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Céline Ledoux, Eva Pilot, Esperanza Diaz, Thomas Krafft
BACKGROUND: The current migration flow into Europe is leading to a growing ethnically diverse population in many European countries. Now more than ever, those populations have different healthcare needs, languages, traditions, and previous level of care. This higher level of diversity is likely to increase health inequalities that might challenge healthcare systems if not addressed. In this context, this study aims at reviewing the policy framework for migrants' access to healthcare in Spain, Portugal and Ireland, countries with a long history of immigration, to identify lessons to be learned for policies on migrants' health...
June 15, 2018: Globalization and Health
Signed Esperanza Prieto Bohórquez, Javier Oswaldo Rodríguez Velásquez, Catalina Correa Herrera, Juan Mauricio Pardo Oviedo, Javier Ardila
Introducción: una ley exponencial se ha hallado para los sistemas dinámicos caóticos cardiacos, logrando cuantificar las diferencias entre dinámicas cardiacas normales y  patológicas.Metodología: Se analizaron 120 registros electrocardiográficos, 40 correspondían a sujetos dentro de los límites de normalidad y 80 con diferentes patologías. Para cada holter se analizaron los atractores generados con los datos durante 18 horas y durante toda la dinámica. Se calculó la dimensión fractal del atractor y su ocupación espacial...
March 23, 2018: Revista de la Facultad de Ciencias Médicas
César Vargas-Blasco, Esperanza L Gómez-Durán, Carles Martin-Fumadó, Josep Arimany-Manso
OBJECTIVES: Data about urology malpractice claims in our environment are scarce and should be considered a potential opportunity to "learn from errors". METHODS: We analyzed every claim for alleged malpractice in Urology managed by the Council of Medical Colleges of Catalonia between 1990 and 2012, and specifically evaluated the clinical and medicolegal features of those cases with medical professional responsibility. RESULTS: We identified 182 cases in 22 years, but only the 25,74%showed professional liability...
June 2018: Archivos Españoles de Urología
Pedro Villanueva, Alfonso Arteaga, Javier Fernández-Montalvo
OBJECTIVES: The main goals of this study were to determine the prevalence rate of suicidal ideation among callers to a Spanish telephone helpline (Teléfono de la Esperanza) and to identify gender-based characteristics and risk factors related to suicidal ideation. METHOD: A sample of 10,765 (6,868 men and 3,897 women) callers to this telephone helpline was assessed. ATENSIS, an assessment tool designed to collect information related to suicidal ideation among callers to telephone helplines, was used...
June 8, 2018: Archives of Suicide Research: Official Journal of the International Academy for Suicide Research
Stavros Chrysidis, Christina Duftner, Christian Dejaco, Valentin S Schäfer, Sofia Ramiro, Greta Carrara, Carlo Alberto Scirè, Alojzija Hocevar, Andreas P Diamantopoulos, Annamaria Iagnocco, Chetan Mukhtyar, Cristina Ponte, Esperanza Naredo, Eugenio De Miguel, George A Bruyn, Kenneth J Warrington, Lene Terslev, Marcin Milchert, Maria Antonietta D'Agostino, Mattew J Koster, Naina Rastalsky, Petra Hanova, Pierluigi Macchioni, Tanaz A Kermani, Tove Lorenzen, Uffe Møller Døhn, Ulrich Fredberg, Wolfgang Hartung, Bhaskar Dasgupta, Wolfgang A Schmidt
Objectives: To define the elementary ultrasound (US) lesions in giant cell arteritis (GCA) and to evaluate the reliability of the assessment of US lesions according to these definitions in a web-based reliability exercise. Methods: Potential definitions of normal and abnormal US findings of temporal and extracranial large arteries were retrieved by a systematic literature review. As a subsequent step, a structured Delphi exercise was conducted involving an expert panel of the Outcome Measures in Rheumatology (OMERACT) US Large Vessel Vasculitis Group to agree definitions of normal US appearance and key elementary US lesions of vasculitis of temporal and extracranial large arteries...
2018: RMD Open
Luis Fernando Barba Gallardo, Martín Humberto Muñoz Ortega, Javier Ventura Juarez, Liseth Rubí Aldaba Muruato, Esperanza Sánchez Alemán, Eduardo Emmanuel Valdez Morales, Sugela Susana Blancas Zugarazo, Jose Rafael Villafan Bernal
Prolonged and continuous use of contact lenses for as long as 3 or 4 weeks is common in Mexico due to the low socioeconomic status, poor patient education and self-neglect. Furthermore, wearing contact lenses with low oxygen permeability is common due to their low cost. Thus, patients seek ophthalmologic evaluation due to signs and symptoms of overuse such as red eye, discomfort and tearing. In the present study, the effect of wearing soft contact lenses with a low oxygen permeability on the tear fluid composition after 1 day, 1 week and 1 month without removing them was examined...
