Jianwei Wang, Hongli Yin, Gen Li, Di Wu, Yunyun Xu, Yanling Chen, Xiaodong Wang, Yujiao Xing, Ting Zhang, Danhong Fei, Pengcheng Yang, Fang Fang, Yanfang Tao, Xiaolu Li, Juanjuan Yu, Yang Yang, Zhiheng Li, Lei Shi, Zimu Zhang, Jian Pan
Neuroblastoma (NB) is a common childhood tumor with a high incidence worldwide. The regulatory role of RNA N6-methyladenosine (m6A) in gene expression has attracted significant attention, and the impact of methyltransferase-like 14 (METTL14) on tumor progression has been extensively studied in various types of cancer. However, the specific influence of METTL14 on NB remains unexplored. Using data from the Target database, our study revealed significant upregulation of METTL14 expression in high-risk NB patients, with strong correlation with poor prognosis...
April 22, 2024: Cell Death Discovery