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https://www.readbyqxmd.com/read/28430777/correction-the-subclonal-architecture-of-metastatic-breast-cancer-results-from-a-prospective-community-based-rapid-autopsy-program-cascade
#1
Peter Savas, Zhi Ling Teo, Christophe Lefevre, Christoffer Flensburg, Franco Caramia, Kathryn Alsop, Mariam Mansour, Prudence A Francis, Heather A Thorne, Maria Joao Silva, Nnennaya Kanu, Michelle Dietzen, Andrew Rowan, Maik Kschischo, Stephen Fox, David D Bowtell, Sarah-Jane Dawson, Terence P Speed, Charles Swanton, Sherene Loi
[This corrects the article DOI: 10.1371/journal.pmed.1002204.].
April 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28430705/disparities-in-female-breast-cancer-stage-at-diagnosis-in-new-jersey-a-spatial-temporal-analysis
#2
Lisa M Roche, Xiaoling Niu, Antoinette M Stroup, Kevin A Henry
BACKGROUND: Despite improvements in early detection of breast cancer, disparities persist in stage at diagnosis, which is an important prognostic factor. METHODS: We used the space-time scan statistic in SaTScan to identify geographic areas and time periods with significantly elevated proportions of female breast cancer diagnosed at the in situ or distant stage in New Jersey. The analyses were conducted with census tracts as the geographic unit of analysis, elliptical spatial windows, 3-year temporal windows, and Poisson models...
December 22, 2016: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28427084/long-term-improvement-of-breast-cancer-survivors-quality-of-life-by-a-2-week-group-physical-and-educational-intervention-5-year-update-of-the-pacthe-trial
#3
Fabrice Kwiatkowski, Marie-Ange Mouret-Reynier, Martine Duclos, François Bridon, Thierry Hanh, Isabelle Van Praagh-Doreau, Armelle Travade, Marie-Paule Vasson, Sylvie Jouvency, Christian Roques, Yves-Jean Bignon
BACKGROUND: The advantages of adapted physical activity and nutritional education (APANE) on breast cancer prognosis and quality of life (QoL) are well known, but long-term results are lacking. METHODS: A randomised controlled trial testing a 2-week intervention in hydrothermal centres including APANE enrolled 251 patients post-chemotherapy. QoL and weight control were significantly improved at 12 months. A 5-year follow-up was performed to evaluate the persistence of improvements...
April 20, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28427083/cumulative-risk-of-breast-cancer-screening-outcomes-according-to-the-presence-of-previous-benign-breast-disease-and-family-history-of-breast-cancer-supporting-personalised-screening
#4
M Román, M J Quintana, J Ferrer, M Sala, X Castells
BACKGROUND: Our aim was to assess the cumulative risk of false-positive screening results, screen-detected cancer, and interval breast cancer in mammography screening among women with and without a previous benign breast disease and a family history of breast cancer. METHODS: The cohort included 42 928 women first screened at the age of 50-51 years at three areas of the Spanish Screening Programme (Girona, and two areas in Barcelona) between 1996 and 2011, and followed up until December 2012...
April 20, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28421657/core-outcome-sets-in-women-s-and-newborn-health-a-systematic-review
#5
James M N Duffy, Rachel Rolph, Chris Gale, Martin Hirsch, Khalid S Khan, Sue Ziebland, Richard J McManus
BACKGROUND: Variation in outcome collection and reporting is a serious hindrance to progress in our specialty, over eighty journals have come together to support the development, dissemination, and implementation of core outcome sets. OBJECTIVE: This study systematically reviewed and characterised registered, progressing, or completed core outcome sets relevant to women's and newborn health. SEARCH STRATEGY: Systematic search using the Core Outcome Measures in Effectiveness Trial initiative and the Core Outcomes in Women's and Newborn Health initiative databases...
