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https://www.readbyqxmd.com/read/28227658/evaluating-the-deflection-of-dexterous-continuum-manipulators-with-unevenly-distributed-compliant-joints
#1
Anzhu Gao, Ryan J Murphy, Hao Liu, Iulian Iordachita, Mehran Armand, Anzhu Gao, Ryan J Murphy, Hao Liu, Iulian Iordachita, Mehran Armand, Hao Liu, Anzhu Gao, Iulian Iordachita, Mehran Armand, Ryan J Murphy
Dexterous continuum manipulators (DCMs) offer great potential for increasing instrument reach in minimally-invasive surgical procedures. We previously designed and fabricated a tendon driven DCM with a large instrument channel and evenly distributed compliant joints for minimally-invasive skull base surgery and the treatment of osteolysis during hip revision surgery. The evenly distributed compliant joints, in some cases, may limit the reach of the DCM during lesion removal. In this paper, we propose a finite element analysis (FEA) method for optimizing the distribution of the compliant joints based on treatment space requirements determined preoperatively...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227655/development-of-a-snake-like-dexterous-manipulator-for-skull-base-surgery
#2
Suat Coemert, Anzhu Gao, John P Carey, Mattias F Traeger, Russell H Taylor, Tim C Lueth, Mehran Armand, Suat Coemert, Anzhu Gao, John P Carey, Mattias F Traeger, Russell H Taylor, Tim C Lueth, Mehran Armand, Anzhu Gao, Russell H Taylor, Mattias F Traeger, Mehran Armand, Suat Coemert, Tim C Lueth, John P Carey
Petrous apex lesions constitute considerable surgical challenges due to their location in the skull base and close relationship with critical structures such as inner ear, carotid arteries, facial nerves and jugular bulb. These lesions often cannot be treated completely with rigid tools due to the limited accessibility. We are aiming to develop a snake-like manipulator to assist surgeons with the infralabyrinthine treatment of petrous apex lesions with increased dexterity. This snake-like dexterous manipulator (SDM) with 3...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227376/electrocardiogram-reconstruction-from-high-resolution-voltage-optical-mapping
#3
Ilija Uzelac, Conner Herndon, James Farmer, Flavio Fenton, Ilija Uzelac, Conner Herndon, James Farmer, Flavio Fenton, Ilija Uzelac, Conner Herndon, James Farmer, Flavio Fenton
Electrocardiogram recordings during opucal mapping experiments in heart tissue are commonly used tu monitor the health of the preparation and to obtain dominant frequencies during arrhythmic and defibrillatory studies. However the use of ECG reconstructed from optical mapping is seldom used and to date it has not been strictly validated. In this manuscript we present the first detailed validation and comparison of Optical Mapping ECG, or OM-ECG, with standard ECG recordings by calculating the electrostatic potential in space as a function of the voltage measured optically and describe the different approximations that can be used to obtain unipolar or bipolar ECG recordings...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227085/an-object-oriented-model-of-the-cardiopulmonary-system-with-emphasis-on-the-gravity-effect
#4
Chuong Ngo, Silvia Briones Herranz, Berno Misgeld, Thomas Vollmer, Steffen Leonhardt, Chuong Ngo, Silvia Briones Herranz, Berno Misgeld, Thomas Vollmer, Steffen Leonhardt, Thomas Vollmer, Steffen Leonhardt, Chuong Ngo, Berno Misgeld
We introduce a novel comprehensive model of the cardiopulmonary system with emphasis on perfusion and ventilation distribution along the vertical thorax axis under the gravity effect. By using an object-oriented environment, the complex physiological system can be represented by a network of electrical, lumped-element compartments. The lungs are divided into three zones: upper, middle, and lower zone. Blood flow increases with the distance from the apex to the base of the lungs. The upper zone is characterized by a complete collapse of the pulmonary capillary vasculature; thus, there is no flow in this zone...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227029/automated-ongoing-data-validation-and-quality-control-of-multi-institutional-studies
#5
Lara J Kanbar, Wissam Shalish, Doina Precup, Karen Brown, Guilherme M Sant'Anna, Robert E Kearney, Lara J Kanbar, Wissam Shalish, Doina Precup, Karen Brown, Guilherme M Sant'Anna, Robert E Kearney, Robert E Kearney, Lara J Kanbar, Wissam Shalish, Doina Precup, Karen Brown, Guilherme M Sant'anna
