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https://www.readbyqxmd.com/read/28527344/harnessing-plant-metabolic-diversity
#1
REVIEW
Charlie Owen, Nicola J Patron, Ancheng Huang, Anne Osbourn
Advances in DNA sequencing and synthesis technologies in the twenty-first century are now making it possible to build large-scale pipelines for engineering plant natural product pathways into heterologous production species using synthetic biology approaches. The ability to decode the chemical potential of plants by sequencing their transcriptomes and/or genomes and to then use this information as an instruction manual to make drugs and other high-value chemicals is opening up new routes to harness the vast chemical diversity of the Plant Kingdom...
May 17, 2017: Current Opinion in Chemical Biology
https://www.readbyqxmd.com/read/28524714/consumption-patterns-of-nightlife-attendees-in-munich-a-latent-class-analysis
#2
Tessa-Virginia Hannemann, Ludwig Kraus, Daniela Piontek
BACKGROUND: The affinity for substance use among patrons of nightclubs has been well established. With novel psychoactive substances (NPS) quickly emerging on the European drug market, trends, and patterns of use are potentially changing. OBJECTIVES: (1) The detection of subgroups of consumers in the electronic dance music scene of a major German metropolitan city, (2) describing the consumption patterns of these subgroups, (3) exploring the prevalence and type of NPS consumption in this population at nightlife events in Munich...
May 19, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28513373/philip-a-prince-among-men
#3
Stanley Holder
Following the announcement that Prince Philip will withdraw from public duties, I should like to place on record the gratitude of male nurses when, as patron of the Society of Registered Male Nurses, he encouraged the career development of men in the profession.
May 17, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28510267/the-jack-wills-crowd-towards-a-sociology-of-an-elite-subculture
#4
Anthony King, Daniel Smith
British sociologists have long been interested in youth sub-cultures. However British sociologists have tended to focus on working class subcultures and avoided engagement with exclusive sub-cultures of elite social groups. This article seeks to attend to this gap by examining the subculture of a British elite: ex-public school students at select universities in the UK in the twenty-first century. This group consists of a relatively small group of young adults, aged between 18 and 23, who attended public schools, especially one of the nine Clarendon schools (Eton, Winchester, Westminster, St...
May 16, 2017: British Journal of Sociology
https://www.readbyqxmd.com/read/28508680/personality-and-destiny-francesco-borromini-portrait-of-a-tormented-soul
#5
Gabriele Cipriani, Luca Cipriani, Mario Di Fiorino
Francesco Borromini, one of the great geniuses of Baroque architecture, was tormented and solitary, and was increasingly frustrated by the fame and success of his rival, Gian Lorenzo Bernini. Borromini was an unhappy man, constantly dogged by disaster, quarrelling even with his best patrons and closest friends. In the culmination of one of the fits of depression that overcame the architect more and more frequently as his life progressed, Borromini literally fell on his own sword; he lingered in excruciating pain for 24 hours before dying...
May 1, 2017: History of Psychiatry
https://www.readbyqxmd.com/read/28506419/radioguided-thyroidectomy-for-follicular-tumors-multicentric-experience
#6
D Parmeggiani, C Gambardella, R Patrone, A Polistena, M De Falco, R Ruggiero, R Cirocchi, A Sanguinetti, V Cuccurullo, M Accardo, N Avenia, G Docimo, S Tolone, V Bassi, L Docimo, G Conzo
BACKGROUND: The diagnosis of thyroid nodular diseases requires an integrated approach that has been widely established over the past years. This strategy includes: ultrasonography (US) with; implemented Color-Power-Doppler, conventional scintigraphy also with positive indicators, specific pathological studies targeted by immunohistochemically-assays, and the fine needle; aspiration biopsy (FNAB), which, usually, in case of "Follicular Lesions" (10-20%) findings is; unable to distinguish carcinoma from follicular adenoma, then indicating the necessity of surgery to; obtain a correct diagnosis...
May 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28506414/unintentional-recurrent-laryngeal-nerve-injuries-following-thyroidectomy-is-it-the-surgeon-who-pays-the-bill
#7
REVIEW
C Gambardella, A Polistena, A Sanguinetti, R Patrone, S Napolitano, D Esposito, D Testa, V Marotta, A Faggiano, P G Calò, N Avenia, G Conzo
BACKGROUND: Thyroidectomy is one of the most common intervention in general surgery and, after the turn of the century, its rate has sharply increased, along with a worldwide increased incidence of differentiated thyroid cancers. Therefore, injuries of the recurrent laryngeal nerve have become one of the most frequent cause of surgical malpractice claims, mostly following surgery for benign pathology. MAIN BODY: Even if the incidence of definitive paralysis is generally lower than 3%, during the last 20 years in Italy, the number of claims for damages has sharply raised...
