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https://www.readbyqxmd.com/read/29166410/devario-in-bangladesh-species-diversity-sibling-species-and-introgression-within-danionin-cyprinids-teleostei-cyprinidae-danioninae
#1
Sven O Kullander, Md Mizanur Rahman, Michael Norén, Abdur Rob Mollah
Four species of Devario are recorded from Bangladesh: D. aequipinnatus, D. anomalus, D. coxi, new species, and D. devario. Devario aequipinnatus has a wide distribution in northern India and Bangladesh. Devario coxi, from southeastern Bangladesh near Cox's Bazar, differs from D. aequipinnatus in mtDNA (COI, p-distance 1.8%), colouration, proportional measurements, and meristics. The minor morphological differences and low frequency of overlapping meristics suggest relatively recent separation of D. coxi from other D...
2017: PloS One
https://www.readbyqxmd.com/read/29165590/miltefosine-resistant-leishmania-infantum-strains-with-an-impaired-mt-ros3-transporter-complex-retain-amphotericin-b-susceptibility
#2
Annelies Mondelaers, Sarah Hendrickx, Lieselotte Van Bockstal, Louis Maes, Guy Caljon
Objectives: Increasing numbers of miltefosine treatment failures in visceral leishmaniasis therapy and reports of miltefosine resistance in the Indian subcontinent resulted in the recommendation to use liposomal amphotericin B as first-line therapy. Cross-resistance between miltefosine and amphotericin B has recently been documented, suggesting a role of mutations in the miltefosine transporter, a complex encoded by the MT and ROS3 genes. This study aimed to further explore the putative role of MT/ROS3 defects in the molecular basis of amphotericin B cross-resistance...
November 18, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29163486/structure-and-diversity-of-the-rhesus-macaque-immunoglobulin-loci-through-multiple-de-novo-genome-assemblies
#3
Akshaya Ramesh, Sam Darko, Axin Hua, Glenn Overman, Amy Ransier, Joseph R Francica, Ashley Trama, Georgia D Tomaras, Barton F Haynes, Daniel C Douek, Thomas B Kepler
The rhesus macaque is a critically important animal model in biomedical research, most recently playing a key role in the development of vaccines against human immunodeficiency virus-1. Nevertheless, the immunoglobulin (Ig) loci of macaques are as yet incompletely determined and our understanding of differences between human and macaque humoral immunity remains deficient. We completed a high-coverage, high-quality whole genome sequencing and assembly project with a single rhesus macaque of Indian origin, and partial genome assemblies using genomic molecular targeting of the Ig loci in nine other rhesus macaques of Indian origin...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29162951/down-syndrome-screening-in-india-are-we-there-yet
#4
REVIEW
K Manikandan, Suresh Seshadri
Down syndrome is the most common cause of intellectual disability among live born children and is amenable to prenatal detection. Screening for Down syndrome on a population basis requires a thorough understanding of the principles involved in the screening tests. We discuss the rationale behind the commonly available screening tests and the Indian scenario in this setting.
December 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29162886/association-of-human-leukocyte-antigen-class-1-genes-with-stevens-johnson-syndrome-with-severe-ocular-complications-in-an-indian-population
#5
Chitra Kannabiran, Mayumi Ueta, Virender Sangwan, Varsha Rathi, Sayan Basu, Katsushi Tokunaga, Shigeru Kinoshita
Stevens Johnson syndrome (SJS) is part of a spectrum of adverse drug reactions resulting in the destruction of skin, mucous membranes, and the ocular surface. A similar, more severe form of the disorder included in this spectrum is toxic epidermal necrolysis (TEN). Approximately 35% of patients suffer chronic sequelae such as vascularization, corneal scarring, conjunctival inversion to the cornea, keratinization, symblepharon, scarring of the palpebral conjunctiva, trichiasis, and severe dry eye. We focused on 80 Indian patients with SJS/TEN with severe ocular complications (SOC) and investigated the association of alleles at HLA -A, HLA-B and HLA-C loci; the controls were 50 healthy Indian volunteers...
November 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29162759/pattern-and-profile-of-children-using-substances-in-india-insights-and-recommendations
#6
Anju Dhawan, Raman Deep Pattanayak, Anita Chopra, V K Tikoo, Rajesh Kumar
India has one of the largest proportion of children and adolescents in the world, but the threat posed by child substance use remains under-researched. Only recently a large study, the first of its kind in India, was carried out with a sample of nearly 4000 children using substances (school-going, out-of-school as well as street children) across more than a hundred cities/towns. We discuss (i) the existing knowledge on the prevalence of child substance abuse in India; (ii) perspectives and insights gained from the recent nation-wide study on its pattern and profile; and (iii) recommendations for substance use prevention and treatment among children in the Indian context...
July 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/29162758/public-health-challenges-for-the-21st-century-convergence-of-demography-economics-environment-and-biology-nalanda-distinguished-lecture
#7
K M Venkat Narayan
The rapidly changing and interdependent world under the mega-force of globalization presents unique challenges and opportunities for public health. Focusing on the example of type 2 diabetes, I argue that an appreciation for the evolution of demographic and economic contexts is essential to appropriately address today's dynamic and complex health challenges. For the vast majority of the past 2000 years, India and China were the world's largest economies until the rise of western European nations in the 18th century and later the USA...
