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https://www.readbyqxmd.com/read/28532720/the-dietary-composition-of-women-who-delivered-preterm-and-full-term-infants
#1
Wioletta Waksmańska, Rafał Bobiński, Izabela Ulman-Włodarz, Anna Pielesz, Monika Mikulska
OBJECTIVES: Literature data show that excess and primary deficiency in particular nutrients, vitamins and minerals may lead to pre-eclampsia, gestational diabetes, hypertension and neural tube defects in the foetus. The aim of the study was to determine differences in average daily consumption of selected nutrients during pregnancy in women who did not supplement their diet and to evaluate the influence of dietary habits on the occurrence of pre-term delivery and hypertension in pregnant women...
June 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/28526224/neurocognitive-outcomes-at-10-years-of-age-in-extremely-preterm-newborns-with-late-onset-bacteremia
#2
H Reeve Bright, Kikelomo Babata, Elizabeth N Allred, Carmina Erdei, Karl C K Kuban, Robert M Joseph, T Michael O'Shea, Alan Leviton, Olaf Dammann
OBJECTIVE: To evaluate the difference in 10-year neurocognitive outcomes between extremely low gestational age newborns without bacteremia and those with suspected or confirmed late-onset bacteremia. STUDY DESIGN: Neurocognitive function was evaluated at 10 years of age in 889 children born at <28 weeks of gestation and followed from birth. Definite (culture-positive) late-onset bacteremia during postnatal weeks 2-4 was identified in 223 children, and 129 children had suspected bacteremia...
May 16, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28520902/early-acquisition-of-pneumocystis-jirovecii-colonization-and-potential-association-with-respiratory-distress-syndrome-in-preterm-newborn-infants
#3
Pilar Rojas, Vicente Friaza, Elisa Garcia, Carmen de la Horra, Sergio L Vargas, Enrique J Calderón, Antonio Pavón
Background: Pneumocystis pneumonia is a well-recognized lung disease of premature and malnourished babies. Even though, serologic studies have shown that children are exposed to Pneumocystis jirovecii early in life the epidemiology of human P. jirovecii infection and the host-microorganism relationship in infancy remain poorly understood. The aim of the present study was to investigate the prevalence of P. jirovecii colonization in preterm infants and its possible association with medical complications...
May 17, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28506869/model-based-clinical-dose-optimization-for-phenobarbital-in-neonates-an-illustration-of-the-importance-of-data-sharing-and-external-validation
#4
Swantje Völler, Robert B Flint, Leo M Stolk, Pieter L J Degraeuwe, Sinno H P Simons, Paula Pokorna, David M Burger, Ronald de Groot, Dick Tibboel, Catherijne A J Knibbe
BACKGROUND: Particularly in the pediatric clinical pharmacology field, data-sharing offers the possibility of making the most of all available data. In this study, we utilize previously collected therapeutic drug monitoring (TDM) data of term and preterm newborns to develop a population pharmacokinetic model for phenobarbital. We externally validate the model using prospective phenobarbital data from an ongoing pharmacokinetic study in preterm neonates. METHODS: TDM data from 53 neonates (gestational age (GA): 37 (24-42) weeks, bodyweight: 2...
May 12, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28501874/screening-tool-for-early-postnatal-prediction-of-retinopathy-of-prematurity-in-preterm-newborns-step-rop
#5
Caroline A Ricard, Christiane E L Dammann, Olaf Dammann
BACKGROUND: Retinopathy of prematurity (ROP) is a disorder of the preterm newborn characterized by neurovascular disruption in the immature retina that may cause visual impairment and blindness. OBJECTIVE: To develop a clinical screening tool for early postnatal prediction of ROP in preterm newborns based on risk information available within the first 48 h of postnatal life. METHODS: Using data submitted to the Vermont Oxford Network (VON) between 1995 and 2015, we created logistic regression models based on infants born <28 completed weeks gestational age...
