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Neurogenic bladder

V B Berdichevskii, B A Berdichevskii
The search for and use of alternative biomarkers of the hyperactive bladder has garnered increasing attention in recent years because they may be considered pathogenetically significant and used as surrogate biomarkers. Promising agents that have met these criteria include proteins cytokines, neurotrophins, tumor necrosis factor (TNF), nerve growth factor (NGF), fibrinopeptides A and B, C-reactive protein, membrane-bound ATPase. Analysis of current scientific literature has demonstrated that specialists in many fields of medicine show interest in endogenous proteins that do not belong to neurotransmitters but affect the contractile ability of myocytes...
May 2018: Urologii︠a︡
Vladimir Mouraviev, Michael McDonald
INTRODUCTION: The changing face of current infection phenotypes from planktonic to biofilm type has been developed implicating bacterial biofilms in recurrent infection. To date, no specific medical treatment exists to specifically target biofilms in the human host. Similarly, the identification of a biofilm has relied upon the analysis of tissue samples with electron microscopy or DNA identification with polymerase chain reaction (PCR) and sequencing. Standard culture and sensitivity test is not able to detect a presence of biofilms...
June 2018: Canadian Journal of Urology
George J Francis, An Ngo-Huang, Laurence D Rhines, Eduardo Bruera
BACKGROUND: Sacral neoplasms often present as large masses that often require sacrectomy. Multiple sacral nerve roots may be compromised post-sacrectomy and postoperative complications may result in impaired mobility, pain, orthostasis, and neurogenic bowel and bladder. CASE REPORTS: CASE #1: 58 year-old female with a sacral solitary fibrous tumor underwent a high-level sacrectomy and bilateral gluteal muscle flaps. Her rehabilitation course included management of pain, orthostasis, and neurogenic bowel and bladder...
June 11, 2018: European Journal of Physical and Rehabilitation Medicine
Amr Hodhod, John-Paul Capolicchio, Roman Jednak, Eid El-Sherif, Abd El-Alim El-Doray, Mohamed El-Sherbiny
Objective: To evaluate the utility of hydroureter (HU) to identify high-grade vesico-ureteric reflux (VUR) in patients with high-grade postnatal hydronephrosis (PH). Patients and methods: We retrospectively reviewed patients' charts that had antenatal hydronephrosis from 2008 to 2014. Patients were excluded if they presented with febrile urinary tract infection (fUTI), neurogenic bladder, posterior urethral valve, multi-cystic dysplastic kidney, and multiple congenital malformations...
June 2018: Arab Journal of Urology
Kerime Ararat, Idanis Berrios, Anas Hannoun, Carolina Ionete
There are only six cases in literature that describe development of dystonia with Sjogren's syndrome (SS). We describe a case of a 43-year-old woman who presented with symptoms including movement disorder, sensory neurogenic bladder, sensory loss and neuropathic pain, migraine like headaches, musculoskeletal pain, Raynaud's phenomenon and dysautonomia. Symptoms started in 2000, with weakness that progressed to dystonia in 2003. Diagnostic work-up was inconclusive with negative inflammatory serologies, cerebrospinal fluid and MRI for many years...
June 4, 2018: BMJ Case Reports
Shivraj Riar, Mohammed Abdulhadi, Christine Day, Bhanu Prasad
Percutaneous insertion of a peritoneal dialysis (PD) catheter has inherent risks of complications, more so if done "blind" (without fluoroscopy and ultrasound guidance). Despite the perceived disadvantages, there are very few reported cases of mechanical complications after PD catheter insertion. We present an 81-year-old man who underwent percutaneous insertion of dual-cuffed coiled Tenckhoff PD catheter under local anesthesia by a trained nephrologist. The procedure was uneventful, and the patient was discharged 45 min later in a stable state...
January 2018: Case Reports in Nephrology and Dialysis
Eric Chung
No abstract text is available yet for this article.
June 4, 2018: Medical Journal of Australia
Sean A Martin, Nicholas R Brook, Gary A Wittert
No abstract text is available yet for this article.