May 2018: Experimental and Therapeutic Medicine
Ulyana Muñoz Acuña, Shunyan Mo, Jiachen Zi, Jimmy Orjala, Esperanza J Carcache DE Blanco
BACKGROUND: Prostate cancer presents the highest incidence rates among all cancers in men. Hapalindole H (Hap H), isolated from Fischerella muscicola (UTEX strain number LB1829) as part of our natural product anticancer drug discovery program, was found to be significantly active against prostate cancer cells. MATERIALS AND METHODS: In this study, Hap H was tested for nuclear factor-kappa B (NF-ĸB) inhibition and selective cytotoxic activity against different cancer cell lines...
June 2018: Anticancer Research
Paulino José García Nieto, Esperanza García-Gonzalo, Fernando Sánchez Lasheras, José Ramón Alonso Fernández, Cristina Díaz Muñiz, Francisco Javier de Cos Juez
Cyanotoxins are a type of cyanobacteria that is poisonous and poses a health threat in waters that could be used for drinking or recreational purposes. Thus, it is necessary to predict their presence to avoid risks. This paper presents a nonparametric machine learning approach using a gradient boosted regression tree model (GBRT) for prediction of cyanotoxin contents from cyanobacterial concentrations determined experimentally in a reservoir located in the north of Spain. GBRT models seek and obtain good predictions in highly nonlinear problems, like the one treated here, where the studied variable presents low concentrations of cyanotoxins mixed with high concentration peaks...
May 30, 2018: Environmental Science and Pollution Research International
Aurora Romar-Gasalla, Vanesa Santás-Miguel, Juan Carlos Nóvoa-Muñoz, Manuel Arias-Estévez, Esperanza Álvarez-Rodríguez, Avelino Núñez-Delgado, María J Fernández-Sanjurjo
Using batch-type experiments, chromium (Cr(VI)) and fluoride (F- ) sorption/desorption were studied in forest and vineyard soil samples, pyritic material, pine bark, oak ash, hemp waste and mussel shell, as well as on samples of forest and vineyard soil, and of pyritic material, individually treated with 48 t ha-1 of pine bark, oak ash, and mussel shell. Pine bark showed the highest Cr(VI) sorption (always > 97% of the concentration added) and low desorption (<1.5%). Pyritic material sorbed between 55 and 98%, and desorbed between 0...
May 22, 2018: Journal of Environmental Management
Carlos Gutiérrez-López-Franca, Ramón Hervás, Esperanza Johnson
This paper aims to improve activity recognition systems based on skeletal tracking through the study of two different strategies (and its combination): (a) specialized body parts analysis and (b) stricter restrictions for the most easily detectable activities. The study was performed using the Extended Body-Angles Algorithm , which is able to analyze activities using only a single key sample. This system allows to select, for each considered activity, which are its relevant joints , which makes it possible to monitor the body of the user selecting only a subset of the same...
May 22, 2018: Sensors
Esperanza Torres, Inge N Pedersen, José I Pérez-Fernández
Background: Fibromyalgia (FM) affects about 2-4% of the world population. Patients, mostly women, experience chronic widespread pain, fatigue, stiffness, sleep disturbances, and psychological disorders, especially depression and anxiety. Objective: The aim of this study was to examine preliminary efficacy of a Group Music and Imagery (GrpMI) intervention, which included relaxation, music listening, and spontaneous imagery, to improve subjective psychological well-being, functional capacity and health, pain perception, anxiety, and depression in women with FM...
May 18, 2018: Journal of Music Therapy
Esperanza Rivera-de-Torre, Álvaro Martínez-Del-Pozo, Jessica E Garb
Transcriptomic profiling of venom producing tissues from different animals is an effective approach for discovering new toxins useful in biotechnological and pharmaceutical applications, as well in evolutionary comparative studies of venomous animals. Stichodactyla helianthus is a Caribbean sea anemone which produces actinoporins as part of its toxic venom. This family of pore forming toxins is multigenic and at least two different isoforms, encoded by separate genes, are produced by S. helianthus. These isoforms, sticholysins I and II, share 93% amino acid identity but differ in their pore forming activity and act synergistically...
May 19, 2018: Toxicon: Official Journal of the International Society on Toxinology
Jesús Vaquero, Mercedes Zurita, Miguel A Rico, Concepcion Aguayo, Cecilia Fernandez, Gregorio Rodriguez-Boto, Esperanza Marin, Noemi Tapiador, Marta Sevilla, Joaquin Carballido, David Vazquez, Damian Garcia-Olmo, Hector Guadalajara, Miguel Leon, Ignacio Valverde
BACKGROUND AIMS: Recently, clinical studies show that cell therapy with mesenchymal stromal cells (MSCs) improves the sequelae chronically established in paraplegic patients, being necessary to know which of them can obtain better benefit. METHODS: We present here a phase 2 clinical trial that includes six paraplegic patients with post-traumatic syringomyelia who received 300 million MSCs inside the syrinx and who were followed up for 6 months. Clinical scales, urodynamic, neurophysiological, magnetic resonance (MR) and studies of ano-rectal manometry were performed to assess possible improvements...
