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https://www.readbyqxmd.com/read/28537691/the-influence-of-previous-robotic-experience-in-the-initial-learning-curve-of-laparoscopic-radical-prostatectomy
#1
José Anastácio Dias, Marcos F Dall'oglio, João Roberto Colombo, Rafael F Coelho, William Carlos Nahas
INTRODUCTION: This study analyzed the impact of the experience with Robotic-Assisted Laparoscopic Prostatectomy (RALP) on the initial experience with Laparoscopic Radical Prostatectomy (LRP) by examining perioperative results and early outcomes of 110 patients. LRPs were performed by two ro-botic fellowship trained surgeons with daily practice in RALP. PATIENTS AND METHODS: 110 LRP were performed to treat aleatory selected patients. The patients were divided into 4 groups for prospective analyses...
May 23, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28531285/paratrigeminal-paraclival-precavernous-or-all-of-the-above-a-circumferential-anatomical-study-of-the-c3-c4-transitional-segment-of-the-internal-carotid-artery
#2
Eleonora Marcati, Norberto Andaluz, Sebastien C Froelich, Lee A Zimmer, James L Leach, Juan Carlos Fernandez-Miranda, Almaz Kurbanov, Jeffrey T Keller
BACKGROUND: Although the term paraclival carotid pervades recent skull base literature, no clear consensus exists regarding boundaries or anatomical segments. OBJECTIVE: To reconcile various internal carotid artery (ICA) nomenclatures for transcranial and endoscopic-endonasal perspectives, we reexamined the transition between lacerum (C3) and cavernous (C4) segments using a C1-C7 segments schema. In this cadaveric study, we obtained a 360°-circumferential view integrating histological, microsurgical, endoscopic, and neuroradiological analyses of this C3-C4 region and identified a distinct transitional segment...
May 21, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28528629/correlative-light-and-electron-microscopic-detection-of-gfp-labeled-proteins-using-modular-apex
#3
Nicholas Ariotti, Thomas E Hall, Robert G Parton
The use of green fluorescent protein (GFP) and related proteins has revolutionized light microscopy. Here we describe a rapid and simple method to localize GFP-tagged proteins in cells and in tissues by electron microscopy (EM) using a modular approach involving a small GFP-binding peptide (GBP) fused to the ascorbate peroxidase-derived APEX2 tag. We provide a method for visualizing GFP-tagged proteins by light and EM in cultured cells and in the zebrafish using modular APEX-GBP. Furthermore, we describe in detail the benefits of this technique over many of the currently available correlative light and electron microscopy approaches and demonstrate APEX-GBP is readily applicable to modern three-dimensional techniques...
2017: Methods in Cell Biology
https://www.readbyqxmd.com/read/28528162/intervendor-differences-in-the-accuracy%C3%A2-of%C3%A2-detecting-regional-functional%C3%A2-abnormalities-a-report-from-the-eacvi-ase-strain-standardization-task%C3%A2-force
#4
Oana Mirea, Efstathios D Pagourelias, Jurgen Duchenne, Jan Bogaert, James D Thomas, Luigi P Badano, Jens-Uwe Voigt
OBJECTIVES: The purpose of this study was to compare the accuracy of vendor-specific and independent strain analysis tools to detect regional myocardial function abnormality in a clinical setting. BACKGROUND: Speckle tracking echocardiography has been considered a promising tool for the quantitative assessment of regional myocardial function. However, the potential differences among speckle tracking software with regard to their accuracy in identifying regional abnormality has not been studied extensively...
May 11, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28527851/intentional-replantation-of-an-avulsed-immature-permanent-incisor-a-case-report
#5
Claudio Maniglia-Ferreira, Fabio de Almeida Gomes, Marcelo de Morais Vitoriano
This case report discusses the successful endodontic treatment of an open apex maxillary right permanent central incisor that had been avulsed and incorrectly replanted in a 7-year-old patient. The tooth was carefully re-extracted followed by cleaning of the alveolar socket and immediate replantation. However, pulp necrosis was diagnosed, and regenerative endodontic treatment was performed. The root canal system was disinfected by passive ultrasonic irrigation with 2.5% sodium hypochlorite. At the first visit, the tooth was repositioned and immobilized with an appropriate semirigid splint...