May 13, 2017: Neonatology
https://www.readbyqxmd.com/read/28490415/maternal-and-perinatal-characteristics-of-small-for-gestational-age-newborns-ten-year-experience-of-a-single-center
#6
Nihal Şahin Uysal, Çağrı Gülümser, Filiz Bilgin Yanık
OBJECTIVE: The aim of this study was to analyze the maternal and perinatal characteristics of small for gestational age (SGA) newborns compared to appropriate for gestational age (AGA) newborns in singleton pregnancies managed at our hospital between January 2006 and December 2015. MATERIAL AND METHODS: The study (n=456) and control (n=4925) groups included pregnancies resulting in SGA and AGA newborns, respectively. Additionally, two SGA subgroups were defined according to abnormal (n=34) and normal (n=57) Doppler findings...
May 11, 2017: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/28489558/evaluation-of-factors-associated-with-elevated-newborn-17-hydroxyprogesterone-levels
#7
V Shobi Anandi, Bhattacharyya Shaila
BACKGROUND: Measurement of 17-hydroxyprogesterone (17-OHP) in dried blood spots has been widely used as a newborn screening tool for congenital adrenal hyperplasia (CAH). Various maternal and neonatal factors can result in falsely high values of 17-OHP. There is a paucity of Indian studies in this regard because routine evaluation of newborn 17-OHP levels as a screening program is not widely practiced in India. Hence, this study was undertaken to evaluate the influence of various maternal and neonatal factors on newborn 17-OHP levels...
May 10, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28488361/clonidine-for-sedation-and-analgesia-for-neonates-receiving-mechanical-ventilation
#8
REVIEW
Olga Romantsik, Maria Grazia Calevo, Elisabeth Norman, Matteo Bruschettini
BACKGROUND: Although routine administration of pharmacologic sedation or analgesia during mechanical ventilation in preterm neonates is not recommended, its use in clinical practice remains common. Alpha-2 agonists, mainly clonidine and dexmedetomidine, are used as adjunctive (or alternative) sedative agents alongside opioids and benzodiazepines. Clonidine has not been systematically assessed for use in neonatal sedation during ventilation. OBJECTIVES: To assess whether clonidine administered to term and preterm newborn infants receiving mechanical ventilation reduces morbidity and mortality rates...
May 10, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28449646/when-is-the-use-of-pacifiers-justifiable-in-the-baby-friendly-hospital-initiative-context-a-clinician-s-guide
#9
Welma Lubbe, Wilma Ten Ham-Baloyi
BACKGROUND: The use of pacifiers is an ancient practice, but often becomes a point of debate when parents and professionals aim to protect and promote breastfeeding as most appropriately for nurturing infants. We discuss the current literature available on pacifier use to enable critical decision-making regarding justifiable use of pacifiers, especially in the Baby-Friendly Hospital Initiative context, and we provide practical guidelines for clinicians. DISCUSSION: Suck-swallow-breathe coordination is an important skill that every newborn must acquire for feeding success...
April 27, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28445454/body-composition-at-birth-and-its-relationship-with-neonatal-anthropometric-ratios-the-newborn-body-composition-study-of-the-intergrowth-21st-project
#10
José Villar, Fabien A Puglia, Tanis R Fenton, L Cheikh Ismail, Eleonora Staines-Urias, Francesca Giuliani, Eric O Ohuma, Cesar G Victora, Peter Sullivan, Fernando C Barros, Ann Lambert, Aris T Papageorghiou, Roseline Ochieng, Yasmin A Jaffer, Douglas G Altman, Alison J Noble, Michael G Gravett, Manorama Purwar, Ruyan Pang, Ricardo Uauy, Stephen H Kennedy, Zulfiqar A Bhutta
BACKGROUND: We aimed to describe newborn body composition and identify which anthropometric ratio (weight/length; BMI; or ponderal index, PI) best predicts fat mass (FM) and fat-free mass (FFM). METHODS: Air-displacement plethysmography (PEA POD) was used to estimate FM, FFM and body fat percentage (BF%). Associations between FFM, FM and BF% and weight/length, BMI and PI were evaluated in 1,019 newborns using multivariate regression analysis. Charts for FM, FFM and BF% were generated using a prescriptive sub-sample (n=247)...
