keyword
https://read.qxmd.com/read/37192214/dose-dependent-modulation-of-microglia-activation-in-rats-after-penetrating-traumatic-brain-injury-ptbi-by-transplanted-human-neural-stem-cells
#21
JOURNAL ARTICLE
MaryLourdes Andreu, Nathalie Matti, Helen M Bramlett, Yan Shi, Shyam Gajavelli, W Dalton Dietrich
Traumatic brain injury (TBI) often results in long-lasting patterns of neurological deficits including motor, sensory, and cognitive abnormalities. Cranial gunshot survivors are among the most disabled TBI patients and face a lifetime of disability with no approved strategies to protect or repair the brain after injury. Recent studies using a model of penetrating TBI (pTBI) have reported that human neural stem cells (hNSCs) transplantation can lead to dose and location-dependent neuroprotection. Evidence for regional patterns of microglial activation has also been reported after pTBI with evidence for microglial cell death by pyroptosis...
2023: PloS One
https://read.qxmd.com/read/37182019/gunshot-wound-to-the-posterior-fossa-with-a-transcerebellar-retromesencepahlic-bullet-path-transient-mutism-and-unexpected-functional-recovery-the-pivotal-energy-absorbing-function-of-the-petrous-bone-and-tentorial-leaflet
#22
Sahar Sorek, Aaron Miller, Vincy Mathew, Stephanie Moawad, Ralph Rahme
Given the abundance of vital neurovascular structures, gunshot wounds (GSWs) to the posterior fossa are generally fatal. We present a unique such case where a bullet entered the petrous bone, traversed the cerebellar hemisphere and overlying tentorial leaflet, and reached the dorsal aspect of the midbrain, resulting in transient cerebellar mutism with an unexpectedly favorable functional recovery. A 17-year-old boy sustained a GSW to the left mastoid region with no exit wound and presented with agitation and confusion, ultimately leading to a coma...
April 2023: Curēus
https://read.qxmd.com/read/37025535/proper-ophthalmic-artery-aneurysms
#23
JOURNAL ARTICLE
Philipp Hendrix, Christian Bohan, Shamsher Singh Dalal, Gregory M Weiner, Ulrick S Kanmounye, Clemens M Schirmer, Oded Goren
BACKGROUND: The ophthalmic segment of the internal carotid artery (ICA) represents a common site for cerebral aneurysms. However, aneurysms of the ophthalmic artery (OphA) itself represent rare lesions and have been associated with trauma and flow-related lesions such as arteriovenous fistulas or malformations. Here, we explore clinical and radiological features of four patients managed for five proper ophthalmic artery aneurysms (POAAs). METHODS: Patients undergoing diagnostic cerebral angiogram (DCA) between January 2018 and November 2021 with newly or previously identified POAA were retrospectively reviewed...
2023: Surgical Neurology International
https://read.qxmd.com/read/36996708/a-case-report-of-a-bullet-in-the-breast-of-a-woman-for-four-years-without-any-complications
#24
Osama Al Horani, Basel Al-Ghotani, Douaa Albelal, Ebaa Alabdallah, Hazem Kamil, Souheb Al-Mahasna
INTRODUCTION AND IMPORTANCE: A bullet stabilized in a breast for more than 4 years without causing any complication due to its presence is not a common case. Sometimes breast isolated injury could be seen without symptoms like pain, or palpable mass, or it could present with abscess formation and fistula. In addition, the bullet - if it's small - could mimic calcifications seen in malignancy when performing mammography. CASE PRESENTATION: We report a case of a 46-year-old well-being female who came to resect a superficial gunshot she got in her left breast in one of the armed conflict areas in Syria...
March 24, 2023: International Journal of Surgery Case Reports
https://read.qxmd.com/read/36977988/war-related-traumatic-brain-injuries-during-the-syrian-armed-conflict-in-damascus-2014-2017-a-cohort-study-and-a-literature-review
#25
REVIEW
Ibrahem Hanafi, Eskander Munder, Sulafa Ahmad, Iman Arabhamo, Suzan Alziab, Noor Badin, Ahmad Omarain, Mhd Khaled Jawish, Muhannad Saleh, Vera Nickl, Tamara Wipplinger, Christoph Wipplinger, Robert Nickl
BACKGROUND: The decade-long Syrian armed conflict killed or injured more than 11% of the Syrian population. Head and neck injuries are the most frequent cause of war-related trauma, about half of which are brain injuries. Reports about Syrian brain trauma victims were published from neighboring countries; However, none are available from Syrian hospitals. This study aims to report war-related traumatic brain injuries from the Syrian capital. METHODS: We conducted a retrospective cohort study between 2014 and 2017 at Damascus Hospital, the largest public hospital in Damascus, Syria...