July 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/29162162/a-preliminary-study-of-cross-amplified-microsatellite-loci-using-molted-feathers-from-a-near-threatened-painted-stork-mycteria-leucocephala-population-of-north-india-as-a-dna-source
#8
Bharat Bhushan Sharma, Basu Dev Banerjee, Abdul Jamil Urfi
OBJECTIVE: In continuation of an earlier study in which we reported the cross-amplification of Wood stork microsatellites on the DNA obtained from molted feathers of Painted stork (Mycteria leucocephala), here we investigated the nature of cross-amplified microsatellites and the effect of non-invasive samples on cross-amplification success. In a limited manner, we also addressed the genetic diversity and differentiation in a north Indian population of the Painted Stork examined over three nesting seasons...
November 21, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29161456/integrated-care-with-indigenous-populations-a-systematic-review-of-the-literature
#9
Melissa E Lewis, Laurelle L Myhra
INTRODUCTION: The integration of behavioral health into medical care is related to positive results including improved patient health outcomes, provider satisfaction, and cost-offset. Indigenous people suffer from the highest health disparities in the nation and disproportionately experience barriers to health care; yet it is unknown if integrated care is effective for this population. METHODS: A systematic literature review was completed on the state of integrated care at Indigenous-serving health care sites in 2014 and was updated in 2016...
2017: American Indian and Alaska Native Mental Health Research: the Journal of the National Center
https://www.readbyqxmd.com/read/29161455/responding-to-concerning-posts-on-social-media-insights-and-solutions-from-american-indian-and-alaska-native-youth
#10
Jesse Gritton, Stephanie Craig Rushing, David Stephens, Thomas Ghost Dog, Bradley Kerr, Megan A Moreno
PURPOSE: This study aimed to understand American Indian and Alaska Native (AI/AN) adolescents' perspectives on concerning social media posts, including those expressing suicidal intent. METHODS: A purposive sample of AI/AN youth were recruited; trained facilitators conducted focus groups. Participants discussed experiences viewing concerning posts on social media. Qualitative analysis used the constant comparative method. RESULTS: A total of 32 AI/AN youth ages 14-22 participated...
2017: American Indian and Alaska Native Mental Health Research: the Journal of the National Center
https://www.readbyqxmd.com/read/29161454/religious-and-spiritual-practices-among-home-less-urban-american-indians-and-alaska-natives-with-severe-alcohol-problems
#11
Dennis C Wendt, Susan E Collins, Lonnie A Nelson, Kelly Serafini, Seema L Clifasefi, Dennis M Donovan
Engagement in religious and spiritual practices may be protective for homeless individuals with alcohol-related problems. However, little is known in this regard for urban-dwelling American Indians and Alaska Natives (AI/ANs) who have disproportionately high rates of homelessness and co-occurring alcohol use problems. Using secondary data from a nonrandomized controlled study testing a Housing First intervention, AI/AN participants (n = 52) and non-AI/AN participants (n = 82) were compared on demographic variables, alcohol use problems, religious affiliations, and religious/spiritual practices (importance, frequency, and type)...
2017: American Indian and Alaska Native Mental Health Research: the Journal of the National Center
https://www.readbyqxmd.com/read/29161453/comparison-of-american-indian-and-non-native-basc-2-self-report-adolescent-scores
#12
Georgette Yetter, Victoria M Foutch
BASC-2 SRP-A scores of 162 American Indian (AI) youth were compared with those of an ethnically diverse sample (N = 200) to explore group equivalence. A MANOVA indicated group differences among the five composites. AIs outscored non-Natives in Inattention/Hyperactivity. We examined AIs' ADHD scores in relation to their acculturation strategies, measured using the Bicultural Ethnic Identity Scale. Culturally marginalized AIs (low White and low Indian acculturation) reported stronger ADHD symptoms than bicultural, assimilated, or separated youth...
2017: American Indian and Alaska Native Mental Health Research: the Journal of the National Center
https://www.readbyqxmd.com/read/29161452/psychometric-examination-of-the-center-for-epidemiologic-studies-depression-scale-with-older-american-indians-the-native-elder-care-study
#13
Marc Schure, R Turner Goins
Measuring mental health accurately is an important endeavor for screening purposes. Depression scales, such as the Center for Epidemiologic Studies Depression (CES-D) scale, have been well-established among different populations. Yet, little work has been done to examine the reliability and validity of the CES-D among older American Indians and Alaska Natives. The purpose of our study was to examine the factor structure, reliability, and concurrent validity of the full 20-item and abbreviated 12-item CES-D scale with a sample of older American Indians...