April 26, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28444286/screening-for-preeclampsia-us-preventive-services-task-force-recommendation-statement
#11
Kirsten Bibbins-Domingo, David C Grossman, Susan J Curry, Michael J Barry, Karina W Davidson, Chyke A Doubeni, John W Epling, Alex R Kemper, Alex H Krist, Ann E Kurth, C Seth Landefeld, Carol M Mangione, William R Phillips, Maureen G Phipps, Michael Silverstein, Melissa A Simon, Chien-Wen Tseng
Importance: Preeclampsia affects approximately 4% of pregnancies in the United States. It is the second leading cause of maternal mortality worldwide and may lead to serious maternal complications, including stroke, eclampsia, and organ failure. Adverse perinatal outcomes for the fetus and newborn include intrauterine growth restriction, low birth weight, and stillbirth. Many of the complications associated with preeclampsia lead to early induction of labor or cesarean delivery and subsequent preterm birth...
April 25, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28441153/discharge-criteria-for-the-late-preterm-infant-a-review-of-the-literature
#12
Jenny M Quinn, Marteen Sparks, Sheila M Gephart
BACKGROUND: Standardized late preterm infant (LPI) discharge criteria ensure best practice and help guide the neonatal provider to determine the appropriate level of care following birth. However, the location can vary from the well newborn setting to the neonatal intensive care unit (NICU). PURPOSE: The purpose of this review is to examine differences in LPI discharge criteria between the well newborn setting and the NICU by answering the clinical questions, "What are the recommended discharge criteria for the LPI and do they differ if admitted to the well newborn setting versus the NICU?" SEARCH STRATEGY: Databases searched include CINAHL, TRIP, PubMed, and the Cochrane Library...
April 24, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28440869/massive-pleural-effusion-on-the-contralateral-side-of-a-venous-peripherally-inserted-central-catheter
#13
Selim Sancak, Abdulhamit Tuten, Tulin Gokmen Yildirim, Guner Karatekin
A preterm newborn infant, delivered at 30 weeks of gestation and 965 g birth weight, developed respiratory distress with resistant hypoxia after a central catheter line was inserted via the right venae brachialis on postnatal day 21. Left-sided massive pleural effusion, collapsed left lung with air bronchograms, and bidirectional shunting through reopened ductus arteriosus were detected by targeted neonatal echocardiography. Hydrothorax was drained under sonographic guidance, producing a milky-white fluid biochemically compatible with parenteral nutrition...
April 25, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28436200/randomised-controlled-trial-shows-that-co-bedding-twins-may-reduce-birth-weight-recovery-delay-parenteral-nutrition-weaning-time-and-hospitalisation
#14
Arnaud Legrand, Anne Frondas, Fabien Aubret, Anne Corre, Cyril Flamant, Laure Simon, Clothilde Desrobert, Jean-Christophe Rozé
AIM: Cobedding describes a technique where premature twins are kept within the same incubator, inside a common cocoon, to prolong the alleged in utero behavioral bond and reduce post-natal stress. However there is no consensus amongst neonatologists regarding any clinical or developmental benefits cobedding may provide, in particular when performed early after the birth. The NEOCOB (NEOnatology & COBedding) trial aimed to assess, for the first time, early cobedding in preterm newborn twins...
April 24, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28419552/feasibility-and-utility-of-portable-ultrasound-during-retrieval-of-sick-preterm-infants
#15
Kathryn Browning Carmo, Tracey Lutz, Mark Greenhalgh, Andrew Berry, Martin Kluckow, Nick Evans
AIM: Document the incidence of haemodynamic pathology in critically ill preterm newborns requiring transport. METHOD: A transport neonatologist performed cardiac and cerebral ultrasound before and after transportation of infants born ≤ 30 weeks gestation. RESULTS: 44 newborns were studied 2008 - 2015, 21 transported by road, 19 by helicopter and 4 by fixed wing. Median birth weight 1130g (680-1960g), median gestation 27 weeks (23-30) and 30/44 were male...