May 17, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28525920/torsade-de-pointes-arrhythmias-arise-at-the-site-of-maximal-heterogeneity-of-repolarization-in-the-chronic-complete-atrioventricular-block-dog
#6
Albert Dunnink, Thom R G Stams, Alexandre Bossu, Veronique M F Meijborg, Jet D M Beekman, Sofieke C Wijers, Jacques M T De Bakker, Marc A Vos
Aims: The chronic complete atrioventricular block (CAVB) dog is highly sensitive for drug-induced torsade de pointes (TdP) arrhythmias. Focal mechanisms have been suggested as trigger for TdP onset; however, its exact mechanism remains unclear. In this study, detailed mapping of the ventricles was performed to assess intraventricular heterogeneity of repolarization in relation to the initiation of TdP. Methods and results: In 8 CAVB animals, 56 needles, each containing 4 electrodes, were inserted in the ventricles...
May 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28525608/surgical-resection-for-advanced-lung-cancer-using-the-hemi-clamshell-approach
#7
Yasushi Shintani, Ryu Kanzaki, Tomohiro Kawamura, Soichiro Funaki, Masato Minami, Meinoshin Okumura, Eiji Okura, Yoshihisa Kadota, Mitsunori Ohta
OBJECTIVES: The hemi-clamshell (HCS) approach consists of partial sternotomy with antero-lateral thoracotomy. This study evaluated the utilities and outcomes of the HCS approach in advanced lung cancer patients. METHODS: We retrospectively investigated 45 patients who underwent surgery for advanced lung cancer via the HCS procedure between 2000 and 2014, the indications for surgery being tumour invasion extending to the aorta arch in 5, descending aorta in 9, main pulmonary artery in 5, superior vena cava in 6, right or left atrium in 4, apical thoracic dome in 7 patients and mediastinal lymphadenopathy for left-sided lung cancer in 12...
May 19, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28525478/a-radiographic-analysis-of-cervical-sagittal-alignment-in-adolescent-idiopathic-cervical-kyphosis
#8
Xiao-Long Shen, Ye Tian, Xu-Hui Zhou, Dong Ren, Peng Cao, Wen Yuan
OBJECTIVE: The aim of this study was to analyze the radiologic features of adolescent idiopathic cervical kyphosis. SUMMARY OF BACKGROUND DATA: There are few previous reports about radiographic analysis of cervical sagittal alignment of adolescent idiopathic cervical kyphosis. A new method was proposed in this article to evaluate the severity of cervical kyphosis. PATIENTS AND METHODS: A total of 41 adolescent patients with cervical kyphosis were reviewed...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28524066/a-flight-phase-terrain-following-control-strategy-for-stable-and-robust-hopping-of-a-one-legged-robot-under-large-terrain-variations
#9
Natan Shemer, Amir Degani
This work demonstrates a simple, once per step, flight-phase control method for robots running on a planar unknown rough-terrain environment. The robot used to exemplify these control strategies is the ParkourBot, a Spring-Loaded Inverted Pendulum (SLIP)-based robot. The SLIP model is widely used for the description of humans and animals running motion and has been the basis for many robots. A known control scheme for increasing robustness of the conservative, SLIP model is the Swing Leg Retraction (SLR) method...
May 19, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28523339/medial-meniscal-extrusion-a-validation-study-comparing-different-methods-of-assessment
#10
Luke D Jones, Stephen J Mellon, Neil Kruger, Andrew P Monk, Andrew J Price, David J Beard
PURPOSE: Longitudinal cohort studies of knee OA aetiology use MRI to assess meniscal extrusion within the same knee at sequential time points. A validated method of assessment is required to ensure that extrusion is measured at the same location within the knee at each time point. Absolute perpendicular extrusion from the tibial edge can be assessed using the reference standard of segmentation of the tibia and medial meniscus. This is labour intensive and unsuitable for large cohorts...
