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https://www.readbyqxmd.com/read/29764569/-combined-effect-of-gestational-age-and-birth-weight-on-metabolites-related-to-inherited-metabolic-diseases-in-neonates
#1
Fang Yi, Ling Wang, Mei Wang, Xue-Lian Yuan, Hua-Jing Wan, Jia-Yuan Li
OBJECTIVE: To study the combined effect of gestational age and birth weight on metabolites related to inherited metabolic diseases (IMD). METHODS: A total of 3 381 samples ruled out of IMD by follow-up were randomly selected from 38 931 newborns who participated in the neonatal IMD screening during 2014-2016. The 3 381 neonates were categorized into seven groups according to their gestational age and birth weight: extremely preterm appropriate-for-gestational age (AGA) group (n=12), preterm small-for-gestational age (SGA) group (n=18), preterm AGA group (n=219), preterm large-for-gestational age (LGA) group (n=18), full-term SGA group (n=206), full-term AGA group (n=2 677), and full-term LGA group (n=231)...
May 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29764503/bacteriological-profile-of-neonatal-sepsis-and-antibiotic-susceptibility-pattern-of-isolates-admitted-at-kanti-children-s-hospital-kathmandu-nepal
#2
Nikita Singh Yadav, Saroj Sharma, Dhiraj Kumar Chaudhary, Prabhat Panthi, Pankaj Pokhrel, Anil Shrestha, Pappu Kumar Mandal
OBJECTIVE: Neonatal sepsis is a major cause of morbidity and mortality of newborns (< 1 month of age). Septicemia and drug resistance is a predominant issue for neonatal death in Nepal. This study is intended to find bacteriological profile of neonatal sepsis and antibiotic susceptibility pattern of the isolates from neonates at Kanti Children's Hospital, Kathmandu, Nepal. RESULTS: Out of 350 suspected cases of neonatal sepsis, 59 (16.9%) cases showed positive blood culture...
May 15, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29762472/weaning-time-in-preterm-infants-an-audit-of-italian-primary-care-paediatricians
#3
Maria Elisabetta Baldassarre, Antonio Di Mauro, Annarita Pedico, Valentina Rizzo, Manuela Capozza, Fabio Meneghin, Gianluca Lista, Nicola Laforgia
INTRODUCTION: According to the 2016 Italian National Institute of Statistics (Istat) data in Italy, about 6.7% of all newborns are born prematurely. Due to the lack of data on current complementary feeding in preterm infants in Italy, the aim of the survey was to evaluate individual attitudes of primary care paediatricians, concerning the introduction of complementary foods in preterm infants. METHODS: An internet-based survey was conducted among primary care paediatricians, working in Italy, regarding (1) timing of the introduction of complementary foods to preterm newborns; (2) type of complementary foods introduced; (3) vitamin D and iron supplementations...
May 15, 2018: Nutrients
https://www.readbyqxmd.com/read/29754448/periodontal-infection-with-porphyromonas-gingivalis-induces-preterm-birth-and-lower-birth-weight-in-rats
#4
Shanshan Liang, Hongyu Ren, Haiying Guo, Wenyan Xing, Chang Liu, Yaoting Ji, Han Jiang, Ping Zhang, Minquan Du
Preterm birth (PTB), accompanied by low birth weight (LBW) or not, is a syndrome with tremendous risk factors and long-term health consequences for children. In recent decades, overwhelming studies have shown that periodontitis contributes to prematurity and LBW. This study was conducted to determine the link between maternal periodontitis and the pathogenesis of PTB and/or LBW through a rat infection model induced by Porphyromonas gingivalis, an important periodontopathic bacterium. The murine model was established by surgically ligating the left mandibular 1st molars and inoculating with P...
May 13, 2018: Molecular Oral Microbiology
https://www.readbyqxmd.com/read/29750954/neonatal-and-fetal-growth-charts-to-identify-preterm-infants-less-than-30-weeks-gestation-at-risk-of-adverse-outcomes
#5
Nansi S Boghossian, Marco Geraci, Erika M Edwards, Jeffrey D Horbar
BACKGROUND: It is unclear whether a neonatal or a fetal growth standard is a better predictor of adverse in-hospital newborn outcomes. OBJECTIVE: We aimed to evaluate and compare the power of birth weight for gestational age to predict adverse neonatal outcomes using neonatal and fetal growth charts. Gestational age specific birth weight was examined either as a centile score or as a binary indicator for birth weight below the 10th centile (small for gestational age) using three fetal growth charts (National Institute of Child Health and Human Development, World Health Organization, and Intergrowth-21st ) and one neonatal sex-specific birth weight chart...
