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https://www.readbyqxmd.com/read/28646302/t-regulatory-cells-exhibit-a-biphasic-response-to-prolonged-endurance-exercise-in-humans
#1
Tom Clifford, Matthew J Wood, Philip Stocks, Glyn Howatson, Emma J Stevenson, Catharien M U Hilkens
PURPOSE: T-regulatory cells (Tregs) are a sub-population of lymphocytes that act to suppress aberrant immune responses. We investigated changes in the numbers of naïve and terminally differentiated Tregs in the peripheral blood to establish their role in the immuno-suppressive response to prolonged exercise. METHODS: Blood was drawn from seventeen experienced runners (age 40 ± 12 years; height 1.75 ± 0.08 m; mass 71.4 ± 10.8 kg) before, ~1 h after (POST-1h), and on the day following the marathon (POST-1d)...
June 23, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28641058/acute-kinematics-changes-in-marathon-runners-using-different-footwear
#2
Tania Socorro Amorim Soares, Camila Fonseca de Oliveira, Federico Pizzuto, Rui Manuel Garganta, João Paulo Vila-Boas, Mario Casimiro da Anunciação Paiva
The effects of running with or without shoes on injury prevention have been extensively studied, and several investigations have assessed biomechanical differences between them. However, findings are not consensual and further insights on biomechanical load associated with differently shod or barefoot conditions may be needed. This study aimed to observe if habitually shod marathon runners show acute alterations when running barefoot or with minimalist shoes, and to determine whether the running kinematical adaptations of wearing minimalist shoes were similar to barefoot running...
June 22, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28630571/predictive-variables-of-half-marathon-performance-for-male-runners
#3
Josué Gómez-Molina, Ana Ogueta-Alday, Jesus Camara, Christoper Stickley, José A Rodríguez-Marroyo, Juan García-López
The aims of this study were to establish and validate various predictive equations of half-marathon performance. Seventy-eight half-marathon male runners participated in two different phases. Phase 1 (n = 48) was used to establish the equations for estimating half-marathon performance, and Phase 2 (n = 30) to validate these equations. Apart from half-marathon performance, training-related and anthropometric variables were recorded, and an incremental test on a treadmill was performed, in which physiological (VO2max, speed at the anaerobic threshold, peak speed) and biomechanical variables (contact and flight times, step length and step rate) were registered...
June 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28623650/the-incidence-of-dissociated-liners-in-4-751-consecutive-total-hip-arthroplasties-using-pinnacle-polyethylene-acetabular-liners
#4
Richard J Napier, Owen Diamond, Chris K J O'Neill, Seamus O'Brien, David E Beverland
INTRODUCTION: Acetabular liner dissociation is a complication exclusive to modular designs. We present a single surgeon series of 8 polyethylene liner dissociations with the Pinnacle Acetabular System (DePuy Orthopaedics) from over 4,750 cases. We also present a review of the literature and data from the UK National Joint Registry (NJR) on dissociation in total hip arthroplasty (THA). METHODS: The Pinnacle Acetabular System has been used exclusively by the senior author since April 2003, and to date 5,882 have been implanted (837 ceramic liners, 4,751 polyethylene liners (1,606 Enduron/3,145 Marathon) and 294 metal liners)...
June 14, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28611674/is-marathon-training-harder-than-the-ironman-training-an-eco-method-comparison
#5
Jonathan Esteve-Lanao, Diego Moreno-Pérez, Claudia A Cardona, Eneko Larumbe-Zabala, Iker Muñoz, Sergio Sellés, Roberto Cejuela
Purpose: To compare the absolute and relative training load of the Marathon (42k) and the Ironman (IM) training in recreational trained athletes. Methods: Fifteen Marathoners and Fifteen Triathletes participated in the study. Their performance level was the same relative to the sex's absolute winner at the race. No differences were presented neither in age, nor in body weight, height, BMI, running VO2max max, or endurance training experience (p > 0.05). They all trained systematically for their respective event (IM or 42k)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28595134/fatigue-induced-dissociation-between-rate-of-force-development-and-maximal-force-across-repeated-rapid-contractions
#6
Gennaro Boccia, Davide Dardanello, Cantor Tarperi, Luca Festa, Antonio La Torre, Barbara Pellegrini, Federico Schena, Alberto Rainoldi
We examined whether the presence of fatigue induced by prolonged running influenced the time courses of force generating capacities throughout a series of intermittent rapid contractions. Thirteen male amateur runners performed a set of 15 intermittent isometric rapid contractions of the knee extensor muscles, (3s/5s on/off) the day before (PRE) and immediately after (POST) a half marathon. The maximal voluntary contraction force, rate of force development (RFDpeak), and their ratio (relative RFDpeak) were calculated...
