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https://www.readbyqxmd.com/read/29331329/terra-firma-forme-dermatosis
#1
Alexander K C Leung, Benjamin Barankin, Joseph M Lam
No abstract text is available yet for this article.
January 10, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29331013/epiploic-appendagitis
#2
Aimal Khan, Pak Shan Leung
No abstract text is available yet for this article.
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29330871/multi-site-n-glycan-mapping-study-2-uhplc
#3
Ákos Szekrényes, SungAe Suhr Park, Eoin Cosgrave, Aled Jones, Ted Haxo, Michael Kimzey, Shiva Pourkaveh, Zoltán Szabó, Zoran Sosic, Peng Feng, Preeti Sejwal, Kelsey Dent, David Michels, Gordon Freckleton, Jun Qian, Catherine Lancaster, Toni Duffy, Melissa Schwartz, Jiann-Kae Luo, Jonathan van Dyck, Pui-King Leung, Marcell Olajos, Ronald Kowle, Kai Gao, Wenbo Wang, Jo Wegstein, Samnang Tep, Apolka Domokos, Csaba Váradi, András Guttman
In the first part of this publication, the results from an international study evaluating the precision (i.e., repeatability and reproducibility) of N-glycosylation analysis using capillary electrophoresis of APTS-labeled N-glycans were presented. The corresponding results from ultra-high performance liquid chromatography (UHPLC) with fluorescence detection are presented here from 12 participating sites. All participants used the same lot of samples, reagents, and columns to perform the assays. Elution time, peak area and peak area percent values were determined for all peaks ≥0...
January 13, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29330238/changing-patterns-of-mental-health-care-use-the-role-of-integrated-mental-health-services-in-veteran-affairs-primary-care
#4
Lucinda B Leung, Jean Yoon, Lisa V Rubenstein, Edward P Post, Maureen E Metzger, Kenneth B Wells, Catherine A Sugar, José J Escarce
OBJECTIVE: Aiming to foster timely, high-quality mental health care for Veterans, VA's Primary Care-Mental Health Integration (PC-MHI) embeds mental health specialists in primary care and promotes care management for depression. PC-MHI and patient-centered medical home providers work together to provide the bulk of mental health care for primary care patients with low-to-moderate-complexity mental health conditions. This study examines whether increasing primary care clinic engagement in PC-MHI services is associated with changes in patient health care utilization and costs...
January 2018: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29329730/mechanical-thrombectomy-in-acute-ischaemic-stroke-a-review-of-the-different-techniques
#5
REVIEW
V Leung, A Sastry, S Srivastava, D Wilcock, A Parrott, S Nayak
Endovascular mechanical thrombectomy (MT) is reserved for acute ischaemic stroke secondary to large vessel occlusion. The various MT techniques employed in the treatment of hyperacute strokes are constantly evolving with new devices and improvisation of existing technology (Wahlgren, et al 2016). In this review, we describe a variety of MT techniques gained from our experience of performing over 350 procedures in 7 years of providing a 24/7 service within the national framework of a hyperacute stroke centre...
January 9, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29328515/magnetic-resonance-imaging-in-facioscapulohumeral-muscular-dystrophy
#6
EDITORIAL
Doris G Leung
No abstract text is available yet for this article.
January 12, 2018: Muscle & Nerve
https://www.readbyqxmd.com/read/29326401/efficacy-and-tolerability-of-trastuzumab-emtansine-in-advanced-human-epidermal-growth-factor-receptor-2-positive-breast-cancer
#7
W Yeo, M Y Luk, I S Soong, T Ys Yuen, T Y Ng, F Kf Mo, K Chan, S Y Wong, J Tsang, C Leung, J Js Suen, R Kc Ngan
INTRODUCTION: The management of human epidermal growth factor receptor 2 (HER2)-positive breast cancer has changed dramatically with the introduction and widespread use of HER2-targeted therapies. There is, however, relatively limited real-world information about the effectiveness and safety of trastuzumab emtansine (T-DM1) in the Hong Kong Chinese patients. We assessed the efficacy and toxicity profiles among local patients with HER2-positive advanced breast cancer who had received T-DM1 therapy in the second-line setting and beyond...
January 12, 2018: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/29325437/the-prevalence-and-burden-of-mental-and-substance-use-disorders-in-australia-findings-from-the-global-burden-of-disease-study-2015
#8
Liliana G Ciobanu, Alize J Ferrari, Holly E Erskine, Damian F Santomauro, Fiona J Charlson, Janni Leung, Azmeraw T Amare, Andrew T Olagunju, Harvey A Whiteford, Bernhard T Baune
OBJECTIVES: Timely and accurate assessments of disease burden are essential for developing effective national health policies. We used the Global Burden of Disease Study 2015 to examine burden due to mental and substance use disorders in Australia. METHODS: For each of the 20 mental and substance use disorders included in Global Burden of Disease Study 2015, systematic reviews of epidemiological data were conducted, and data modelled using a Bayesian meta-regression tool to produce prevalence estimates by age, sex, geography and year...