April 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28419079/predicting-breast-cancer-response-to-neoadjuvant-chemotherapy-using-pretreatment-diffuse-optical-spectroscopic-texture-analysis
#6
William T Tran, Mehrdad J Gangeh, Lakshmanan Sannachi, Lee Chin, Elyse Watkins, Silvio G Bruni, Rashin Fallah Rastegar, Belinda Curpen, Maureen Trudeau, Sonal Gandhi, Martin Yaffe, Elzbieta Slodkowska, Charmaine Childs, Ali Sadeghi-Naini, Gregory J Czarnota
BACKGROUND: Diffuse optical spectroscopy (DOS) has been demonstrated capable of monitoring response to neoadjuvant chemotherapy (NAC) in locally advanced breast cancer (LABC) patients. In this study, we evaluate texture features of pretreatment DOS functional maps for predicting LABC response to NAC. METHODS: Locally advanced breast cancer patients (n=37) underwent DOS breast imaging before starting NAC. Breast tissue parametric maps were constructed and texture analyses were performed based on grey-level co-occurrence matrices for feature extraction...
April 18, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28419078/targeting-of-ccbe1-by-mir-330-3p-in-human-breast-cancer-promotes-metastasis
#7
Aruz Mesci, Xiaoyong Huang, Samira Taeb, Sahar Jahangiri, Yohan Kim, Emmanouil Fokas, Jeff Bruce, Hon S Leong, Stanley K Liu
BACKGROUND: MicroRNAs (miRs) are involved in the regulation of many processes that contribute to malignancy, including cell proliferation, radiation resistance, invasion and metastasis. The role of miR-330-3p, an miR upregulated in breast cancer, remains unclear. METHODS: We examine the association of miR-330-3p with distant relapse-free survival in the Oxford cohort of breast cancer patients. We also study miR-330-3p function using in vitro invasion and ex ovo metastasis assays...
April 18, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28406980/correction-tensor-based-multichannel-reconstruction-for-breast-tumours-identification-from-dce-mris
#8
X-X Yin, S Hadjiloucas, J-H Chen, Y Zhang, J-L Wu, M-Y Su
[This corrects the article DOI: 10.1371/journal.pone.0172111.].
2017: PloS One
https://www.readbyqxmd.com/read/28401819/-a-plea-for-selective-use-of-the-mammaprint-test
#9
M de Boer, A C Voogd, V C G Tjan-Heijnen
Recently, the results of the MINDACT study were published in The New England Journal of Medicine. The authors conclude that the MammaPrint test can prevent the use of chemotherapy in about 50% of breast cancer patients with a high-risk clinical profile because of the presence of a genomic low risk MammaPrint. We believe that the decision to use chemotherapy should not be based solely on the outcome of the MammaPrint test, as is suggested by the authors, but also on clinical factors, such as tumour size, nodal status and grade...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28397023/effects-of-non-pharmacological-supportive-care-for-hot-flushes-in-breast-cancer-a-meta-analysis
#10
Wei-Wei Tao, Xiao-Mei Tao, Chun-Li Song
PURPOSE: To assess the efficacy of non-pharmacological therapies for hot flushes (HFs) in women with breast cancer (BC). METHODS: Nine databases (MEDLINE, Cochrane Central Register of Controlled Trials, EMBASE, PsycINFO, CINAHL, China National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database (VIP), China Biology Medicine (CBM), and Wan Fang Database) were searched from their inceptions to October 2016. We also hand-searched reference lists of reviews and included articles, reviewed conference proceedings, and contacted experts...
April 11, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28390551/review-of-the-evidence-on-the-use-of-arbitration-or-consensus-within-breast-screening-a-systematic-scoping-review
#11
REVIEW
L Hackney, A Szczepura, L Moody, B Whiteman
OBJECTIVES: A systematic scoping review was undertaken to establish the evidence base on arbitration and consensus in mammography reporting. Database searches were supplemented with hand searching of peer-reviewed journals, citation tracking, key author searching, grey literature and personal contact with experts. A 3-stage process was utilised to screen a large volume of literature (601) against the inclusion and exclusion criteria. 26 papers were retained. KEY FINDINGS: A lack of guidance and underpinning evidence to inform how best to use arbitration or consensus to resolve discordant reads...
