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https://www.readbyqxmd.com/read/29143590/exercise-therapy-in-multiple-sclerosis-and-its-effects-on-function-and-the-brain
#1
Ulrik Dalgas
Exercise therapy is a promising nonpharmacological therapy in people with multiple sclerosis (MS). Although exercise training may induce a transient worsening of symptoms in some MS patients, it is generally considered safe and does not increase the risk of relapses. Exercise training can lead to clinically relevant improvements in physical function, but should be considered an adjunct to specific task-based training. Exercise has also shown positive effects on the brain, including improvements in brain volume and cognition...
November 2017: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/29141966/nutritional-factors-affecting-adult-neurogenesis-and-cognitive-function
#2
REVIEW
Shibu M Poulose, Marshall G Miller, Tammy Scott, Barbara Shukitt-Hale
Adult neurogenesis, a complex process by which stem cells in the hippocampal brain region differentiate and proliferate into new neurons and other resident brain cells, is known to be affected by many intrinsic and extrinsic factors, including diet. Neurogenesis plays a critical role in neural plasticity, brain homeostasis, and maintenance in the central nervous system and is a crucial factor in preserving the cognitive function and repair of damaged brain cells affected by aging and brain disorders. Intrinsic factors such as aging, neuroinflammation, oxidative stress, and brain injury, as well as lifestyle factors such as high-fat and high-sugar diets and alcohol and opioid addiction, negatively affect adult neurogenesis...
November 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/29139007/adding-high-intensity-interval-training-to-conventional-training-modalities-optimizing-health-related-outcomes-during-chemotherapy-for-breast-cancer-the-optitrain-randomized-controlled-trial
#3
Sara Mijwel, Malin Backman, Kate A Bolam, Anna Jervaeus, Carl Johan Sundberg, Sara Margolin, Maria Browall, Helene Rundqvist, Yvonne Wengström
PURPOSE: Exercise training is an effective and safe way to counteract cancer-related fatigue (CRF) and to improve health-related quality of life (HRQoL). High-intensity interval training has proven beneficial for the health of clinical populations. The aim of this randomized controlled trial was to compare the effects of resistance and high-intensity interval training (RT-HIIT), and moderate-intensity aerobic and high-intensity interval training (AT-HIIT) to usual care (UC) in women with breast cancer undergoing chemotherapy...
November 14, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29136750/-a-perspective-cohort-study-on-influence-factors-of-survival-outcome-among-the-elderly-aged-%C3%A2-80-years-old-from-longevity-areas-in-china
#4
Y B Lyu, J Zhang, J S Luo, W H Shi, Z X Yin, L Q Su, J L Fang, J N Wang, X M Shi
Objective: To investigate the influence factors of survival outcome among elderly aged ≥80 years old. Methods: In baseline survey in 2009, 930 participants aged ≥80 years old were enrolled from 7 longevity areas, to collect the information of socioeconomic factors, life style, cognitive function, activities of daily living and diseases, as well as physical examination to test biomarkers of blood and urine. The survival status was followed up at 2012 and 2014 survey. Stepwise Cox proportional hazards models were used to screen influence factors of 5-year survival...
November 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29136483/fitness-sleep-disordered-breathing-symptoms-of-depression-and-cognition-in-inactive-overweight-children-mediation-models
#5
Monika M K Stojek, Amanda K Montoya, Christopher F Drescher, Andrew Newberry, Zain Sultan, Celestine F Williams, Norman K Pollock, Catherine L Davis
OBJECTIVES: We used mediation models to examine the mechanisms underlying the relationships among physical fitness, sleep-disordered breathing (SDB), symptoms of depression, and cognitive functioning. METHODS: We conducted a cross-sectional secondary analysis of the cohorts involved in the 2003-2006 project PLAY (a trial of the effects of aerobic exercise on health and cognition) and the 2008-2011 SMART study (a trial of the effects of exercise on cognition). A total of 397 inactive overweight children aged 7-11 received a fitness test, standardized cognitive test (Cognitive Assessment System, yielding Planning, Attention, Simultaneous, Successive, and Full Scale scores), and depression questionnaire...