March 29, 2023: BMC Emergency Medicine
https://read.qxmd.com/read/36927798/a-nationwide-analysis-of-gunshot-wounds-of-the-head-and-neck-morbidity-mortality-and-cost
#26
JOURNAL ARTICLE
John M Menezes, Kavita Batra, Vlasdislav Zhitny
BACKGROUND: Gun violence in the United States rose continuously from 2010 to 2022, spiking during the pandemic, and peaking in 2021 at 48,830 deaths (14.8 per 100,000). Previous reports investigated health and financial burden associated with gunshot wounds (GSWs) during 2004 to 2013; however estimates related specifically to head and neck (H&N) injuries have been lacking. This population-based study aims to examine incidence, morbidity, mortality, and health resource utilization of H&N injuries utilizing the Nationwide Inpatient Sample database...
March 17, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36895251/civilian-penetrating-traumatic-brain-injury-a-5-year-single-center-experience
#27
JOURNAL ARTICLE
Omid Yousefi, Pouria Azami, Roham Borazjani, Amin Niakan, Mahnaz Yadollahi, Hosseinali Khalili
BACKGROUND: The aim of this study was to report the demographics and clinical features of patients with penetrating traumatic brain injury (PTBI) during the past 5 years in Rajaee Hospital, a tertiary referral trauma center in Shiraz, southern Iran. METHODS: We conducted a 5-year retrospective evaluation of all patients diagnosed with PTBI who were referred to Rajaee Hospital. We retrieved the following items from the hospital's database and PACS system: patients' demographics, on-admission Glasgow Coma Scale (GCS), presence of trauma to other organs, duration of the hospital and ICU stay, the neurosurgical interventions, any necessity of tracheostomy, duration of ventilator dependency, the entrance point of the trauma in the skull, type of assault, length of trajectory in the brain parenchyma, the number of remaining objects in the brain, the occurrence of any hemorrhagic phenomenon, the cross of the bullet from the midline or coronal suture, and the presence of the pneumocephalus...
2023: Surgical Neurology International
https://read.qxmd.com/read/36813646/neurologically-intact-survival-after-bihemispheric-penetrating-head-trauma-a-case-report
#28
JOURNAL ARTICLE
Taylor Reffett, Shubhro Bose, Thomas C Frawley
BACKGROUND: Patients with penetrating head trauma that crosses the midline of the brain have a high mortality rate; most die in the prehospital setting or during initial resuscitative efforts. However, surviving patients are often neurologically intact and several factors other than bullet path, including post-resuscitation Glasgow Coma Scale, age, and pupillary abnormalities, must be considered in aggregate when prognosticating patients. CASE REPORT: We present a case of an 18-year-old man who presented unresponsive after a single gunshot wound to the head that traversed the bilateral hemispheres...
February 20, 2023: Journal of Emergency Medicine
https://read.qxmd.com/read/36751449/retrograde-cranio-orbital-penetrating-injury-a-case-report
#29
Al-Mutasim B Etaiwi, Mustafa Ismail, Teeba A Al-Ageely, Ayaat F Alasady, Alsultan O Jabbar, Jaafar AbdulWahid, Mahmood F Al-Zaidy, Samer S Hoz
BACKGROUND: Transorbital (Orbito-cranial) injuries are uncommon, but they are among the most debilitating types of traumatic brain injury (TBI), mainly caused by high-velocity gunshot wounds. In addition, the management of transorbital TBI is well documented in the literature. In contrast, the cranio-orbital migration of a bullet following TBI is rarely reported. In this article, we report a reverse cranio-orbital penetration of a bullet after a TBI from the occiput with a discussion about its management...
2023: Surgical Neurology International
https://read.qxmd.com/read/36534621/-metallic-foreign-bodies-of-brain-ventricles
#30
JOURNAL ARTICLE
A V Stanishevsky, Z Sh Aliev, Sh Kh Gizatullin, A A Rafaelyan, D V Svistov, G V Gavrilov, I E Onnitsev
UNLABELLED: Head injuries are often associated with intracranial foreign bodies that require decision making on the need for certain surgical treatment. Intraventricular foreign bodies are rare, so the question of surgical tactics is still open. OBJECTIVE: To summarize the experience of treating the wounded with intraventricular foreign bodies. MATERIAL AND METHODS: Treatment outcomes in victims with foreign bodies in lateral ventricles are presented...
