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https://www.readbyqxmd.com/read/28912734/malm%C3%A3-treatment-referral-and-intervention-study-high-12-month-retention-rates-in-patients-referred-from-syringe-exchange-to-methadone-or-buprenorphine-naloxone-treatment
#1
Martin Bråbäck, Lars Ekström, Katja Troberg, Suzan Nilsson, Pernilla Isendahl, Louise Brådvik, Anders Håkansson
BACKGROUND: Heroin dependence is associated with high mortality. Opioid agonist treatment (OAT) with methadone or buprenorphine has strong evidence for treatment of this relapsing condition. In our setting, OAT has been associated with strict and demanding intake procedures, often with requirements of social stability, but also high, approximately 80 percent 12-month retention rates. In a recent randomized controlled trial, we demonstrated high rates of successful rapid referral from a syringe exchange programme (SEP) to treatment with methadone or buprenorphine, including actual treatment initiation...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28882143/characteristics-of-persons-who-inject-drugs-and-who-witness-opioid-overdoses-in-vietnam-a-cross-sectional-analysis-to-inform-future-overdose-prevention-programs
#2
N A Blackburn, K E Lancaster, T V Ha, C A Latkin, W C Miller, C Frangakis, V A Chu, T Sripaipan, V M Quan, N L Minh, P T Vu, V F Go
BACKGROUND: Persons who use opioids have a high risk of overdose and associated mortality. In Vietnam, little is known about the characteristics of this population and the persons who are witness to those overdoses. One approach to combatting fatal overdose has been the use of peer interventions in which a friend or injecting partner administers overdose reversal medication, but availability in Vietnam of these medications is limited to pilot programs with aims to expand in the future (Le Minh and V...
September 7, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28879174/mobile-technology-to-increase-hiv-hcv-testing-and-overdose-prevention-response-among-people-who-inject-drugs
#3
Ian David Aronson, Alexander Bennett, Lisa A Marsch, Theodore C Bania
The United States faces dramatically increasing rates of opioid overdose deaths, as well as persistent ongoing problems of undiagnosed HIV and HCV infection. These problems commonly occur together in substance using populations that have limited, if any, access to primary care and other routine health services. To collectively address all three issues, we developed the Mobile Intervention Kit (MIK), a tablet computer-based intervention designed to provide overdose prevention and response training and to facilitate HIV/HCV testing in community settings...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28819049/a-comparison-of-protein-stability-in-prefillable-syringes-made-of-glass-and-plastic
#4
Lloyd Waxman, Vinod D Vilivalam
The development of protein therapeutics requires stabilization of these labile molecules during shipment and storage. Biologics, particularly monoclonal antibodies, are frequently packaged at high concentration in prefillable syringes traditionally made of glass. However, some biologics are unstable in glass due to sensitivity to silicone oil, tungsten, glue or metal ions. Syringes made from the plastic cyclic olefin polymer, Daikyo Crystal Zenith® (CZ), with a Flurotec-laminated piston have none of these issues...
August 17, 2017: PDA Journal of Pharmaceutical Science and Technology
https://www.readbyqxmd.com/read/28772172/naloxone-use-among-overdose-prevention-trainees-in-new-york-city-a-longitudinal-cohort-study
#5
Anne Siegler, Zina Huxley-Reicher, Lara Maldjian, Robyn Jordan, Chloe Oliver, Andrea Jakubowski, Hillary V Kunins
BACKGROUND: Providing naloxone to laypersons who are likely to witness an opioid overdose is now a widespread public health response to the national opioid overdose epidemic. Estimating the proportion of individuals who use naloxone can define its potential impact to reduce overdose deaths at a population level. We determined the proportion of study participants who used naloxone within 12 months following training and factors associated with witnessing overdose and naloxone use. METHODS: We conducted a prospective, observational study of individuals completing overdose prevention training (OPT) between June and September 2013...