May 8, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29747664/adverse-effects-in-children-exposed-to-maternal-hiv-and-antiretroviral-therapy-during-pregnancy-in-brazil-a-cohort-study
#6
Adriane M Delicio, Giuliane J Lajos, Eliana Amaral, Fernanda Cavichiolli, Marina Polydoro, Helaine Milanez
BACKGROUND: Antiretroviral therapy (ART) in pregnancy was associated with a drastic reduction in HIV mother-to-child transmission (MTCT), although it was associated with neonatal adverse effects. The aim of this study was to evaluate the neonatal effects to maternal ART. METHODS: This study was a cohort of newborns from HIV pregnant women followed at the CAISM/UNICAMP Obstetric Clinic from 2000 to 2015. The following adverse effects were evaluated: anemia, thrombocytopenia, liver function tests abnormalities, preterm birth, low birth weight and congenital malformation...
May 10, 2018: Reproductive Health
https://www.readbyqxmd.com/read/29744744/anterior-fontanelle-size-in-healthy-indian-late-preterm-and-full-term-newborns
#7
Shuvendu Roy, Vishal Vishnu Tewari, Jawede Equbal
OBJECTIVE: To measure the size of the anterior fontanelle (AF) in healthy late-preterm and term newborns and correlate it with birth weight, gestational age, gender, occipito-frontal circumference, small for gestational age status and birth weight z-score. METHODS: This was an observational study carried out from October 2013 through April 2015 at a tertiary care hospital. Newborns ≥ 34 wk gestation were enrolled. Fontanelle edge was palpated with index finger and size calculated by adding anterior-posterior and transverse diameters and dividing by two...
May 9, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29743085/determinants-of-early-neonatal-mortality-in-afghanistan-an-analysis-of-the-demographic-and-health-survey-2015
#8
Gulam Muhammed Al Kibria, Vanessa Burrowes, Allysha Choudhury, Atia Sharmeen, Swagata Ghosh, Arif Mahmud, Angela Kc
BACKGROUND: Neonatal mortality is declining slowly compared to under-five mortality in many developing countries including Afghanistan. About three-fourths of these deaths occur in the early neonatal period (i.e., the first week of life). Although a number of studies investigated determinants of early neonatal mortality in other countries, there is a lack of evidence regarding this in Afghanistan. This study investigated determinants of early neonatal mortality in Afghanistan. METHODS: Data from the Afghanistan Demographic and Health Survey 2015 (AfDHS 2015) were analyzed...
May 9, 2018: Globalization and Health
https://www.readbyqxmd.com/read/29725376/low-dose-aspirin-at-%C3%A2-16-weeks-of-gestation-for-preventing-preeclampsia-and-its-maternal-and-neonatal-adverse-outcomes-a-systematic-review-and-meta-analysis
#9
Yuechong Cui, Bin Zhu, Fei Zheng
The aim of the present meta-analysis study was to evaluate the efficacy of low-dose aspirin, commenced at ≤16 weeks of gestation, in preventing preterm and term preeclampsia, as well as associated maternal and neonatal adverse events in women at risk of preeclampsia. The Embase, PubMed, Cochrane Central Register of Controlled Trials and the Web of Science databases were searched for relevant random controlled trials (RCTs) published between January 1979 and October 2017. After quality assessment and data extraction, a meta-analysis was performed using RevMan 5...
May 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29715698/antenatal-vitamin-d-preserves-placental-vascular-and-fetal-growth-in-experimental-chorioamnionitis-due-to-intra-amniotic-endotoxin-exposure
#10
Michael W Cookson, Sharon L Ryan, Gregory J Seedorf, R Blair Dodson, Steve H Abman, Erica W Mandell
BACKGROUND:  Chorioamnionitis (CA) is associated with a high risk for the development of bronchopulmonary dysplasia (BPD) after preterm birth, but mechanisms that increase susceptibility for BPD and strategies to prevent BPD are uncertain. As a model of CA, antenatal intra-amniotic (IA) endotoxin (ETX) exposure alters placental structure, causes fetal growth restriction, increases perinatal mortality, and causes sustained cardiorespiratory abnormalities throughout infancy. Vitamin D (Vit D) has been shown to have both anti-inflammatory and proangiogenic properties...
