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https://www.readbyqxmd.com/read/29659539/post-game-high-protein-intake-may-improve-recovery-of-football-specific-performance-during-a-congested-game-fixture-results-from-the-pro-football-study
#1
Athanasios Poulios, Ioannis G Fatouros, Magni Mohr, Dimitrios K Draganidis, Chariklia Deli, Konstantinos Papanikolaou, Apostolos Sovatzidis, Theofano Nakopoulou, Georgios Ermidis, Theofanis Tzatzakis, Vasiliki C Laschou, Kalliopi Georgakouli, Agisilaos Koulouris, Panagiotis Tsimeas, Athanasios Chatzinikolaou, Leonidas G Karagounis, Dimitrios Batsilas, Peter Krustrup, Athanasios Z Jamurtas
The effects of protein supplementation on performance recovery and inflammatory responses during a simulated one-week in-season microcycle with two games (G1, G2) performed three days apart were examined. Twenty football players participated in two trials, receiving either milk protein concentrate (1.15 and 0.26 g/kg on game and training days, respectively) (PRO) or an energy-matched placebo (1.37 and 0.31 g/kg of carbohydrate on game and training days, respectively) (PLA) according to a randomized, repeated-measures, crossover, double-blind design...
April 16, 2018: Nutrients
https://www.readbyqxmd.com/read/29622449/one-year-clinical-outcome-of-biodegradable-polymer-sirolimus-eluting-stent-in-all-comers-population-insight-from-the-ulisse-registry-ultimaster-italian-multicenter-all-comers-stent-registry
#2
Cosmo Godino, Alessandro Beneduce, Giuseppe Ferrante, Alfonso Ielasi, Andrea Carlo Pivato, Mauro Chiarito, Alberto Cappelletti, Giulia Perfetti, Valeria Magni, Eugenio Prati, Stefania Falcone, Adele Pierri, Stefano De Martini, Matteo Montorfano, Rosario Parisi, David Rutigliano, Nicola Locuratolo, Angelo Anzuini, Maurizio Tespilli, Alberto Margonato, Alberto Benassi, Carlo Briguori, Franco Fabbiocchi, Bernhard Reimers, Antonio Bartorelli, Antonio Colombo
BACKGROUND: This study was designed to confirm in a large population of unselected patients the promising results of Ultimaster® biodegradable polymer sirolimus-eluting stent (BP-SES) already shown in previous trial. METHODS: ULISSE is an observational, multicenter, national registry evaluating all patients undergoing PCI with the Ultimaster® BP-SES. Incidence of 1-year TLF (cardiac death or target vessel MI or clinically indicated TLR) was the primary endpoint...
June 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29619795/switching-between-pitch-surfaces-practical-applications-and-future-perspectives-for-soccer-training
#3
Vincenzo Rago, João R Silva, João Brito, Daniel Barreira, Magni Mohr, Peter Krustrup, António N Rebelo
Soccer training and completion is conventionally practiced on natural grass (NG) or artificial turf (AT). Recently, AT pitches for training / competition, and of unstable surfaces for injury prevention training has increased. Therefore, soccer players are frequently exposed to variations in pitch surface during either training or competition. These ground changes may impact physical and physiological responses, adaptations as well as the injury. The aim of this review was to summarize the acute physical and physiological responses, chronic adaptations, and injury risk associated with exercising on different pitch surfaces in soccer...
April 4, 2018: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29599862/fatigue-responses-in-various-muscle-groups-in-well-trained-competitive-male-players-after-a-simulated-soccer-game
#4
Dan Fransson, Jeppe Foged Vigh-Larsen, Ioannis G Fatouros, Peter Krustrup, Magni Mohr
We examined the degree of post-game fatigue and the recovery pattern in various leg and upper-body muscle groups after a simulated soccer game. Well-trained competitive male soccer players (n = 12) participated in the study. The players completed the Copenhagen Soccer Test, a 2 x 45 min simulated soccer protocol, following baseline measures of maximal voluntary contractions of multiple muscle groups and systemic markers of muscle damage and inflammation at 0, 24 and 48 h into recovery. All muscle groups had a strength decrement ( p ≤ 0...