June 4, 2018: Medical Journal of Australia
Evgeniy Kreydin, Blayne Welk, Doreen Chung, Quentin Clemens, Claire Yang, Teresa Danforth, Angelo Gousse, Stephanie Kielb, Stephen Kraus, Altaf Mangera, Sheilagh Reid, Nicole Szell, Francisco Cruz, Emmanuel Chartier-Kastler, David A Ginsberg
PURPOSE: Neurogenic bladder due to spinal cord injury has significant consequences for patients' health and quality of life. Regular surveillance is required to assess the status of the upper and lower urinary lower urinary tracts and prevent their deterioration. In this review, we examine surveillance techniques in neurogenic bladder, describe common complications of this disease, and address strategies for their management. METHODS: This work represents the efforts of SIU-ICUD joint consultation on Urologic Management of the Spinal Cord injury...
May 29, 2018: World Journal of Urology
Ralf Böthig, Kai Fiebag, Birgitt Kowald, Sven Hirschfeld, Roland Thietje, Ines Kurze, Wolfgang Schöps, Holger Böhme, Albert Kaufmann, Michael Zellner, Thura Kadhum, Klaus Golka
INTRODUCTION AND OBJECTIVES:  Life expectancy for people with spinal cord injury/disease (SCI/D) is increasing, due to modern advances in treatment methods and in neuro-urology. However, with the increased life expectancy the risk of developing urinary bladder cancer is gaining importance. How is this patient group different from the general population? METHODS:  Single-centre retrospective evaluation of consecutive patient data with spinal cord injury and proven urinary bladder cancer...
May 29, 2018: Aktuelle Urologie
Bernie Carter, Karen Whittaker, Caroline Sanders
Telehealth as a community-monitoring project within children's urology care is an innovative development. There is limited evidence of the inclusion of staff and parents in the early-stage development and later adoption of telehealth initiatives within routine urological nursing care or families' management of their child's bladder. The aim was to explore the experiences of key stakeholders (parents, clinicians, and technical experts) of the proof of concept telehealth intervention in terms of remote community-based urinalysis monitoring by parents of their child's urine...
January 1, 2018: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
Roderick Clark, Blayne Welk
AIMS: To determine if previous urinary cultures can predict the organism and susceptibility of subsequent urinary cultures in patients with neurogenic bladder dysfunction. METHODS: We retrospectively identified a sample of neurogenic bladder patients from a tertiary care urology clinic (July 2015-July 2016). We reviewed the patient chart, and then used the electronic laboratory record to identify all urine cultures done in the 2 years prior. We identified sequential culture pairs and determined the concordance of the initial culture organism to the subsequent one and similarly the concordance of the initial culture's antibiotic resistance status to the subsequent culture's one...
May 25, 2018: Neurourology and Urodynamics
Daniel Eberli, Maya Horst, Ashkan Mortezavi, Karl-Erik Andersson, Rita Gobet, Tullio Sulser, Hans-Uwe Simon, Souzan Salemi
AIMS: To explore whether autophagy plays a role in the remodeling of bladder smooth muscle cells (SMCs) in children with neurogenic lower urinary tract dysfunction (NLUTD), we investigated the effect of autophagy in NLUTD in the paediatric population. METHODS: Bladder biopsies were taken from children with NLUTD and healthy donors as controls. Samples were labeled with the SMC markers calponin, smoothelin, and the autophagy proteins LC3, ATG5, and Beclin1. The contractile ability of bladder derived SMCs was investigated...
May 24, 2018: Neurourology and Urodynamics
Yuan-Hong Jiang, Sheng-Fu Chen, Jia-Fong Jhang, Hann-Chorng Kuo
PURPOSE: Urethral sphincter hyperactivity resulting in voiding dysfunction is frequently encountered. Medical treatment might not achieve a satisfactory result. OnabotlinumtoxinA urethral sphincter injection relaxes sphincter tonicity and possibly resumes efficient voiding. This study analyzed the treatment outcomes and predictor for successful onabotulinumtoxinA treatment on these patients. METHODS: Patients with voiding dysfunction due to urethral sphincter hyperactivity and treated with injections of 100 U onabotulinumtoxinA into the urethral sphincter were retrospectively reviewed...