April 21, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28523153/pleural-pressure-theory-revisited-a-role-for-capillary-equilibrium
#11
Aaron R Casha, Roberto Caruana-Gauci, Alexander Manche, Marilyn Gauci, Stanley Chetcuti, Luca Bertolaccini, Marco Scarci
BACKGROUND: Theories elucidating pleural pressures should explain all observations including the equal and opposite recoil of the chest wall and lungs, the less than expected pleural hydrostatic gradient and its variation at lobar margins, why pleural pressures are negative and how pleural fluid circulation functions. METHODS: A theoretical model describing equilibrium between buoyancy, hydrostatic forces, and capillary forces is proposed. The capillary equilibrium model described depends on control of pleural fluid volume and protein content, powered by an active pleural pump...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28522761/ventricular-action-potential-adaptation-to-regular-exercise-role-of-%C3%AE-adrenergic-and-katp-channel-function
#12
Xinrui Wang, Robert H Fitts
Regular exercise-training is known to affect the action potential duration (APD) and improve heart function, but the involvement by β-adrenergic receptor (β-AR) subtypes and/or KATP channel is unknown. To address this, female and male Sprague-Dawley rats were randomly assigned to voluntary wheel running or control groups and after 6-8 weeks training anesthetized and myocytes isolated. Exercise-training significantly increased APD of apex and base myocytes at 1Hz, while decreasing the APD at 10Hz. Ca(2+) transient durations reflected the changes observed in APD, while Ca(2+) transient amplitudes were unaffected by wheel running...
May 18, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28521936/trace-element-concentrations-in-the-apex-predator-swordfish-xiphias-gladius-from-a-mediterranean-fishery-and-risk-assessment-for-consumers
#13
S Gobert, V Pasqualini, J Dijoux, P Lejeune, E D H Durieux, M Marengo
Swordfish (Xiphias gladius L., 1758) is an apex predator, highly migratory meso-pelagic fish widely distributed in the Atlantic Ocean and Mediterranean. As top predators, this fish may be the end reservoir of the bioaccumulation of trace elements in a food chain because they occupy higher trophic levels and are an important food source, causing them to be potentially hazardous to consume. This study aims to investigate the concentration of 18 trace elements of Swordfish, caught in the Mediterranean Sea and to discuss human exposure risks...
May 15, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28521351/the-endoscopic-endonasal-transmaxillary-approach-to-meckel-s-cave-through-the-inferior-orbital-fissure
#14
Xin Zhang, Halima Tabani, Ivan El-Sayed, Matthew Russell, Xuequan Feng, Arnau Benet
BACKGROUND: Surgical access to Meckel's Cave (MC) is challenging due to its deep location and surrounding important neurovascular structures. Currently existing endoscopic endonasal (EE) approaches require dissecting near the internal carotid artery (ICA) or require transposition of the pterygopalatine neurovascular bundle. OBJECTIVE: To describe a novel approach to access the anterolateral aspect of the MC using a minimally invasive EE route. METHODS: The EE transmaxillary transinferior orbital fissure approach was simulated in 10 specimens...
June 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28514687/particulate-array-of-well-ordered-hiv-clade-c-env-trimers-elicits-neutralizing-antibodies-that-display-a-unique-v2-cap-approach
#15
Paola Martinez-Murillo, Karen Tran, Javier Guenaga, Gustaf Lindgren, Monika Àdori, Yu Feng, Ganesh E Phad, Néstor Vázquez Bernat, Shridhar Bale, Jidnyasa Ingale, Viktoriya Dubrovskaya, Sijy O'Dell, Lotta Pramanik, Mats Spångberg, Martin Corcoran, Karin Loré, John R Mascola, Richard T Wyatt, Gunilla B Karlsson Hedestam
The development of soluble envelope glycoprotein (Env) mimetics displaying ordered trimeric symmetry has ushered in a new era in HIV-1 vaccination. The recently reported native, flexibly linked (NFL) design allows the generation of native-like trimers from clinical isolates at high yields and homogeneity. As the majority of infections world-wide are of the clade C subtype, we examined responses in non-human primates to well-ordered subtype C 16055 trimers administered in soluble or high-density liposomal formats...
