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https://www.readbyqxmd.com/read/27903746/intestinal-glycolysis-visualized-by-fdg-pet-ct-correlates-with-glucose-decrement-after-gastrectomy
#1
Cheol Ryong Ku, Narae Lee, Jae Won Hong, In Gyu Kwon, Woo Jin Hyung, Sung Hoon Noh, Eun Jig Lee, Mijin Yun, Arthur Cho
Gastrectomy method is known to influence glucose homeostasis. (18)F-fluorodeoxyglucose (FDG) PET/CT acquired after gastrectomy often reveals newly developed physiologic small bowel uptake. We correlated newly developed small bowel FDG uptake and glucose homeostasis in post-gastrectomy gastric cancer patients. We retrospectively analyzed 239 non-diabetic patients who underwent staging and follow-up FDG PET/CT before and after gastrectomy for gastric cancer. Post-operative small bowel glycolysis was quantified by recording intestinal total lesion glycolysis (TLG)...
November 30, 2016: Diabetes
https://www.readbyqxmd.com/read/27900077/selective-beneficial-cardiometabolic-effects-of-vertical-sleeve-gastrectomy-are-predominantly-mediated-through-glucagon-like-peptide-glp-1-in-zucker-diabetic-fatty-rats
#2
Sunil Kumar, Raymond Lau, Thomas Palaia, Christopher Hall, Jenny Lee, Keneth Hall, Collin E Brathwaite, Louis Ragolia
BACKGROUND: Glucagon-like peptide-1 (GLP-1) level was significantly increased post Vertical Sleeve Gastrectomy (VSG), an effect believed to contribute to its beneficial cardiometabolic effects. OBJECTIVE: To validate the beneficial GLP-1 mediated cardiometabolic effects post VSG using GLP-1 antagonist (exendin 9-39) in Zucker diabetic fatty rats. METHODS: Animals were divided into three (n = 5) groups: (i) sham, (ii) VSG, and (iii) VSG received exendin 9-39 (GLP-1 receptor antagonist)...
December 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/27896647/changes-in-non-diabetic-comorbid-disease-status-following-laparoscopic-vertical-sleeve-gastrectomy-lvsg-versus-laparoscopic-roux-en-y-gastric-bypass-lrygb-procedures-a-systematic-review-of-randomized-controlled-trials
#3
Emma Osland, Rossita Mohamad Yunus, Shahjahan Khan, Breda Memon, Muhammed Ashraf Memon
PURPOSE: Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic vertical sleeve gastrectomy (LVSG) have been proposed as cost-effective strategies to manage obesity-related chronic disease. The aim of this systematic review was to study the peer review literature regarding postoperative nondiabetic comorbid disease resolution or improvement reported from randomized controlled trials (RCTs) comparing LVSG and LRYGB procedures. MATERIAL AND METHODS: RCTs comparing postoperative comorbid disease resolution such as hypertension, dyslipidemia, obstructive sleep apnea, joint and musculoskeletal conditions, gastroesophageal reflux disease, and menstrual irregularities following LVSG and LRYGB were included for analysis...
November 28, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27896408/is-routine-prophylactic-cholecystectomy-necessary-during-gastrectomy-for-gastric-cancer
#4
Jun Kimura, Chikara Kunisaki, Ryo Takagawa, Hirochika Makino, Michio Ueda, Mitsuyoshi Ota, Mari Oba, Takashi Kosaka, Hirotoshi Akiyama, Itaru Endo
BACKGROUND: Performing routine prophylactic cholecystectomy during gastrectomy in gastric cancer patients has been controversial. The frequency of cholelithiasis, cholecystitis, and cholangitis after gastrectomy has not been reported for large patient populations, so we carried out this retrospective study to aid the assessment of the necessity for prophylactic cholecystectomy. METHODS: This retrospective study reviewed 969 patients with gastric cancer who underwent distal gastrectomies with Billroth I reconstructions (DG) or total gastrectomies with Roux-en-Y reconstructions (TG), preserving the gallbladder, between January 2000 and May 2012...
November 28, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27895905/outcomes-of-laparoscopic-sleeve-gastrectomy-at-a-bariatric-unit-in-south-africa
#5
Chrysis Sofianos, Constantinos Sofianos
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) has gained popularity over the years as a standalone procedure. In 2014, it was the most rapidly growing bariatric procedure. The aim of this study was to describe the outcomes of LSG at a single bariatric unit in Johannesburg, South Africa, using the Bariatric Analysis and Reporting Outcome System (BAROS) standardised scoring. METHODS: A retrospective record review and analysis was carried out using data collected from patients who had LSGs...