May 24, 2018: Neurourology and Urodynamics
Michael A Maccini, David J Chalmers, Vijaya M Vemulakonda, Jeffrey B Campbell
PURPOSE: Urinary tract infections are relatively common in pediatric patients. Unrecognized bacteriuria at the time of urologic surgery puts patients at increased risk for perioperative complications. Many pediatric urologists obtain preoperative or intraoperative urine cultures prior to surgery, but data are lacking regarding rates and risk factors for positive intraoperative urine cultures. We conducted a retrospective cohort study of patients undergoing pediatric urologic surgery to examine factors associated with positive intraoperative urine cultures...
May 21, 2018: International Urology and Nephrology
Jesús Vaquero, Mercedes Zurita, Miguel A Rico, Concepcion Aguayo, Cecilia Fernandez, Gregorio Rodriguez-Boto, Esperanza Marin, Noemi Tapiador, Marta Sevilla, Joaquin Carballido, David Vazquez, Damian Garcia-Olmo, Hector Guadalajara, Miguel Leon, Ignacio Valverde
BACKGROUND AIMS: Recently, clinical studies show that cell therapy with mesenchymal stromal cells (MSCs) improves the sequelae chronically established in paraplegic patients, being necessary to know which of them can obtain better benefit. METHODS: We present here a phase 2 clinical trial that includes six paraplegic patients with post-traumatic syringomyelia who received 300 million MSCs inside the syrinx and who were followed up for 6 months. Clinical scales, urodynamic, neurophysiological, magnetic resonance (MR) and studies of ano-rectal manometry were performed to assess possible improvements...
May 18, 2018: Cytotherapy
Nimrod S Barashi, Maria Veronica Rodriguez, Vignesh T Packiam, Mohan S Gundeti
Neurogenic bladder occur as a consequence of several conditions, most commonly posterior urethral valves syndrome, spina bifida, tethered cord, sacral agenesis, and Arnold-Chiari malformation. It is characterized by diminished bladder capacity and/or reduced compliance, associated with high-pressure voiding that can lead to deterioration of renal function if left untreated. When medical management fails, bladder reconstruction with bowel (aumentation ileocystoplasty) becomes the treatment of choice for these patients...
May 2018: Journal of Endourology
Qianqian Fan, Omer Cavus, Lize Xiong, Yun Xia
Spinal cord injury (SCI) is one of the most common causes of death and disability worldwide, and it can result in both permanent disability and serial complications in patients. Research shows that patients with SCI complications are often interested in acupuncture for symptomatic relief. Therefore, the issue of physicians advising their patients regarding the use of acupuncture to alleviate SCI complications becomes pertinent. We review and summarize two types of relevant publications: (1) literature concerning acupuncture for SCI and its complications and (2) underlying mechanisms of acupuncture therapy for SCI...
May 10, 2018: Journal of Acupuncture and Meridian Studies
Matteo Balzarro, Emanuele Rubilotta, Andrea Braga, Silvia Bassi, Tania Processali, Walter Artibani, Maurizio Serati
OBJECTIVES: The correlation between changes in sexual function and improvements in LUTD in patients treated with OnabotulinumtoxinA (onaBoNT-A) detrusor injection is unclear and limited only to women with neurogenic OAB. The aim of this study was to evaluate the impact of OnabotulinumtoxinA (onaBoNT-A) injection on sexual function in women undergoing this treatment for idiopathic wet overactive bladder (OAB). STUDY DESIGN: This is a pilot three-center observational study including women affected by idiopathic wet overactive bladder refractory to standard conservative treatments and underwent onaBoNT-A injection...
May 5, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Rizwan Hamid, Marcio Augusto Averbeck, Humberto Chiang, Arturo Garcia, Riyad T Al Mousa, Seung-June Oh, Anita Patel, Mauricio Plata, Giulio Del Popolo
Spinal cord injury (SCI) usually affects younger age groups with male preponderance. The most common traumatic cause is road traffic accident followed by sports accidents and gun-shot injuries. Infections and vascular events make up non-traumatic causes. There is regional variance in incidence and prevalence of SCI. Most systematic reviews have been undertaken from USA, Canada, and Australia with only few from Asia with resultant difficulty in estimation of worldwide figures. Overall, the incidence varies from 12 to more than 65 cases/million per year...
May 11, 2018: World Journal of Urology
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