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Magnesium AND supplement

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https://www.readbyqxmd.com/read/29225900/decreased-magnesium-status-may-mediate-the-increased-cardiovascular-risk-associated-with-calcium-supplementation
#1
EDITORIAL
James J DiNicolantonio, Mark F McCarty, James H O'Keefe
No abstract text is available yet for this article.
2017: Open Heart
https://www.readbyqxmd.com/read/29223451/mineralization-in-newborn-calves-contributes-to-health-improve-the-antioxidant-system-and-reduces-bacterial-infections
#2
Patrícia Glombowsky, Aleksandro S da Silva, Natan M Soldá, Gabriela M Galli, Angelisa H Biazus, Gabriela Campigotto, Nathieli B Bottari, Rejane S Sousa, Maiara C Brisola, Lenita M Stefani, Matheus D Baldissera, Marta L R Leal, Vera M Morsch, Maria Rosa C Schetinger, Gustavo Machado
The first phase of life of dairy calves has elevated mortality indices linked with low immunity and sanitary challenges, mainly bacterial infections are involved in the pathogenesis of diarrhea, the leading cause of death. Also, other important problem is the nutritional deficiencies, such as the mineral deficiency. Thus, the aim of this study was to evaluate whether an intramuscular mineral supplementation based on selenium, copper, potassium, magnesium and phosphorus possess beneficial effects on health of dairy calves...
December 6, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29211007/contribution-of-dietary-supplements-to-nutritional-adequacy-in-various-adult-age-groups
#3
Jeffrey B Blumberg, Balz Frei, Victor L Fulgoni, Connie M Weaver, Steven H Zeisel
Many Americans have inadequate intakes of several nutrients. The Dietary Guidelines for Americans 2015-2020 specifically identified vitamins A, C, D and E, calcium, magnesium, iron, potassium, choline and fiber as "underconsumed nutrients". Based on nationally representative data in 10,698 adults from National Health and Nutrition Examination Surveys (NHANES), 2009-2012, assessments were made of age-group differences in the impact of dietary supplements on nutrient intake and inadequacies. Compared to food alone, use of any dietary supplement plus food was associated with significantly (p < 0...
December 6, 2017: Nutrients
https://www.readbyqxmd.com/read/29206907/a-novel-bioactive-derivative-of-eicosapentaenoic-acid-epa-suppresses-intestinal-tumor-development-in-apc%C3%AE-14-mice
#4
Masako Nakanishi, Matthew P Hanley, Ruochen Zha, Yuichi Igarashi, Mark A Hull, Gary Mathias, Frank Sciavolino, James J Grady, Daniel W Rosenberg
Familial adenomatous polyposis (FAP) is a genetic disorder characterized by the development of hundreds of polyps throughout the colon. Without prophylactic colectomy, most individuals with FAP develop colorectal cancer at an early age. Treatment with eicosapentaenoic acid (EPA) in the free fatty acid form (EPA-FFA) has been shown to reduce polyp burden in FAP patients. Since high-purity EPA-FFA is subject to rapid oxidation, a stable form of EPA compound has been developed in the form of magnesium l-lysinate bis-eicosapentaenoate (TP-252)...
December 1, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/29198048/magnesium-in-breast-cancer-what-is-its-influence-on-the-progression-of-this-disease
#5
REVIEW
Priscyla Maria Vieira Mendes, Daila Leite Chaves Bezerra, Loanne Rocha Dos Santos, Raísa de Oliveira Santos, Stéfany Rodrigues de Sousa Melo, Jennifer Beatriz Silva Morais, Juliana Soares Severo, Sabas Carlos Vieira, Dilina do Nascimento Marreiro
Breast cancer is a disease of high mortality, characterized by the progressive accumulation of mutations that contribute to the uncontrolled development of breast tissue cells. Literature shows that disturbances in mineral homeostasis, such as magnesium, may interfere with tumor progression. The objective of this study is to provide updated information about magnesium's role in the pathogenesis of breast cancer. A review of literature was carried out from a search for articles in the PubMed and CAPES Periodicals databases published between 1995 and 2016 with the cross-references of the descriptors "magnesium," "breast neoplasms," and "oxidative stress" and the corresponding words in Portuguese...