April 17, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28412958/supporting-parents-in-taking-care-of-their-infants-admitted-to-a-neonatal-intensive-care-unit-a-prospective-cohort-pilot-study
#16
Giuseppe De Bernardo, Maria Svelto, Maurizio Giordano, Desiree Sordino, Marina Riccitelli
BACKGROUND: Family-Centred Care (FCC) is recognized as an important component of all paediatric care, including neonatal care, although practical clinical guidelines to support this care model are still needed in Italy. The characteristics and services for families in Italian NICUs show a lack of organization and participation. METHODS: The first aim was to compare satisfaction and stress levels in two groups of parents: an FCC group and a non-FCC group (NFCC). The second aim was to evaluate body weight gain in the newborns enrolled...
April 17, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28409493/obesity-in-pregnancy-a-novel-concept-on-the-roles-of-adipokines-in-uterine-contractility
#17
REVIEW
Judit Hajagos-Tóth, Eszter Ducza, Reza Samavati, Sandor G Vari, Robert Gaspar
Obesity is a global health problem even among pregnant women. Obesity alters quality of labor, such as preterm labor, prolonged labor, and higher oxytocin requirements in pregnant women. The most important factors to play a role in the altered gestational period and serve as drug targets to treat the consequences are female sexual hormones, calcium channels, adrenergic system, oxytocin, and prostaglandins. However, we have limited information about the impact of obesity on the pregnant uterine contractility and gestation time...
April 14, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/28397036/risk-factors-for-low-birth-weight-and-preterm-birth-a-population-based-case-control-study-in-wuhan-china
#18
Jing Wang, Yun Zeng, Ze-Min Ni, Gui Wang, Shu-Yun Liu, Can Li, Chao-Li Yu, Qi Wang, Shao-Fa Nie
Low birth weight (LBW) and preterm birth (PB) are associated with newborn mortality and diseases in adulthood. We explored factors related to LBW and PB by conducting a population-based case-control study from January 2011 to December 2013 in Wuhan, China. A total of 337 LBW newborn babies, 472 PB babies, and 708 babies with normal birth weights and born from term pregnancies were included in this study. Information of newborns and their parents was collected by trained investigators using questionnaires and referring to medical records...
April 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28371672/determinants-of-pulmonary-dead-space-in-ventilated-newborn-infants
#19
Theodore Dassios, Ourania Kaltsogianni, Anne Greenough
BACKGROUND: Pulmonary dead space (VD) is an index of ventilation inhomogeneity and one of the determinants of the magnitude of tidal volume to maintain optimal blood gases. AIMS: To identify the determinants of VD in ventilated newborns and to investigate differences in VD between prematurely born and term infants and those prematurely born infants who did or did not develop bronchopulmonary dysplasia (BPD). METHODS: Sixty-one mechanically ventilated infants (15 term, 46 preterm) were studied at a median age of 8 (IQR 2-31) days; 32 of the preterm infants developed BPD...
March 31, 2017: Early Human Development
https://www.readbyqxmd.com/read/28341527/the-relationship-of-maternal-prepregnancy-body-mass-index-and-pregnancy-weight-gain-to-neurocognitive-function-at-age-10-years-among-children-born-extremely-preterm
#20
Elizabeth T Jensen, Jelske W van der Burg, Thomas M O'Shea, Robert M Joseph, Elizabeth N Allred, Tim Heeren, Alan Leviton, Karl C K Kuban
OBJECTIVE: To assess the association between maternal prepregnancy body mass index and adequacy of pregnancy weight gain in relation to neurocognitive function in school-aged children born extremely preterm. STUDY DESIGN: Study participants were 535 ten-year-old children enrolled previously in the prospective multicenter Extremely Low Gestational Age Newborns cohort study who were products of singleton pregnancies. Soon after delivery, mothers provided information about prepregnancy weight...
March 21, 2017: Journal of Pediatrics
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