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"Multiparameter Intelligent Monitoring in Intensive Care"

Sheng Ye, Dan Xu, Chenmei Zhang, Mengyao Li, Yanyi Zhang
Purpose. The study aimed to investigate the effectiveness of antipyretic therapy on mortality in critically ill patients with sepsis requiring mechanical ventilation. Methods. In this study, we employed the multiparameter intelligent monitoring in intensive care II (MIMIC-II) database (version 2.6). All patients meeting the criteria for sepsis and also receiving mechanical ventilation treatment were included for analysis, all of whom suffer from fever or hyperthermia. Logistic regression model and R language (R version 3...
2017: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
Joon Lee
BACKGROUND: With a large-scale electronic health record repository, it is feasible to build a customized patient outcome prediction model specifically for a given patient. This approach involves identifying past patients who are similar to the present patient and using their data to train a personalized predictive model. Our previous work investigated a cosine-similarity patient similarity metric (PSM) for such patient-specific predictive modeling. OBJECTIVE: The objective of the study is to investigate the random forest (RF) proximity measure as a PSM in the context of personalized mortality prediction for intensive care unit (ICU) patients...
January 17, 2017: JMIR Medical Informatics
Xiao-Dong Zhou, Qin-Fen Chen, Zheng-Xian Wang, Wen-Yue Liu, Sven Van Poucke, Zhi Mao, Sheng-Jie Wu, Wei-Jian Huang, Ming-Hua Zheng
BACKGROUND AND AIM: Acute circulatory failure (ACF) is associated with high mortality rates in critically ill cirrhotic patients. Only a few accurate scoring models exist specific to critically ill cirrhotic patients with acute circulatory failure (CICCF) for mortality risk assessment. The aim was to develop and evaluate a novel model specific to CICCF. PATIENTS AND METHODS: This study collected and analyzed the data on CICCF from the Multiparameter Intelligent Monitoring in Intensive Care-III database...
April 2017: European Journal of Gastroenterology & Hepatology
Yuan-Lan Huang, Zhi-Jun Han, Zhi-De Hu
BACKGROUND: Red blood cell distribution width (RDW) and neutrophil to lymphocyte ratio (NLR) have been reported to be associated with outcomes of acute cerebral infarction. However, their prognostic value in patients with subarachnoid hemorrhage (SAH) remains largely unknown. The aim of this study was to investigate the prognostic value of RDW and NLR in SAH patients. METHODS: Medical records of adult SAH patients admitted to intensive care unit (ICU) were extracted from Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC II, version 2...
December 8, 2016: Annals of Clinical Biochemistry
Wen-Yue Liu, Shi-Gang Lin, Gui-Qi Zhu, Sven Van Poucke, Martin Braddock, Zhongheng Zhang, Zhi Mao, Fei-Xia Shen, Ming-Hua Zheng
BACKGROUND AND AIMS: Recently, glucose variability (GV) has been reported as an independent risk factor for mortality in non-diabetic critically ill patients. However, GV is not incorporated in any severity scoring system for critically ill patients currently. The aim of this study was to establish and validate a modified Simplified Acute Physiology Score II scoring system (SAPS II), integrated with GV parameters and named GV-SAPS II, specifically for non-diabetic critically ill patients to predict short-term and long-term mortality...
2016: PloS One
Zhe He, Neil Charness, Jiang Bian, William R Hogan
Well-designed and well-conducted clinical studies represent gold standard approaches for generating medical evidence. However, elderly populations are systematically underrepresented in studies across major chronic medical conditions, which has hampered the generalizability (external validity) of studies to the real-world patient population. It is the norm that intervention studies often require a homogeneous cohort to test their hypotheses; therefore older adults with co-medications and comorbidities are often excluded...
February 2016: IEEE-EMBS International Conference on Biomedical and Health Informatics
Mohammed M Aboelsoud, Osama Siddique, Alexander Morales, Young Seol, Mazen O Al-Qadi
OBJECTIVES: To investigate the effect of different crystal- loid solutions on clinical outcomes in critically-ill patients with acute pancreatitis (AP). METHODS: We conducted a retrospective study of patients with AP admitted to the ICU using the Multiparameter Intelligent Monitoring in Intensive Care III (MIMIC-III) database. We investigated the effect of fluid type; lactated ringer's (LR) vs. isotonic saline (IS) on hospital mortality rates, and ICU length of stay (LOS)...
