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Michela Barbaro, Annika Ohlsson, Stephan Borte, Susanne Jonsson, Rolf H Zetterström, Jovanka King, Jacek Winiarski, Ulrika von Döbeln, Lennart Hammarström
Newborn screening for severe primary immunodeficiencies (PID), characterized by T and/or B cell lymphopenia, was carried out in a pilot program in the Stockholm County, Sweden, over a 2-year period, encompassing 58,834 children. T cell receptor excision circles (TREC) and kappa-deleting recombination excision circles (KREC) were measured simultaneously using a quantitative PCR-based method on DNA extracted from dried blood spots (DBS), with beta-actin serving as a quality control for DNA quantity. Diagnostic cutoff levels enabling identification of newborns with milder and reversible T and/or B cell lymphopenia were also evaluated...
November 21, 2016: Journal of Clinical Immunology
Adam Drewnowski, Anju Aggarwal, Wesley Tang, Philip M Hurvitz, Jason Scully, Orion Stewart, Anne Vernez Moudon
BACKGROUND: The built environment (BE) is said to influence local obesity rates. Few studies have explored causal pathways between home-neighborhood BE variables and health outcomes such as obesity. Such pathways are likely to involve both physical activity and diet. METHODS: The Seattle Obesity Study (SOS II) was a longitudinal cohort of 440 adult residents of King Co, WA. Home addresses were geocoded. Home-neighborhood BE measures were framed as counts and densities of food sources and physical activity locations...
November 10, 2016: BMC Public Health
P Grady Dixon, Adam J Kalkstein
There has been much research on the associations between weather variables and suicide rates. However, the state of understanding has remained rather stagnant due to many contradictory findings. The purpose of this project is to examine a larger database of suicides that includes a longer and more recent period of record (1975-2010) across numerous locations in the USA. In all, we examine nine total counties (and the primary city associated with them) with a special effort made to compare locations with varying degrees of temperature seasonality: Cook (Chicago), Fulton (Atlanta), King (Seattle), Los Angeles (Los Angeles), Maricopa (Phoenix), Miami-Dade (Miami), Philadelphia (Philadelphia), Salt Lake (Salt Lake City), and St...
November 7, 2016: International Journal of Biometeorology
Milan S Geybels, Karen D McCloskey, Ian G Mills, Janet L Stanford
BACKGROUND: Calcium channel blockers (CCBs) may affect prostate cancer (PCa) growth by various mechanisms including those related to androgens. The fusion of the androgen-regulated gene TMPRSS2 and the oncogene ERG (TMPRSS2:ERG or T2E) is common in PCa, and prostate tumors that harbor the gene fusion are believed to represent a distinct disease subtype. We studied the association of CCB use with the risk of PCa, and molecular subtypes of PCa defined by T2E status. METHODS: Participants were residents of King County, Washington, recruited for population-based case-control studies (1993-1996 or 2002-2005)...
October 18, 2016: Prostate
Michael Todd, Marc A Adams, Jonathan Kurka, Terry L Conway, Kelli L Cain, Matthew P Buman, Lawrence D Frank, James F Sallis, Abby C King
An infrequently studied question is how diverse combinations of built environment (BE) features relate to physical activity (PA) for older adults. We derived patterns of geographic information systems- (GIS) measured BE features and explored how they accounted for differences in objective and self-reported PA, sedentary time, and BMI in a sample of older adults. Senior Neighborhood Quality of Life Study participants (N=714, aged 66-97years, 52.1% women, 29.7% racial/ethnic minority) were sampled in 2005-2008 from the Seattle-King County, WA and Baltimore, MD-Washington, DC regions...
December 2016: Preventive Medicine
Patricia Jabre, Wulfran Bougouin, Florence Dumas, Pierre Carli, Corinne Antoine, Laurent Jacob, Benjamin Dahan, Frankie Beganton, Jean-Philippe Empana, Eloi Marijon, Nicole Karam, Alexandre Loupy, Carmen Lefaucheur, Daniel Jost, Alain Cariou, Frédéric Adnet, Thomas D Rea, Xavier Jouven
Background: In patients with out-of-hospital cardiac arrest (OHCA), care requirements can conflict with the need to promptly focus efforts on organ donation in patients who are pronounced dead. Objective: To evaluate objective criteria for identifying patients with OHCA with no chance of survival during the first minutes of cardiopulmonary resuscitation to enable prompt orientation toward organ donation. Design: Retrospective assessment using OHCA data from 2 registries and 1 trial...