November 2017: Public Health Reports
https://www.readbyqxmd.com/read/29136094/effects-of-multidomain-lifestyle-intervention-omega-3-supplementation-or-their-combination-on-physical-activity-levels-in-older-adults-secondary-analysis-of-the-multidomain-alzheimer-preventive-trial-mapt-randomised-controlled-trial
#6
Philipe de Souto Barreto, Yves Rolland, Matteo Cesari, Charlotte Dupuy, Sandrine Andrieu, Bruno Vellas
Background/objectives: to investigate the effects of a 3-year multidomain lifestyle intervention, omega-3 supplementation or both on physical activity (PA) in older adults with subjective memory complaints. Design/settings/subjects: the Multidomain Alzheimer Preventive Trial was a 3-year randomised controlled trial that enroled 1,680 community-dwelling adults aged 70 years or over, with subjective memory complaints. Participants were randomised to omega-3 supplementation (total daily dose of 800 mg docosahexanoic acid and up to 225 mg eicosapentanoic acid), multidomain intervention (nutritional and exercise counselling and cognitive training), omega-3 plus multidomain intervention or placebo with usual care...
November 10, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29135639/sleep-and-athletic-performance
#7
Andrew M Watson
Sleep is an essential component of health and well-being, with significant impacts on physical development, emotional regulation, cognitive performance, and quality of life. Along with being an integral part of the recovery and adaptive process between bouts of exercise, accumulating evidence suggests that increased sleep duration and improved sleep quality in athletes are associated with improved performance and competitive success. In addition, better sleep may reduce the risk of both injury and illness in athletes, not only optimizing health but also potentially enhancing performance through increased participation in training...
November 2017: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/29135358/training-area-agencies-on-aging-case-managers-to-improve-physical-function-mood-and-behavior-in-persons-with-dementia-and-caregivers-examples-from-the-rdad-northwest-study
#8
Susan M McCurry, Rebecca G Logsdon, Kenneth C Pike, David M LaFazia, Linda Teri
The Reducing Disability in Alzheimer's Disease (RDAD) program has been shown to be an effective tool for teaching caregivers strategies to improve mood, behavior, and physical function in persons with dementia. This paper describes how RDAD has been translated and implemented for use by Area Agencies on Aging (AAA) case managers across Washington and Oregon. Modifications to the original RDAD program as part of its community translation included decreasing the number of in-person sessions while preserving all educational content; involving caregivers in exercise activities for themselves as well as acting as exercise coaches for care-receivers; and enrolling persons with cognitive impairment due to mixed etiologies...
November 14, 2017: Journal of Gerontological Social Work
https://www.readbyqxmd.com/read/29131814/effects-of-an-exercise-protocol-for-improving-handgrip-strength-and-walking-speed-on-cognitive-function-in-patients-with-chronic-stroke
#9
Jaeeun Kim, Jongeun Yim
BACKGROUND Handgrip strength and walking speed predict and influence cognitive function. We aimed to investigate an exercise protocol for improving handgrip strength and walking speed, applied to patients with chronic stroke who had cognitive function disorder. MATERIAL AND METHODS Twenty-nine patients with cognitive function disorder participated in this study, and were randomly divided into one of two groups: exercise group (n=14) and control group (n=15). Both groups underwent conventional physical therapy for 60 minutes per day...
November 13, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29130020/what-do-we-know-from-clinical-trials-on-exercise-and-alzheimer-s-disease
#10
Yong Shen, Rena Li
Alzheimer's disease (AD) is the most common form of dementia in elderly with major symptoms of a general term for memory loss and other intellectual abilities impairment which are serious enough to interfere with daily life. While there is no treatment can prevent and revise the cognitive function impairment in AD, physical activity becomes a potential beneficial intervention for AD. Multiple evidences suggested that exercise in general plays beneficial roles in improving brain function. Most common mechanisms of exercise-induced enhancement of brain function are including alteration of neurogenesis, neuron plasticity, neuronal signaling and receptors, as well as neuronal networks...
