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https://www.readbyqxmd.com/read/29029132/general-practitioners-strategies-in-consultations-with-immigrants-in-norway-practice-based-shared-reflections-among-participants-in-focus-groups
#1
Stefán Hjörleifsson, Elise Hammer, Esperanza Díaz
Background: Immigrants comprise 16.8% of the population in Norway and meet General Practitioners (GPs) as their first point of contact with most health care services as do others in Norway. While Norwegian GPs are not trained in cultural competence, little is known about the extent to which they see good care for immigrants as relying on specific strategies. Objectives: To explore the thoughts of GPs in Norway about strategies they might use with immigrant patients...
September 28, 2017: Family Practice
https://www.readbyqxmd.com/read/29025216/assisted-salvage-of-ischemic-fasciocutaneous-flap-using-adipose-derived-mesenchymal-stem-cells-in-situ-revascularization
#2
Michael H Carstens, Mauricio Mendieta, Cecilia Pérez, Esperanza Villareal, Rodolfo Garcia
Adipose-derived mesenchymal stem cells (ASCs) have been shown to produce vascular endothelial growth factor (VEGF) and can increase perfusion in patients with critical limb ischemia. We will show that this concept can be applied to augment blood flow in zones of flap ischemia. We presented a case study of a 26-year-old man with a complex hand injury covered by a reverse radial perforator fasciocutaneous flap, which developed ischemic necrosis and was treated by debridement, transplantation of ASCs to enhance vascular support, and saline dressings...
July 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29023524/polymorphism-il-1rn-rs419598-reduces-the-susceptibility-to-generalized-periodontitis-in-a-population-of-european-descent
#3
Francisco Mesa, Esperanza Lanza, Llenalia García, Rafael Marfil-Alvarez, Antonio Magan-Fernandez
Interleukin (IL) 1-ra is a potent endogenous competitive inhibitor of IL-α and β and has an anti-inflammatory role. Study objectives were: 1) to assess the associations of IL-1RN genetic single nucleotide polymorphism (SNP) (rs419598) with generalized chronic periodontitis (GCP), generalized aggressive periodontitis (GAgP), and absence of periodontitis and 2) to assess its association with the load of five periodontopathogenic bacteria and periodontal clinical variables. A cross-sectional analytic study was conducted in 123 patients with GCP, 60 patients with GAgP, and 20 controls...
2017: PloS One
https://www.readbyqxmd.com/read/29016284/is-visceral-leishmaniasis-different-in-immunocompromised-patients-without-human-immunodeficiency-virus-a-comparative-multicenter-retrospective-cohort-analysis
#4
José M Ramos, Rafael León, Esperanza Merino, Marta Montero, Asunción Aljibe, Marino Blanes, Sergio Reus, Vicente Boix, Miguel Salavert, Joaquín Portilla
Although visceral leishmaniasis (VL) can affect immunocompromised patients, data from the human immunodeficiency virus (HIV) infection context are limited, and the characteristics of VL in other immunosuppression scenarios are not well defined. A retrospective review of all cases of VL in immunocompromised patients from January 1997 to December 2014 in two Spanish hospitals on the Mediterranean coast was performed. We included 18 transplant recipients (kidney: 7, liver: 4, lung: 3, heart: 2, and blood marrow: 2), 12 patients with other causes of immunosuppression (myasthenia gravis: 3 and rheumatoid arthritis: 2), and 73 VL HIV-positive patients...
September 5, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28993045/-the-pharmaceutical-industry-and-specialised-medical-training-residents-perceptions-in-madrid-spain
#5
Raquel González-Rubio, Esperanza Escortell-Mayor, Isabel Del Cura González
OBJECTIVE: To assess the frequency of exposure and attitudes to the pharmaceutical industry (PI) of residents in the Region of Madrid (RM), Spain, and to analyse the association with specialty, professional environment and training. METHODS: Cross-sectional electronic survey in May and June 2015 of all medical residents in RM. We collected sociodemographic variables and those of interaction with the PI in four blocks: frequency of interactions, attitudes and perceptions, environment and regulatory framework, and skills; with the first two blocks we created a Synthetic PI Interaction Index (SPIII)...
October 6, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28992553/validity-of-instruments-for-measuring-the-satisfaction-of-a-woman-and-her-partner-with-care-received-during-labour-and-childbirth-systematic-review
#6
REVIEW
Ruben Alfaro Blazquez, Silvia Corchon, Esperanza Ferrer Ferrandiz
BACKGROUND: patient satisfaction as an indicator of quality of care is becoming more and more important. The use of questionnaires is the most common method to evaluate satisfaction with maternity care. Despite the extensive variety of instruments available for this purpose, they vary widely in terms of their content and quality. OBJECTIVES: to identify, assess and summarize the most recent and robust instruments available to measure woman and partner satisfaction with the overall package of care during the labour and birth of their baby within a hospital setting...