January 1, 2018: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/29325165/utilization-of-soy-hulls-oat-hulls-and-flax-meal-fiber-in-adult-broiler-breeder-hens
#9
H Leung, A Arrazola, S Torrey, E Kiarie
A total of 72, 65-week-old broiler breeder hens (Ross 308, BW 4,190 ± 45 g) was placed in individual cages to investigate utilization of fiber in soy hulls (SH), oat hulls (OH), and flax meal (FM). Birds were adapted to cages for 10 d prior to allocation (n = 18) to broiler breeder ration (control) or control mixed with either of the 3 fiber sources (wt/wt) added to supply equal amounts of neutral detergent fiber (NDF) ∼21% and TiO2. The daily feed allocation was based on 4% BW. Feed intake (FI) was monitored daily, and grab excreta samples were taken on d 16 and 17...
January 6, 2018: Poultry Science
https://www.readbyqxmd.com/read/29324695/investigation-into-improving-the-aqueous-solubility-of-the-thieno-2-3-b-pyridine-anti-proliferative-agents
#10
Ayesha Zafar, Lisa I Pilkington, Natalie A Haverkate, Michelle van Rensburg, Euphemia Leung, Sisira Kumara, William A Denny, David Barker, Ali Alsuraifi, Clare Hoskins, Jóhannes Reynisson
It is now established that the thieno[2,3-b]pyridines are a potent class of antiproliferatives. One of the main issues encountered for their clinical application is their low water solubility. In order to improve this, two strategies were pursued. First, a morpholine moiety was tethered to the molecular scaffold by substituting the sulphur atom with nitrogen, resulting in a 1H-pyrrolo[2,3-b]pyridine core structure. The water solubility was increased by three orders of magnitude, from 1.2 µg/mL (1-thieno[2,3-b]pyridine) to 1...
January 11, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29323215/green-tea-extract-attenuates-lps-induced-retinal-inflammation-in-rats
#11
Jia Lin Ren, Qiu Xiao Yu, Wei Cheng Liang, Pui Ying Leung, Tsz Kin Ng, Wai Kit Chu, Chi Pui Pang, Sun On Chan
Inflammation is in a wide spectrum of retinal diseases, causing irreversible blindness and visual impairment. We have previously demonstrated that Green Tea Extract (GTE) is a potent anti-inflammatory agent for anterior uveitis. Here we investigated the anti-inflammatory effect of GTE on lipopolysaccharides (LPS)-induced retinal inflammation in rats and explored the underlying mechanism. Adult rats were injected with LPS and GTE was administered intra-gastrically at 2, 8, 26 and 32 hours post-injection. Staining of whole-mount retina showed that the number of activated microglia cells was significantly increased at 48 hours post-injection, which was suppressed after GTE treatment in a dose-dependent manner...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29322276/integrating-direct-observation-and-gps-tracking-to-monitor-animal-behavior-for-resource-management
#12
Chelsey Walden-Schreiner, Yu-Fai Leung, Tim Kuhn, Todd Newburger
Monitoring the behavior of pack animals in protected areas informs management about use patterns and the potential associated negative impacts. However, systematic assessments of behavior are uncommon due to methodological and logistical constraints. This study integrated behavior mapping with GPS tracking, and applied behavior change point analysis, as an approach to monitor the behaviors of pack animals during overnight periods. The integrated approach identified multiple grazing patterns (i.e., locally intense grazing, ambulatory grazing) not feasible through a single methodology alone...