December 2, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/29196879/the-feasibility-of-physiologically-based-pharmacokinetic-modeling-in-forensic-medicine-illustrated-by-the-example-of-morphine
#6
Nadine Schaefer, Daniel Moj, Thorsten Lehr, Peter H Schmidt, Frank Ramsthaler
In forensic medicine, expert opinion is often required concerning dose and time of intake of a substance, especially in the context of fatal intoxications. In the present case, a 98-year-old man died 4 days after admission to a hospital due to a femur neck fracture following a domestic fall in his retirement home. As he had obtained high morphine doses in the context of palliative therapy and a confusion of his supplemental magnesium tablets with a diuretic by the care retirement home was suspected by the relatives, a comprehensive postmortem examination was performed...
December 1, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29190155/purified-dry-paullinia-cupana-pc-18-extract-for-chemotherapy-induced-fatigue-results-of-two-double-blind-randomized-clinical-trials
#7
Claudia Vaz de Melo Sette, Bárbara Bonaparte Ribas de Alcântara, Jean Henri Maselli Schoueri, Felipe Melo Cruz, Daniel de Iracema Gomes Cubero, Luiz Francisco Pianowski, Luke Joseph Peppone, Fernando Fonseca, Auro Del Giglio
Fatigue is frequent among oncologic patients. Unpurified Paullinia cupana dry extract showed encouraging results for chemotherapy-induced fatigue in our previous studies. We report two randomized, double-blind studies with a standardized dry purified Paullinia cupana extract named PC-18. For both studies, we recruited early breast cancer patients who had an increase in their fatigue scores after their first cycle of adjuvant chemotherapy. In the first study, we compared an oral dose of 37.5 mg of PC-18 twice daily with placebo...
November 30, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29183350/sequential-activation-of-the-akt-pathway-in-human-osteoblasts-treated-with-oscarvit-a-bioactive-product-with-positive-effect-both-on-skeletal-pain-and-mineralization-in-osteoblasts
#8
Tibor Görögh, Elgar S Quabius, Alexander Georgitsis, Markus Hoffmann, Sebastian Lippross
BACKGROUND: Oscarvit (OSC) is an in-house preparation consisting of calcium, magnesium, phosphorus, strontium, Vitamin D, and eggshell membrane hydrolysate containing naturally occurring glycosaminoglycans and sulfated glycoproteins. OSC has been used both in an open-label human study and in vitro in osteoblasts. METHODS: Fifteen patients divided into three groups received oral OSC 0.6 g three times daily for 20 days. The main outcome measures were regional skeletal pain over the treatment period...
November 28, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29182799/inhaled-magnesium-sulfate-in-the-treatment-of-acute-asthma
#9
REVIEW
Rachel Knightly, Stephen J Milan, Rodney Hughes, Jennifer A Knopp-Sihota, Brian H Rowe, Rebecca Normansell, Colin Powell
BACKGROUND: Asthma exacerbations can be frequent and range in severity from mild to life-threatening. The use of magnesium sulfate (MgSO₄) is one of numerous treatment options available during acute exacerbations. While the efficacy of intravenous MgSO₄ has been demonstrated, the role of inhaled MgSO₄ is less clear. OBJECTIVES: To determine the efficacy and safety of inhaled MgSO₄ administered in acute asthma. SPECIFIC AIMS: to quantify the effects of inhaled MgSO₄ I) in addition to combination treatment with inhaled β₂-agonist and ipratropium bromide; ii) in addition to inhaled β₂-agonist; and iii) in comparison to inhaled β₂-agonist...
November 28, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29171639/nutritional-supplements-in-depressive-disorders
#10
Mónica Martínez-Cengotitabengoa, Ana González-Pinto
There is increasing evidence about the role of nutrients in mental health. An adequate intake of nutrients contributes to better overall health and mental health in particular. Major depression is a severe mental illness with a high prevalence for which effective treatments exist but not in all cases the patient’s remission is achieved. Therefore, it is increasingly aimed at optimizing the supply of nutrients necessary for adequate brain functioning as adjunctive therapy to antidepressant treatment in depressive disorders...