December 2016: Journal of Sport and Health Science
https://www.readbyqxmd.com/read/29128777/a-systematic-review-of-heart-failure-dyadic-self-care-interventions-focusing-on-intervention-components-contexts-and-outcomes
#11
REVIEW
Harleah G Buck, Anna Stromberg, Misook L Chung, Kristine A Donovan, Karen Harkness, Allison M Howard, Naoko Kato, Randall Polo, Lorraine S Evangelista
BACKGROUND: Having support from an informal carer is important for heart failure patients. Carers have the potential to improve patient self-care. At the same time, it should be acknowledged that caregiving could affect the carer negatively and cause emotional reactions of burden and stress. Dyadic (patient and informal carer) heart failure self-care interventions seek to improve patient self-care such as adherence to medical treatment, exercise training, symptom monitoring and symptom management when needed...
October 19, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29127758/-physical-activity-the-holy-grail-of-modern-medicine
#12
Vladimír Tuka, Martina Daňková, Karel Riegel, Martin Matoulek
Movement is the basic attribute of life. It is not surprising that the return to regular physical activity is a very effective and cheap means of preventing and treating most non-cummunicable diseases. Therefore, every physician should be able to prescribe a suitable physical activity. The minimum amount of physical activity with proven effects in primary prevention of chronic diseases is relatively low: 150 minutes of moderate physical activity or 75 minutes of high intensity exercise per week or a combination of the two...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29126338/effect-of-neuromuscular-electrical-stimulation-on-brain-derived-neurotrophic-factor
#13
Toshiaki Miyamoto, Keihou Kou, Hideya Yanamoto, Saya Hashimoto, Mai Ikawa, Takashi Sekiyama, Yoshiki Nakano, Shin-Ichiro Kashiwamura, Chisako Takeda, Hiroyuki Fujioka
Brain-derived neurotrophic factor (BDNF) has been considered an essential mediator responsible for the beneficial effects of physical activity in preventing cognitive impairment. This study aimed at examining the effects of a single bout of neuromuscular electrical stimulation (NMES) on levels of BDNF in the plasma and on cognitive performance in healthy adult men. Thirteen healthy adult men participated in three experimental sessions. The first session was 30 min of NMES to both legs, the second was 30 min of cycling exercise at the intensity of 60% peak oxygen uptake, and the third was 30 min of complete rest...
November 10, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29124324/the-effect-of-mental-fatigue-on-critical-power-during-cycling-exercise
#14
Hawbeer Salam, Samuele M Marcora, James G Hopker
PURPOSE: Time to exhaustion (TTE) tests used in the determination of critical power (CP) and curvature constant (W') of the power-duration relationship are strongly influenced by the perception of effort (PE). This study aimed to investigate whether manipulation of the PE alters the CP and W'. METHODS: Eleven trained cyclists completed a series of TTE tests to establish CP and W' under two conditions, following a mentally fatiguing (MF), or a control (CON) task...
November 9, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29124115/study-protocol-of-the-intense-physical-activity-and-cognition-study-the-effect-of-high-intensity-exercise-training-on-cognitive-function-in-older-adults
#15
Belinda M Brown, Stephanie R Rainey-Smith, Natalie Castalanelli, Nicole Gordon, Shaun Markovic, Hamid R Sohrabi, Michael Weinborn, Simon M Laws, James Doecke, Kaikai Shen, Ralph N Martins, Jeremiah J Peiffer
Introduction: Inconsistent results from previous studies of exercise and cognitive function suggest that rigorously designed randomized controlled trials are urgently needed. Here, we describe the design of the Intense Physical Activity and Cognition (IPAC) study, which will assess the impact of a 6-month high-intensity exercise intervention on cognitive function and biomarkers of dementia risk, compared with a 6-month moderate-intensity exercise intervention and control group (no study-related exercise)...
