrovirals to prevent perinatal HIV transmission is well established. Early identification of neonates infected with HIV and rapid initiation of combination antiretroviral treatment during the neonatal period is now recommended by WHO and DHHS. However, few antiretrovirals are available in formulations suitable for neonates and there are limited safety and pharmacokinetic data for most antiretrovirals in neonates...
October 17, 2017: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/29035947/cross-reactivity-of-hiv-vaccine-responses-and-the-microbiome
#11
Wilton B Williams, Qifeng Han, Barton F Haynes
PURPOSE OF REVIEW: A successful HIV-type 1 (HIV-1) vaccine will require immunogens that induce protective immune responses. However, recent studies suggest that the response to HIV-1 and perhaps other viruses may be altered by immune system exposure to intestinal microbiota-antigens. This review will discuss select aspects of these studies. RECENT FINDINGS: Naïve CD4 T and B cell repertoires can be imprinted by intestinal microbiota-antigens to respond to virus epitopes prior to virus infection...
October 14, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/29029337/protective-effect-of-indoor-residual-spraying-of-insecticide-on-preterm-birth-among-pregnant-women-with-hiv-in-uganda-a-secondary-data-analysis
#12
Michelle E Roh, Stephen Shiboski, Paul Natureeba, Abel Kakuru, Mary Muhindo, Teddy Ochieng, Albert Plenty, Catherine A Koss, Tamara D Clark, Patricia Awori, Miriam Nakalambe, Deborah Cohan, Prasanna Jagannathan, Roly Gosling, Diane V Havlir, Moses R Kamya, Grant Dorsey
Background: Recent evidence demonstrated improved birth outcomes among HIV-uninfected pregnant women protected by indoor residual spraying of insecticide (IRS). Evidence regarding its impact on HIV-infected pregnant women is lacking. Methods: Data were pooled from two studies conducted before-and-after an IRS campaign in Tororo, Uganda among HIV-infected pregnant women who received bednets, daily trimethoprim-sulfamethoxazole (TMP-SMX), and combination antiretroviral therapy (c-ART) at enrollment...
October 6, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29028970/poor-obstetric-and-infant-outcomes-in-hiv-infected-pregnant-women-with-tuberculosis-in-south-africa-the-tshepiso-study
#13
Nicole Salazar-Austin, Jennifer Hoffmann, Silvia Cohn, Fildah Mashabela, Ziyaad Waja, Sanjay Lala, Christopher Hoffmann, Kelly E Dooley, Richard E Chaisson, Neil Martinson
Background: Prior to the wide availability of antiretroviral therapy, tuberculosis (TB) and HIV disease among pregnant women resulted in poor maternal and neonatal outcomes including high rates of mother-to-child transmission of both HIV and TB. We aimed to describe the impact of TB among HIV-infected mothers on obstetric and infant outcomes in a population with access to antiretroviral therapy. Methods: In this prospective cohort study, we followed HIV-infected pregnant women with and without TB disease from January 2011 through January 2014 in Soweto, South Africa...
September 26, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29022569/syphilis
#14
REVIEW
Rosanna W Peeling, David Mabey, Mary L Kamb, Xiang-Sheng Chen, Justin D Radolf, Adele S Benzaken
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. T. pallidum is renowned for its invasiveness and immune-evasiveness; its clinical manifestations result from local inflammatory responses to replicating spirochaetes and often imitate those of other diseases. The spirochaete has a long latent period during which individuals have no signs or symptoms but can remain infectious. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries...
October 12, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29020335/hiv-drug-resistance-in-african-infants-and-young-children-newly-diagnosed-with-hiv-a-multicounty-analysis
#15
Michael R Jordan, Martina Penazzato, Amandine Cournil, Adolfo Vubil, Ilesh Jani, Gillian Hunt, Sergio Carmona, Gugu Maphalala, Nobuhle Mthethwa, Christine Watera, Pontiano Kaleebu, Christine Chakanyuka Musanhu, Sekesai Mtapuri-Zinyowera, Janet Dzangare, Martine Peeters, Chunfu Yang, Neil Parkin, Silvia Bertagnolio
Background: Prevention of mother-to-child transmission (PMTCT) of HIV programs have been scaled-up in many low- and middle-income countries; however, HIV drug resistance (HIVDR) data amongst HIV-1-infected young children remain limited. Methods: Surveys of pre-treatment HIVDR amongst children younger than 18 months of age who were diagnosed with HIV through Early Infant Diagnosis were conducted in five sub-Saharan African countries (Mozambique, Swaziland, South Africa, Uganda, and Zimbabwe) between 2011 and 2014 following World Health Organization guidance...