2022: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://read.qxmd.com/read/36352597/country-made-firearm-desi-katta-related-cranial-injuries-an-institutional-experience
#31
JOURNAL ARTICLE
Dibyajyoti Mahakul, Ramesh S Doddamani, Rajesh K Meena, Dattaraj Sawarkar, Rajeev Sharma, Shweta Kedia, Deepak Gupta, Satish Verma, Pankaj K Singh, Deepak Agrawal, Manmohan Singh, Poodipedi S Chandra, Shashank S Kale
Background: Approximately, 80% of civilian cranial gunshot injuries in India are mainly due to unlicensed mostly country-made guns, called the "Desi-Kattas," manufactured by the traditional gunsmiths. These injuries constitute a unique subgroup, with respect to the make and design along with the unique wound ballistics compared to the factory-made firearms. Objective: This study is aimed at defining the prognostic factors in predicting the outcomes related to cranial gunshot injuries due to these desi-kattas...
September 2022: Neurology India
https://read.qxmd.com/read/36267559/violent-injury-prevention-does-not-equal-to-violent-crime-prevention-an-analysis-of-violence-intervention-program-efficacy-using-propensity-score-methods
#32
JOURNAL ARTICLE
Emma Holler Mph, Damaris Ortiz Md, Sanjay Mohanty Md Ms, Ashley D Meagher Md Mph, Malaz Boustani Md Mph, Ben L Zarzaur Md Mph, Clark J Simons Md
Objective: The purpose of this study was to determine if exposure to Prescription for Hope (RxH), a hospital-based violence intervention program (HVIP), is associated with reduced violent reinjury and new convictions for violent crime in the 2-year period after index hospitalization for a violent injury. Methods: This was a retrospective cohort study analyzing patients from two level I trauma centers in Indianapolis, Indiana. RxH participants (n=260) enrolled between January 1, 2015 and December 31, 2018 and who had trauma registry data were included...
2022: Trauma Surgery & Acute Care Open
https://read.qxmd.com/read/36261235/predictive-value-of-tachycardia-for-mortality-in-trauma-related-haemorrhagic-shock-a-systematic-review-and-meta-regression
#33
JOURNAL ARTICLE
Péter Jávor, Lilla Hanák, Péter Hegyi, Endre Csonka, Edina Butt, Tamara Horváth, István Góg, Anita Lukacs, Alexandra Soós, Zoltán Rumbus, Eszter Pákai, János Toldi, Petra Hartmann
OBJECTIVES: Heart rate (HR) is one of the physiological variables in the early assessment of trauma-related haemorrhagic shock, according to Advanced Trauma Life Support (ATLS). However, its efficiency as predictor of mortality is contradicted by several studies. Furthermore, the linear association between HR and the severity of shock and blood loss presented by ATLS is doubtful. This systematic review aims to update current knowledge on the role of HR in the initial haemodynamic assessment of patients who had a trauma...
October 19, 2022: BMJ Open
https://read.qxmd.com/read/36163460/study-on-protective-performance-and-gradient-optimization-of-helmet-foam-liner-under-bullet-impact
#34
JOURNAL ARTICLE
Xingyuan Huang, Qiujie Zheng, Lijun Chang, Zhihua Cai
Protective equipment in war plays a vital role in the safety of soldiers, the threat to soldiers from brain damage caused by deformation at the back of the helmet cannot be ignored, so research on reduce blunt post-cranial injury has great significance and value. This study first conducted gunshot experiments, used rifle bullets impact bulletproof plate and different density liner foam to record the incident process and internal response of craniocerebral model. After verifying the accuracy of finite element model through experimental data, optimization model is established based on response surface method to optimize the structure of gradient foam, analyze the cranial strain and energy absorption to select the best density and thickness distribution of each foam layer...
September 26, 2022: Scientific Reports
https://read.qxmd.com/read/36130545/wound-vacuum-assisted-closure-as-a-bridge-therapy-in-the-treatment-of-infected-cranial-gunshot-wound-in-a-pediatric-patient-illustrative-case
#35
JOURNAL ARTICLE
Harjus Birk, Audrey Demand, Sandeep Kandregula, Christina Notarianni, Andrew Meram, Jennifer Kosty
BACKGROUND: The authors reported the first pediatric case of a craniocerebral gunshot injury successfully treated with a wound vacuum-assisted closure (VAC) device after dehiscence and infection of the initial cranial wound. OBSERVATIONS: A 17-year-old boy suffered several gunshots to the left hemisphere, resulting in significant damage to the scalp, calvaria, and brain. Emergency hemicraniectomy was performed, with reconstruction of a complicated scalp wound performed at the initial surgery...
