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https://www.readbyqxmd.com/read/29237757/urine-lipoarabinomannan-glycan-in-hiv-negative-patients-with-pulmonary-tuberculosis-correlates-with-disease-severity
#1
Luisa Paris, Ruben Magni, Fatima Zaidi, Robyn Araujo, Neal Saini, Michael Harpole, Jorge Coronel, Daniela E Kirwan, Hannah Steinberg, Robert H Gilman, Emanuel F Petricoin, Roberto Nisini, Alessandra Luchini, Lance Liotta
An accurate urine test for pulmonary tuberculosis (TB), affecting 9.6 million patients worldwide, is critically needed for surveillance and treatment management. Past attempts failed to reliably detect the mycobacterial glycan antigen lipoarabinomannan (LAM), a marker of active TB, in HIV-negative, pulmonary TB-infected patients' urine (85% of 9.6 million patients). We apply a copper complex dye within a hydrogel nanocage that captures LAM with very high affinity, displacing interfering urine proteins. The technology was applied to study pretreatment urine from 48 Peruvian patients, all negative for HIV, with microbiologically confirmed active pulmonary TB...
December 13, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/29211336/diverse-effects-of-invasive-ecosystem-engineers-on-marine-biodiversity-and-ecosystem-functions-a-global-review-and-meta-analysis
#2
Tamar Guy-Haim, Devin A Lyons, Jonne Kotta, Henn Ojaveer, Ana M Queirós, Eva Chatzinikolaou, Christos Arvanitidis, Serena Como, Paolo Magni, Andrew J Blight, Helen Orav-Kotta, Paul J Somerfield, Tasman P Crowe, Gil Rilov
Invasive ecosystem engineers (IEE) are potentially one of the most influential types of biological invaders. They are expected to have extensive ecological impacts by altering the physical-chemical structure of ecosystems, thereby changing the rules of existence for a broad range of resident biota. To test the generality of this expectation, we used a global systematic review and meta-analysis to examine IEE effects on the abundance of individual species and communities, biodiversity (using several indices) and ecosystem functions, focusing on marine and estuarine environments...
December 6, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29208417/multiple-digit-melanonychia-examine-the-scalp
#3
Martina Lambertini, Federica Filippi, Alessandro Traniello Gradassi, Laura Magni, Emi Dika
No abstract text is available yet for this article.
December 2, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29203105/bartonella-infection-in-asymptomatic-horses-and-donkeys-from-tuscany-central-italy
#4
Edoardo Magni, Fabrizio Bertelloni, Micaela Sgorbini, Valentina V Ebani
OBJECTIVE: To investigate the occurrence of Bartonella sp. infection in asymptomatic horses and donkeys living in Tuscany, Central Italy. METHODS: Blood samples were collected from 77 horses and 15 donkeys and tested by indirect immunofluorescent test to detect antibodies against Bartonella sp. and by PCR to detect the pathogen. RESULTS: Fifty-four (58.69%; 95% CI: 47.95%-68.87%) animals, 9 donkeys and 45 horses, were seropositive with antibody titers ranging from 1:64 to 1:512...
November 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29194486/cortical-auditory-evoked-responses-in-preterm-neonates-revisited-by-spectral-and-temporal-analyses
#5
A Kaminska, V Delattre, J Laschet, J Dubois, M Labidurie, A Duval, A Manresa, J-F Magny, S Hovhannisyan, M Mokhtari, L Ouss, A Boissel, L Hertz-Pannier, M Sintsov, M Minlebaev, R Khazipov, C Chiron
Characteristic preterm EEG patterns of "Delta-brushes" (DBs) have been reported in the temporal cortex following auditory stimuli, but their spatio-temporal dynamics remains elusive. Using 32-electrode EEG recordings and co-registration of electrodes' position to 3D-MRI of age-matched neonates, we explored the cortical auditory-evoked responses (AERs) after 'click' stimuli in 30 healthy neonates aged 30-38 post-menstrual weeks (PMW). (1) We visually identified auditory-evoked DBs within AERs in all the babies between 30 and 33 PMW and a decreasing response rate afterwards...