September 13, 2016: Annals of Internal Medicine
Simone Stoute, Richard Chin, Beate Crossley, C Gabriel Sentíes-Cué, Arthur Bickford, Mary Pantin-Jackwood, Richard Breitmeyer, Annette Jones, Silvia Carnaccini, H L Shivaprasad
In January 2015, a highly pathogenic Eurasian lineage H5N8 avian influenza (AI) virus (AIV) was detected in a commercial meat turkey flock in Stanislaus County, CA. Approximately 3 wk later, a similar case was diagnosed in commercial brown layers from a different company located in Kings County, CA. Five 14-wk-old turkey hens were submitted to the California Animal Health and Food Safety Laboratory System (CAHFS), Turlock, and eleven 12-wk-old chickens were submitted to CAHFS, Tulare laboratory due to an acute increase in flock mortality...
September 2016: Avian Diseases
Raymond J King, Nedra Garrett, Jeffrey Kriseman, Melvin Crum, Edward M Rafalski, David Sweat, Renee Frazier, Sue Schearer, Teresa Cutts
We present a framework for developing a community health record to bring stakeholders, information, and technology together to collectively improve the health of a community. It is both social and technical in nature and presents an iterative and participatory process for achieving multisector collaboration and information sharing. It proposes a methodology and infrastructure for bringing multisector stakeholders and their information together to inform, target, monitor, and evaluate community health initiatives...
September 8, 2016: Preventing Chronic Disease
Laurie Sylla, René Franzen, Debra Srebnik, Marla Hoffman, Amnon Shoenfeld
Demand for supportive housing outstrips availability in metropolitan regions around the country. Individuals who are homeless with serious mental illnesses, substance abuse, and other debilitating health conditions are often heavy users of publicly financed services and institutions, such as jails, emergency departments, psychiatric and medical hospitals, and sobering and detoxification services. King County, in collaboration with community partners, has developed a regional system for coordinating and prioritizing access to this limited resource based on utilization of publicly financed services/institutions and/or vulnerability...
August 11, 2016: Journal of Behavioral Health Services & Research
Vance Kawakami, Krista Rietberg, Beth Lipton, Kaye Eckmann, Maryann Watkins, Hanna Oltean, Meagan Kay, Chantal Rothschild, Miwako Kobayashi, Chris Van Beneden, Jeff Duchin
On March 17, 2016, Public Health-Seattle & King County in Washington was notified of two persons who received a diagnosis of Streptococcus equi subspecies zooepidemicus (S. zooepidemicus) infections. S. zooepidemicus is a zoonotic pathogen that rarely causes human illness and is usually associated with consuming unpasteurized dairy products or with direct horse contact (1). In horses, S. zooepidemicus is a commensal bacterium that can cause respiratory, wound, and uterine infections (2). The health department investigated to determine the magnitude of the outbreak, identify risk factors, and offer recommendations...
2016: MMWR. Morbidity and Mortality Weekly Report
Junfeng Jiao, Adam Drewnowski, Anne Vernez Moudon, Anju Aggarwal, Jean-Michel Oppert, Helene Charreire, Basile Chaix
This study analyzed the impact of area residential property values, an objective measure of socioeconomic status (SES), on self-rated health (SRH) in Seattle, Washington and Paris, France. This study brings forth a valuable comparison of SRH between cities that have contrasting urban forms, population compositions, residential segregation, food systems and transportation modes. The SOS (Seattle Obesity Study) was based on a representative sample of 1394 adult residents of Seattle and King County in the United States...
December 2016: Preventive Medicine Reports
Roxanne P Kerani, Joshua T Herbeck, Susan E Buskin, Julia C Dombrowksi, Amy Bennett, Elizabeth Barash, Lindley A Barbee, Matthew R Golden
Little is known about the frequency of ongoing HIV transmission within U.S. African immigrant communities. We used HIV surveillance and partner services data to describe African-born persons newly reported with HIV infection in King County (KC), WA from 1/1/2010 to 12/31/2013. We performed phylogenetic clustering analysis of HIV-1 pol to identify putative transmission events within this population. From 2010 to 2013, 1148 KC adults were reported with HIV, including 102 (9 %) born in Africa. Forty-one African-born cases were interviewed and reported diagnosis after arrival in the U...
July 9, 2016: Journal of Immigrant and Minority Health
(no author information available yet)
In the report, "Declines in Student Obesity Prevalence Associated with a Prevention Initiative - King County, Washington, 2012," the following errors occurred.