May 1, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29715567/bronchopulmonary-dysplasia-predictor-scale-validation-in-preterm-newborns-in-two-neonatal-units-at-2600-m-above-sea-level
#11
Pablo Vasquez, Hector Alfonso Romero Diaz, Maria Juanita Gomez Gomez, Lida Leal, Lorena Margarita Yejas Navarro
INTRODUCTION: Bronchopulmonary dysplasia (BPD) is common in premature babies. It is difficult to predict the risk of developing this disease and its definition is not well characterized in high altitude cities. OBJECTIVE: To determine the operating characteristics of a BPD predictive scale for in preterm infants based on a classical BPD definition and one adjusted for altitude. MATERIALS AND METHOD: Observational, analytical, longitudinal study with infants gestational age ≤32 weeks admitted at two University Hospital's in the city of Bogotá, Colombia between June 2010 and December 2016...
April 28, 2018: Infant Behavior & Development
https://www.readbyqxmd.com/read/29715193/severe-lactic-acidosis-in-an-extremely-low-birth-weight-infant-due-to-thiamine-deficiency
#12
Hulya Ozdemir, Hulya Bilgen, Zeynep Alp Unkar, Ertugrul Kiykim, Asli Memisoglu, Eren Ozek
BACKGROUND: In this case report, we present a preterm newborn with persistent lactic acidosis who received total parenteral nutrition (TPN) that lacked thiamine. CASE PRESENTATION: A 28-week-old, 750 g female infant was born with an Apgar score of 8 at the 5th minute. Umbilical cord blood gas levels, including lactate level, were normal, and she was admitted to our neonatal intensive care unit (NICU). Achieving full enteral feeding was not possible due to gastric residues and abdominal distention, making the patient dependent on TPN during the first 2 weeks of life...
May 1, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29689751/effect-of-standardized-feeding-protocol-on-nutrient-supply-and-postnatal-growth-of-preterm-infants-a-prospective-study
#13
Z Khan, N Morris, H Unterrainer, N Haiden, S J Holasek, B Urlesberger
BACKGROUND: Preterm birth is a medical emergency and it is becoming evident that adequate nutrition starting in the first hours of life is of major importance for short and even more so for long-term health outcomes of the premature newborn. The aim was to analyze postnatal nutrient supply and growth patterns of preterm infants in response to a standardized feeding protocol during stay at neonatal intensive care unit (NICU). METHODS: A prospective cohort study was conducted at NICU, Children Hospital Graz...
2018: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/29689749/the-association-between-alcohol-outlet-accessibility-and-adverse-birth-outcomes-a-retrospective-cohort-study
#14
J A Seabrook, N Woods, A Clark, B de Vrijer, D Penava, J Gilliland
BACKGROUND: Alcohol outlet accessibility is positively associated with alcohol consumption, although this relationship has not been thoroughly examined in pregnant women. The present study examines the relationship between proximity and density of alcohol outlets and risk for low birth weight (LBW: <2,500 grams) and preterm birth (PTB: <37 weeks gestational age), and is the first Canadian study to investigate this association. METHODS: Maternal accessibility to alcohol outlets was specified using a gravity-type measure of accessibility, which provides the amount of accessibility that a given household has to liquor stores within 30-minutes of their home...
2018: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/29689020/factors-that-influence-human-milk-feeding-at-hospital-discharge-for-preterm-infants-in-a-tertiary-neonatal-care-center-in-taiwan
#15
Chia-Ming Pai, Wai-Tim Jim, Hsiang-Yu Lin, Chyong-Hsin Hsu, Hsin-An Kao, Han-Yang Hung, Chun-Chih Peng, Jui-Hsing Chang
Human milk is considered optimal nutrition for newborn infants, especially preterm infants, and it can lessen morbidity in this population. Human milk feeding at hospital discharge may encourage breastfeeding at home. This study evaluated the incidence and predictive factors of human milk feeding of preterm infants at discharge. It included all preterm infants with gestational age of less than 37 weeks who were admitted to the Mackay Memorial Hospital in Taiwan from January to December 2010 who survived to discharge...