November 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29121961/a-multicomponent-intervention-for-the-management-of-chronic-pain-in-older-adults-study-protocol-for-a-randomized-controlled-trial
#16
Sheung-Tak Cheng, Ka Long Chan, Rosanna W L Lam, Monique H T Mok, Phoon Ping Chen, Yu Fat Chow, Joanne W Y Chung, Alexander C B Law, Jenny S W Lee, Edward M F Leung, Cindy W C Tam
BACKGROUND: Studies have shown that physical interventions and psychological methods based on the cognitive behavioral approach are efficacious in alleviating pain and that combining both tends to yield more benefits than either intervention alone. In view of the aging population with chronic pain and the lack of evidence-based pain management programs locally, we developed a multicomponent intervention incorporating physical exercise and cognitive behavioral techniques and examined its long-term effects against treatment as usual (i...
November 9, 2017: Trials
https://www.readbyqxmd.com/read/29119954/-the-role-of-dosed-walking-in-the-combination-with-elements-of-cognitive-training-in-the-comprehensive-treatment-of-the-patients-presenting-with-alzheimer-s-disease
#17
N A Zimushkina, P V Kosareva, V G Cherkasova
AIM: The objective of the present study was to evaluate the effectiveness of dosed physical exercises for the combined treatment of the patients presenting with mild to moderate dementia associated with Alzheimer's disease (AD). MATERIAL AND METHODS: The comprehensive examination involved 41 patients (32 women and 9 men) with the confirmed diagnosis of 'probable' AD with stages 1 and 2 of dementia and 17 healthy volunteers comprising the group of comparison. In all the patients, the neurological examination was supplemented by neuropsychological testing...
2017: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/29115022/self-care-agency-lifestyle-and-physical-condition-predict-future-frailty-in-community-dwelling-older-people
#18
Chika Tanimura, Hiromi Matsumoto, Yasuko Tokushima, Junko Yoshimura, Shinji Tanishima, Hiroshi Hagino
The purpose of this 2 year longitudinal study was to identify the relationship between self-care agency, lifestyle, physical condition, and frailty among community-dwelling older people in a rural area of Japan. The participants were 133 older individuals aged 65 years or above. Data collection was conducted via face-to-face interviews using self-administered questionnaires. Background information, such as age, sex, current employment status, family structure, medication use, comorbidities, and knee and lower back pain, were assessed...
November 8, 2017: Nursing & Health Sciences
https://www.readbyqxmd.com/read/29114531/effects-of-a-short-term-detraining-period-on-muscle-functionality-and-cognition-of-strength-trained-older-women-a-preliminary-report
#19
Hélio José Coelho, Bruno Rodrigues, Ivan de Oliveira Gonçalves, Marco Carlos Uchida
The present study aimed to investigate the impact of a 1-month detraining composed by Christmas and New Year's Day in the functional and cognitive parameters of 12 older women who had previously participated in 22-week moderate intensity strength training program (ST; n=6) or remained performing their regular habits of life during all study period, without engaging in physical exercise programs (CG; n=6). Transfer capacity (i.e., Timed Up and Go [TUG]) and executive function (i.e., TUG with a cognitive task) were increased in the ST group after the intervention...
October 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29114500/analysis-of-energy-restriction-and-physical-activity-on-brain-function-the-role-of-ketone-body-and-brain-derived-neurotrophic-factor
#20
REVIEW
Chan Ho Park, Yi-Sub Kwak
Brain development is a complex process, and stimuli during this development period may modulate the functional maturation of the brain. It has been shown that environmental stimuli, such as physical activity habits, have a beneficial effect on brain development. Endurance exercise and prolonged fasting state are known to improve brain function including cognition. The exact mechanisms of exercise improving brain function are still unknown. However, it can be considered that energy restriction and stressful challenge induced by long-lasting physical exercise might cause direct effect on brain function...
August 2017: Journal of Exercise Rehabilitation
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