2017: American Indian and Alaska Native Mental Health Research: the Journal of the National Center
https://www.readbyqxmd.com/read/29161443/fragile-x-syndrome-with-congenital-diaphragmatic-hernia
#14
Archana Kadam, Anand Pandit, Sanjay Patole
The authors present a case of Fragile X syndrome (FXS) in siblings from an Indian family with no developmental delay in previous generations. The boy presented with developmental delay, autistic features and defiant behaviours that raised clinical suspicion. He also had congenital diaphragmatic hernia (CDH). Social anxiety and difficulty in making friends were the subtle features in his sister with dull normal intelligence. FXS was confirmed by clinical features and DNA testing. Intervention was initiated for both the siblings...
November 17, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29161285/hpv-genotypes-co-infections-associated-with-cervical-carcinoma-special-focus-on-phylogenetically-related-and-non-vaccine-targeted-genotypes
#15
Rashmirani Senapati, Bhagyalaxmi Nayak, Shantanu Kumar Kar, Bhagirathi Dwibedi
HPV is the major causative agent for cervical cancer. Study on the risk of cervical cancer associated with different hr-HPV genotypes would be useful for disease management and new vaccine strategy. With limited reports available, the present study aimed to investigate the pattern of HPV genotypes coinfections and risk of cervical carcinoma associated with them in Indian population. 15 HPV genotypes were detected by E6/E7 multiplex nested type-specific PCR in the HPV-positive cervical samples of 172 cervical cancer cases and 174 subjects with normal cytology...
2017: PloS One
https://www.readbyqxmd.com/read/29160195/political-boundary-versus-social-context-dynamics-of-socioeconomic-differentials-in-fertility-in-indian-states
#16
Dharma Arunachalam, Kannan Navaneetham, Walter Forrest
Using data from India's first (1992-93) and third (2005-06) National Family Health Surveys (NFHS-I and NFHS-III) this study examined the fertility differentials between major social groups and the extent to which these varied between states and over time. The analysis was based on a sample of 54,030 and 55,369 currently married women aged 15-34 in the NFHS-I and NFHS-III respectively. Reported parity and desired family size were used to assess variations in fertility behaviour. The results show that interstate variation in childbearing patterns within social groups was at least as high as, if not higher than, variation between states (net of other influences) in both periods, 1992-93 and 2005-06...
November 2017: Journal of Biosocial Science
https://www.readbyqxmd.com/read/29159868/tarsal-carpal-coalition-syndrome-report-of-a-novel-missense-mutation-in-nog-gene-and-phenotypic-delineation
#17
Aneek Das Bhowmik, Vijayalakshmi Salem Ramakumaran, Ashwin Dalal
We report a family of Indian origin presenting with Tarsal-carpal coalition syndrome (TCC), which is a rare genetic disorder of skeletal abnormalities, inherited in autosomal dominant manner. In this family, three individuals (mother and two children) were found to be similarly affected with slight intrafamilial individual variability in the phenotype. Sanger sequencing revealed a novel heterozygous missense mutation in NOG gene (NM_005450.4:c.611G>A) in all the affected individuals of the family. Until now only six mutations have been reported in different families affected with TCC syndrome worldwide...
November 21, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29159787/how-can-an-education-workshop-serve-as-an-intervention-for-american-indian-screening-participation
#18
Linda Burhansstipanov, Lisa Harjo, Judith Salmon Kaur
American Indians (AIs) continue to have elevated cancer incidence and mortality, and most have issues accessing cancer screening services. During 2013-2014, Mayo and its partners created Native Cancer 101 Module 10 "Prevention and Early Cancer Detection" education workshop. A community-based AI organization implemented nine of these workshops during 2014-2015 via diverse venues. Nearly all participants eligible for at least one type of cancer screening participated in a workshop and consented to follow-up within 3 to 6 months to determine if screenings had been completed or scheduled...
November 20, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/29159701/residues-of-diclofenac-in-tissues-of-vultures-in-india-a-post-ban-scenario
#19
Kanthan Nambirajan, Subramanian Muralidharan, Aditya A Roy, S Manonmani
Populations of three resident Gyps species (Indian white-backed vulture Gyps bengalensis, Indian vulture Gyps indicus, and Slender-billed vulture Gyps tenuirostris) in India have decreased by more than 90% since mid 1990s, and they continue to decline. Experimental studies showed the mortality of vultures to be due to renal failure caused by diclofenac, a nonsteroidal anti-inflammatory drug. India, Pakistan, and Nepal banned the veterinary usage of diclofenac in 2006 to prevent further decline in vulture population...
November 20, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29159495/lifetime-trauma-and-depressive-symptomatology-among-older-american-indians-the-native-elder-care-study
#20
Ebru Çayır, Michael P Burke, Mindi Spencer, Mark B Schure, R Turner Goins
We examined the association between lifetime traumatic events with or without trauma response symptoms and depressive symptomatology in American Indians aged ≥ 55 years from a tribe in the Southeastern US (N = 362). Twenty-three percent of the sample experienced a traumatic event without trauma-response symptoms, whereas 14% experienced a traumatic event with at least one trauma-response symptom. After adjustment for sociodemographic characteristics and social support, participants who experienced a traumatic event with one or more trauma-response symptoms had higher odds of clinically relevant depressive symptomatology compared to (1) those who never experienced a traumatic event [odds ratio (OR) 3...
November 20, 2017: Community Mental Health Journal
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