May 16, 2017: Immunity
https://www.readbyqxmd.com/read/28514685/virus-like-particles-identify-an-hiv-v1v2-apex-binding-neutralizing-antibody-that-lacks-a-protruding-loop
#16
Evan M Cale, Jason Gorman, Nathan A Radakovich, Ema T Crooks, Keiko Osawa, Tommy Tong, Jiaqi Li, Raju Nagarajan, Gabriel Ozorowski, David R Ambrozak, Mangai Asokan, Robert T Bailer, Anthony K Bennici, Xuejun Chen, Nicole A Doria-Rose, Aliaksandr Druz, Yu Feng, M Gordon Joyce, Mark K Louder, Sijy O'Dell, Courtney Oliver, Marie Pancera, Mark Connors, Thomas J Hope, Thomas B Kepler, Richard T Wyatt, Andrew B Ward, Ivelin S Georgiev, Peter D Kwong, John R Mascola, James M Binley
Most HIV-1-specific neutralizing antibodies isolated to date exhibit unusual characteristics that complicate their elicitation. Neutralizing antibodies that target the V1V2 apex of the HIV-1 envelope (Env) trimer feature unusually long protruding loops, which enable them to penetrate the HIV-1 glycan shield. As antibodies with loops of requisite length are created through uncommon recombination events, an alternative mode of apex binding has been sought. Here, we isolated a lineage of Env apex-directed neutralizing antibodies, N90-VRC38...
May 16, 2017: Immunity
https://www.readbyqxmd.com/read/28514679/size-doesn-t-matter-shorter-antibody-loops-can-infiltrate-hiv-s-env-apex-defenses
#17
Jinal N Bhiman, Penny L Moore
An HIV vaccine that elicits broadly neutralizing antibodies, which often have unusual structural features, has not yet been developed. In Immunity this month, Cale et al., 2017 describe how a new mode of binding allows a conventional antibody to infiltrate HIV's armor.
May 16, 2017: Immunity
https://www.readbyqxmd.com/read/28514496/a-reappraisal-of-children-s-thoracic-surface-anatomy
#18
Nicholas Fischer, Jonty Morreau, Ramanen Sugunesegran, Kiarash Taghavi, Ali Mirjalili
Accurate knowledge of surface anatomy is fundamental to safe clinical practice. A paucity of evidence in the literature regarding thoracic surface anatomy in children was identified. The associations between surface landmarks and internal structures were meticulously analyzed by reviewing high quality computed tomography (CT) images of 77 children aged from four days to 12 years. The results confirmed that the sternal angle is an accurate surface landmark for the azygos-superior vena cava junction in a plane through to the level of upper T4 from birth to age four, and to lower T4 in older children...
May 17, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28514341/-endodontic-treatment-efficacy-enhancement-by-means-of-instrumental-physiotherapy
#19
I M Makeeva, A G Volkov, N Zh Dikopova, E G Talalaev
The article describes in detail and examines the prospects of such methods as electroodontodiagnosis, diathermocoagulation and apex-phoresis. It proves the necessity of development and standardization of devices for the mentioned treatment modalities that will improve the effectiveness an quality of caries complications treatment.
2017: Stomatologii︠a︡
https://www.readbyqxmd.com/read/28512495/endodontic-management-of-open-apex-teeth-using-lyophilized-collagen-sponge-and-mta-cement-report-of-two-cases
#20
Miriam Graziele Magro, Milton Carlos Kuga, Weber Adad Ricci, Kátia Cristina Keine, Mateus Rodrigues Tonetto, Suellen Linares Lima, Alvaro Henrique Borges, Lauriê Garcia Belizário, Matheus Coêlho Bandeca
Teeth with open apices, such as in immature teeth or those with apical root resorption are clinical cases with difficult immediate resolution. With the use of mineral trioxide aggregate (MTA) in dentistry, it was possible to optimize the treatment time of these cases by immediate placement of apical plug and the root canal filling. However, some negative effects can occur if MTA is extruded beyond the apex. To avoid this accident, it has been recommended to use of an apical matrix prior to placement of MTA...
2017: Iranian Endodontic Journal
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