September 21, 2017: Midwifery
https://www.readbyqxmd.com/read/28973255/could-the-fight-against-treatment-failures-in-giardiasis-lead-to-a-second-childhood-for-quinacrine
#7
Angel A Escobedo, Pedro Almirall, Alfonso J Rodríguez-Morales, Esperanza Duquesne-Rivero, Roberto Suarez-Mella, Eduardo Ruiz-Blanco
No abstract text is available yet for this article.
August 3, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28972100/actinomycetoma-a-therapeutic-challenge
#8
Sylvia Aide Martínez-Cabriales, Jorge Ocampo-Candiani, Esperanza Welsh, Ana Sofía Ayala-Cortés, Minerva Gómez-Flores, Oliverio Welsh
No abstract text is available yet for this article.
September 29, 2017: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/28971826/the-implementation-of-the-plan-esperanza-and-response-to-the-impact-review
#9
REVIEW
Tatiana Vidaurre, Carlos Santos, Henry Gómez, Gustavo Sarria, Edgar Amorin, Marga López, Roxana Regalado, Javier Manrique, Duniska Tarco, Carlos Ayestas, Mónica Calderón, Luis Mas, Silvia Neciosup, Miriam Salazar, Juan Carlos Chávez, Milward Ubillus, Abel Limache, José Carlos Ubillus, Jeannie Navarro, Kavita Sarwal, Simon Sutcliffe, Alfonso Gutiérrez-Aguado, Marianela Silva, Amalia Mena, María Eugenia Guillén, Carlos Castañeda, Julio Abugattas
Following the implementation of the National Cancer Prevention and Control Results-based Budget Programme (PpR Cancer-024) in 2011, the Peruvian Government approved the Plan Esperanza-a population-based national cancer control plan-in 2012. Legislation that ensured full government-supported funding for people who were otherwise unable to access or afford care and treatment accompanied the Plan. In 2013, the Ministry of Health requested an integrated mission of the Programme of Action for Cancer Therapy (imPACT) report to strengthen cancer control in Peru...
October 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28971614/surveillance-study-on-the-tolerability-and-safety-of-flebogamma-%C3%A2-dif-10-and-5-intravenous-immunoglobulin-in-adult-and-pediatric-patients
#10
Laia Alsina, Andreas Mohr, Maria Montañés, Xènia Oliver, Esperanza Martín, Jaime Pons, Elizabeth Drewe, Jens Papke, Georg Günther, Ronnie Chee, Mark Gompels
Direct comparisons of tolerability and safety of concentrated intravenous immunoglobulin (IVIG) versus less concentrated products are scarce. In this postauthorization, prospective, observational, multicenter study, a systematic comparison of 10% and 5% concentrations of Flebogamma® DIF IVIG was performed in both adult and pediatric patients treated with the studied IVIG products according to the approved indications under routine conditions. Dose of product administered, adverse events (AEs), physical assessments, laboratory tests, and concomitant therapy were analyzed...
October 2017: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/28954265/differential-detection-of-enterovirus-and-herpes-simplex-virus-in-cerebrospinal-fluid-by-real-time-rt-pcr
#11
Brenda Sarquiz-Martínez, César R González-Bonilla, Clara Esperanza Santacruz-Tinoco, José E Muñoz-Medina, Héctor D Pardavé-Alejandre, Elizabeth Barbosa-Cabrera, José Ernesto Ramírez-González, José Alberto Díaz-Quiñonez
BACKGROUND: Enterovirus (EV) and herpes simplex virus 1 and 2 (HSV1 and HSV2) are the main etiologic agents of central nervous system infections. Early laboratory confirmation of these infections is performed by viral culture of the cerebrospinal fluid (CSF), or the detection of specific antibodies in serum (e.g., HSV). The sensitivity of viral culture ranges from 65 to 75%, with a recovery time varying from 3 to 10 days. Serological tests are faster and easy to carry out, but they exhibit cross-reactivity between HSV1 and HSV2...
