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https://www.readbyqxmd.com/read/28821005/anticonvulsant-effect-of-cannabidiol-in-the-pentylenetetrazole-model-pharmacological-mechanisms-electroencephalographic-profile-and-brain-cytokine-levels
#1
Luciano R Vilela, Isabel V Lima, Érica B Kunsch, Hyorrana Priscila P Pinto, Aline S de Miranda, Érica Leandro M Vieira, Antônio Carlos P de Oliveira, Marcio Flávio D Moraes, Antônio L Teixeira, Fabricio A Moreira
Cannabidiol (CBD), the main nonpsychotomimetic compound from Cannabis sativa, inhibits experimental seizures in animal models and alleviates certain types of intractable epilepsies in patients. Its pharmacological profile, however, is still uncertain. Here we tested the hypothesis that CBD anticonvulsant mechanisms are prevented by cannabinoid (CB1 and CB2) and vanilloid (TRPV1) receptor blockers. We also investigated its effects on electroencephalographic (EEG) activity and hippocampal cytokines in the pentylenetetrazole (PTZ) model...
August 15, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28814801/strain-dependence-of-the-angelman-syndrome-phenotypes-in-ube3a-maternal-deficiency-mice
#2
Heather A Born, An T Dao, Amber T Levine, Wai Ling Lee, Natasha M Mehta, Shubhangi Mehra, Edwin J Weeber, Anne E Anderson
Angelman syndrome (AS) is a genetic neurodevelopmental disorder, most commonly caused by deletion or mutation of the maternal allele of the UBE3A gene, with behavioral phenotypes and seizures as key features. Currently no treatment is available, and therapeutics are often ineffective in controlling AS-associated seizures. Previous publications using the Ube3a maternal deletion model have shown behavioral and seizure susceptibility phenotypes, however findings have been variable and merit characterization of electroencephalographic (EEG) activity...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28813935/influence-of-artifacts-on-movement-intention-decoding-from-eeg-activity-in-severely-paralyzed-stroke-patients
#3
Eduardo Lopez-Larraz, Carlos Bibian, Niels Birbaumer, Ander Ramos-Murguialday
Brain-machine interfaces (BMI) can be used to control robotic and prosthetic devices for rehabilitation of motor disorders, such as stroke. The calibration of these BMI systems is of paramount importance in order to establish a precise contingent link between the brain activity related to movement intention and the peripheral feedback. However, electroencephalographic (EEG) activity, commonly used to build non-invasive BMIs, can be easily contaminated by artifacts of electrical or physiological origin. The way these interferences can affect the performance of movement intention decoders has not been deeply studied, especially when dealing with severely paralyzed patients, which often generate more artifacts by compensatory movements...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813929/soft-brain-machine-interfaces-for-assistive-robotics-a-novel-control-approach
#4
Lucia Schiatti, Jacopo Tessadori, Giacinto Barresi, Leonardo S Mattos, Arash Ajoudani
Robotic systems offer the possibility of improving the life quality of people with severe motor disabilities, enhancing the individual's degree of independence and interaction with the external environment. In this direction, the operator's residual functions must be exploited for the control of the robot movements and the underlying dynamic interaction through intuitive and effective human-robot interfaces. Towards this end, this work aims at exploring the potential of a novel Soft Brain-Machine Interface (BMI), suitable for dynamic execution of remote manipulation tasks for a wide range of patients...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813921/effect-on-the-classification-of-motor-imagery-in-eeg-after-applying-anodal-tdcs-with-a-4%C3%A3-1-ring-montage-over-the-motor-cortex
#5
I N Angulo-Sherman, M Rodriguez-Ugarte, E Ianez, M Ortiz, J M Azorin
Transcranial direct stimulation (tDCS) is a technique for modulating brain excitability that has potential to be used in motor neurorehabilitation by enhancing motor activity, such as motor imagery (MI). tDCS effects depend on different factors, like current density and the position of the stimulating electrodes. This study presents preliminary results of the evaluation of the effect of current density on MI performance by measuring right-hand/feet MI accuracy of classification from electroencephalographic (EEG) measurements after anodal tDCS is applied with a 4×1 ring montage over the right-hand or feet motor cortex...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28811719/refractory-hepatic-encephalopathy-in-a-patient-with-hypothyroidism-another-element-in-ammonia-metabolism
#6
Fernando Díaz-Fontenla, Marta Castillo-Pradillo, Arantxa Díaz-Gómez, Luis Ibañez-Samaniego, Pilar Gancedo, Juan Adan Guzmán-de-Villoria, Pilar Fernández-García, Rafael Bañares-Cañizares, Rita García-Martínez
Hepatic encephalopathy (HE) remains a diagnosis of exclusion due to the lack of specific signs and symptoms. Refractory HE is an uncommon but serious condition that requires the search of hidden precipitating events (i.e., portosystemic shunt) and alternative diagnosis. Hypothyroidism shares clinical manifestations with HE and is usually considered within the differential diagnosis of HE. Here, we describe a patient with refractory HE who presented a large portosystemic shunt and post-ablative hypothyroidism...