December 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/27890342/impact-of-laparoscopic-roux-en-y-gastric-bypass-versus-sleeve-gastrectomy-on-postoperative-lipid-values
#6
Andrew D Van Osdol, Brandon T Grover, Andrew J Borgert, Kara J Kallies, Shanu N Kothari
BACKGROUND: Metabolic surgery has been shown to significantly improve many obesity-related co-morbidities, including dyslipidemia. The literature has produced mixed results comparing postoperative lipid values after laparoscopic Roux-en-Y gastric bypass (LRYGB) compared to laparoscopic sleeve gastrectomy (LSG); with some indicating significantly greater reductions in total cholesterol and low-density lipoprotein (LDL) in LRYGB versus LSG, and others reporting no significant differences...
October 1, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/27887931/revision-of-primary-sleeve-gastrectomy-to-roux-en-y-gastric-bypass-indications-and-outcomes-from-a-high-volume-center
#7
Robert A Casillas, Scott S Um, Jorge L Zelada Getty, Samantha Sachs, Benjamin B Kim
BACKGROUND: Laparoscopic sleeve gastrectomy (SG) has become an accepted primary bariatric operation. Like other bariatric operations, inadequate weight loss and complications have been reported. OBJECTIVES: The aim of this study was to assess the indications and outcomes of revision of SG to laparoscopic Roux-en-Y gastric bypass (RYGB) at a single community hospital. SETTING: Community hospital, United States. METHODS: Retrospective review of a prospectively collected database identifying SG operations done from February 2009 to June 2014...
October 4, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/27885538/multi-institutional-prospective-feasibility-study-to-explore-tolerability-and-efficacy-of-oral-nutritional-supplements-for-patients-with-gastric-cancer-undergoing-gastrectomy-ccog1301
#8
Daisuke Kobayashi, Kiyoshi Ishigure, Yoshinari Mochizuki, Hiroshi Nakayama, Mitsuru Sakai, Seiji Ito, Hiroshi Kojima, Masaki Kajikawa, Masahiko Ando, Yasuhiro Kodera
BACKGROUND: Postoperative malnutrition after gastrectomy is deemed inevitable, which could have prejudicial influence on survival for gastric cancer patients. A prospective feasibility study was conducted to evaluate the efficacy of postoperative oral nutritional supplements. METHODS: Stage I-III gastric cancer patients who underwent distal or total gastrectomy received oral administration of Racol(®) NF (Otsuka Pharmaceutical Factory, Japan), a liquid enteral nutritional formula, as a supplement to regular meals...
November 24, 2016: Gastric Cancer
https://www.readbyqxmd.com/read/27882512/linear-stapled-side-to-side-esophagojejunostomy-with-hand-sewn-closure-of-the-common-enterotomy-after-prophylactic-and-therapeutic-total-gastrectomy
#9
Kevin K Chang, Madhukar S Patel, Sam S Yoon
After total gastrectomy, anastomosis-related complications such as leak or stricture can be highly morbid. Between July 2005 and December 2015, a linear-stapled side-to-side esophagojejunostomy with hand-sewn closure of the common enterotomy (modified Orringer technique) was used for Roux-en-Y reconstruction after prophylactic total gastrectomy in 22 germline CDH1 mutation carriers and after therapeutic total gastrectomy in 18 patients diagnosed with gastric adenocarcinoma. All operations were performed by the same surgeon...
November 23, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27881023/impaired-gallbladder-function-in-patients-after-total-gastrectomy
#10
Tuula Tyrväinen, Isto Nordback, Jyri Toikka, Anneli Piiroinen, Karl-Heinz Herzig, Kari Mäkelä, Juhani Sand
BACKGROUND AND AIMS: The incidence of gallstones and gallbladder sludge is higher in patients after total gastrectomy than in general population. Formation of gallstones after gastrectomy is multifactorial. Here, we investigate the changes in gallbladder and biliary tract functions by cholescintygraphy and monitored changes in cholecystokinin (CCK) release in long-term survivors after total gastrectomy for gastric carcinoma. MATERIAL AND METHODS: Patients had undergone total gastrectomy for gastric carcinoma at least five years ago...