October 4, 2016: Rhode Island Medical Journal
Thomas Desautels, Jacob Calvert, Jana Hoffman, Melissa Jay, Yaniv Kerem, Lisa Shieh, David Shimabukuro, Uli Chettipally, Mitchell D Feldman, Chris Barton, David J Wales, Ritankar Das
BACKGROUND: Sepsis is one of the leading causes of mortality in hospitalized patients. Despite this fact, a reliable means of predicting sepsis onset remains elusive. Early and accurate sepsis onset predictions could allow more aggressive and targeted therapy while maintaining antimicrobial stewardship. Existing detection methods suffer from low performance and often require time-consuming laboratory test results. OBJECTIVE: To study and validate a sepsis prediction method, InSight, for the new Sepsis-3 definitions in retrospective data, make predictions using a minimal set of variables from within the electronic health record data, compare the performance of this approach with existing scoring systems, and investigate the effects of data sparsity on InSight performance...
September 30, 2016: JMIR Medical Informatics
David M Maslove, Joel A Dubin, Arvind Shrivats, Joon Lee
OBJECTIVE: To empirically examine the prevalence of errors, omissions, and outliers in hourly vital signs recorded in the ICU. DESIGN: Retrospective analysis of vital signs measurements from a large-scale clinical data warehouse (Multiparameter Intelligent Monitoring in Intensive Care III). SETTING: Data were collected from the medical, surgical, cardiac, and cardiac surgery ICUs of a tertiary medical center in the United States. PATIENTS: We analyzed data from approximately 48,000 ICU stays including approximately 28 million vital signs measurements...
November 2016: Critical Care Medicine
Fernando G Zampieri, Otavio T Ranzani, Luciano Cesar Pontes Azevedo, Izanio D S Martins, John A Kellum, Alexandre B Libório
OBJECTIVES: To assess the impact of the percentage of fluid infused as Lactated Ringer (%LR) during the first 2 days of ICU admission in hospital mortality and occurrence of acute kidney injury. DESIGN: Retrospective cohort. SETTING: Analysis of a large public database (Multiparameter Intelligent Monitoring in Intensive Care-II). PATIENTS: Adult patients with at least 2 days of ICU stay, admission creatinine lower than 5 mg/dL, and that received at least 500 mL of fluid in the first 48 hours...
December 2016: Critical Care Medicine
Mallika L Mundkur, Fiona M Callaghan, Swapna Abhyankar, Clement J McDonald
INTRODUCTION: The current body of literature examining the impact of race upon outcomes for patients admitted to the intensive care unit (ICU) is limited. The primary objective of our study was to explore this question using a large cohort drawn from an electronic health record (EHR)-based data source. METHODS: We conducted a retrospective cohort study using Multiparameter Intelligent Monitoring in Intensive Care (MIMIC-II), an EHR-derived database encompassing ICU admissions to an academic medical center in Boston, Massachusetts, between 2001 and 2008...
June 20, 2016: Journal of Racial and Ethnic Health Disparities
Yuan-Lan Huang, Zhi-De Hu
BACKGROUND: Accumulated studies have shown that hematological parameters [e.g., red blood cell distribution width (RDW), hemoglobin, platelet count] and serum potassium level can impact the prognosis of patients with acute myocardial infarction (AMI). However, no previous study has evaluated the prognostic values of these laboratory tests simultaneously. METHODS: This study is based on an intensive care unit (ICU) database named Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC II)...
May 2016: Annals of Translational Medicine
Krystal Lansdowne, David G Strauss, Christopher G Scully
BACKGROUND: The cacophony of alerts and alarms in a hospital produced by medical devices results in alarm fatigue. The pulse oximeter is one of the most common sources of alarms. One of the ways to reduce alarm rates is to adjust alarm settings at the bedside. This study is aimed to retrospectively examine individual pulse oximeter alarm settings on alarm rates and inter- and intra- patient variability. METHODS: Nine hundred sixty-two previously collected intensive care unit (ICU) patient records were obtained from the Multiparameter Intelligent Monitoring in Intensive Care II Database (Beth Israel Deaconess Medical Center, Boston, MA)...