September 28, 2017: Intervirology
https://www.readbyqxmd.com/read/28951193/impact-of-toxicity-on-survival-for-older-adult-patients-after-cd34-selected-allogeneic-hematopoietic-stem-cell-transplantation
#12
Gunjan L Shah, Michael Scordo, Satyajit Kosuri, Diego Adrianzen Herrera, Christina Cho, Molly A Maloy, Jimmy Nieves, Sean M Devlin, Taylor Borrill, Dean C Carlow, Scott T Avecilla, Richard C Meagher, Richard J O'Reilly, Ann A Jakubowski, Esperanza B Papadopoulos, Guenther Koehne, Boglarka Gyurkocza, Hugo Castro-Malaspina, Brian C Shaffer, Miguel-Angel Perales, Sergio A Giralt, Roni Tamari
Ex vivo CD 34+ selection prior to allogeneic hematopoietic stem Cell transplantation (allo-HCT) reduces GVHD without increasing relapse, but usually requires myeloablative conditioning. We aimed to identify toxicity patterns in older patients & the association with overall survival (OS) & non-relapse mortality (NRM). We conducted a retrospective analysis of 200 pts who underwent CD34+ selection allo-HCT using the ClinicMACS® system between 2006-2012. All grade 3-5 toxicities by CTCAE v4.0 were collected. Eighty patients ≥ 60yrs with a median age of 64 (range 60-73) were compared to 120 pts <60yrs...
September 22, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28948984/scoring-ultrasound-synovitis-in-rheumatoid-arthritis-a-eular-omeract-ultrasound-taskforce-part-2-reliability-and-application-to-multiple-joints-of-a-standardised-consensus-based-scoring-system
#13
Lene Terslev, Esperanza Naredo, Philippe Aegerter, Richard J Wakefield, Marina Backhaus, Peter Balint, George A W Bruyn, Annamaria Iagnocco, Sandrine Jousse-Joulin, Wolfgang A Schmidt, Marcin Szkudlarek, Philip G Conaghan, Emilio Filippucci, Maria Antonietta D'Agostino
OBJECTIVES: To test the reliability of new ultrasound (US) definitions and quantification of synovial hypertrophy (SH) and power Doppler (PD) signal, separately and in combination, in a range of joints in patients with rheumatoid arthritis (RA) using the European League Against Rheumatisms-Outcomes Measures in Rheumatology (EULAR-OMERACT) combined score for PD and SH. METHODS: A stepwise approach was used: (1) scoring static images of metacarpophalangeal (MCP) joints in a web-based exercise and subsequently when scanning patients; (2) scoring static images of wrist, proximal interphalangeal joints, knee and metatarsophalangeal joints in a web-based exercise and subsequently when scanning patients using different acquisitions (standardised vs usual practice)...
2017: RMD Open
https://www.readbyqxmd.com/read/28948983/scoring-ultrasound-synovitis-in-rheumatoid-arthritis-a-eular-omeract-ultrasound-taskforce-part-1-definition-and-development-of-a-standardised-consensus-based-scoring-system
#14
Maria-Antonietta D'Agostino, Lene Terslev, Philippe Aegerter, Marina Backhaus, Peter Balint, George A Bruyn, Emilio Filippucci, Walter Grassi, Annamaria Iagnocco, Sandrine Jousse-Joulin, David Kane, Esperanza Naredo, Wolfgang Schmidt, Marcin Szkudlarek, Philip G Conaghan, Richard J Wakefield
OBJECTIVES: To develop a consensus-based ultrasound (US) definition and quantification system for synovitis in rheumatoid arthritis (RA). METHODS: A multistep, iterative approach was used to: (1) evaluate the baseline agreement on defining and scoring synovitis according to the usual practice of different sonographers, using both grey-scale (GS) (synovial hypertrophy (SH) and effusion) and power Doppler (PD), by reading static images and scanning patients with RA and (2) evaluate the influence of both the definition and acquisition technique on reliability followed by a Delphi exercise to obtain consensus definitions for synovitis, elementary components and scoring system...
2017: RMD Open
https://www.readbyqxmd.com/read/28941692/extensive-profiling-of-three-varieties-of-opuntia-spp-fruit-for-innovative-food-ingredients
#15
Bruno Melgar, Eliana Pereira, M Beatriz P P Oliveira, Esperanza M Garcia-Castello, Antonio D Rodriguez-Lopez, Marina Sokovic, Lillian Barros, Isabel C F R Ferreira
Consumer interest in the use of natural ingredients is creating a growing trend in the food industry, leading to research into the development of natural products such as colorants, antimicrobials and antioxidant compounds. This work involves an extensive morphological (using physico-chemical assays), chemical (antioxidant activity assays) and microbiological (Gram-positive and negative strains) characterization of prickly peras (Opuntia ficus-indica (OFI) var. sanguigna, gialla and Opuntia engelmannii) fruits...