March 2018: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29581064/molecular-signatures-of-medullary-thyroid-carcinoma-by-matrix-assisted-laser-desorption-ionisation-mass-spectrometry-imaging
#5
Andrew Smith, Manuel Galli, Isabella Piga, Vanna Denti, Martina Stella, Clizia Chinello, Nicola Fusco, Davide Leni, Marco Manzoni, Gaia Roversi, Mattia Garancini, Angela Ida Pincelli, Vincenzo Cimino, Giulia Capitoli, Fulvio Magni, Fabio Pagni
The main aim of the study was to assess the feasibility of matrix-assisted laser desorption/ionisation mass spectrometry imaging (MALDI-MSI) in the pathological investigation of Medullary Thyroid Carcinoma (MTC). Formalin-fixed paraffin-embedded (FFPE) samples from seven MTC patients were analysed by MALDI-MSI in order to detect proteomic alterations within tumour lesions and to define the molecular profiles of specific findings, such as amyloid deposition and C cell hyperplasia (CCH). nLC-ESI MS/MS was employed for the identification of amyloid components and to select alternative proteomic markers of MTC pathogenesis...
March 24, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29575824/complex-bayesian-modeling-workflows-encoding-and-execution-made-easy-with-a-novel-winbugs-plugin-of-the-drug-disease-model-resources-interoperability-framework
#6
Cristiana Larizza, Elisa Borella, Lorenzo Pasotti, Palma Tartaglione, Mike Smith, Stuart Moodie, Paolo Magni
The Drug Disease Model Resources (DDMoRe) Interoperability Framework (IOF) enables pharmacometric model encoding and execution via Model Description Language (MDL) and R language, through the ddmore package. Through its components and converter plugins, the IOF can execute pharmacometric tasks using different target tools, starting from a single MDL-encoded model. In this article, we present the WinBUGS plugin and show how its integration in the IOF enables an easy implementation of complex Bayesian workflows...
March 25, 2018: CPT: Pharmacometrics & Systems Pharmacology
https://www.readbyqxmd.com/read/29573496/molecular-diversity-and-landscape-genomics-of-the-crop-wild-relative-triticum-urartu-across-the-fertile-crescent
#7
Alice Brunazzi, Davide Scaglione, Rebecca Fiorella Talini, Mara Miculan, Federica Magni, Jesse Poland, Mario Enrico Pè, Andrea Brandolini, Matteo Dell'Acqua
Modern plant breeding can benefit from the allelic variation existing in natural populations of crop wild relatives that evolved under natural selection in varying pedoclimatic conditions. In this study, next-generation sequencing was used to generate 1.3 million genome-wide SNPs on ex situ collections of Triticum urartu L., the wild donor of the Au sub-genome of modern wheat. A set of 75,511 high quality SNPs were retained to describe 298 T. urartu accessions collected throughout the Fertile Crescent. Triticum urartu showed a complex pattern of genetic diversity, with two main genetic groups distributed sequentially from West to East...
March 24, 2018: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/29556421/normative-ultrasound-references-for-the-paediatric-wrist-dorsal-soft-tissues
#8
Karen Rosendahl, Ingvild Sævold Bruserud, Ninnie Oehme, Pétur Benedikt Júlíusson, Laura Tanturri de Horatio, Lil-Sofie Ording Müller, Silvia Magni-Manzoni
Objective: To report novel ultrasound (US) references for the healthy paediatric wrist. Methods: Healthy children and adolescents had an US examination including Doppler, of the right wrist, using a mid-sagittal image through the radiocarpal (RC)/midcarpal (MC) joints. These features were noted: appearances and depth of the recess, with an additional measurement in the flexed position and number of Doppler signals within the recess in close proximity to the joint...