November 24, 2016: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27878753/helicobacter-pylori-does-not-affect-postoperative-outcomes-after-sleeve-gastrectomy
#11
Hiba Shanti, Neyaf Almajali, Tamador Al-Shamaileh, Walid Samarah, Ayman Mismar, Firas Obeidat
BACKGROUND: The effect of Helicobacter pylori (HP) colonization of the stomach of patients undergoing laparoscopic sleeve gastrectomy (LSG) is unclear. OBJECTIVE: The objective of this study is to evaluate the effect of HP colonization on postoperative outcomes of LSG. SETTING: The setting of this study is in University Hospital. METHODS: This study was a retrospective cohort study of prospectively maintained database of all patients who underwent LSG at Jordan University Hospital from 2008 to 2015...
November 23, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27878423/gastrointestinal-quality-of-life-improves-significantly-after-sleeve-gastrectomy-and-roux-en-y-gastric-bypass-a-prospective-cross-sectional-study-within-a-2-year-follow-up
#12
Felix Nickel, Lukas Schmidt, Thomas Bruckner, Adrian T Billeter, Hannes G Kenngott, Beat-Peter Müller-Stich, Lars Fischer
INTRODUCTION: Morbidly obese patients have lower quality of life (QOL) when compared to the general population. So far, no studies have compared gender and procedural differences in gastrointestinal QOL after sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB). METHODS: Patients before and after bariatric surgery completed the gastrointestinal quality of life index (GIQLI), a 36-item questionnaire with five subscores. Differences between SG and RYGB were analyzed, as were gender differences...
November 22, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27874149/gastroesophageal-stenting-for-the-management-of-post-sleeve-gastrectomy-leak-a-single-institution-experience
#13
Noha Guzaiz, Mohammad Arabi, Azzam Khankan, Refaat Salman, Mohammed Al-Toki, Shahbaz Qazi, Abdulmohsin Alzakari, Mohammad Al-Moaiqel
OBJECTIVES: To retrospectively evaluate the effectiveness of gastroesophageal stenting for post sleeve gastrectomy staple line leaks using removable self-expandable stents. METHODS: Between April 2012 and June 2015, 12 consecutive patients (6 males) with mean age of 34 years (21-38 years) presented with staple line leak 1-8 weeks after the operation (mean 2.8 weeks). Patients underwent gastroesophageal stenting by interventional radiology. A total of 23 stents were deployed with mean length of 17...
December 2016: Saudi Medical Journal
https://www.readbyqxmd.com/read/27871812/effects-of-roux-en-y-gastric-bypass-and-sleeve-gastrectomy-on-bone-mineral-density-and-marrow-adipose-tissue
#14
Miriam A Bredella, Logan B Greenblatt, Alireza Eajazi, Martin Torriani, Elaine W Yu
Bariatric surgery is associated with bone loss but skeletal consequences may differ between Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG), the two most commonly performed bariatric procedures. Furthermore, severe weight loss is associated with high marrow adipose tissue (MAT); however, MAT is also increased in visceral adiposity. The purpose of our study was to determine the effects of RYGB and SG on BMD and MAT. We hypothesized that both bariatric procedures would lead to a decrease in BMD and MAT...
November 15, 2016: Bone
https://www.readbyqxmd.com/read/27869493/laparoscopy-assisted-gastrectomy-in-the-elderly-experience-from-a-uk-centre
#15
A Tandon, I Rajendran, M Aziz, R Kolamunnage-Dona, Q M Nunes, M Shrotri
BACKGROUND Gastric cancer has a high incidence in the elderly in the UK, with a significant number of patients aged 75 years or more. While surgery forms the mainstay of treatment, evidence pertaining to the management of gastric cancer in the Western population in this age group is scarce. METHODS We retrospectively reviewed the outcomes of laparoscopy-assisted total and distal gastrectomies at our centre from 2005 to 2015. Patients aged 70 years or above were included in the elderly group. RESULTS A total of 60 patients underwent laparoscopy-assisted gastrectomy over a 10-year period, with a predominance of male patients...