May 2017: Radiography
https://www.readbyqxmd.com/read/28375855/cause-specific-mortality-in-a-population-based-cohort-of-9799-women-treated-for-ductal-carcinoma-in-situ
#12
Lotte E Elshof, Marjanka K Schmidt, Emiel J Th Rutgers, Flora E van Leeuwen, Jelle Wesseling, Michael Schaapveld
OBJECTIVE: To assess cause-specific mortality in women treated for ductal carcinoma in situ (DCIS). BACKGROUND: From screening and treatment perspective, it is relevant to weigh the low breast cancer mortality after DCIS against mortality from other causes and expected mortality in the general population. METHODS: We conducted a population-based cohort study comprising 9799 Dutch women treated for primary DCIS between 1989 and 2004 and estimated standardized mortality ratios (SMRs)...
April 3, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28374304/septum-enhanced-mammaplasty-in-inferocentral-pedicled-breast-reduction-for-macromastia-and-gigantomastia-patients
#13
Aurelio Portincasa, Francesco Ciancio, Luigi Cagiano, Alessandro Innocenti, Domenico Parisi
BACKGROUND: Inferior pedicle and free nipple grafting are commonly used as breast reduction techniques for patients with breast hypertrophy and gigantomastia. Limitations of these techniques are, respectively, possible vascular compromise and total/partial necrosis of the nipple-areola complex (NAC). The authors describe the innovative inferocentral pedicled reduction mammaplasty (ICPBR) enhanced by preservation of Würinger's septum for severe hypertrophic breasts. MATERIALS AND METHODS: Among 287 breast reductions performed between January 2001 and 2015, 83 (28...
April 3, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28374302/reduction-mammaplasty-for-breast-symmetrisation-in-implant-based-reconstructions
#14
Fabrizio De Biasio, Nicola Zingaretti, Francesca De Lorenzi, Michele Riccio, Luca Vaienti, Pier Camillo Parodi
BACKGROUND: Healthy breast surgery constitutes an important step to achieve symmetry in unilateral implant-based reconstructions. We analysed long-term results of breast symmetry obtained with reduction mammaplasties, and we evaluated whether different glandular pedicles may better preserve long-term stability. METHOD: Between 2006 and 2012, 90 patients underwent mastectomy and immediate reconstruction with tissue expanders and simultaneous contralateral reduction mammaplasty...
April 3, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28374300/the-impact-of-expander-inflation-deflation-status-during-adjuvant-radiotherapy-on-the-complications-of-immediate-two-stage-breast-reconstruction
#15
Kyong-Je Woo, Joo-Myeong Paik, Sa Ik Bang, Goo-Hyun Mun, Jai-Kyong Pyon
BACKGROUND: The question of whether expander inflation/deflation status has any bearing on surgical complications in the setting of adjuvant radiation (XRT) has not been addressed. The objective of this study is to investigate whether the inflation/deflation status of the expander at the time of XRT is associated with complications in immediate two-stage expander-implant breast reconstruction. METHODS: A retrospective review of 49 consecutive patients who underwent immediate two-stage expander-implant breast reconstruction and received post-mastectomy XRT was conducted...
April 3, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28374293/the-inframammary-fold-imf-a-poorly-appreciated-landmark-in-prosthetic-alloplastic-breast-aesthetic-and-reconstructive-surgery-personal-experience
#16
Bishara Atiyeh, Amir Ibrahim, Salim Saba, Raffy Karamanoukian, Fadl Chahine, Nazareth Papazian
The inframammary fold (IMF) is the most critical visual landmark that affects final aesthetic outcome of augmentation mammoplasty and even post-mastectomy alloplastic breast reconstruction. Unfortunately, structural integrity of this landmark is greatly overlooked and very often neglected. Excessive undermining of the lower breast pole with aggressive disruption/lowering and subsequent poor reconstitution of the IMF scaffold combined with imbalanced implant-tissue dynamics may result in downward implant displacement with creep bottoming and upward tilt of the nipples...