July 24, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28662716/awareness-of-pre-exposure-prophylaxis-prep-among-women-who-inject-drugs-in-nyc-the-importance-of-networks-and-syringe-exchange-programs-for-hiv-prevention
#6
Suzan M Walters, Kathleen H Reilly, Alan Neaigus, Sarah Braunstein
BACKGROUND: Women who inject drugs (WWID) are at heightened risk for HIV due to biological, behavioral, and structural factors. Pre-exposure prophylaxis (PrEP) could aid in HIV prevention for WWID. However, little is known about WWID awareness of PrEP, which is a necessary step that must occur before PrEP uptake. We report factors associated with greater awareness among WWID to identify efficient means of awareness dissemination. METHODS: Data from the 2015 National HIV Behavioral Surveillance (NHBS) system cycle on injection drug use collected in New York City (NYC) were used...
June 29, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28644276/an-innovative-syringe-exchange-program
#7
Carol Potera
Nevada's pilot vending machine program encourages users to enter treatment programs.
July 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28604435/exchange-sex-and-hiv-infection-among-women-who-inject-drugs-20-us-cities-2009
#8
Lina M Nerlander, Kristen L Hess, Charles E Rose, Catlainn Sionean, Anna Thorson, Dita Broz, Gabriela Paz-Bailey
BACKGROUND: Women who inject drugs and who also exchange sex are at increased risk for HIV infection, but data on this population in the United States remain sparse. METHODS: This study assessed the prevalence of exchanging sex for money or drugs among women who inject drugs using data from the 2009 US National HIV Behavioral Surveillance (NHBS) system. Prevalence of being HIV-positive (testing positive in NHBS), HIV-positive-unaware (reporting being HIV-negative or unknown status but testing positive in NHBS), and risk behaviors and use of services were compared between women who did and did not exchange sex...
July 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28604434/trends-in-hiv-and-hcv-risk-behaviors-and-prevalent-infection-among-people-who-inject-drugs-in-new-york-city-2005-2012
#9
Alan Neaigus, Kathleen H Reilly, Samuel M Jenness, Holly Hagan, Travis Wendel, Camila Gelpi-Acosta, David M Marshall
BACKGROUND: We assess trends in HIV and hepatitis C virus (HCV) risk behaviors and prevalent infection among people who inject drugs (PWID) in New York City (NYC). METHODS: PWID in NYC were sampled using respondent-driven sampling in 2005, 2009, and 2012 (serial cross sections) for the Centers for Disease Control and Prevention-sponsored National HIV Behavioral Surveillance study. Participants were interviewed about their current (≤12 months) risk behaviors and tested for HIV and HCV...
July 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28574295/prevalence-of-hepatitis-c-and-pre-testing-awareness-of-hepatitis-c-status-in-1500-consecutive-pwid-participants-at-the-stockholm-needle-exchange-program
#10
Martin Kåberg, Anders Hammarberg, Christer Lidman, Ola Weiland
BACKGROUND: People who inject drugs (PWID) are the driving force of the hepatitis C virus (HCV) epidemic. Still, treatment is scarcely offered and the awareness of HCV status in PWID is poor. Prevention includes clean needles, syringes and other paraphernalia. HCV awareness was investigated in 1500 PWID in a needle exchange program (NEP) in Stockholm, Sweden, together with HCV prevalence, and time to HCV infection after start of injection drug use. METHODS: 1500 PWID in the Stockholm NEP were consecutively enrolled...
June 2, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28557553/decreased-odds-of-injection-risk-behavior-associated-with-direct-versus-indirect-use-of-syringe-exchange-evidence-from-two-california-cities
#11
Czarina N Behrends, Chin-Shang Li, David R Gibson
BACKGROUND: While there is substantial evidence that syringe exchange programs (SEPs) are effective in preventing HIV among people who inject drugs (PWID), nearly all the evidence comes from PWID who obtain syringes from an SEP directly. Much less is known about the benefits of secondary exchange to PWID who get syringes indirectly from friends or acquaintances who visit an SEP for them. OBJECTIVES: We evaluated the effectiveness of direct versus indirect syringe exchange in reducing HIV-related high-risk injecting behavior among PWID in two separate studies conducted in Sacramento and San Jose, California, cities with quite different syringe exchange models...