2018: RMD Open
https://www.readbyqxmd.com/read/29546238/variations-in-the-amount-of-water-ice-on-ceres-surface-suggest-a-seasonal-water-cycle
#9
Andrea Raponi, Maria Cristina De Sanctis, Alessandro Frigeri, Eleonora Ammannito, Mauro Ciarniello, Michelangelo Formisano, Jean-Philippe Combe, Gianfranco Magni, Federico Tosi, Filippo Giacomo Carrozzo, Sergio Fonte, Marco Giardino, Steven P Joy, Carol A Polanskey, Marc D Rayman, Fabrizio Capaccioni, Maria Teresa Capria, Andrea Longobardo, Ernesto Palomba, Francesca Zambon, Carol A Raymond, Christopher T Russell
The dwarf planet Ceres is known to host a considerable amount of water in its interior, and areas of water ice were detected by the Dawn spacecraft on its surface. Moreover, sporadic water and hydroxyl emissions have been observed from space telescopes. We report the detection of water ice in a mid-latitude crater and its unexpected variation with time. The Dawn spectrometer data show a change of water ice signatures over a period of 6 months, which is well modeled as ~2-km2 increase of water ice. The observed increase, coupled with Ceres' orbital parameters, points to an ongoing process that seems correlated with solar flux...
March 2018: Science Advances
https://www.readbyqxmd.com/read/29546235/nature-formation-and-distribution-of-carbonates-on-ceres
#10
Filippo Giacomo Carrozzo, Maria Cristina De Sanctis, Andrea Raponi, Eleonora Ammannito, Julie Castillo-Rogez, Bethany L Ehlmann, Simone Marchi, Nathaniel Stein, Mauro Ciarniello, Federico Tosi, Fabrizio Capaccioni, Maria Teresa Capria, Sergio Fonte, Michelangelo Formisano, Alessandro Frigeri, Marco Giardino, Andrea Longobardo, Gianfranco Magni, Ernesto Palomba, Francesca Zambon, Carol A Raymond, Christopher T Russell
Different carbonates have been detected on Ceres, and their abundance and spatial distribution have been mapped using a visible and infrared mapping spectrometer (VIR), the Dawn imaging spectrometer. Carbonates are abundant and ubiquitous across the surface, but variations in the strength and position of infrared spectral absorptions indicate variations in the composition and amount of these minerals. Mg-Ca carbonates are detected all over the surface, but localized areas show Na carbonates, such as natrite (Na2 CO3 ) and hydrated Na carbonates (for example, Na2 CO3 ·H2 O)...
March 2018: Science Advances
https://www.readbyqxmd.com/read/29544181/evaluation-of-uptake-and-chronic-toxicity-of-virgin-polystyrene-microbeads-in-freshwater-zebra-mussel-dreissena-polymorpha-mollusca-bivalvia
#11
Stefano Magni, François Gagné, Chantale André, Camilla Della Torre, Joëlle Auclair, Houda Hanana, Camilla Carla Parenti, Francesco Bonasoro, Andrea Binelli
Microplastics (MPs), plastic debris smaller than 5mm, are widely found in both marine and freshwater ecosystems. However, few studies regarding their hazardous effects on inland water organisms, have been conducted. For this reason, the aim of our research was the evaluation of uptake and chronic toxicity of two mixtures (MIXs) of virgin polystyrene microbeads (PMs) of 10μm and 1μm in size (MIX 1, with 5×105 of 1μmsizePMs/L and 5×105 of 10μmsizePMs/L, and MIX 2 with 2×106 of 1μmsizePMs/L and 2×106 of 10μmsizePMs/L) on freshwater zebra mussel Dreissena polymorpha (Mollusca: Bivalvia) during 6 exposure days...