May 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28501550/type-2-diabetes-alters-hippocampal-gamma-oscillations-a-potential-mechanism-behind-impaired-cognition
#8
Grazyna Lietzau, Vladimer Darsalia, Hiranya Pintana, Claes-Göran Östenson, Thomas Nyström, André Fisahn, Cesare Patrone
Type 2 diabetes (T2D) has been associated with cognitive decline, dementia and Alzheimer's disease (AD). Remarkably, the pathophysiological mechanisms behind this are still mostly unknown. Cognition and memory formation are associated with gamma oscillations in hippocampal neuronal networks and fast-spiking, parvalbumin-expressing interneurons (PV+ IN) play a key role in these processes.
April 27, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28495220/other-tobacco-product-use-among-sexual-minority-young-adult-bar-patrons
#9
Amanda Fallin-Bennett, Nadra E Lisha, Pamela M Ling
INTRODUCTION: Lesbian, gay, and bisexual (LGB) individuals smoke at rates 1.5-2 times higher than the general population, but less is known about LGB consumption of other tobacco products (OTPs) and gender differences. OTP use among young adult LGB bar patrons and the relationship among past quit attempts, intention to quit, and binge drinking with OTP use was examined. METHODS: A cross-sectional survey of young adults (aged 18-26) in bars/nightclubs in seven U...
May 8, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28492632/photo-assisted-inactivation-of-escherichia-coli-bacteria-by-silver-functionalized-titanate-nanotubes-ag-h2ti2o5%C3%A2-h2o
#10
A Patrón-Soberano, B P Núñez-Luna, S Casas-Flores, A De Las Peñas, R B Domínguez-Espíndola, V Rodríguez-González
One-dimensional titanate nanotubes (H2Ti2O5·H2O) functionalized with silver nanoparticles (AgNPs) exhibited unique properties for the effective inactivation of the Gram-negative Escherichia coli within 45 minutes under irradiation using a 65 W halogen lamp. The pathway of the photo-assisted catalytic inactivation was examined by SEM and TEM using a reproducible biological protocol for sample preparations. The membrane integrity of the bacteria was damaged due to the oxidative stress caused by the reactive oxygen species, the bacteriostatic effect of the highly-dispersed-surface AgNPs (∼5 nm) and the sharp nanotube penetration that induced the cell death...
May 11, 2017: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/28484961/environmental-factors-associated-with-psychotropic-drug-use-in-brazilian-nightclubs
#11
Claudia Carlini, Solange Andreoni, Zila M Sanchez
The purpose of this study was to identify environmental factors associated with patterns of psychotropic drug use in nightclubs. Mixed methods were used to investigate psychotropic drugs consumption among patrons of 31 nightclubs in São Paulo, Brazil. A total of 1822 patrons at the entrance and exit of the venues and 30 staff members of the nightclubs were interviewed. The observational data were collected through 307 h of observational research using a structured guide to register environmental measures...
May 8, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28476114/restaurant-based-intervention-to-facilitate-healthy-eating-choices-and-the-identification-of-allergenic-foods-at-a-family-oriented-resort-and-a-campground
#12
Lucia Tarro, Magaly Aceves-Martins, Yolanda Tiñena, Joan Lluís Parisi, Xavier Blasi, Montse Giralt, Elisabet Llauradó, Rosa Solà
BACKGROUND: Restaurant-based interventions can be an enjoyable way to encourage healthier eating choices by all members of a family. Thus, the principal aims of this study were a) to promote healthy diets by increasing healthy food offerings and b) to increase the number of foods offered specifically as gluten-free and lactose-free and to inform patrons by including nutritional and allergen information that complies with Regulation 1169/2011 regarding the food served in restaurants, takeaways and snack bars...
May 5, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28473746/practices-related-to-tobacco-sale-promotion-and-protection-from-tobacco-smoke-exposure-in-restaurants-and-bars-in-kampala-before-implementation-of-the-uganda-tobacco-control-act-2015
#13
Steven Ndugwa Kabwama, Daniel Kadobera, Sheila Ndyanabangi, Kellen Namusisi Nyamurungi, Shannon Gravely, Lindsay Robertson, David Guwatudde
BACKGROUND: The Word Health Organization's Framework Convention on Tobacco Control calls on parties to implement evidenced-based tobacco control policies, which includes Article 8 (protect the public from exposure to tobacco smoke), and Article 13 (tobacco advertising, promotion and sponsorship (TAPS)). In 2015, Uganda passed the Tobacco Control Act 2015 which includes a comprehensive ban on smoking in all public places and on all forms of TAPS. Prior to implementation, we sought to assess practices related to protection of the public from tobacco smoke exposure, limiting access to tobacco products and TAPS in restaurants and bars in Kampala City to inform implementation of the new law...