August 11, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29194417/matrix-assisted-laser-desorption-ionisation-mass-spectrometry-imaging-in-the-study-of-gastric-cancer-a-mini-review
#6
REVIEW
Andrew Smith, Isabella Piga, Manuel Galli, Martina Stella, Vanna Denti, Marina Del Puppo, Fulvio Magni
Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide and the disease outcome commonly depends upon the tumour stage at the time of diagnosis. However, this cancer can often be asymptomatic during the early stages and remain undetected until the later stages of tumour development, having a significant impact on patient prognosis. However, our comprehension of the mechanisms underlying the development of gastric malignancies is still lacking. For these reasons, the search for new diagnostic and prognostic markers for gastric cancer is an ongoing pursuit...
December 1, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29176773/reflectance-absorbance-and-transmittance-spectra-of-bermudagrass-and-manilagrass-turfgrass-canopies
#7
Marco Volterrani, Alberto Minelli, Monica Gaetani, Nicola Grossi, Simone Magni, Lisa Caturegli
Leaves act as a primary organ for the interception of solar radiation and their spatial arrangement determines how the plant canopy interacts with light. Many studies have been carried out on the penetration of radiation into crops however to date, few results are available on turfgrasses, mainly due to the difficulties of introducing sensors into the turf without disturbing the natural position of the leaves. In the present research two warm season turfgrasses, hybrid bermudagrass (Cynodon dactylon × transvaalensis) 'Patriot' and manilagrass (Zoysia matrella) 'Zeon', were studied...
2017: PloS One
https://www.readbyqxmd.com/read/29164325/effects-of-recreational-football-on-women-s-fitness-and-health-adaptations-and-mechanisms
#8
REVIEW
Peter Krustrup, Eva Wulff Helge, Peter R Hansen, Per Aagaard, Marie Hagman, Morten B Randers, Maysa de Sousa, Magni Mohr
The review describes the fitness and health effects of recreational football in women aged 18-65 years. The review documents that 2 × 1 h of recreational football training for 12-16 weeks causes marked improvements in maximal oxygen uptake (5-15%) and myocardial function in women. Moreover, mean arterial blood pressure was shown to decrease by 2-5 mmHg in normotensive women and 6-8 mmHg in hypertensive women. This review also show that short-term (< 4 months) and medium-term (4-16 months) recreational football training has major beneficial impact on metabolic health profile in women, with fat losses of 1-3 kg and improvements in blood lipid profile...
November 21, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29153332/sensorimotor-performance-and-function-in-people-with-osteoarthritis-of-the-hand-a-case-control-comparison
#9
Nicoló Edoardo Magni, Peter John McNair, David Andrew Rice
OBJECTIVES: To determine whether hand left/right judgements, tactile acuity, and body perception are impaired in people with hand OA. To examine the relationships between left right judgements, tactile acuity and hand pain. To explore the relationships between sensorimotor measures (left/right judgements and tactile acuity) and measures of hand function in people with hand OA. METHODS: Twenty patients with symptomatic hand OA and 19 healthy pain-free controls undertook a hand left/right judgment task, a control left/right judgement task, two-point discrimination (TPD) threshold testing (assessing tactile acuity), a neglect-like symptoms questionnaire (assessing body perception) and several established measures of hand function...
September 25, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29136806/multivariate-analysis-of-organic-acids-in-fermented-food-from-reversed-phase-high-performance-liquid-chromatography-data
#10
Pablo Mortera, Federico A Zuljan, Christian Magni, Santiago A Bortolato, Sergio H Alarcón
Multivariate calibration coupled to RP-HPLC with diode array detection (HPLC-DAD) was applied to the identification and the quantitative evaluation of the short chain organic acids (malic, oxalic, formic, lactic, acetic, citric, pyruvic, succinic, tartaric, propionic and α-cetoglutaric) in fermented food. The goal of the present study was to get the successful resolution of a system in the combined occurrence of strongly coeluting peaks, of distortions in the time sensors among chromatograms, and of the presence of unexpected compounds not included in the calibration step...