April 2018: Journal of Perinatal & Neonatal Nursing
https://www.readbyqxmd.com/read/29676033/fio-2-control-by-parents-of-preterm-infants-admitted-to-a-neonatal-intensive-care-unit-a-pilot-study
#16
M D Martín-Pelegrina, A Lorenzo-Rodríguez, D Lora-Pablos, B Muñóz-Amat, C Morales-Betancourt, C R Pallás-Alonso
When newborns are admitted to the neonatal intensive care unit for prematurity or other reasons, parents do not take on the role that they were expecting to assume. That is, they do not become the main caregivers of their children. To address this issue, neonatal units are currently trying to involve parents in the care of their children as soon as possible. Interesting experiences regarding this issue have been published. Most of the experiences show that when parents assume part of the responsibility for caring for their children, breastfeeding is prolonged, hospital-stay lengths decrease, weight gain increases and the numbers of readmissions decrease (1-4)...
April 19, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29662257/17-hydroxiprogesterone-values-in-healthy-preterm-infants
#17
Víctor Clemente Mendoza-Rojas, Luis Alfonso Díaz-Martínez, Gerardo Mantilla-Mora, Gustavo Adolfo Contreras-García, Víctor Manuel Mora-Bautista, Jhon Freddy Martínez-Paredes, Alba Luz Calderón-Rojas, Carlos Augusto Gómez-Tarazona, Katherine Pinzón-Mantilla
Introduction: In preterm newborn, problems with the interpretation of 17-OHP may occur. Objective: Evaluate 17-OHP values in healthy preterm newborns until they reach the corrected gestational age. Methods: Longitudinal study of 36 preterm infants with 17-OHP evaluation using ELISA from heel blood from 3 to 5 days and thereafter every 2 weeks until the corrected gestational age. Values adjusting multiple variables such as gestational age, birth weight and sex, among others were compared...
December 30, 2017: Colombia Médica: CM
https://www.readbyqxmd.com/read/29650428/-extrauterine-growth-restriction-among-neonates-with-a-birthweight-less-than-1-500grams
#18
Alejandro Avila-Alvarez, Alfonso Solar Boga, Carmen Bermúdez-Hormigo, Jesús Fuentes Carballal
INTRODUCTION: Growth restriction in preterm infants has been related to a poor neurodevelopment outcome. OBJECTIVES: To define the incidence of postnatal growth restriction in premature babies ≤1,500 grams and to detect related clinical or biochemical markers. METHODS: Retrospective longitudinal observational study. Multivariate linear regression models were used to determine variables that can predict the change in weight z-score during admission...
April 9, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29642740/maternal-periodontal-disease-and-adverse-perinatal-outcomes-is-there-an-association-a-hospital-based-case-control-study
#19
Marta Silveira da Mota Krüger, Renata Picanço Casarin, Gabriela Dos Santos Pinto, Fernanda Geraldo Pappen, Maria Beatriz Junqueira Camargo, Fernanda Oliveira Bello Correa, Ana Regina Romano
OBJECTIVES: The association between maternal periodontal disease and adverse perinatal outcomes although extensively studied remains unclear. The aim of this study was to evaluate, by a case-control study, conducted in three hospitals the association between preterm birth and/or low birth weight (PTB/LBW) and clinical parameters of maternal periodontal disease. MATERIAL AND METHODS: Postpartum women who gave birth to a newborn PTB/LBW (case group), and postpartum women who had babies at full term with normal weight (control group) were included, in 1:2 ratio...
April 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29624206/paracetamol-acetaminophen-for-patent-ductus-arteriosus-in-preterm-or-low-birth-weight-infants
#20
REVIEW
Arne Ohlsson, Prakeshkumar S Shah
BACKGROUND: In preterm newborns, the ductus arteriosus frequently fails to close and the infants require medical or surgical closure of the patent ductus arteriosus (PDA). A PDA can be treated surgically; or medically with one of two prostaglandin inhibitors, indomethacin or ibuprofen. Case reports suggest that paracetamol may be an alternative for the closure of a PDA. An association between prenatal or postnatal exposure to paracetamol and later development of autism or autism spectrum disorder has been reported...
April 6, 2018: Cochrane Database of Systematic Reviews
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