July 29, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28521814/access-to-healthcare-insurance-and-healthcare-services-among-syringe-exchange-program-clients-in-massachusetts-qualitative-findings-from-health-navigators-with-the-idu-i-do-care-collaborative
#12
Thomas J Stopka, Marguerite Hutcheson, Ashley Donahue
BACKGROUND: Little is known about access to health insurance among people who inject drugs (PWID) who attend syringe exchange programs (SEPs). The goal of the current study was to assess perceptions of SEP staff, including health navigators and program managers, on access to health insurance and healthcare access among SEP clients following implementation of state and federal policies to enhance universal healthcare access in Massachusetts. METHODS: Between December 2014 and January 2015, we conducted in-depth interviews (n = 14) with SEP staff, including both program managers and health navigators, to assess knowledge, attitudes, and beliefs related to health insurance enrollment and access to enhanced referrals among SEP clients...
May 18, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28501268/techniques-to-form-a-suitable-lipiodol-epirubicin-emulsion-by-using-3-way-stopcock-methods-in-transarterial-chemoembolization-for-liver-tumor
#13
Tetsuya Masada, Toshihiro Tanaka, Hideyuki Nishiofuku, Yasushi Fukuoka, Takeshi Sato, Shota Tatsumoto, Nagaaki Marugami, Kimihiko Kichikawa
PURPOSE: To compare physicochemical properties of emulsions of ethiodized oil (Lipiodol; Guerbet, Villepinte, France) and epirubicin prepared using different techniques for conventional transarterial chemoembolization. MATERIALS AND METHODS: Lipiodol was mixed with epirubicin solution (8.33 mg/mL) by using a 3-way stopcock. The following technical parameters were compared: ratio of epirubicin solution to Lipiodol (1:2 vs 1:1), number of pumping exchanges through the stopcock (20 exchanges vs 10 exchanges), pumping speed (1 s/push vs 2 s/push), and first push syringe (epirubicin solution vs Lipiodol)...
May 11, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28488087/comparison-of-three-popular-methods-for-recruiting-young-persons-who-inject-drugs-for-interventional-studies
#14
Melissa G Collier, Richard S Garfein, Jazmine Cuevas-Mota, Eyasu H Teshale
Persons who inject drugs (PWID) are at risk for adverse health outcomes as a result of their drug use, and the resulting social stigma makes this a difficult population to reach for interventions aimed at reducing morbidity and mortality. During our study of adult PWID aged ≤40 years living in San Diego during 2009 and 2010, we compared three different sampling methods: respondent-driven sampling (RDS), venue-based sampling at one syringe exchange program (SEP), and street-based outreach. We compared demographic, socioeconomic, health, and behavioral factors and tested participants for HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV) and compared across the three methods...
August 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28365913/a-systematic-review-and-meta-analysis-of-psychosocial-interventions-to-reduce-drug-and-sexual-blood-borne-virus-risk-behaviours-among-people-who-inject-drugs
#15
REVIEW
Gail Gilchrist, Davina Swan, Kideshini Widyaratna, Julia Elena Marquez-Arrico, Elizabeth Hughes, Noreen Dadirai Mdege, Marrissa Martyn-St James, Judit Tirado-Munoz
Opiate substitution treatment and needle exchanges have reduced blood borne virus (BBV) transmission among people who inject drugs (PWID). Psychosocial interventions could further prevent BBV. A systematic review and meta-analysis examined whether psychosocial interventions (e.g. CBT, skills training) compared to control interventions reduced BBV risk behaviours among PWID. 32 and 24 randomized control trials (2000-May 2015 in MEDLINE, PsycINFO, CINAHL, Cochrane Collaboration and Clinical trials, with an update in MEDLINE to December 2016) were included in the review and meta-analysis respectively...