July 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28809705/effects-of-continuous-kinaesthetic-feedback-based-on-tendon-vibration-on-motor-imagery-bci-performance
#7
M Barsotti, D Leonardis, N Vanello, M Bergamasco, A Frisoli
BACKGROUND AND OBJECTIVES: Feedback plays a crucial role for using Brain Computer Interface (BCI) systems. This study proposes the use of vibration-evoked kinaesthetic illusions as part of a novel multisensory feedback for a Motor Imagery (MI) based BCI and investigates its contributions in terms of BCI performance and electroencephalographic (EEG) correlates. METHODS: Sixteen subjects performed two different right arm MI-BCI sessions: with the visual feedback only and with both visual and vibration-evoked kinaesthetic feedback, conveyed by the stimulation of the biceps brachi tendon...
August 14, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28804979/kleine-levin-syndrome-elicited-by-encephalopathy-with-reversible-splenial-lesion
#8
Masaru Takayanagi, Shinichi Okabe, Katsuya Yamamoto, Juri Komatsu, Rikio Suzuki, Taro Kitamura, Toshihiro Ohura
Kleine-Levin syndrome is a rare sleep disorder of unknown etiology characterized by repetitive episodes of hypersomnia between asymptomatic periods. We report the case of a 13-year-old girl who presented with drowsiness triggered by influenza A as the first episode. Magnetic resonance imaging (MRI) on day 6 showed transient reduction of diffusion in the corpus callosum splenium. The patient was diagnosed with encephalopathy with a reversible splenial lesion. The symptoms resolved after 10 days, but additional episodes of hypersomnia lasting 5-10 days occurred 1, 5, 6, 11, 13, and 25 months after the first episode...
August 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28803030/neurofeedback-sham-neurofeedback-and-cognitive-behavioural-group-therapy-in-adults-with-attention-deficit-hyperactivity-disorder-a-triple-blind-randomised-controlled-trial
#9
Michael Schönenberg, Eva Wiedemann, Alexander Schneidt, Jonathan Scheeff, Alexander Logemann, Philipp M Keune, Martin Hautzinger
BACKGROUND: Many studies suggest that electroencephalographic (EEG) neurofeedback might be beneficial in the treatment of attention-deficit hyperactivity disorder (ADHD). However, numbers of well controlled studies are low and neurofeedback techniques are regarded as highly controversial. The present trial examined the efficacy (compared with sham neurofeedback) and efficiency (compared with meta-cognitive therapy) of a standard EEG neurofeedback protocol in adults with ADHD. METHODS: We did a concurrent, triple-blind, randomised, controlled trial using authorised deception in adults with ADHD from one centre (University of Tübingen) in Tübingen, Germany...
August 9, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28800340/reducing-the-rate-of-misdiagnosis-in%C3%A2-patients-with-chronic-disorders-of%C3%A2-consciousness-is-there-a-place-for-audiovisual-stimulation
#10
Antonino Naro, Antonino Leo, Rocco Bruno, Antonino Cannavò, Antonio Buda, Alfredo Manuli, Alessia Bramanti, Placido Bramanti, Rocco Salvatore Calabrò
BACKGROUND: The patients with chronic Disorders of Consciousness (DoC) mostly present with extremely challenging differential diagnosis. The advanced analysis of electroencephalographic (EEG) signals induced by brain stimulation paradigms may provide an appropriate approach to differentiate patients with DoC, besides the clinical assessment. OBJECTIVE: This study was performed with an objective of identifying residual brain network perturbations following an innovative, non-invasive audiovisual stimulation protocol, which could be related to behavioral responsiveness in patients with DoC...