June 5, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28591543/influence-of-polyphenol-rich-diet-on-exercise-induced-immunomodulation-in-male-endurance-athletes
#7
Korbinian Lackermair, Johannes Scherr, Georg Waidhauser, Heiko Methe, Eva Hoster, David C Nieman, Alan Hanley, Sebastian Clauss, Martin Halle, Thomas Nickel
<u>Introduction:</u> Stress is associated with increased susceptibility to infection. We investigated if the mechanism involves immunomodulation of dendritic cells and whether this can be inhibited by a polyphenol-rich diet. <u>Methods:</u> Blood samples were taken from a total of 100 male endurance athletes at five time points around a marathon run: four weeks before, during one week before, and immediately, 24hours and 72hours after. Participants were randomized into two double blinded groups...
June 7, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28587488/running-multiple-marathons-is-not-a-risk-factor-for-premature-subclinical-vascular-impairment
#8
Axel Pressler, Christiane Suchy, Tasja Friedrichs, Sophia Dallinger, Viola Grabs, Bernhard Haller, Martin Halle, Johannes Scherr
Background In contrast to the well-accepted benefits of moderate exercise, recent research has suggested potential deleterious effects of repeated marathon running on the cardiovascular system. We thus performed a comprehensive analysis of markers of subclinical vascular damage in a cohort of runners having finished multiple marathon races successfully. Design This was a prospective, observational study. Methods A total of 97 healthy male Munich marathon participants (mean age 44 ± 10 years) underwent detailed training history, cardiopulmonary exercise testing for assessment of peak oxygen uptake, ultrasound for assessment of intima-media-thickness as well as non-invasive assessments of ankle-brachial index, augmentation index, pulse wave velocity and reactive hyperaemia index...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28581678/ttn-genotype-is-associated-with-fascicle-length-and-marathon-running-performance
#9
Georgina K Stebbings, Alun G Williams, Adam J Herbert, Sarah J Lockey, Shane M Heffernan, Robert M Erskine, Christopher I Morse, Stephen H Day
Titin provides a molecular blueprint for muscle sarcomere assembly and sarcomere length can vary according to titin isoform expression. If variations in sarcomere length influence muscle fascicle length, this may provide an advantage for running performance. Thus the aim of this study was to investigate if the titin (TTN) rs10497520 polymorphism was associated with muscle fascicle length in recreationally active men (RA; n = 137) and marathon personal best time in male marathon runners (MR; n = 141). Fascicle length of the vastus lateralis was assessed in vivo using B-mode ultrasonography at 50% of muscle length in RA...
June 5, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28574286/changes-of-intima-media-thickness-in-marathon-runners-a-mid-term-follow-up
#10
Jan Müller, Valeria Dahm, Elke S Lorenz, Axel Pressler, Bernhard Haller, Viola Grabs, Martin Halle, Johannes Scherr
Objective Carotid intima-media thickness (IMT) is used to assess cardiovascular risk and progression of atherosclerosis. It is known that regular physical activity of moderate intensity has beneficial effects on the vasculature. However, it is still discussed controversially whether prolonged exercise, including participation in exhaustive competitive sports such as long-distance races, has also beneficial effects or might even be harmful regarding the cardiovascular system. Patients and methods Thirty-eight male marathon runners (45...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28569594/a-new-step-in-the-marathon-of-understanding-chronic-rejection-after-lung-transplantation
#11
Bart Vanaudenaerde, Stijn Verleden, Arne Neyrinck, Geert Verleden, Robin Vos
No abstract text is available yet for this article.
June 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28565852/oxidation-of-human-serum-albumin-exhibits-inter-individual-variability-after-an-ultra-marathon-mountain-race
#12
Ypatios Spanidis, Alexandros Priftis, Dimitrios Stagos, George A Stravodimos, Demetres D Leonidas, Demetrios A Spandidos, Aristides M Tsatsakis, Demetrios Kouretas
The aim of this study was to examine the oxidation of human serum albumin (HSA) caused by oxidative stress following exhaustive and demanding exercise, such as an ultra-marathon race. For this purpose, blood samples from 12 adult runners who underwent a 103 km mountain ultra-marathon race were collected before the race, and also at 24, 48 and 72 h post-race. HSA was partially purified using affinity chromatography and consequently subjected to western blot analysis in order to determine the levels of disulfide dimers indicating oxidation...
May 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28562290/lessons-from-the-2013-boston-marathon-incorporating-residents-into-institutional-emergency-plans
#13
REVIEW
Katherine R Schlosser, Jessica K Creedon, Kenneth A Michelson, Catherine D Michelson
No abstract text is available yet for this article.