September 2017: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/29169161/digoxin-and-hypermagnesuria
#11
Luca Zanoli, Paolo Lentini, Pasquale Fatuzzo
In a recent issue of Nephron, Abu-Amer et al.[<xref ref-type="bibr" rid="ref1">1</xref>] reported the presence of hypermagnesuria in patients following acute intravenous administration of digoxin and suggested that the Na+/K+-ATPase γ-subunit, which is the pharmacological target of digoxin, can play a role in this process. Hypermagnesuria induced by digoxin may have important clinical consequences, particularly in the presence of inherited and acquired conditions associated with hypermagnesuria and hypomagnesemia...
November 23, 2017: Nephron
https://www.readbyqxmd.com/read/29160809/evaluation-of-dietary-intakes-and-supplement-use-in-paralympic-athletes
#12
Robyn F Madden, Jane Shearer, Jill A Parnell
Dietary intakes and supplement use in Paralympic athletes remains largely unexplored, and specialized recommendations are lacking. The aim of this study was to evaluate nutrient intakes and supplement use in high-performance athletes with physical disabilities using three-day food records and a validated dietary supplement use questionnaire. A secondary aim examined gender differences in nutrient and supplement intakes. Male (n = 18) and female (n = 22) athletes were recruited from nine Paralympic sports through sporting organizations, coaches, and social media...
November 21, 2017: Nutrients
https://www.readbyqxmd.com/read/29145756/micronutrients-and-natural-compounds-status-and-their-effects-on-wound-healing-in-the-diabetic-foot-ulcer
#13
Kanokwan Kulprachakarn, Sakaewan Ounjaijean, Jukkrit Wungrath, Raj Mani, Kittipan Rerkasem
The diabetic foot ulcer (DFU) is an invariably common complication of diabetes mellitus, it is also a significant cause of amputation as well as extended hospitalization. As most patients with DFU suffer from malnutrition, which has been related to improper metabolic micronutrients status, alterations can affect impaired wound healing process. Micronutrients and herbal remedies applications present a wide range of health advantages to patients with DFU. The purpose of this review is to provide current evidence on the potential effect of dietary supplementations such as vitamins A, C, D, E, magnesium, zinc, copper, iron, boron, and such naturally occurring compounds as Aloe vera, Naringin, and Radix Astragali (RA) and Radix Rehmanniae (RR) in the administration of lower extremity wounds, especially in DFU, and to present some insights for applications in the treatment of DFU patients in the future...
November 1, 2017: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/29142966/oral-magnesium-supplementation-in-chronic-kidney-disease-stages-3-and-4-efficacy-safety-and-effect-on-serum-calcification-propensity-a%C3%A2-prospective-randomized-double-blinded-placebo-controlled-clinical-trial
#14
Iain Bressendorff, Ditte Hansen, Morten Schou, Burton Silver, Andreas Pasch, Pierre Bouchelouche, Lise Pedersen, Lars Melholt Rasmussen, Lisbet Brandi
Introduction: Chronic kidney disease (CKD) is associated with high cardiovascular morbidity and mortality. Recent evidence suggests that increases in both serum and intracellular magnesium (Mg) can slow or even prevent the development of vascular calcification seen in CKD. Serum calcification propensity (T50) is a novel functional test, which is associated with all-cause mortality in CKD and measures the ability of serum to delay the formation of crystalline nanoparticles. Theoretically, increasing serum Mg should improve T50 and thereby reduce the propensity towards ectopic calcification...
May 2017: KI Reports
https://www.readbyqxmd.com/read/29137465/a-trial-on-the-effects-of-magnesium-zinc-calcium-vitamin-d-co-supplementation-on-glycemic-control-and-markers-of-cardio-metabolic-risk-in-women-with-polycystic-ovary-syndrome
#15
Mehri Jamilian, Maryam Maktabi, Zatollah Asemi
BACKGROUND: There is scarce data on the effects of magnesium-zinc-calcium-vitamin D co-supplementation on glycemic control and markers of cardio-metabolic risk among women with polycystic ovary syndrome (PCOS). The objective of this study was to assess the effects of magnesium-zinc-calcium-vitamin D co-supplementation on glycemic control and markers of cardio-metabolic risk in women with PCOS. METHODS: Sixty PCOS women were randomized into two groups and treated with 100 mg of magnesium, 4 mg of zinc, 400 mg of calcium plus 200 IU of vitamin D supplements (n = 30) or placebo (n = 30) twice a day for 12 weeks...