August 11, 2017: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/28798683/enhanced-gamma-activity-and-cross-frequency-interaction-of-resting-state-electroencephalographic-oscillations-in-patients-with-alzheimer-s-disease
#11
Jing Wang, Yuxing Fang, Xiao Wang, Huichao Yang, Xin Yu, Huali Wang
Cognitive impairment, functional decline and behavioral symptoms that characterize Alzheimer's disease (AD) are associated with perturbations of the neuronal network. The typical electroencephalographic (EEG) features in AD patients are increased delta or theta rhythm and decreased alpha or beta rhythm activities. However, considering the role of cross-frequency couplings in cognition, the alternation of cross-frequency couplings in AD patients is still obscure. This study aims to explore the interaction dynamics between different EEG oscillations in AD patients...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28795168/changes-in-brain-behavior-relationships-following-a-3-month-pilot-cognitive-intervention-program-for-adults-with-traumatic-brain-injury
#12
S Porter, I J Torres, W Panenka, Z Rajwani, D Fawcett, A Hyder, N Virji-Babul
Facilitating functional recovery following brain injury is a key goal of neurorehabilitation. Direct, objective measures of changes in the brain are critical to understanding how and when meaningful changes occur, however, assessing neuroplasticity using brain based results remains a significant challenge. Little is known about the underlying changes in functional brain networks that correlate with cognitive outcomes in traumatic brain injury (TBI). The purpose of this pilot study was to assess the feasibility of an intensive three month cognitive intervention program in individuals with chronic TBI and to evaluate the effects of this intervention on brain-behavioral relationships...
August 2017: Heliyon
https://www.readbyqxmd.com/read/28791477/electroencephalographic-effect-of-age-adjusted-1-mac-desflurane-and-sevoflurane-in-young-middle-aged-and-elderly-patients
#13
Shinya Kanazawa, Yutaka Oda, Chika Maeda, Ryu Okutani
PURPOSE: We examined the hypothesis that 1 minimum alveolar concentration (MAC) of desflurane and sevoflurane provides different depth of anesthesia. METHODS: One hundred and twenty young (20-30 years), middle-aged (31-65 years), and elderly (66-80 years) patients were randomly allocated to receive either desflurane or sevoflurane (n = 20, each group). General anesthesia was induced with propofol 2 mg/kg bolus and remifentanil 0.25 µg/kg/min, which was stopped after tracheal intubation...
August 8, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28790884/the-effect-of-electroencephalogram-eeg-reference-choice-on-information-theoretic-measures-of-the-complexity-and-integration-of-eeg-signals
#14
Logan T Trujillo, Candice T Stanfield, Ruben D Vela
Converging evidence suggests that human cognition and behavior emerge from functional brain networks interacting on local and global scales. We investigated two information-theoretic measures of functional brain segregation and integration-interaction complexity C I (X), and integration I(X)-as applied to electroencephalographic (EEG) signals and how these measures are affected by choice of EEG reference. CI(X) is a statistical measure of the system entropy accounted for by interactions among its elements, whereas I(X) indexes the overall deviation from statistical independence of the individual elements of a system...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28790302/formation-and-suppression-of-acoustic-memories-during-human-sleep
#15
Thomas Andrillon, Daniel Pressnitzer, Damien Léger, Sid Kouider
Sleep and memory are deeply related, but the nature of the neuroplastic processes induced by sleep remains unclear. Here, we report that memory traces can be both formed or suppressed during sleep, depending on sleep phase. We played samples of acoustic noise to sleeping human listeners. Repeated exposure to a novel noise during Rapid Eye Movements (REM) or light non-REM (NREM) sleep leads to improvements in behavioral performance upon awakening. Strikingly, the same exposure during deep NREM sleep leads to impaired performance upon awakening...