February 1, 2018: Talanta
https://www.readbyqxmd.com/read/29125829/bee-or-wasp-sting
#11
Kam Lun Hon, Alexander K C Leung
While jogging in a local park in Hong Kong, a 55-year-old, previously healthy man was stung on the ventral aspect of his right wrist. The tiny stinger was gently removed with nail cutters and examined under a microscope at 80x magni cation; plucking the stinger is ill- advised as this may inject more venom into the wounded site. Two days after stinging, the microscopic appearance of the stinger con rmed the diagnosis to be from a bee instead of a wasp or other insect. A simple method of con rming the nature of insect stings and an overview of Hymenoptera stings and their management are provided herein...
September 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29119246/skeletal-muscle-and-performance-adaptations-to-high-intensity-training-in-elite-male-soccer-players-speed-endurance-runs-versus-small-sided-game-training
#12
Dan Fransson, Tobias Schmidt Nielsen, Karl Olsson, Tobias Christensson, Paul S Bradley, Ioannis G Fatouros, Peter Krustrup, Nikolai Baastrup Nordsborg, Magni Mohr
PURPOSE: To examine the skeletal muscle and performance responses across two different exercise training modalities which are highly applied in soccer training. METHODS: Using an RCT design, 39 well-trained male soccer players were randomized into either a speed endurance training (SET; n = 21) or a small-sided game group (SSG; n = 18). Over 4 weeks, thrice weekly, SET performed 6-10 × 30-s all-out runs with 3-min recovery, while SSG completed 2 × 7-9-min small-sided games with 2-min recovery...
November 8, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29108406/intracerebral-hemorrhage-in-intensive-care-unit-early-prognostication-fallacies-a-single-center-retrospective-study
#13
Stefano Spina, Chiara Marzorati, Alessia Vargiolu, Federico Magni, Matteo Riva, Matteo Rota, Carlo Giussani, Erik P Sganzerla, Giuseppe Citerio
BACKGROUND: Intracerebral hemorrhage (ICH) admitted to intensive care is deem of poor prognosis. To compare observed and predicted 30-days mortality and to evaluate long term functional outcome in a consecutive ICH cohort. METHODS: Retrospective analysis of prospectively collected data of ICH patients managed in a Neuro-ICU from 2012 to 2015. RESULTS: 136 consecutive patients; 34 (25%) had "withholding of life-sustaining treatment" (WLST) order and 102 (75%) received a "full treatment" (FT)...
November 6, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29091412/coupling-of-zinc-porphyrin-dyes-and-copper-electrolytes-a-springboard-for-novel-sustainable-dye-sensitized-solar-cells
#14
Alessia Colombo, Gabriele Di Carlo, Claudia Dragonetti, Mirko Magni, Alessio Orbelli Biroli, Maddalena Pizzotti, Dominique Roberto, Francesca Tessore, Elisabetta Benazzi, Carlo Alberto Bignozzi, Laura Casarin, Stefano Caramori
The combination of β-substituted Zn(2+) porphyrin dyes and copper-based electrolytes represents a sustainable route for economic and environmentally friendly dye-sensitized solar cells. Remarkably, a new copper electrolyte, [Cu(2-mesityl-1,10-phenanthroline)2](+/2+), exceeds the performance reached by Co(2+/3+) and I(-)/I3(-) reference electrolytes.
November 1, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/29052802/the-development-of-episodic-future-thinking-in-middle-childhood
#15
F Ferretti, A Chiera, S Nicchiarelli, I Adornetti, R Magni, S Vicari, G Valeri, A Marini
The ability to imagine future events (episodic future thinking-EFT) emerges in preschoolers and further improves during middle childhood and adolescence. In the present study, we focused on the possible cognitive factors that affect EFT and its development. We assessed the ability to mentally project forward in time of a large cohort of 135 6- to 11-year-old children through a task with minimal narrative demands (the Picture Book Trip task adapted from Atance and Meltzoff in Cogn Dev 20(3):341-361. doi:10.1016/j...