This paper addresses the problem of ensuring the validity and quality of data in ongoing multi-disciplinary studies where data acquisition spans several geographical sites. It describes an automated validation and quality control procedure that requires no user supervision and monitors data acquired from different locations before analysis. The procedure is illustrated for the Automated Prediction of Extubation readiness (APEX) project in preterm infants, where acquisition of clinical and cardiorespiratory data occurs at 6 sites using different equipment and personnel...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226676/quantitative-evaluation-of-alveolar-bone-resorption-on-dental-panoramic-radiographs-by-standardized-dentition-image-transformation-and-probability-estimation
#6
Chisako Muramtsu, Ryo Takahashi, Tatsuro Hayashi, Takeshi Hara, Tatsumasa Fukui, Akitoshi Katsumata, Hiroshi Fujita, Chisako Muramtsu, Ryo Takahashi, Tatsuro Hayashi, Takeshi Hara, Tatsumasa Fukui, Akitoshi Katsumata, Hiroshi Fujita, Akitoshi Katsumata, Ryo Takahashi, Tatsuro Hayashi, Takeshi Hara, Chisako Muramtsu, Tatsumasa Fukui, Hiroshi Fujita
Alveolar bone resorption, which can be observed on dental panoramic radiographs (DPRs), is one of the most important signs of the progression of periodontal disease. However, quantitative and consistent evaluation of alveolar bone resorption is labor intense, because of a large number of DPR examinations performed each year. In our previous study, we developed an automated scheme for detection of three lines, corresponding to an occlusion line, an alveolar line and a root apex line, to measure the alveolar bone ratio (ABR), which may be useful to dentists in early detection of periodontal disease...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224424/dynamic-characteristic-mechanism-of-atrial-septal-defect-using-real-time-three-dimensional-echocardiography-and-evaluation-of-right-ventricular-functions
#7
Gao-Wa Sharen, Jun Zhang, Chuan Qin, Qing Lv
The dynamic characteristics of the area of the atrial septal defect (ASD) were evaluated using the technique of real-time three-dimensional echocardiography (RT 3DE), the potential factors responsible for the dynamic characteristics of the area of ASD were observed, and the overall and local volume and functions of the patients with ASD were measured. RT 3DE was performed on the 27 normal controls and 28 patients with ASD. Based on the three-dimensional data workstations, the area of ASD was measured at P wave vertex, R wave vertex, T wave starting point, and T wave terminal point and in the T-P section...
February 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28224002/secretion-and-endocytosis-in-pollen-tubes-models-of-tip-growth-in-the-spot-light
#8
REVIEW
Gleb Grebnev, Maria Ntefidou, Benedikt Kost
Pollen tube tip growth is a widely used model ideally suited to study cellular processes underlying polarized cell expansion. Local secretion supplying material for plasma membrane (PM) and cell wall extension is essential for this process. Cell wall biogenesis requires fusion of secretory vesicles with the PM at an about 10× higher rate than PM extension. Excess material is therefore incorporated into the PM, which needs to be reinternalized through endocytosis. The classical model of tip growth proposes that exocytosis occurs at the apex and that newly incorporated PM material is transported to adjacent lateral regions, where excess material is endocytically recycled...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28223530/differential-tor-activation-and-cell-proliferation-in-arabidopsis-root-and-shoot-apexes
#9
Xiaojuan Li, Wenguo Cai, Yanlin Liu, Hui Li, Liwen Fu, Zengyu Liu, Lin Xu, Hongtao Liu, Tongda Xu, Yan Xiong
The developmental plasticity of plants relies on the remarkable ability of the meristems to integrate nutrient and energy availability with environmental signals. Meristems in root and shoot apexes share highly similar molecular players but are spatially separated by soil. Whether and how these two meristematic tissues have differential activation requirements for local nutrient, hormone, and environmental cues (e.g., light) remain enigmatic in photosynthetic plants. Here, we report that the activation of root and shoot apexes relies on distinct glucose and light signals...
February 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28222332/acquisition-of-vowel-articulation-in-childhood-investigated-by-acoustic-to-articulatory-inversion
#10
Hiroki Oohashi, Hama Watanabe, Gentaro Taga
While the acoustical features of speech sounds in children have been extensively studied, limited information is available as to their articulation during speech production. Instead of directly measuring articulatory movements, this study used an acoustic-to-articulatory inversion model with scalable vocal tract size to estimate developmental changes in articulatory state during vowel production. Using a pseudo-inverse Jacobian matrix of a model mapping seven articulatory parameters to acoustic ones, the formant frequencies of each vowel produced by three Japanese children over time at ages between 6 and 60 months were transformed into articulatory parameters...