November 21, 2016: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/27869490/congenital-diaphragmatic-hernia-causing-cardiac-arrest-in-a-30-year-old-woman
#16
H J Manson, Y M Goh, P Goldsmith, P Scott, P Turner
Congenital diaphragmatic hernia (CDH) usually presents in infancy with respiratory failure requiring urgent surgical correction. Mortality in this group of patients remains poor and persistent pulmonary hypertension is a significant contributor. It is therefore rare for patients to reach adulthood undiagnosed. CDH is often identified incidentally in adults but when symptoms arise, they relate to the organ involved, and include gastrointestinal symptoms of dyspepsia and obstruction, as well as respiratory complaints such as dyspnoea...
November 21, 2016: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/27863481/association-of-nutritional-status-related-indices-and-chemotherapy-induced-adverse-events-in-gastric-cancer-patients
#17
Seung Hee Seo, Sung-Eun Kim, Yoon-Koo Kang, Baek-Yeol Ryoo, Min-Hee Ryu, Jae Ho Jeong, Shin Sook Kang, Mihi Yang, Jung Eun Lee, Mi-Kyung Sung
BACKGROUND: Malnutrition in gastrectomized patients receiving chemotherapy is associated with the susceptibility to chemotherapy-related adverse events. This study evaluated pre-operative nutritional status-related indices associated with adverse events in post-operation gastric cancer patients receiving chemotherapy. METHODS: Medical records of 234 gastrectomized patients under adjuvant tegafur/gimeracil/oteracil chemotherapy with extended lymph node dissection were analyzed...
November 18, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27862273/effects-of-argon-plasma-coagulation-on-human-stomach-tissue-an-ex-vivo-study
#18
Eun Jeong Gong, Ji Yong Ahn, Hwoon-Yong Jung, Young Soo Park, Hee Kyong Na, Kee Wook Jung, Do Hoon Kim, Jeong Hoon Lee, Kee Don Choi, Ho June Song, Gin Hyug Lee, Jin-Ho Kim
BACKGROUND AND AIM: Argon plasma coagulation (APC) is a safe alternative treatment for gastrointestinal neoplasms and precancerous lesions. However, the extent of thermal damage after APC is difficult to predict. We investigated the effects of APC on human stomach tissue. METHODS: APC was performed on 10 freshly resected human stomachs which were obtained after total gastrectomy. The effects on tissue were compared across power settings (40, 60, and 80 W), durations (5, 10, 15, 20, and 25 s), and between injection (submucosal injection of normal saline) and control (without injection) groups...
November 14, 2016: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27854246/the-impact-of-impulsivity-on-weight-loss-four-years-after-bariatric-surgery
#19
Kathrin Schag, Isabelle Mack, Katrin E Giel, Sabrina Ölschläger, Eva-Maria Skoda, Maximilian von Feilitzsch, Stephan Zipfel, Martin Teufel
Bariatric surgery has serious implications on metabolic health. The reasons for a failure of bariatric surgery, i.e., limited weight loss, are multifactorial and include psychological factors. We established a theoretical model of how impulsivity is related to weight loss outcome. We propose that depressive symptoms act as a mediator between impulsivity and pathological eating behavior, and that pathological eating behavior has a direct impact on weight loss outcome. We calculated excessive weight loss (%EWL) and assessed self-reported impulsivity (using the Baratt Impulsiveness Scale (BIS-15) total score), depressive symptoms (the Patient Health Questionnaire (PHQ-9) score), and pathological eating behavior (the Eating Disorder Inventory 2 (EDI-2) total score) in 65 patients four years after laparoscopic sleeve gastrectomy...
November 14, 2016: Nutrients
https://www.readbyqxmd.com/read/27853375/total-versus-subtotal-gastrectomy-for-distal-gastric-cancer-meta-analysis-of-randomized-clinical-trials
#20
Lingling Kong, Nianzhao Yang, Lianghui Shi, Guohai Zhao, Minghai Wang, Yisheng Zhang
OBJECTIVES: This meta-analysis of randomized controlled trials was conducted to give a more precise estimation of the efficacy and drawbacks of total gastrectomy (TG) versus subtotal gastrectomy (SG) for proven distal gastric cancer. METHODS: The electronic databases Cochrane and PubMed (updated on April 10, 2016) were searched for randomized controlled trials comparing TG with SG as surgical procedures for distal gastric cancer. Five outcome variables were analyzed, including postoperative complications, anastomotic fistula rate, hospital mortality rate, mortality rate of recurrence (the patient's death is caused by the recurrence of gastric cancer, rather than caused by other diseases), and 5-year survival rate...
2016: OncoTargets and Therapy
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