March 12, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29542338/affinity-enrichment-for-mass-spectrometry-improving-the-yield-of-low-abundance-biomarkers
#12
Brianna Kim, Robyn Araujo, Marissa Howard, Ruben Magni, Lance A Liotta, Alessandra Luchini
Mass spectrometry (MS) is the premier tool for discovering novel disease-associated protein biomarkers. Unfortunately, when applied to complex body fluid samples, MS has poor sensitivity for the detection of low abundance biomarkers (≪10 ng/mL), derived directly from the diseased tissue cells or pathogens. Areas covered: Herein we discuss the strengths and drawbacks of technologies used to concentrate low abundance analytes in body fluids, with the aim to improve the effective sensitivity for MS discovery...
March 22, 2018: Expert Review of Proteomics
https://www.readbyqxmd.com/read/29532423/body-composition-and-metabolic-changes-during-a-520-day-mission-simulation-to-mars
#13
F Strollo, C Macchi, I Eberini, M A Masini, M Botta, G Vassilieva, I Nichiporuk, M Monici, D Santucci, F Celotti, P Magni, M Ruscica
PURPOSE: The "Mars-500 project" allowed to evaluate the changes in psychological/physiological adaptation over a prolonged confinement, in order to gather information for future missions. Here, we evaluated the impact of confinement and isolation on body composition, glucose metabolism/insulin resistance and adipokine levels. METHODS: The "Mars-500 project" consisted of 520 consecutive days of confinement from June 3, 2010 to Nov 4, 2011. The crew was composed of six male subjects (three Russians, two Europeans, and one Chinese) with a median age of 31 years (range 27-38 years)...
March 12, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29526269/the-effect-of-antifreeze-ethylene-glycol-on-the-survival-and-the-life-cycle-of-two-species-of-necrophagous-blowflies-diptera-calliphoridae
#14
Abrar Essarras, Marco Pazzi, Ian R Dadour, Paola A Magni
Entomotoxicology involves the analysis of the presence and the effects of toxicological substances in necrophagous insects. Results obtained by entomotoxicological studies may assist in the investigation of both the causes and the time of death of humans and animals. Ethylene glycol (EG) is easy to purchase, sweet and extremely toxic. It may be consumed accidentally or purposefully, in an attempt to cause death for suicidal or homicidal intent. Several cases report fatalities of humans and animals. The present study is the first to examine the effects of EG on the survival, developmental rate and morphology of two blowfly species, (Diptera: Calliphoridae) typically found on corpses and carcasses: Lucilia sericata (Meigen) and L...
March 2018: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/29506713/relationship-between-syntax-score-and-prognostic-localization-of-coronary-artery-lesions-with-conventional-risk-factors-plasma-profile-markers-and-carotid-atherosclerosis-capp-study-2
#15
Alberto Cappelletti, Domenico Astore, Cosmo Godino, Barbara Bellini, Valeria Magni, Monica Mazzavillani, Matteo Pagnesi, Eustachio Agricola, Roberto Chiesa, Antonio Colombo, Alberto Margonato
BACKGROUND: Data concerning the relationship between cardiovascular risk factors, plasmatic markers, carotid disease and extent of coronary lesions are lacking. OBJECTIVES: To evaluate the role of cardiovascular risk factors, plasmatic levels of high sensitivity C-reactive protein (hs-CRP), fibrinogen, lipoprotein(a), and carotid plaque extension in predicting the severity of coronary artery disease (CAD). METHODS: We analyzed 574 subjects undergoing first coronary angiography...
April 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29504906/features-of-the-organization-of-bread-wheat-chromosome-5bs-based-on-physical-mapping
#16
Elena A Salina, Mikhail A Nesterov, Zeev Frenkel, Antonina A Kiseleva, Ekaterina M Timonova, Federica Magni, Jan Vrána, Jan Šafář, Hana Šimková, Jaroslav Doležel, Abraham Korol, Ekaterina M Sergeeva
BACKGROUND: The IWGSC strategy for construction of the reference sequence of the bread wheat genome is based on first obtaining physical maps of the individual chromosomes. Our aim is to develop and use the physical map for analysis of the organization of the short arm of wheat chromosome 5B (5BS) which bears a number of agronomically important genes, including genes conferring resistance to fungal diseases. RESULTS: A physical map of the 5BS arm (290 Mbp) was constructed using restriction fingerprinting and LTC software for contig assembly of 43,776 BAC clones...