February 18, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28222145/cataract-surgery-causes-biomechanical-alterations-to-the-eye-detectable-by-corvis-st-tonometry
#11
Yoshitake Kato, Shunsuke Nakakura, Ryo Asaoka, Kanae Matsuya, Yuki Fujio, Yoshiaki Kiuchi
PURPOSE: Modern cataract surgery is generally considered to bring about modest and sustained intraocular pressure (IOP) reduction. However, the pathophysiological mechanism for this remains unclear. Moreover, a change in ocular biomechanical properties after surgery can affect the measurement of IOP. The aim of the study is to investigate ocular biomechanics, before and following cataract surgery, using Corvis ST tonometry (CST). PATIENTS AND METHODS: Fifty-nine eyes of 59 patients with cataract were analyzed...
2017: PloS One
https://www.readbyqxmd.com/read/28222067/designation-and-validation-of-a-posterior-anatomical-plate-for-the-anterior-column-of-the-acetabulum
#12
Lifeng Zhang, Chuangxin Lin, Shenglu Cao, Yiran Wang, Geng Peng, Yongqiang Xu, Yongzeng Feng, Gang Wang
BACKGROUND Surgical treatment of acetabular fractures is one of the greatest challenges for orthopedic surgeons. Fixation of most displaced fractures requires extensive exposure, which may lead to complications, including blood loss, neural or vascular injury, postoperative infection, wound healing problems, and heterotopic bone formation. MATERIAL AND METHODS This study was conducted to certify an anatomic plate with an anterior column lag screw guiding device to repair the posterior acetabulum. Complete pelvic spiral computed tomography (CT) scan data were collected from 56 patients...
February 21, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28219755/a-congenital-diverticulum-of-the-left-ventricular-apex-manifested-by-stroke-and-recurrent-ventricular-tachycardia
#13
Gabriela Dostálová, Tomáš Paleček, Petr Kuchynka, Štěpán Havránek, Martin Mašek, Zuzana Hlubocká, Debora Karetová, Dan Wichterle, Jaroslava Dušková, Jaroslav Lindner, Aleš Linhart
Ventricular outpouchings include acquired abnormalities (aneurysms and pseudoaneurysms) and congenital ventricular diverticula (CVD). CVD represent rare cardiac pathologies. Although CVD is often associated with other cardiac and extracardiac congenital anomalies, it can also be incidentally observed in otherwise healthy subjects. CVD may lead to significant morbidity and even have lethal consequences. We describe a case of arrhythmogenic left ventricle (LV) apical CVD revealed by cardiac magnetic resonance imaging (CMRI) after being initially overlooked by echocardiography...
February 4, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28217540/correlating-the-clinical-assessment-of-impacted-mandibular-third-molars-with-panoramic-radiograph-and-intraoral-periapical-radiograph
#14
P Vani Priya, Fazil A Nasyam, M Ramprasad, Narendra V Penumatsa, Syed Akifuddin, Sandeep
AIMS AND OBJECTIVES: This study was conducted to compare the clinical assessment of impacted third molars of mandible with panaromic radiograph (OPG) and intraoral periapical radiograph (IOPA) and to assess the efficacy of IOPA and. Moreover, we corroborated the OPG and IOPA findings of impacted mandiblar third molar root apex to inferior alveolar canal. MATERIALS AND METHODS: A total of 200 patients with pericoronitis were examined who were indicated for surgical extraction, among which 50 patients were selected for the study...
December 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28216760/vanishing-bone-disease-of-chest-wall-and-spine-with-kyphoscoliosis-and-neurological-deficit-a-case-report-and-review-of-literature
#15
Sudhir Kumar Srivastava, Rishi Anil Aggarwal, Pradip Sharad Nemade, Sunil Krishna Bhoale
Vanishing bone disease is an extremely rare disorder of unknown etiology characterized by idiopathic osteolysis of bone. We describe a case of vanishing bone disease of chest wall and spine with kyphoscoliosis and neurological deficit. A 17-year-old male presented with gradually progressive deformity of back and dorsal compressive myelopathy with nonambulatory power in lower limbs. Radiographs revealed absent 4(th)-7(th) ribs on the right side with dorsal kyphoscoliosis and severe canal narrowing at the apex...