February 21, 2022: J Neurosurg Case Lessons
https://read.qxmd.com/read/36068101/characteristics-of-fatal-penetrating-injury-data-from-a-retrospective-cohort-study-in-three-urban-regions-in-the-netherlands
#36
JOURNAL ARTICLE
N A G Hakkenbrak, E R Bakkum, W P Zuidema, J A Halm, T Dorn, U J L Reijnders, G F Giannakopoulos
INTRODUCTION: Penetrating injury (PI) is a relatively rare mechanism of trauma in the Netherlands. Nevertheless, injuries can be severe with high morbidity and mortality rates. The aim of this study is to assess fatalities due to PI and evaluate the demographic parameters, mechanism of injury and the resulting injury patterns of this group of patients in three Dutch regions. METHODS: Patients suffering fatal PI (stab- and gunshot injuries), in the period between July 1st 2013 and July 1st 2019, in the region of Amsterdam, Utrecht and The Hague were included...
August 19, 2022: Injury
https://read.qxmd.com/read/36052629/from-henry-shrapnel-1761-1842-to-today-s-neurosurgery-how-antipersonnel-weapons-have-laid-the-foundation-of-clinical-and-surgical-management-of-head-injury-fractures-and-penetrating-brain-injuries
#37
JOURNAL ARTICLE
Maria Sole Venanzi, Gianluca Piatelli, Marco Pavanello
Henry Shrapnel invented an antipersonnel weapon capable of defragmenting with the explosion of charge. Modern grenades or improvised explosive devices may be seen as an evolution of Shrapnel's ammunition. Starting by analyzing the ballistics of these weapons, it is possible to understand the historical evolution of the management of skull fractures and penetrating brain injuries (PBIs). A circular crack line with a splinter at the center, depressed in bone, was a characteristic feature of fractures due to Shrapnel's bullet...
September 2022: Neurosurgical Focus
https://read.qxmd.com/read/35926251/a-comparison-of-clinical-characteristics-radiographic-findings-and-outcomes-of-bihemispheric-versus-unihemispheric-gunshot-wounds-to-the-head
#38
JOURNAL ARTICLE
Genna Beattie, Caitlin M Cohan, Emma A Smith, Sun I Lee, Margaret Riordan
INTRODUCTION: Unihemispheric head gunshot wound (HGSW) are associated with improved survival; however, specific clinical and radiographic characteristics associated with survival have not been clearly defined. To further guide prognosis estimates and care discussions, this study aims to identify unihemispheric HGSWs injury patterns; comparing them to bihemispheric HGSWs characterizing factors associated with improved clinical outcomes and survival. METHODS: Patients presenting to our Level 1 trauma center from January 2013 through May 2019 with HGSW injury were reviewed...
October 2022: American Journal of Emergency Medicine
https://read.qxmd.com/read/35901757/simple-wound-closure-compared-with-surgery-for-civilian-cranial-gunshot-wounds
#39
JOURNAL ARTICLE
Evan M Krueger, Ronald J Benveniste, Victor M Lu, Ruby R Taylor, Rahul Kumar, Joacir G Cordeiro, Jonathan R Jagid
OBJECTIVE: A carefully selected subset of civilian cranial gunshot wound (CGSW) patients may be treated with simple wound closure (SWC) as a proactive therapy, but the appropriate clinical scenario for using this strategy is unknown. The aim of this study was to compare SWC and surgery patients in terms of their neurological outcomes and complications, including infections, seizures, and reoperations. METHODS: This was a single-center, retrospective review of the prospectively maintained institutional traumatic brain injury and trauma registries...
June 24, 2022: Journal of Neurosurgery
https://read.qxmd.com/read/35755225/racial-and-social-determinants-of-civilian-gunshot-wounds-to-the-head
#40
JOURNAL ARTICLE
Myron L Rolle, Rachel M McLellan, Pranav Nanda, Aman B Patel, Chana A Sacks, Peter T Masiakos, Christopher J Stapleton
Objective: To assess the clinical, racial, and social characteristics of victims of Gunshot wounds (GSWs) to the head and assess for associations between these factors and outcomes. Summary Background Data: Previous literature has not focused on the association of race and socioeconomic factors with these specific injuries. Methods: We identified patients with GSWs to the head who presented to 2 urban academic medical centers between 1998 and 2020, and extracted patient-level demographic data, information about the clinical and surgical course, and outcomes at discharge and follow-up...
July 2022: Neurohospitalist
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