August 8, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28986656/sustainability-of-statewide-rapid-hiv-testing-in-labor-and-delivery
#16
Lynn M Yee, Emily S Miller, Anne Statton, Laurie D Ayala, Sarah Deardorff Carter, Ann Borders, Amy E Wong, Yolanda Olszewski, Mardge H Cohen, Patricia M Garcia
The objective was to assess sustainability of a statewide program of HIV rapid testing (RT) for pregnant women presenting for delivery with unknown HIV status. This is a population-based retrospective cohort study of women delivered in Illinois hospitals (2012-15). Deidentified data on RT metrics from state-mandated surveillance reports were compared using descriptive statistics and non-parametric tests of trend. Over 95% of the 608,408 women delivered had documented HIV status at presentation. The rate of undocumented HIV status rose from 4...
October 6, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28985403/anthropometric-parameters-of-hiv-infected-and-hiv-uninfected-mothers-and-their-premature-infants
#17
Carike Fouché, Evette van Niekerk, Lisanne Monica du Plessis
This study aimed to assess the maternal anthropometric parameters of human immunodeficiency virus (HIV)-infected and HIV-uninfected mothers as well as to assess the neonatal anthropometric parameters of premature infants in relation to maternal anthropometric parameters (weight, height and mid-upper-arm circumference), HIV status and anti-retroviral therapy (ART) regimen. Study participants included HIV-infected and HIV-uninfected mothers who gave birth to premature infants. All HIV-infected mothers received ART...
August 3, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28982092/health-outcomes-associated-with-crack-cocaine-use-systematic-review-and-meta-analyses
#18
REVIEW
Ainslie J Butler, Jürgen Rehm, Benedikt Fischer
BACKGROUND: Crack-cocaine use is prevalent largely in socio-economically marginalized populations in the Americas. Its use has been associated with diverse health outcomes, yet no recent or systematic reviews of these exist. METHODS: A systematic review of health outcomes associated with crack-cocaine use was performed, using MEDLINE, Scopus, Web of Science, CINAHL, PsycINFO, and LILACS up to October 2016. Search terms included crack-cocaine and health outcome-related keywords, targeting peer-reviewed studies on quantified health outcomes associated with crack-cocaine use...
September 22, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28969210/prevention-of-parent-to-child-transmission-of-hiv-single-centre-experience-of-14-years-at-tertiary-care-hospital-in-delhi-india
#19
A G Radhika, Sonia Chawla, Sruthi Bhaskaran
INTRODUCTION: Prevention of Parent To Child Transmission (PPTCT) of HIV/AIDS is an integral component of AIDS control programme. PPTCT is an ongoing programme since last 15 years. AIM: The aim of the study was to evaluate the reduction in the burden of disease in newborn and infants by prevention of parents to child transmission of HIV/AIDS. MATERIALS AND METHODS: This retrospective study was conducted at Department of Obstetrics and Gynecology in a tertiary care hospital of Delhi from May 2002 to May 2015...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28963998/preventive-newborn-male-circumcision-what-is-the-child-s-best-interest
#20
Maria Luisa Di Pietro, Adele A Teleman, Maria Luisa Di Pietro, Andrea Poscia, Fermín J González-Melado, Nicola Panocchia
Preventive newborn male circumcision has been at the center of scientific debate for many years. The reason for promoting preventive newborn male circumcision, is the reduction of the incidence of UTIs (in the first six months of life), penile cancer, transmission of STDs/HIV infection/AIDS. However preventive interventions in the newborn involving violations of bodily integrity elicit several ethical questions. In this article, we reviewed the literature regarding circumcision, the prevention of UTIs, penile cancer, transmission of STDs/HIV infection/AIDS and complications of this practice in the neonatal period...
September 2017: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
keyword
keyword
96583
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"