2017: Tobacco Induced Diseases
https://www.readbyqxmd.com/read/28472461/patient-reported-impact-of-after-hours-house-call-services-on-the-utilization-of-emergency-department-services-in-australia
#14
Chris O Ifediora, Gary D Rogers
Objectives.: This paper explores, from the patients' perspective, the likely impact of the Australian after-hours house-call (AHHC) medical services on emergency department (ED) presentations. This has become imperative given the significant cost difference between patient presentations to either the AHHC or ED and their practical implications for health care funding. Design, setting and participants.: A cross-sectional, self-reported survey of all 10 838 patients in Australia known to have patronized AHHC services over the last week of January 2016...
May 2, 2017: Family Practice
https://www.readbyqxmd.com/read/28458091/residential-segregation-political-representation-and-preterm-birth-among-u-s-and-foreign-born-black-women-in-the-u-s-2008-2010
#15
Claire Margerison-Zilko, Maria Perez-Patron, Catherine Cubbin
Although racial residential segregation is associated with preterm birth (PTB) among non-Hispanic black (NHB) women in the U.S., prior work suggests that increased black political power arising from segregation may be protective for infant health. We examined associations between residential segregation, black political representation, and preterm birth (PTB) among U.S- and foreign-born NHB women in major U.S. cities using birth certificate data from 2008 to 2010 (n=861,450). Each 10-unit increase in segregation was associated with 3-6% increases in odds of PTB for both U...
April 27, 2017: Health & Place
https://www.readbyqxmd.com/read/28453417/experience-challenges-and-opportunities-of-being-fully-embedded-in-a-user-group
#16
Lin Wu, Joel Thornton
Embedded librarian models can assume different forms and levels, depending on patron needs and a library's choice of delivery services. An academic health sciences library decided to enhance its service delivery model by integrating a librarian into the College of Pharmacy, approximately 250 miles away from the main library. This article describes the embedded librarian's first-year experience, challenges, and opportunities working as a library faculty in the college. The comparison of one-year recorded statistics on preembedded and postembedded activities demonstrated the effectiveness and impact of such an embedded librarian model...
April 2017: Medical Reference Services Quarterly
https://www.readbyqxmd.com/read/28452107/neuroinvasive-st-louis-encephalitis-virus-infection-in-solid-organ-transplant-recipients
#17
Carlos A Hartmann, Holenarasipur R Vikram, Maria T Seville, Robert Orenstein, Shimon Kusne, Janis E Blair, Thomas E Grys, Roberto L Patron
In the summer of 2015, 3 unrelated solid organ transplant recipients had meningoencephalitis suggestive of West Nile virus (WNV) infection in Phoenix, Arizona. Testing was inconclusive but was later confirmed as St. Louis encephalitis (SLE). We retrospectively reviewed clinical manifestations, treatment, and outcomes of these transplant recipients. Common symptoms were fever, rigors, diarrhea, headache, and confusion. One patient died 3 days after hospitalization. Therapy for the 2 patients was initiated with interferon alfa-2b (IFN) and intravenous immunoglobulin G (IVIG) (IFN+IVIG in combination)...
April 27, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28444569/a-new-science-publishing-system-for-a-budding-science-publishing-crisis
#18
Carlos Fernandez-Patron, Eugenio Hardy
The current science publishing system is in need of a positive transformation for the good of scientists and society as a whole. Herein, we propose features that, in our view, will distinguish the science publishing system of the future.
April 25, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28440068/correlates-of-verbal-and-physical-aggression-among-patrons-of-licensed-venues-in-australia
#19
Shannon Hyder, Kerri Coomber, Amy Pennay, Nicolas Droste, Ashlee Curtis, Richelle Mayshak, Tina Lam, William Gilmore, Tanya Chikritzhs, Peter G Miller
INTRODUCTION AND AIMS: The current study aimed to examine the association between patron demographics and substance use, and experiences of verbal and physical aggressive incidents within the last 3 months among patrons of night-time entertainment precincts (NEP) in Australia. DESIGN AND METHODS: Patron interviews (n = 4216) were conducted around licensed venues in the NEPs of five Australian cities. Seven correlates of verbal and physical aggressive incidents were examined: gender, age, occupation, blood alcohol concentration, pre-drinking, energy drink use and illicit drug use in the current session...
April 25, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28436262/private-philanthropy-and-basic-research-in-mid-twentieth-century-america-the-hickrill-chemical-research-foundation
#20
Leon Gortler, Stephen J Weininger
The Hickrill Chemical Research Foundation, located north of New York City on the estate of its patrons, Sylvan and Ruth Alice Norman Weil, had a short (1948-59) but productive life. Ruth Alice Weil received a Ph.D. in organic chemistry in 1947, directed by William von Eggers Doering of Columbia University. She intended that Hickrill contribute to cancer chemotherapy while providing resources for Doering's more speculative research. Ultimately, Doering's commitment to theoretical organic chemistry set Hickrill's research agenda...
April 24, 2017: Ambix
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