October 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29127547/the-effects-of-magnesium-and-zinc-co-supplementation-on-biomarkers-of-inflammation-and-oxidative-stress-and-gene-expression-related-to-inflammation-in-polycystic-ovary-syndrome-a-randomized-controlled-clinical-trial
#16
Faraneh Afshar Ebrahimi, Fatemeh Foroozanfard, Esmat Aghadavod, Fereshteh Bahmani, Zatollah Asemi
Magnesium and zinc are known to exert multiple beneficial effects including anti-inflammatory and antioxidant actions. To our knowledge, data on the effects of magnesium and zinc co-supplementation on biomarkers of inflammation and oxidative stress and gene expression related to inflammation in subjects of polycystic ovary syndrome (PCOS) are scarce. This study was conducted to evaluate the effects of magnesium and zinc co-supplementation on biomarkers of inflammation and oxidative stress and gene expression related to inflammation in subjects with PCOS...
November 10, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/29118161/dietary-nutrient-intake-ethnicity-and-epigenetic-silencing-of-lung-cancer-genes-detected-in-sputum-in-new-mexican-smokers
#17
Shuguang Leng, Maria A Picchi, Huining Kang, Guodong Wu, Piotr T Filipczak, Daniel E Juri, Xiequn Zhang, W James Gauderman, Frank D Gilliland, Steven A Belinsky
Lung cancer (LC) gene methylation detected in sputum assesses field cancerization and predicts LC incidence. Hispanic smokers have higher LC susceptibility compared to non-Hispanic Whites (NHW). We aimed to identify novel dietary nutrients affecting LC gene methylation and determine the degree of ethnic disparity in methylation explained by diet. Dietary intakes of 139 nutrients were assessed using a validated Harvard food frequency questionnaire in 327 Hispanics and 1502 NHWs from the Lovelace Smokers cohort (LSC)...
November 8, 2017: Cancer Prevention Research
https://www.readbyqxmd.com/read/29113038/micronutrient-dietary-intake-in-latina-pregnant-adolescents-and-its-association-with-level-of-depression-stress-and-social-support
#18
Angelie Singh, Caroline Trumpff, Jeanine Genkinger, Alida Davis, Marisa Spann, Elizabeth Werner, Catherine Monk
Adolescent pregnant women are at greater risk for nutritional deficits, stress, and depression than their adult counterparts, and these risk factors for adverse pregnancy outcomes are likely interrelated. This study evaluated the prevalence of nutritional deficits in pregnant teenagers and assessed the associations among micronutrient dietary intake, stress, and depression. One hundred and eight pregnant Latina adolescents completed an Automated Self-Administered 24-hour dietary recall (ASA24) in the 2nd trimester...
November 4, 2017: Nutrients
https://www.readbyqxmd.com/read/29102139/short-communication-supplementation-of-colostrum-and-milk-with-5-hydroxy-l-tryptophan-affects-immune-factors-but-not-growth-performance-in-newborn-calves
#19
Lorenzo E Hernández-Castellano, Ranya Özçelik, Laura L Hernandez, Rupert M Bruckmaier
In ruminants, colostrum is the main source of immunoglobulins for the newborn animal, conferring immune protection until the immune system becomes active and able to synthesize its own immunoglobulins. Serotonin (5-HT), a biogenic amine derived from tryptophan, has stimulatory effects on many physiological processes, including components of the innate (mastocytes, eosinophils, and natural killer cells) and adaptive (T and B lymphocytes) immune systems. Based on the known effects of 5-HT on the immune system, we hypothesized that increased concentrations of 5-HT, through administration of its precursor 5-hydroxy-l-tryptophan (5-HTP), may positively affect development of the calf's immune system and therefore support health and growth performance during the first weeks of life...
October 25, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29093983/the-importance-of-magnesium-in-clinical-healthcare
#20
REVIEW
Gerry K Schwalfenberg, Stephen J Genuis
The scientific literature provides extensive evidence of widespread magnesium deficiency and the potential need for magnesium repletion in diverse medical conditions. Magnesium is an essential element required as a cofactor for over 300 enzymatic reactions and is thus necessary for the biochemical functioning of numerous metabolic pathways. Inadequate magnesium status may impair biochemical processes dependent on sufficiency of this element. Emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for magnesium, a deficiency problem contributing to various health conditions...
2017: Scientifica
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