May 18, 2018: Cytotherapy
Javier Muriel, César Margarit, Beatriz Planelles, María J Serralta, Carmen Puga, María-Del-Mar Inda, Esperanza Cutillas, Domingo Morales, José F Horga, Ana M Peiró
Screening for opioid use disorder should be considered in chronic non-cancer pain (CNCP) patients with long-term use of opioids. The aim of our study was to assess the effectiveness of an individualized treatment plan (ITP) for prescription opioid dependence that included screening of pharmacogenetic markers. An observational prospective study was performed using prescription opioid-dependent CNCP outpatients (n = 88). Patients were divided into nonresponders, responders, or high responders according to their response to the ITP...
May 20, 2018: Annals of the New York Academy of Sciences
Nathalie Michels, Gerard Clarke, Loreto Olavarria-Ramirez, Sonia Gómez-Martínez, Ligia Esperanza Díaz, Ascensión Marcos, Kurt Widhalm, Livia A Carvalho
BACKGROUND: Tryptophan breakdown is an important mechanism in several diseases e.g. inflammation and stress-induced inflammation have been associated with the development of depression via enhanced tryptophan breakdown. Depression is a major public health problem which commonly starts during adolescence, thus identifying underlying mechanisms during early life is crucial in prevention. The aim of this work was to verify whether independent and interacting associations of psychosocial stress and inflammation on tryptophan breakdown already exist in children and adolescents as a vulnerable age group...
May 15, 2018: Psychoneuroendocrinology
Angella López-Cedeño, Gustavo Cañedo, Nicole Knöpfel, Isabel Colmenero, Esperanza Pérez-Pastrana, Antonio Torrelo
The case of a 6-year-old boy with multiple, target-shaped lesions and a crusted nodule on his right index finger is presented. Based on clinical findings and the patient's recent contact with sheep and goats, a diagnosis of orf disease associated with erythema multiforme was suspected. Microscopy studies confirmed the presence of parapoxvirus in the primary lesion. Orf-induced erythema multiforme is a rare complication of orf in children, possibly related to the presence of orf virus DNA in erythema multiforme lesions...
May 15, 2018: Pediatric Dermatology
Carmen Moret-Tatay, Daniel Gamermann, Esperanza Navarro-Pardo, Pedro Fernández de Córdoba Castellá
The study of reaction times and their underlying cognitive processes is an important field in Psychology. Reaction times are often modeled through the ex-Gaussian distribution, because it provides a good fit to multiple empirical data. The complexity of this distribution makes the use of computational tools an essential element. Therefore, there is a strong need for efficient and versatile computational tools for the research in this area. In this manuscript we discuss some mathematical details of the ex-Gaussian distribution and apply the ExGUtils package, a set of functions and numerical tools, programmed for python, developed for numerical analysis of data involving the ex-Gaussian probability density...
2018: Frontiers in Psychology
Billy Bromage, John A Encandela, Melissa Cranford, Esperanza Diaz, Bridgett Williamson, Virginia T Spell, Robert M Rohrbaugh
No abstract text is available yet for this article.
May 14, 2018: Academic Psychiatry
Marc Clos-Garcia, Ana Loizaga-Iriarte, Patricia Zuñiga-Garcia, Pilar Sánchez-Mosquera, Ana Rosa Cortazar, Esperanza González, Verónica Torrano, Cristina Alonso, Miriam Pérez-Cormenzana, Aitziber Ugalde-Olano, Isabel Lacasa-Viscasillas, Azucena Castro, Felix Royo, Miguel Unda, Arkaitz Carracedo, Juan M Falcón-Pérez
Urine contains extracellular vesicles (EVs) that concentrate molecules and protect them from degradation. Thus, isolation and characterisation of urinary EVs could increase the efficiency of biomarker discovery. We have previously identified proteins and RNAs with differential abundance in urinary EVs from prostate cancer (PCa) patients compared to benign prostate hyperplasia (BPH). Here, we focused on the analysis of the metabolites contained in urinary EVs collected from patients with PCa and BPH. Targeted metabolomics analysis of EVs was performed by ultra-high-performance liquid chromatography-mass spectrometry...
2018: Journal of Extracellular Vesicles
Aurora Romar-Gasalla, Juan Carlos Nóvoa-Muñoz, Manuel Arias-Estévez, María J Fernández-Sanjurjo, Esperanza Álvarez-Rodríguez, Avelino Núñez-Delgado
Batch experiments were used to test P sorbent potential of soil samples, pyritic and granitic materials, mussel shell, mussel shell ash, sawdust, and slate waste fines for different pH and incubation times. Maximum P sorption varied in a wide range of pH: < 4 for pyritic material, 4-6 for forest soil, > 5 for slate fines, > 6 for shell ash, and pH 6-8 for mussel shell. P sorption was rapid (< 24 h) for forest soil, shell ash, pyritic material, and fine shell. On the opposite side, it was clearly slower for vineyard soil, granitic material, slate fines, pine sawdust, and coarse shell, with increased P sorption even 1 month later...
May 13, 2018: Environmental Science and Pollution Research International
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