2016: MMWR. Morbidity and Mortality Weekly Report
Philippa Anderson, Julian King, Michelle Moss, Phil Light, Tracy McKee, Elizabeth Farrell, Joanna Stewart, Diana Lennon
AIM: To evaluate registered nurse-led school clinics in 61 primary and intermediate schools in Counties Manukau. METHODS: The evaluation (conducted August–December, 2014) collated evidence concerning service delivery, outcomes, value for money and effectiveness. RESULTS: 97% (23,756/24,497) of eligible children were consented, 11% (20,696/191,423) of throat swabs taken (February 2013–September 2014) were culture positive for Group A Streptococcus (GAS); 20,176 were treated...
January 8, 2016: New Zealand Medical Journal
Sean K Sayers, Marisa E Domino, Gary S Cuddeback, Nadine J Barrett, Joseph P Morrissey
Large urban jails have become a collection point for many persons with severe mental illness. Connections between jail and community mental health services are needed to assure in-jail care and to promote successful community living following release. This paper addresses this issue for 2855 individuals with severe mental illness who received community mental health services prior to jail detention in King County (Seattle), Washington over a 5-year time period using a unique linked administrative data source...
June 24, 2016: Psychiatric Quarterly
Ching-Fen Chang, Chwan-Chuen King, Cho-Hua Wan, Yun-Cheng Chang, Ta-Chien Chan, Chang-Chun David Lee, Po-Hao Borris Chou, Zheng-Rong Tiger Li, Yao-Tsun Li, Tzu-Jung Tseng, Pei-Fen Lee, Chuan-Hsiung Chang
The largest epidemic of avian influenza (AI) in history attacked poultry and wild birds throughout Taiwan starting January 6, 2015. This study analyzed surveillance results, epidemiologic characteristics, and viral sequences by using government-released information, with the intention to provide recommendations to minimize future pandemic influenza. The H5 clade highly pathogenic AI viruses (HPAIVs) had not been detected in Taiwan before 2015. During this epidemic, four types of etiologic agents were identified: the three novel subtypes H5N2, H5N8, and H5N3 clade 2...
May 2016: Avian Diseases
Chung-Il Wi, Joshua Gauger, Maria Bachman, Jennifer Rand-Weaver, Elizabeth Krusemark, Euijung Ryu, Katherine S King, Slavica K Katusic, Young J Juhn
PURPOSE: We aimed to assess whether smoking status among individuals in late adolescence (19-22 years) with asthma was associated with socioeconomic status (SES) defined by HOUSES, an individual-housing-based SES measure. METHODS: A population-based cross-sectional study was conducted among the 1988-1989 Olmsted County, Minnesota Birth Cohort, with physician-diagnosed asthma and that lived in the community during the study period (November 1, 2008-October 31, 2012)...
July 2016: Annals of Epidemiology
(no author information available yet)
No abstract text is available yet for this article.
June 19, 2016: AIDS
Guanyang Zou, Xiaolin Wei, Joseph P Hicks, Yanhong Hu, John Walley, Jun Zeng, Helen Elsey, Rebecca King, Zhitong Zhang, Simin Deng, Yuanyuan Huang, Claire Blacklock, Jia Yin, Qiang Sun, Mei Lin
INTRODUCTION: Irrational use of antibiotics is a serious issue within China and internationally. In 2012, the Chinese Ministry of Health issued a regulation for antibiotic prescriptions limiting them to <20% of all prescriptions for outpatients, but no operational details have been issued regarding policy implementation. This study aims to test the effectiveness of a multidimensional intervention designed to reduce the use of antibiotics among children (aged 2-14 years old) with acute upper respiratory infections in rural primary care settings in China, through changing doctors' prescribing behaviours and educating parents/caregivers...
2016: BMJ Open
Scott M Carlson, Julie Kim, David A Khan, Kevin King, Richard T Lucarelli, Roderick McColl, Ronald Peshock, E Sherwood Brown
INTRODUCTION: Asthma is associated with an increased risk of mild cognitive impairment and dementia. Depression and oral corticosteroid use are associated with atrophy of the hippocampus and are common in asthma. However, minimal neuroimaging data are available in asthma patients. METHODS: We conducted a retrospective analysis of 1,287 adult participants from the Dallas Heart Study, an epidemiological sample of Dallas County residents. Study outcome variables were hippocampal volumes measured by FreeSurfer...
May 17, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
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