July 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28328019/dopant-assisted-direct-analysis-in-real-time-mass-spectrometry-with-argon-gas
#16
Robert B Cody, A John Dane
RATIONALE: Dopants used with Atmospheric Pressure Photoionization (APPI) were examined with the Direct Analysis in Real Time (DART(®) ) ion source operated with argon gas. Charge-exchange and proton transfer reactions were observed by adding toluene, anisole, chlorobenzene and acetone to the DART gas stream, complementing the information obtained by helium DART. METHODS: Mass spectra were acquired with a time-of-flight mass spectrometer equipped with a DART ion source operated with argon gas...
May 30, 2016: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28306386/perceived-discrimination-among-racial-and-ethnic-minority-drug-users-and-the-association-with-health-care-utilization
#17
Courtney McKnight, Martha Shumway, Carmen L Masson, Enrique R Pouget, Ashly E Jordan, Don C Des Jarlais, James L Sorensen, David C Perlman
People who use drugs (PWUDs) are at increased risk for several medical conditions, yet they delay seeking medical care and utilize emergency departments (EDs) as their primary source of care. Limited research regarding perceived discrimination and PWUDs' use of health care services exists. This study explores the association between interpersonal and institutional racial/ethnic and drug use discrimination in health care settings and health care utilization among respondents (N = 192) recruited from methadone maintenance treatment programs (36%), HIV primary care clinics (35%), and syringe exchange programs (29%) in New York City (n = 88) and San Francisco (n = 104)...
March 17, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/28303199/hiv-aids-in-the-south-east-asia-region-progress-and-challenges
#18
EDITORIAL
Razia Pendse, Somya Gupta, Dongbao Yu, Swarup Sarkar
The South-East Asia region, with 11 member states, has an estimated 3.5 million people living with HIV (PLHIV). More than 99% of PLHIV live in five countries where HIV prevalence among the population aged 15-49 remains low but is between 2% and 29% among key populations. Since 2010, the region has made progress to combat the epidemic. Mature condom programmes exist in most countries but opioid substitution therapy, and needle and syringe exchange programmes need to be scaled up. HIV testing is recommended nationwide in four countries and is prioritised in high prevalence areas or for key populations in the rest...
November 28, 2016: Journal of Virus Eradication
https://www.readbyqxmd.com/read/28160735/differential-access-to-syringe-exchange-and-other-prevention-activities-among-people-who-inject-drugs-in-rural-and-urban-areas-of-puerto-rico
#19
Melissa Welch-Lazoritz, Patrick Habecker, Kirk Dombrowski, Angelica Rivera Villegas, Carmen Ana Davila, Yadira Rolón Colón, Sandra Miranda De León
BACKGROUND: Injection drug use and its associated blood-borne infections has become a rapidly increasing problem in rural areas of the US recently. Syringe exchange programs have been shown to be effective for reducing transmission of blood borne infections, however access to these prevention efforts may be limited in rural areas. METHODS: This paper utilizes two separate community samples of people who inject drugs (PWID) in Puerto Rico to achieve the following research objectives: (1) compare rural and urban access to syringe exchange programs, free sterile syringes and other HIV/HCV prevention activities, and (2) examine whether utilization of prevention activities is associated with lower injection risk behaviors...
May 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28130629/pence-putin-mbeki-and-their-hiv-aids-related-crimes-against-humanity-call-for-social-justice-and-behavioral-science-advocacy
#20
EDITORIAL
Seth C Kalichman
Indiana, a large rural state in the Midwestern United States, suffered the worst North American HIV outbreak among injection drug users in years. The Indiana state government under former Governor and current US Vice President Mike Pence fueled the HIV outbreak by prohibiting needle/syringe exchange and failed to take substantive action once the outbreak was identified. This failure in public health policy parallels the HIV epidemics driven by oppressive drug laws in current day Russia and is reminiscent of the anti-science AIDS denialism of 1999-2007 South Africa...
January 27, 2017: AIDS and Behavior
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