Read by QxMD icon Read


Glaucia Diniz Alessio, Fernanda Fortes de Araújo, Denise Fonseca Côrtes, Policarpo Ademar Sales Júnior, Daniela Cristina Lima, Matheus de Souza Gomes, Laurence Rodrigues do Amaral, Marcelo Antônio Pascoal Xavier, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Marta de Lana
Distinct Trypanosoma cruzi genotypes have been considered relevant for patient management and therapeutic response of Chagas disease. However, typing strategies for genotype-specific serodiagnosis of Chagas disease are still unavailable and requires standardization for practical application. In this study, an innovative TcI/TcVI/TcII Chagas Flow ATE-IgG2a technique was developed with applicability for universal and genotype-specific diagnosis of T. cruzi infection. For this purpose, the reactivity of serum samples (percentage of positive fluorescent parasites-PPFP) obtained from mice chronically infected with TcI/Colombiana, TcVI/CL or TcII/Y strain as well as non-infected controls were determined using amastigote-AMA, trypomastigote-TRYPO and epimastigote-EPI in parallel batches of TcI, TcVI and TcII target antigens...
March 2017: PLoS Neglected Tropical Diseases
G Sanclemente, C Burgos, J Nova, F Hernández, C González, M I Reyes, N Córdoba, Á Arévalo, E Meléndez, J Colmenares, S Ariza, G Hernández
INTRODUCTION: To date, no formal study has been published regarding how Colombian patients with skin disorders could be affected according to their perception of disease. OBJECTIVE: To determine the impact in quality of life of skin diseases in a Colombian population. METHODS: This multicenter study included patients with skin disease from almost the whole country. Individuals >18 years old; of any gender; with any skin disease and who signed informed consent, were included...
January 4, 2017: Actas Dermo-sifiliográficas
Jorge Sánchez, Ricardo Cardona, Luis Caraballo, Carlos Serrano, Ruth Ramírez, Susana Díez, Elizabeth García, Ana María Segura, Alfonso Cepeda, María Minotas
Allergies comprise a set of highly prevalent diseases. When allergic processes are not controlled, they can endanger patients' health and lives, and have an important economic and social impact. The aim of this paper is to present a practical consensus of the scientific evidence on the use of immunotherapy in allergic diseases. A collaborative review made by various institutes and universities in Colombia was carried out upon request of the Asociación Colombiana de Alergia, Asma e Imunología, led by general practitioners, allergists, immunologists, internists and paediatricians with experience in the field of allergies...
September 1, 2016: Biomédica: Revista del Instituto Nacional de Salud
Alvaro Monterrosa-Castro, Katherin Portela-Buelvas, Heidi C Oviedo, Edwin Herazo, Adalberto Campo-Arias
Introduction. Quality of life could be quantified with the Menopause Rating Scale (MRS), which evaluates the severity of somatic, psychological, and urogenital symptoms in menopause. However, differential item functioning (DIF) analysis has not been applied previously. Objective. To establish the DIF of the psychological domain of the MRS in Colombian women. Methods. 4,009 women aged between 40 and 59 years, who participated in the CAVIMEC (Calidad de Vida en la Menopausia y Etnias Colombianas) project, were included...
2016: BioMed Research International
Olga Marcela Cruz Montalvo
This article analyses the part played by Revista Colombiana de Psiquiatría in the development of psychiatry as a medical speciality in Colombia. Moreover, it discusses its role in helping to consolidate the biomedical perspective and evidence-based medicine in Colombian psychiatry.
October 2016: Revista Colombiana de Psiquiatría
Priscila Moraes Henrique, Tatiane Marques, Marcos Vinícius da Silva, Gabriel Antônio Nogueira Nascentes, Carlo Freire de Oliveira, Virmondes Rodrigues, César Gómez-Hernández, Karen Ann Norris, Luis Eduardo Ramirez, Wendell Sérgio Ferreira Meira
Trypanosoma cruzi trypomastigotes are able to resist lysis via the complement system, which involves many surface proteins including the complement regulatory protein (CRP). To examine the diversity in CRP recognition among strains of T. cruzi, the expression levels of the translated protein on trypomastigote surfaces were analyzed by flow cytometry, and associations between protein expression and the biological behavior of these strains, especially the ability to induce lytic antibodies in animal models, were assessed...