January 10, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29321869/imitating-the-cost-of-males-a-hypothesis-for-coexistence-of-all-female-sperm-dependent-species-and-their-sexual-host
#13
Christelle Leung, Bernard Angers
All-female sperm-dependent species are particular asexual organisms that must coexist with a closely related sexual host for reproduction. However, demographic advantages of asexual over sexual species that have to produce male individuals could lead both to extinction. The unresolved question of their coexistence still challenges and fascinates evolutionary biologists. As an alternative hypothesis, we propose those asexual organisms are afflicted by a demographic cost analogous to the production of males to prevent exclusion of the host...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29321643/magnetoelectricity-of-cofe2o4-and-tetragonal-phase-bifeo3-nanocomposites-prepared-by-pulsed-laser-deposition
#14
Min Gao, Ravindranath Viswan, Xiao Tang, Chung Ming Leung, Jiefang Li, D Viehland
The coupling between the tetragonal phase (T-phase) of BiFeO3 (BFO) and CoFe2O4 (CFO) in magnetoelectric heterostructures has been studied. Bilayers of CFO and BFO were deposited on (001) LaAlO3 single crystal substrates by pulsed laser deposition. After 30 min of annealing, the CFO top layer exhibited a T-phase-like structure, developing a platform-like morphology with BFO. Magnetic hysteresis loops exhibited a strong thickness effect of the CFO layer on the coercive field, in particular along the out-of-plane direction...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29319407/malpractice-litigation-in-acute-stroke-care-where-are-we-now
#15
Gilberto Kk Leung, Gerard Porter
Acute stroke care has undergone momentous changes in recent years with the introduction of intravenous thrombolysis, mechanical thrombectomy and integrated stroke services. While these are welcome developments, they also carry unique medico-legal challenges. In 2015, a patient from Greater Manchester was awarded over £1 million in compensation after ambulance paramedics failed to admit her to a specialist unit. This paper explores the medico-legal implications of this first but over looked thrombolysis-related claim in the United Kingdom...
January 1, 2018: Medico-legal Journal
https://www.readbyqxmd.com/read/29318670/a-self-powered-and-flexible-organometallic-halide-perovskite-photodetector-with-very-high-detectivity
#16
Siu-Fung Leung, Kang-Ting Ho, Po-Kai Kung, Vincent K S Hsiao, Husam N Alshareef, Zhong Lin Wang, Jr-Hau He
Flexible and self-powered photodetectors (PDs) are highly desirable for applications in image sensing, smart building, and optical communications. In this paper, a self-powered and flexible PD based on the methylammonium lead iodide (CH3 NH3 PBI3 ) perovskite is demonstrated. Such a self-powered PD can operate even with irregular motion such as human finger tapping, which enables it to work without a bulky external power source. In addition, with high-quality CH3 NH3 PBI3 perovskite thin film fabricated with solvent engineering, the PD exhibits an impressive detectivity of 1...
January 10, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29318631/early-life-gut-microbiome-and-egg-allergy
#17
Mina Fazlollahi, Yoojin Chun, Alexander Grishin, Robert A Wood, A Wesley Burks, Peter Dawson, Stacie M Jones, Donald Y M Leung, Hugh A Sampson, Scott H Sicherer, Supinda Bunyavanich
BACKGROUND: Gut microbiota may play a role in egg allergy. We sought to examine the association between early-life gut microbiota and egg allergy. METHODS: We studied 141 children with egg allergy and controls from the multi-center Consortium of Food Allergy Research study. At enrollment (age 3 to 16 months), fecal samples were collected and clinical evaluation, egg specific IgE measurement, and egg skin prick test were performed. Gut microbiome was profiled by 16S rRNA sequencing...
January 10, 2018: Allergy
https://www.readbyqxmd.com/read/29317935/hypertension-canada-s-2017-guidelines-for-diagnosis-risk-assessment-prevention-and-treatment-of-hypertension-in-adults-for-pharmacists-an-update
#18
Sarah A Lamb, Yazid N Al Hamarneh, Sherilyn K D Houle, Alexander A Leung, Ross T Tsuyuki
No abstract text is available yet for this article.
January 2018: Canadian Pharmacists Journal: CPJ, Revue des Pharmaciens du Canada: RPC
https://www.readbyqxmd.com/read/29317635/publisher-correction-random-access-quantum-information-processors-using-multimode-circuit-quantum-electrodynamics
#19
R K Naik, N Leung, S Chakram, Peter Groszkowski, Y Lu, N Earnest, D C McKay, Jens Koch, D I Schuster
In the original version of this Article, the affiliation details for Peter Groszkowski and Jens Koch were incorrectly given as 'Department of Physics, University of Chicago, Chicago, IL, 60637, USA', instead of the correct 'Department of Physics and Astronomy, Northwestern University, Evanston, Illinois 60208, USA'. This has now been corrected in both the PDF and HTML versions of the Article.
January 9, 2018: Nature Communications
https://www.readbyqxmd.com/read/29311277/characterization-of-conserved-and-novel-septal-factors-in-mycobacterium-smegmatis
#20
Katherine J Wu, Jenna Zhang, Catherine Baranowski, Vivian Leung, E Hesper Rego, Yasu S Morita, Eric J Rubin, Cara C Boutte
Septation in bacteria requires coordinated regulation of cell wall biosynthesis and hydrolysis enzymes so that new septal cross-wall can be appropriately constructed without compromising the integrity of the existing cell wall. Bacteria with different modes of growth and different types of cell wall require different regulators to mediate cell growth and division processes. Mycobacteria have both a cell wall structure and mode of growth that are distinct from well-studied model organisms and use several different regulatory mechanisms...
January 8, 2018: Journal of Bacteriology
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