February 9, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29484298/improved-exercise-tolerance-with-caffeine-is-associated-with-modulation-of-both-peripheral-and-central-neural-processes-in-human-participants
#17
Joanna L Bowtell, Magni Mohr, Jonathan Fulford, Sarah R Jackman, Georgios Ermidis, Peter Krustrup, Katya N Mileva
Background: Caffeine has been shown to enhance exercise performance and capacity. The mechanisms remain unclear but are suggested to relate to adenosine receptor antagonism, resulting in increased central motor drive, reduced perception of effort, and altered peripheral processes such as enhanced calcium handling and extracellular potassium regulation. Our aims were to investigate how caffeine (i) affects knee extensor PCr kinetics and pH during repeated sets of single-leg knee extensor exercise to task failure and (ii) modulates the interplay between central and peripheral neural processes...
2018: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29474380/predisposing-and-precipitating-factors-for-delirium-in-community-dwelling-older-adults-admitted-to-hospital-with-this-condition-a-prospective-case-series
#18
Emmanuelle Magny, Hélène Le Petitcorps, Maria Pociumban, Zineb Bouksani-Kacher, Éric Pautas, Joël Belmin, Sylvie Bastuji-Garin, Carmelo Lafuente-Lafuente
BACKGROUND: Factors associated with delirium among community-dwelling older adults have been poorly studied. Our aim was to describe the prevalence of predisposing and precipitating factors for delirium among patients admitted for delirium and to assess whether these factors were appropriately recognized at the first patient assessment at hospital. METHODS: Consecutive community-dwelling individuals admitted to three geriatric acute care units with a confirmed initial diagnosis of delirium were prospectively included...
2018: PloS One
https://www.readbyqxmd.com/read/29462917/characterization-and-determination-of-interesterification-markers-triacylglycerol-regioisomers-in-confectionery-oils-by-liquid-chromatography-mass-spectrometry
#19
Valentina Santoro, Federica Dal Bello, Riccardo Aigotti, Daniela Gastaldi, Francesco Romaniello, Emanuele Forte, Martina Magni, Claudio Baiocchi, Claudio Medana
Interesterification is an industrial transformation process aiming to change the physico-chemical properties of vegetable oils by redistributing fatty acid position within the original constituent of the triglycerides. In the confectionery industry, controlling formation degree of positional isomers is important in order to obtain fats with the desired properties. Silver ion HPLC (High Performance Liquid Chromatography) is the analytical technique usually adopted to separate triglycerides (TAGs) having different unsaturation degrees...
February 16, 2018: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/29431879/life-stage-associated-remodeling-of-lipid-metabolism-regulation-in-atlantic-salmon
#20
Gareth Gillard, Thomas N Harvey, Arne Gjuvsland, Yang Jin, Magny Thomassen, Sigbjørn Lien, Michael Leaver, Jacob S Torgersen, Torgeir R Hvidsten, Jon Olav Vik, Simen R Sandve
Atlantic salmon migrates from rivers to sea to feed, grow and develop gonads before returning to spawn in freshwater. The transition to marine habitats is associated with dramatic changes in the environment, including water salinity, exposure to pathogens, and shift in dietary lipid availability. Many changes in physiology and metabolism occur across this life-stage transition, but little is known about the molecular nature of these changes. Here we use a long term feeding experiment to study transcriptional regulation of lipid metabolism in Atlantic salmon gut and liver in both fresh- and saltwater...
February 12, 2018: Molecular Ecology
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