April 3, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28360432/dose-response-effects-of-aerobic-exercise-on-energy-compensation-in-postmenopausal-women-combined-results-from-two-randomized-controlled-trials
#17
J McNeil, D R Brenner, K S Courneya, C M Friedenreich
BACKGROUND/OBJECTIVE: Despite the clear health benefits of exercise, exercised-induced weight loss is often less than expected. The term 'exercise energy compensation' is used to define the amount of weight loss below what is expected for the amount of exercise energy expenditure. We examined the dose-response effects of exercise volume on energy compensation in postmenopausal women. PARTICIPANTS/METHODS: Data from Alberta Physical Activity and Breast Cancer Prevention (ALPHA) and Breast Cancer and Exercise Trial in Alberta (BETA) were combined for the present analysis...
March 31, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28359079/evaluating-wait-times-from-screening-to-breast-cancer-diagnosis-among-women-undergoing-organised-assessment-vs-usual-care
#18
Anna M Chiarelli, Derek Muradali, Kristina M Blackmore, Courtney R Smith, Lucia Mirea, Vicky Majpruz, Frances P O'Malley, May Lynn Quan, Claire Mb Holloway
BACKGROUND: Timely coordinated diagnostic assessment following an abnormal screening mammogram reduces patient anxiety and may optimise breast cancer prognosis. Since 1998, the Ontario Breast Screening Program (OBSP) has offered organised assessment through Breast Assessment Centres (BACs). For OBSP women seen at a BAC, an abnormal mammogram is followed by coordinated referrals through the use of navigators for further imaging, biopsy, and surgical consultation as indicated. For OBSP women seen through usual care (UC), further diagnostic imaging is arranged directly from the screening centre and/or through their physician; results must be communicated to the physician who is then responsible for arranging any necessary biopsy and/or surgical consultation...
March 30, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28359077/sleep-and-survival-among-women-with-breast-cancer-30-years-of-follow-up-within-the-nurses-health-study
#19
Claudia Trudel-Fitzgerald, Eric S Zhou, Elizabeth M Poole, Xuehong Zhang, Karin B Michels, A Heather Eliassen, Wendy Y Chen, Michelle D Holmes, Shelley S Tworoger, Eva S Schernhammer
BACKGROUND: Breast cancer is a leading cause of cancer death in women. Sleep has been linked with mortality among cancer-free population; however, its association with survival among women with breast cancer is understudied. METHODS: Breast cancer patients (N=3682) reported their average sleep duration post diagnosis. Subsamples also provided their pre-diagnosis sleep duration (n=1949) and post-diagnosis sleep difficulties (n=1353). Multivariate Cox models estimated hazard ratios (HR) and confidence intervals (CI) of all-cause, breast cancer, and non-breast cancer mortality...
March 30, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28350789/dependence-of-cancer-risk-from-environmental-exposures-on-underlying-genetic-susceptibility-an-illustration-with-polycyclic-aromatic-hydrocarbons-and-breast-cancer
#20
Jing Shen, Yuyan Liao, John L Hopper, Mandy Goldberg, Regina M Santella, Mary Beth Terry
BACKGROUND: Most studies of environmental risk factors and breast cancer are conducted using average risk cohorts. METHODS: We examined the association between polycyclic aromatic hydrocarbon (PAH)-albumin adducts in bloods from baseline and breast cancer risk in a prospective nested case-control study (New York site of the BCFR, 80 cases and 156 controls). We estimated the 10-year absolute breast cancer risk by a risk model that uses pedigree information (BOADICEA) and evaluated whether the increased risk from PAH differed by absolute risk...
March 28, 2017: British Journal of Cancer
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