August 8, 2017: Nature Communications
https://www.readbyqxmd.com/read/28783808/recrudescence-of-deficits-after-stroke-clinical-and-imaging-phenotype-triggers-and-risk-factors
#16
Mehmet A Topcuoglu, Esen Saka, Scott B Silverman, Lee H Schwamm, Aneesh B Singhal
Importance: Reemergence of previous stroke-related deficits (or poststroke recrudescence [PSR]) is an underrecognized and inadequately characterized phenomenon. Objective: To investigate the clinical features, triggers, and risk factors for PSR. Design, Setting, and Participants: This retrospective study incorporated a crossover cohort study to identify triggers and a case-control study to identify risk factors. The study used the Massachusetts General Hospital Research Patient Data Repository to identify patients for the period January 1, 2000, to November 30, 2015, who had a primary or secondary diagnosis of cerebrovascular disease, who underwent magnetic resonance imaging of the brain at least once, and whose inpatient or outpatient clinician note or discharge summary stated the term recrudescence...
August 7, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28783638/cmos-ultralow-power-brain-signal-acquisition-front-ends-design-and-human-testing
#17
Alireza Karimi-Bidhendi, Omid Malekzadeh-Arasteh, Mao-Cheng Lee, Colin M McCrimmon, Po T Wang, Akshay Mahajan, Charles Yu Liu, Zoran Nenadic, An H Do, Payam Heydari
Two brain signal acquisition (BSA) front-ends incorporating two CMOS ultralow power, low-noise amplifier arrays and serializers operating in mosfet weak inversion region are presented. To boost the amplifier's gain for a given current budget, cross-coupled-pair active load topology is used in the first stages of these two amplifiers. These two BSA front-ends are fabricated in 130 and 180 nm CMOS processes, occupying 5.45 mm (2) and 0.352 mm (2) of die areas, respectively (excluding pad rings). The CMOS 130-nm amplifier array is comprised of 64 elements, where each amplifier element consumes 0...
August 1, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28782683/unidirectional-brain-to-muscle-connectivity-reveals-motor-cortex-control-of-leg-muscles-during-stereotyped-walking
#18
Fiorenzo Artoni, Chiara Fanciullacci, Federica Bertolucci, Alessandro Panarese, Scott Makeig, Silvestro Micera, Carmelo Chisari
In lower mammals, locomotion seems to be mainly regulated by subcortical and spinal networks. On the contrary, recent evidence suggests that in humans the motor cortex is also significantly engaged during complex locomotion tasks. However, a detailed understanding of cortical contribution to locomotion is still lacking especially during stereotyped activities. Here, we show that cortical motor areas finely control leg muscle activation during treadmill stereotyped walking. Using a novel technique based on a combination of Reliable Independent Component Analysis, source localization and effective connectivity, and by combining electroencephalographic (EEG) and electromyographic (EMG) recordings in able-bodied adults we were able to examine for the first time cortical activation patterns and cortico-muscular connectivity including information flow direction...
August 4, 2017: NeuroImage
https://www.readbyqxmd.com/read/28779924/effect-of-essential-oil-and-supercritical-carbon-dioxide-extract-from-the-root-of-angelica-gigas-on-human-eeg-activity
#19
Kandhasamy Sowndhararajan, Min Seo, Minju Kim, Heeyeon Kim, Songmun Kim
OBJECTIVES: The present study aimed to investigate the effect of inhalation of essential oil (EO) and supercritical carbon dioxide extract (SC-CO2) from the root of A. gigas on human electroencephalographic (EEG) activity. MATERIALS AND METHODS: For this purpose, the EO was obtained from the root of A. gigas by steam distillation and SC-CO2 was obtained at 50 °C and 400 bar for 1 h. The EEG readings were recorded using the QEEG-8 system from 8 electrode sites according to the International 10-20 system...
August 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/28778058/response-to-adrenocorticotropic-in-attention-deficit-hyperactivity-disorder-like-symptoms-in-electrical-status-epilepticus-in-sleep-syndrome-is-related-to-electroencephalographic-improvement-a-retrospective-study
#20
Attila Altunel, Emine Özlem Altunel, Ali Sever
INTRODUCTION: Encephalopathy with electrical status epilepticus in sleep (ESES) syndrome is a rare epilepsy syndrome of childhood that is characterized by sleep-induced epileptiform discharges and problems with cognition or behavior. The neuropsychiatric symptoms in ESES syndrome, among which the ADHD-like symptoms are prominent, bear a close resemblance to symptoms in various developmental disorders. Positive response to adrenocorticotropic hormone (ACTH) is associated with the normalization of the EEG and improvement of neuropsychiatric function...
August 1, 2017: Epilepsy & Behavior: E&B
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