October 20, 2017: Cognitive Processing
https://www.readbyqxmd.com/read/29048403/prenatal-factors-associated-with-neonatal-survival-of-infants-with-congenital-chylothorax
#16
M Dorsi, A Giuseppi, F Lesage, J Stirnemann, L De Saint Blanquat, M Nicloux, Z Assaf, N Khen Dunlop, E Kermorvant-Duchemin, J-F Magny, Y Ville, A Lapillonne
OBJECTIVES: Congenital chylothorax is a rare disease and prognostic factors are key element in properly informing parents. This study aimed at determining the prenatal factors associated with neonatal survival in a cohort of liveborn infants with congenital chylothorax. STUDY DESIGN: Observational monocentric cohort study including all liveborn neonates consecutively admitted for congenital chylothorax. RESULTS: Neonatal mortality was 32% (16/50)...
October 19, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29041832/enhanced-vitamin-b12-production-in-an-innovative-lupin-tempeh-is-due-to-synergic-effects-of-rhizopus-and-propionibacterium-in-cofermentation
#17
Camilla Signorini, Aristodemo Carpen, Luigi Coletto, Gigliola Borgonovo, Elisabetta Galanti, Jessica Capraro, Chiara Magni, Ambra Abate, Stuart K Johnson, Marcello Duranti, Alessio Scarafoni
Fermentation represents a valuable and cost-effective approach for food stabilisation and nutritional improvement. Tempeh is an example of soybean solid-state fermentation. In this work, we investigated the possibility of producing a tempeh analogue containing high amounts of vitamin B12 using seeds of three different species of the legume lupin, namely Lupinus albus, L. angustifolius and L. mutabilis, with Rhizopus oligosporus and Propionibacterium freudenreichii cofermentation. Synergic effects of Rhizopus and Propionibacterium in increasing vitamin B12 up to 1230 ng/g dw was observed...
October 18, 2017: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/29038365/muscle-ion-transporters-and-antioxidative-proteins-have-different-adaptive-potential-in-arm-than-in-leg-skeletal-muscle-with-exercise-training
#18
Magni Mohr, Tobias Schmidt Nielsen, Pál Weihe, Jákup A Thomsen, Giovanna Aquino, Peter Krustrup, Nikolai B Nordsborg
It was evaluated whether upper-body compared to lower-body musculature exhibits a different phenotype in relation to capacity for handling reactive oxygen species (ROS), H(+), La(-), Na(+), K(+) and also whether it differs in adaptive potential to exercise training. Eighty-three sedentary premenopausal women aged 45 ± 6 years (mean ± SD) were randomized into a high-intensity intermittent swimming group (HIS, n = 21), a moderate-intensity swimming group (MOS, n = 21), a soccer group (SOC, n = 21), or a control group (CON, n = 20)...
October 2017: Physiological Reports
https://www.readbyqxmd.com/read/29029560/failure-and-redemption-of-statistical-and-nonstatistical-rate-theories-in-the-hydroboration-of-alkenes
#19
Johnathan O Bailey, Daniel A Singleton
Our previous work found that canonical forms of transition state theory incorrectly predict the regioselectivity of the hydroboration of propene with BH3 in solution. In response, it has been suggested that alternative statistical and nonstatistical rate theories can adequately account for the selectivity. This paper uses a combination of experimental and theoretical studies to critically evaluate the ability of these rate theories, as well as dynamic trajectories and newly developed localized statistical models, to predict quantitative selectivities and qualitative trends in hydroborations on a broader scale...
October 26, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29029268/development-and-validation-of-a-method-for-the-detection-of-%C3%AE-and-%C3%AE-endosulfan-organochlorine-insecticide-in-calliphora-vomitoria-diptera-calliphoridae
#20
Paola A Magni, Marco Pazzi, Marco Vincenti, Valerio Converso, Ian R Dadour
Entomotoxicology studies employ analytical methods and instrumentation to detect chemical substances in carrion insects feeding from the decomposing tissues. The identification of such chemicals may determine the cause of death and may be used for the estimation of the minimum time since death. To date, the main focus of entomotoxicological studies has been the detection of drugs, whereas little information concerns the effects of pesticides on blowflies. Pesticides are generally freely available and more affordable than drugs but they can also be a home hazard and an accessible candidate poison at a crime scene...
October 4, 2017: Journal of Medical Entomology
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