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28214944/the-vascular-plants-open-system-of-growth
#16
REVIEW
Alice Basile, Marco Fambrini, Claudio Pugliesi
What is fascinating in plants (true also in sessile animals such as corals and hydroids) is definitely their open and indeterminate growth, as a result of meristematic activity. Plants as well as animals are characterized by a multicellular organization, with which they share a common set of genes inherited from a common eukaryotic ancestor; nevertheless, circa 1.5 billion years of evolutionary history made the two kingdoms very different in their own developmental biology. Flowering plants, also known as angiosperms, arose during the Cretaceous Period (145-65 million years ago), and up to date, they count around 235,000 species, representing the largest and most diverse group within the plant kingdom...
February 18, 2017: Development Genes and Evolution
https://www.readbyqxmd.com/read/28210715/feasibility-and-reproducibility-of-two-dimensional-wall-motion-tracking-wmt-in-fetal-echocardiography
#17
Christian Enzensberger, Friederike Achterberg, Jan Degenhardt, Aline Wolter, Oliver Graupner, Johannes Herrmann, Roland Axt-Fliedner
Objective The primary objective of this study was to determine the feasibility and reproducibility of 2-dimensional speckle tracking imaging based on the wall motion tracking (WMT) technique in fetal echocardiography. The secondary objective was to compare left and right ventricular global and segmental longitudinal peak strain values. Methods A prospective cross-sectional study was performed. Global and segmental longitudinal peak strain values of the left ventricle (LV) and right ventricle (RV) were assessed prospectively...
February 2017: Ultrasound International Open
https://www.readbyqxmd.com/read/28210446/differences-between-panoramic-and-cone-beam-ct-in-the-surgical-evaluation-of-lower-third-molars
#18
Ruggero Rodriguez Y Baena, Riccardo Beltrami, Angelo Tagliabo, Silvana Rizzo, Saturnino-Marco Lupi
BACKGROUND: The aim of this study was to evaluate the ability to identify the contiguity between the root of the mandibular third molar and the mandibular canal (MC) in panoramic radiographs compared with Cone Beam-CT. MATERIAL AND METHODS: Panoramic radiographs of 326 third molars and CBCT radiographs of 86 cases indicated for surgery and considered at risk were evaluated. The following signs were assessed in panoramic radiographs as risk factors: radiolucent band, loss of MC border, change in MC direction, MC narrowing, root narrowing, root deviation, bifid apex, superimposition, and contact between the root third molar and the MC...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28210439/effect-of-endoactivator-and-er-cr-ysgg-laser-activation-of-qmix-as-final-endodontic-irrigant-on-sealer-penetration-a-confocal-microscopic-study
#19
Sarika Chaudhry, Sudha Yadav, Sangeeta Talwar, Mahesh Verma
BACKGROUND: Through chemomechanical debridement of the root canal is a primary requisite for successful endodontic therapy. Thus the aim of this study was to evaluate the effects of using QmiX alone, QmiX with EndoActivator and QmiX with Er,Cr:YSGG laser for final irrigation on sealer penetration into the dentinal tubules. MATERIAL AND METHODS: 75 extracted human mandibular premolar teeth were treated with sodium hypochlorite (NaOCl) irrigation. The samples were divided into 5 groups according to the final irrigation solution used: (1) 17% EDTA and 2...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28209731/transport-of-fungal-rab11-secretory-vesicles-involves-myosin-5-dynein-dynactin-p25-and-kinesin-1-and-is-independent-of-kinesin-3
#20
Miguel A Peñalva, Jun Zhang, Xin Xiang, Areti Pantazopoulou
Hyphal tip cells of the fungus Aspergillus nidulans are useful to study long-range intracellular traffic. Post-Golgi secretory vesicles (SVs) containing the RAB11 orthologue RabE engage myosin-5 as well as plus-end- and minus-end-directed microtubule motors, providing an experimental system to investigate the interplay between microtubule and actin motors acting on the same cargo. By exploiting the fact that depolymerization of F-actin 'unleashes' SVs focused at the apex by myosin-5 to microtubule-dependent motors, we establish that the minus-end directed transport of SVs requires the dynein/dynactin supercomplex...
February 16, 2017: Molecular Biology of the Cell
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