2016: BMC Nursing
Jacob S Calvert, Daniel A Price, Christopher W Barton, Uli K Chettipally, Ritankar Das
OBJECTIVE: We propose a computational framework for integrating diverse patient measurements into an aggregate health score and applying it to patient stability prediction. MATERIALS AND METHODS: We mapped retrospective patient data from the Multiparameter Intelligent Monitoring in Intensive Care (MIMIC) II clinical database into a discrete multidimensional space, which was searched for measurement combinations and trends relevant to patient outcomes of interest...
January 2017: Journal of the American Medical Informatics Association: JAMIA
M Dustin Boone, Jennifer Massa, Ariel Mueller, Sayuri P Jinadasa, Joon Lee, Rishi Kothari, Daniel J Scott, Julie Callahan, Leo Anthony Celi, Michele R Hacker
PURPOSE: Prior studies report that weekend admission to an intensive care unit is associated with increased mortality, potentially attributed to the organizational structure of the unit. This study aims to determine whether treatment of hypotension, a risk factor for mortality, differs according to level of staffing. METHODS: Using the Multiparameter Intelligent Monitoring in Intensive Care database, we conducted a retrospective study of patients admitted to an intensive care unit at Beth Israel Deaconess Medical Center who experienced one or more episodes of hypotension...
June 2016: Journal of Critical Care
Nazrul Anuar Nayan, Nur Sabrina Risman, Rosmina Jaafar
BACKGROUND: Among vital signs of acutely ill hospital patients, respiratory rate (RR) is a highly accurate predictor of health deterioration. OBJECTIVE: This study proposes a system that consists of a passive and non-invasive single-lead electrocardiogram (ECG) acquisition module and an ECG-derived respiratory (EDR) algorithm in the working prototype of a mobile application. METHOD: Before estimating RR that produces the EDR rate, ECG signals were evaluated based on the signal quality index (SQI)...
July 27, 2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
Max Dunitz, George Verghese, Thomas Heldt
Sepsis, which occurs when an infection leads to a systemic inflammatory response, is believed to contribute to one in two to three hospital deaths in the United States. Using the Multiparameter Intelligent Monitoring in Intensive Care (MIMIC II) database of electronic medical records from Boston's Beth Israel Deaconess Medical Center (BIDMC), we worked to characterize sepsis at BIDMC's intensive care units. Additionally, we developed a real-time algorithm to stratify patients with infectious complaints into different risk categories for progressing to septic shock...
August 2015: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Bing Liu, Qiao Li, Peng Qiu
We aimed to compare simultaneous invasive and non-invasive blood pressure (IBP and NIBP) measurements in young, middle and old age using the data from the Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC II) database. In total, 23,679 blood pressure measurements were extracted from 742 patients, divided into three groups of young, middle and old age. IBP-NIBP differences in systolic/diastolic blood pressure (SBP/DBP) were 0.1 ± 16.5 mmHg/11.0 ± 12.2 mmHg in young age, -2.9 ± 19...
June 2016: Blood Pressure
Tacyano Tavares Leite, Etienne Macedo, Izanio da Silva Martins, Fernanda Macedo de Oliveira Neves, Alexandre Braga Libório
BACKGROUND AND OBJECTIVES: Propofol has been shown to provide protection against renal ischemia/reperfusion injury experimentally, but clinical evidence is limited to patients undergoing cardiac surgery. There are no data about its association with oliguria and AKI in critically ill patients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We obtained data from the Multiparameter Intelligent Monitoring in Intensive Care II database (2001-2008). Patient selection criteria included adult patients in their first intensive care unit (ICU) admission, need for mechanical ventilation, and treatment with propofol or midazolam...
November 6, 2015: Clinical Journal of the American Society of Nephrology: CJASN
Christopher G Scully, Shanti Gomatam, Shawn Forrest, David G Strauss
We assessed the effect of re-calibration time on cardiac output estimation and trending performance in a retrospective analysis of an intensive care unit patient population using error grid analyses. Paired thermodilution and arterial blood pressure waveform measurements (N = 2141) from 222 patient records were extracted from the Multiparameter Intelligent Monitoring in Intensive Care II database. Pulse contour analysis was performed by implementing a previously reported algorithm at calibration times of 1, 2, 8 and 24 h...
October 2016: Journal of Clinical Monitoring and Computing
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