May 25, 2017: Pediatrics
https://www.readbyqxmd.com/read/28538304/a-performance-analysis-of-a-stand-up-paddle-board-marathon-race
#14
Ben L Schram, Wayne A Hing, Mike Climstein, James W Furness
Stand-up paddle boarding (SUP) is a rapidly growing sport and recreational activity in which little scientific research exists. A review of the literature failed to identify a single article pertaining to the physiological demands of SUP competition. The purpose of this study was to conduct a performance analysis of a national-level SUP marathon race. Ten elite SUP athletes (6 male and 4 female athletes) were recruited from the Stand Up Paddle Surfing Association of Australia to have their race performance in the Australian Titles analyzed...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28535286/invited-commentary-is-strenuous-activity-good-for-you-the-legacy-of-ralph-paffenbarger
#15
Lewis H Kuller
Ralph Paffenbarger, Jr, MD, DrPH (1922-2007), was initially trained as an infectious disease epidemiologist at the Johns Hopkins School of Hygiene and Public Health (now the Bloomberg School of Public Health). He was the first Epidemiology Intelligence Service officer in the first Epidemiology Intelligence Service class. He joined the National Heart Institute (now the National Heart, Lung, and Blood Institute) in its very early days and later became a faculty member at Stanford University and Harvard University...
June 1, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28532238/the-age-related-performance-decline-in-marathon-cross-country-skiing-the-engadin-ski-marathon
#16
Pantelis Theodoros Nikolaidis, Beat Knechtle
Demographic and performance data from 197,825 athletes competing in "Engadin Ski Marathon" between 1998 and 2016 were analysed. When all finishers per age group were considered, there was no gender difference in time (2:59:00 in women versus 2:59:09 h:min:s in men; P = 0.914, η(2) < 0.001) and the main effect of age group on time was trivial (P < 0.001, η(2) = 0.007). When the top 10 finishers per age group were considered, men were faster than women (1:27:32 versus 1:34:19 h:min:s, respectively; P < 0...
May 22, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28513880/unstable-rocker-shoes-promote-recovery-from-marathon-induced-muscle-damage-in-novice-runners
#17
Kento Nakagawa, Takayuki Inami, Takahisa Yonezu, Yuta Kenmotsu, Takaya Narita, Yasuo Kawakami, Kazuyuki Kanosue
We recently reported that wearing unstable rocker shoes (Masai Barefoot Technology: MBT) may enhance recovery from marathon race induced fatigue. However, this earlier study only utilized a questionnaire. In the present study, we evaluated MBT utilizing objective physiological measures of recovery from marathon induced muscle damages. Twenty-five university student novice runners were divided into two groups. After running a full marathon, one group wore MBT shoes (MBT group), and the control group (CON) wore ordinary shoes daily for one week following the race...
May 17, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28505411/quantification-of-endogenous-cholesterol-in-human-serum-on-paper-using-direct-analysis-in-real-time-mass-spectrometry
#18
Hua-Yi Hsieh, Li-Hua Li, Ren-Yu Hsu, Wei-Fong Kao, Ying-Chen Huang, Cheng-Chih Hsu
Blood testing for endogenous small metabolites to determine physiological and biochemical states is routine for laboratory analysis. Here we demonstrate that by combining the commercial direct analysis in real time (DART) ion source with an ion trap mass spectrometer, native cholesterol in its free alcohol form is readily detected from a few hundred nanoliters of human serum loaded onto chromatography paper. Deuterium-labeled cholesterol was used as the internal standard to obtain the absolute quantity of the endogenous cholesterol...
June 6, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28503322/changes-in-oxidized-ldl-during-a-half-marathon-in-athletes-with-spinal-cord-injuries
#19
Toshihito Mitsui, Tomoyuki Ito, Yusuke Sasaki, Takashi Kawasaki, Takeshi Nakamura, Yukihide Nishimura, Tatsuru Ibusuki, Yukiharu Higuchi, Sayoko Hosoe, Fumiaki Ito, Fumihiro Tajima
INTRODUCTION: We reported previously that exercise significantly increases plasma adrenaline and oxidized low-density lipoprotein (oxLDL) in healthy subjects but not in persons with spinal cord injury (SCI). Since oxLDL and adrenaline levels are associated with oxidant/antioxidant balance, and exercise training elicits production of reactive oxygen species, we elucidated the effects of exercise on adrenaline, oxidant/antioxidant balance and oxLDL in individuals with SCI. CASE PRESENTATION: Eight subjects with cervical spinal cord injury (CSCI) and nine subjects with lower lesion of SCI (lower SCI (LSCI)) participated in a wheelchair half marathon race, and blood samples were collected before (pre), immediately after (post) and 1 h after the race (post 1 h)...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28498221/optimizing-marathon-race-safety-using-an-incident-command-post-strategy
#20
Katherine V Yao, Christopher Troyanos, Pierre D'Hemecourt, William O Roberts
No abstract text is available yet for this article.
May 2017: Current Sports Medicine Reports
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