November 2016: Experimental Parasitology
Edenilson Meyer, Diana Marcela Morales Londoño, Rafael Dutra de Armas, Admir José Giachini, Márcio José Rossi, Shantau Camargo Gomes Stoffel, Cláudio Roberto Fonsêca Sousa Soares
Vetiver (Chrysopogon zizanioides) is a fast-growing, high biomass producing plant employed for environmental rehabilitation. The study evaluated the effects of arbuscular mycorrhizal fungi (AMF) on the growth and trace element phytoextracting capabilities of vetiver in a substrate containing coalmine wastes in Southern Brazil. AMF included Acaulospora colombiana, Acaulospora morrowiae, Acaulospora scrobiculata, Dentiscutata heterogama, Gigaspora margarita, and Rhizophagus clarus. Among those, A. colombiana, G...
February 2017: International Journal of Phytoremediation
Thamara Zacca, Ricardo R Siewert, Mirna M Casagrande, Olaf H H Mielke, Márlon Paluch
Four new species of Pierella Westwood, 1851 from Brazil are described: P. angeloi Zacca, Siewert & Mielke sp. nov. from Maranhão, P. kesselringi Zacca, Siewert & Paluch sp. nov. from Paraíba, Pernambuco, Alagoas and Sergipe, P. nice Zacca, Siewert & Paluch sp. nov. from Bahia and P. keithbrowni Siewert, Zacca & Casagrande sp. nov. from Bahia, Espírito Santo, Rio de Janeiro, São Paulo, Paraná and Santa Catarina. Additionally, P. chalybaea Godman, 1905 stat. rest. and P. boliviana F.M. Brown, 1948 stat. nov...
February 9, 2016: Zootaxa
Diego Aguilar Fachin, Cristiane Viera De Assis-Pujol
This family is poor known in Colombia with only two known species of two genera, Solva tuberculata and Arthropeina colombiana.
June 14, 2016: Zootaxa
María Paola Zago, Yashoda M Hosakote, Sue-Jie Koo, Monisha Dhiman, María Dolores Piñeyro, Adriana Parodi-Talice, Miguel A Basombrio, Carlos Robello, Nisha J Garg
Trypanosoma cruzi species is categorized into six discrete typing units (TcI to TcVI) of which TcI is most abundantly noted in the sylvatic transmission cycle and considered the major cause of human disease. In our study, the TcI strains Colombiana (COL), SylvioX10/4 (SYL), and a cultured clone (TCC) exhibited different biological behavior in a murine model, ranging from high parasitemia and symptomatic cardiomyopathy (SYL), mild parasitemia and high tissue tropism (COL), to no pathogenicity (TCC). Proteomic profiling of the insect (epimastigote) and infective (trypomastigote) forms by two-dimensional gel electrophoresis/matrix-assisted laser desorption ionization-time of flight mass spectrometry, followed by functional annotation of the differential proteome data sets (≥2-fold change, P < 0...
June 2016: Infection and Immunity
Ryan A St Laurent, Carlos G C Mielke
Three new genera of Mimallonidae are described. The monotypic genus Tostallo gen. n. is erected to contain "Perophora" albescens Jones, 1912, which was previously placed in the preoccupied genus Perophora Harris, 1841 and was never formally moved to a valid genus. Perophora is a junior homonym of Cicinnus Blanchard, 1852, but the name albescens is not appropriately placed in Cicinnus due to external and genitalia characteristics entirely unique to the species albescens. The female of Tostallo albescens comb...
2016: ZooKeys
Ester Roffê, Ana Paula M P Marino, Joseph Weaver, Wuzhou Wan, Fernanda F de Araújo, Victoria Hoffman, Helton C Santiago, Philip M Murphy
Infectious agents are often considered potential triggers of chronic inflammatory disease, including autoimmunity; however, direct evidence is usually lacking. Here we show that following control of acute infection of mice with the myotropic Colombiana strain of Trypanosoma cruzi, parasites persisted in tissue at low levels associated with development of systemic necrotizing vasculitis. Lesions occurred in many but not all organs and tissues, with skeletal muscle arteries being the most severely affected, and were associated with myositis, atrophy, paresis/paralysis, and death...
