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tos ferina

Sandra Beltrán Silva, Yolanda Cervantes Apolinar, James D Cherry, Carlos Conde González, Angela Gentile, César Misael Gómez Altamirano, Marte Hernández Porras, Gloria Huerta García, Mercedes Macías Parra, Gerardo Martínez Aguilar, Abiel Mascareñas de los Santos, Sarbelio Moreno Espinosa, Aarón Pacheco Ríos, David Prado Cohrs, Miguel Angel Rodriguez Weber, Luis Romano Mazzotti, Erick Rosales Uribe, José Sifuentes Osornio, Rolando Ulloa-Gutiérrez, Alberto Villaseñor Sierra
Pertussis continues to be responsible for a significant disease burden worldwide. Although immunization practices have reduced the occurrence of the disease among children, waning vaccine- and infection-induced immunity still allows the disease to affect adolescents and adults who, in turn, can transmit the disease to non-immunized or partially immunized infants. This document is the result of a meeting in Mexico City of international experts who analyzed recent medical information in order to establish the current status of the epidemiology, diagnosis and surveillance of pertussis and, especially, the value of the dTpa booster dose in adolescents and adults as a pertussis prevention strategy in Mexico...
January 2011: Salud Pública de México
Juan Carlos Sanz Moreno, Fernando De Ory Manchón, Julia González Alonso, José Luis de La Torre, Francisco Salmerón, Aurora Limia, Odorina Tello, Isabel Pachón, Carmen Amela, Julio Vázquez, Fernando de Ory, Juan Carlos Sanz
Culture is the reference method for the diagnosis of infection by Bordetella pertussis. Nevertheless, delayed sample collection and previous antibiotic treatment can limit culture sensitivity. In principle, direct immunofluorescence provides immediate diagnosis. It is, however, a subjective procedure that shows low sensitivity and specificity. PCR techniques increase culture sensitivity while maintaining high specificity, but their performance decreases along the evolution of the disease. Serologic methods are the main alternative for cases in which diagnosis is delayed...
May 2002: Enfermedades Infecciosas y Microbiología Clínica
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