November 2017: Food Research International
https://www.readbyqxmd.com/read/28939450/prediction-of-recurrent-clostridium-difficile-infection-at-the-bedside-the-geih-cdi-score
#16
Javier Cobo, Esperanza Merino, Cristina Martínez, Alberto Cózar-Llistó, Evelyn Shaw, Teresa Marrodán, Esther Calbo, Elena Bereciartúa, Luis A Sánchez-Muñoz, Miguel Salavert, M Teresa Pérez-Rodríguez, Dácil García-Rosado, J María Bravo-Ferrer, Juan Gálvez-Acebal, César Henríquez-Camacho, Jordi Cuquet, Berta Pino-Calm, Luis Torres, Antonio Sánchez-Porto, Borja M Fernández-Félix
Recurrence of Clostridium difficile infection (CDI) has major consequences for both patients and the health system. The ability to predict which patients are at an increased risk of recurrent CDI makes it possible to select candidates for therapy with new drugs and therapies (including fecal microbiota transplantation) that have proven to reduce the incidence of recurrence of CDI. Our objective was to develop a clinical prediction tool, the GEIH-CDI score, to determine the risk of recurrence of CDI. Predictors of recurrence of CDI were investigated using logistic regression in a prospective cohort of 274 patients diagnosed with CDI...
September 19, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28937428/progressive-cutaneous-lesions-in-a-young-girl-challenge
#17
Ines Escandell, Jose M Martin, Catalina Torres, Pilar Cordero, Esperanza Jorda, Carlos Monteagudo
No abstract text is available yet for this article.
September 12, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28935693/a-multidimensional-blood-stimulation-assay-reveals-immune-alterations-underlying-systemic-juvenile-idiopathic-arthritis
#18
Alma-Martina Cepika, Romain Banchereau, Elodie Segura, Marina Ohouo, Brandi Cantarel, Kristina Goller, Victoria Cantrell, Emily Ruchaud, Elizabeth Gatewood, Phuong Nguyen, Jinghua Gu, Esperanza Anguiano, Sandra Zurawski, Jeanine M Baisch, Marilynn Punaro, Nicole Baldwin, Gerlinde Obermoser, Karolina Palucka, Jacques Banchereau, Sebastian Amigorena, Virginia Pascual
The etiology of sporadic human chronic inflammatory diseases remains mostly unknown. To fill this gap, we developed a strategy that simultaneously integrates blood leukocyte responses to innate stimuli at the transcriptional, cellular, and secreted protein levels. When applied to systemic juvenile idiopathic arthritis (sJIA), an autoinflammatory disease of unknown etiology, this approach identified gene sets associated with specific cytokine environments and activated leukocyte subsets. During disease remission and off treatment, sJIA patients displayed dysregulated responses to TLR4, TLR8, and TLR7 stimulation...
September 21, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28935122/prevalence-of-exocrine-pancreatic-insufficiency-in-patients-with-chronic-pancreatitis-without-follow-up-pancr-evol-study
#19
Carlos Marra-Lopez Valenciano, Federico Bolado Concejo, Eva Marín Serrano, Judith Millastre Bocos, Emma Martínez-Moneo, Esperanza Pérez Rodríguez, María Francisco González, Andrés Del Pozo-García, Anaiansi Hernández Martín, Elena Labrador Barba, María Luisa Orera Peña, Enrique de-Madaria
BACKGROUND/OBJECTIVES: Exocrine pancreatic insufficiency (EPI) is an important complication of chronic pancreatitis (CP). Guidelines recommend to rule out EPI in CP, to detect those patients who would benefit from pancreatic enzyme replacement therapy. The aim of this study was to evaluate the prevalence of EPI in patients with CP without follow-up in the last 2 years and to describe their nutritional status and quality of life (QoL). METHODS: This was a cross-sectional, multicenter Spanish study...
September 18, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/28933861/differential-effect-of-bilayer-thickness-on-sticholysin-activity
#20
Juan Palacios-Ortega, Sara García-Linares, Esperanza Rivera-de-Torre, José G Gavilanes, Álvaro Martínez-Del-Pozo, J Peter Slotte
In this study, we examined the influence of bilayer thickness on the activity of the actinoporin toxins sticholysin I and II (StnI and StnII) at 25 °C. Bilayer thickness was varied using dimonounsaturated phosphatidylcholine (PC) analogues (with 14:1, 16:1, 18:1, 20:1, and 22:1 acyl chains). In addition, N-14:0-sphingomyelin (SM) was always included because StnI and StnII are SM specific. Cholesterol was also incorporated as indicated. In cholesterol-free large unilamellar vesicles (LUVs) the PC:SM molar ratio was 4:1, and when cholesterol was included, the complete molar ratio was 4:1:0...
October 17, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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