April 2016: Infection and Immunity
F H Guedes-da-Silva, D G J Batista, M B Meuser, K C Demarque, T O Fulco, J S Araújo, P B Da Silva, C F Da Silva, D A Patrick, S M Bakunova, S A Bakunov, R R Tidwell, G M Oliveira, C Britto, O C Moreira, M N C Soeiro
Arylimidamides (AIAs) have been shown to have considerable biological activity against intracellular pathogens, includingTrypanosoma cruzi, which causes Chagas disease. In the present study, the activities of 12 novel bis-AIAs and 2 mono-AIAs against different strains ofT. cruziin vitroandin vivowere analyzed. The most active wasm-terphenyl bis-AIA (35DAP073), which had a 50% effective concentration (EC50) of 0.5 μM for trypomastigotes (Y strain), which made it 26-fold more effective than benznidazole (Bz; 13 μM)...
April 2016: Antimicrobial Agents and Chemotherapy
Vítor Gabriel Ambrosini, Joana Gerent Voges, Ludiana Canton, Rafael da Rosa Couto, Paulo Ademar Avelar Ferreira, Jucinei José Comin, George Wellington Bastos de Melo, Gustavo Brunetto, Cláudio Roberto Fonsêca Sousa Soares
High copper (Cu) levels in uprooted old vineyard soils may cause toxicity in transplanted young vines, although such toxicity may be reduced by inoculating plants with arbuscular mycorrhizal fungi (AMF). The objective of this study was to evaluate the effects of AMF on the plant growth, chlorophyll contents, mycorrhizal colonization, and Cu and phosphorus (P) absorption in young vines cultivated in a vineyard soil contaminated by Cu. Commercial vineyard soil with high Cu levels was placed in plastic tubes and transplanted with young vines, which were inoculated with six AMF species (Dentiscutata heterogama, Gigaspora gigantea, Acaulospora morrowiae, A...
October 2015: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
Mayalin Flores, Luis Rojas, Rosa Aparicio, María Eugenia Lucena, Alfredo Usubillaga
Hyptis colombiana is an aromatic shrub native to the Colombian and Venezuelan Andes. Aerial parts were collected in Mérida State at about 3100 m above sea level in February 2005, and May and October 2006. The essential oil was found to contain germacrene D and β-caryophyllene as main constituents (about 50%). The February 2005 and October 2006 oils were found to have antibacterial activity against Staphylococcus aureus, but not the May 2006 oil, probably due to the lack of some minor constituent.
October 2015: Natural Product Communications
Paula M Nogueira, Kleber Ribeiro, Amanda C O Silveira, João H Campos, Olindo A Martins-Filho, Samantha R Bela, Marco A Campos, Natalia L Pessoa, Walter Colli, Maria J M Alves, Rodrigo P Soares, Ana Claudia Torrecilhas
Trypomastigote forms of Trypanosoma cruzi, the causative agent of Chagas Disease, shed extracellular vesicles (EVs) enriched with glycoproteins of the gp85/trans-sialidase (TS) superfamily and other α-galactosyl (α-Gal)-containing glycoconjugates, such as mucins. Here, purified vesicles from T. cruzi strains (Y, Colombiana, CL-14 and YuYu) were quantified according to size, intensity and concentration. Qualitative analysis revealed differences in their protein and α-galactosyl contents. Later, those polymorphisms were evaluated in the modulation of immune responses (innate and in the chronic phase) in C57BL/6 mice...
2015: Journal of Extracellular Vesicles
Carlos Gómez Restrepo
No abstract text is available yet for this article.
June 2012: Revista Colombiana de Psiquiatría
M Romero, Y Moreno, L M Huerfano, M Monroy, M A Camacho
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
M Romero, M Benavides, P Alzate, E Barrios
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
M Romero, P Alzate, R Marrugo, D Vivas, C Urrutia, Y Moreno, S Celis
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"