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EUS-FNA

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https://www.readbyqxmd.com/read/28321928/eus-evaluation-for-pancreatic-cysts-necessity-or-overkill
#1
REVIEW
Nonthalee Pausawasdi, Thawee Ratanachu-Ek
Incidental pancreatic cysts have been gradually more recognized in clinical practice due to an increased use of transabdominal ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI). These lesions consist of inflammatory cysts (pseudocysts) and pancreatic cystic neoplasms (PCNs) which have been classified as benign, pre-malignant and malignant. The diagnosis and management strategy of incidentally discovered pancreatic cysts can be challenging as the majority of them are PCNs and CT or MRI alone may not be sufficient to provide an accurate diagnosis...
March 21, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28302441/percutaneous-transhepatic-cholangiographic-endobiliary-forceps-biopsy-versus-endoscopic-ultrasound-fine-needle-aspiration-for-proximal-biliary-strictures-a-single-centre-experience
#2
Kayvan Mohkam, Yaseen Malik, Carlos Derosas, John Isaac, Ravi Marudanayagam, Homoyoon Mehrzad, Darius F Mirza, Paolo Muiesan, Keith J Roberts, Robert P Sutcliffe
BACKGROUND: Endoscopic ultrasound fine needle aspiration (EUS-FNA) and percutaneous transhepatic cholangiographic endobiliary forceps biopsy (PTC-EFB) are valid procedures for histological assessment of proximal biliary strictures (PBS), but their performances have never been compared. This study aimed to compare the diagnostic performance of these two techniques. METHOD: The diagnostic performances of EUS-FNA and PTC-EFB were compared in a retrospective cohort of patients assessed for PBS from 2011 to 2015 at a single tertiary centre...
March 13, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28300686/epidermoid-cyst-in-an-intra-pancreatic-accessory-spleen-diagnosed-by-typical-radiographic-images-and-eus-fna-findings-with-contrast-agent-with-video
#3
Kazuyuki Matsumoto, Hironari Kato, Hiroyuki Okada
No abstract text is available yet for this article.
March 11, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28299351/endoscopic-ultrasound-guided-tissue-sampling-of-small-subepithelial-tumors-of-the-upper-gastrointestinal-tract-with-a-22-gauge-core-biopsy-needle
#4
Christoph Schlag, Christoph Menzel, Manuela Götzberger, Simon Nennstiel, Peter Klare, Stefan Wagenpfeil, Roland M Schmid, Gregor Weirich, Stefan von Delius
Background and study aims The optimal approach to small subepithelial tumors (SETs) of the upper gastrointestinal tract remains inconclusive. The aim of this study was to evaluate endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) for less invasive tissue sampling of small SETs of the upper gastrointestinal tract. Patients and methods In this prospective observational study patients with small ( ≤ 3 cm) SETs of the upper gastrointestinal tract were eligible and underwent EUS-FNB with a 22-gauge core biopsy needle...
March 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28281172/needle-based-confocal-laser-endomicroscopy-for-evaluation-of-cystic-neoplasms-of-the-pancreas
#5
Abdurrahman Kadayifci, Mustafa Atar, Omer Basar, David G Forcione, William R Brugge
BACKGROUND: The accurate diagnosis of cystic neoplasms of the pancreas (CNP) with current diagnostic methods is limited. Endoscopic ultrasound (EUS)-guided needle-based confocal laser endomicroscopy (nCLE) is a new technique which can obtain images from the cyst wall during EUS-fine needle aspiration (EUS-FNA). The aim of this study was to assess the safety, feasibility, and diagnostic value of nCLE for CNP. METHODS: Patients who underwent EUS-FNA to evaluate a CNP larger than 2 cm were enrolled...
March 9, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28260012/novel-quantitative-analysis-of-the-s100p-protein-combined-with-endoscopic-ultrasound-guided-fine-needle-aspiration-cytology-in-the-diagnosis-of-pancreatic-adenocarcinoma
#6
Masafumi Chiba, Hiroo Imazu, Masayuki Kato, Keiichi Ikeda, Hiroshi Arakawa, Tomohiro Kato, Kazuki Sumiyama, Sadamu Homma
Specimens obtained with endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) are often tiny and fragmented leading to an inconclusive and doubtful diagnosis. To overcome the limitations of EUS-FNA in the cytological diagnosis of pancreatic adenocarcinoma (PCA), we evaluated whether quantification of the S100P protein combined with EUS-FNA reliably discriminated between PCA and benign pancreatic lesions (BPL). A high sensitivity sandwich ELISA for S100P protein was developed to aid in the detection of PCA in small samples obtained using EUS-FNA...
February 21, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28258621/eus-diagnosis-of-subepithelial-lesions
#7
REVIEW
Mitsuhiro Kida, Yusuke Kawaguchi, Eiji Miyata, Rikiya Hasegawa, Toru Kaneko, Hiroshi Yamauchi, Shuko Koizumi, Kosuke Okuwaki, Shiro Miyazawa, Tomohisa Iwai, Hidehiko Kikuchi, Maya Watanabe, Hiroshi Imaizumi, Wasaburo Koizumi
Using EUS, it is practicable to diagnose Subepithelial lesions (SEL) with originating layer, echo level, and internal echo pattern etc. Lipoma, lymphangioma, and cyst have characteristic features, therefore they have no need for EUS-FNA. Ectopic pancreases and glomus tumors, which are originated from 3(rd) and 4(th) layer, are frequently seen in the antrum. Although ectopic pancreases located in the fundus or body are large and originated from 3(rd) and 4(th) layer (thickening of 4(th) layer). Each Subepithelial lesions has each characteristic finding...
March 3, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28256149/long-standing-indeterminate-biliary-stricture-with-iterative-negative-tissue-sampling-revealed-as-cholangiocarcinoma-under-spyglasstm-cholangiocoscopy
#8
Andrés Figueroa Marrero, Carlos M Chavarría-Herbozo, Carlos de la Serna Higuera, Manuel Pérez-Miranda
Bile duct brush cytology, intraductal biopsy and EUS-FNA are all used to characterize biliary strictures, with suboptimal sensitivity. Surgical resection without confirmed malignancy is undesirable. Cholangioscopy with targeted biopsies appears to increase the diagnostic yield in indeterminate biliary strictures, but it is still considered optional.
March 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28255475/solid-pseudopapillary-neoplasm-of-the-pancreas-in-young-male-patients-three-case-reports
#9
Akira Aso, Eikichi Ihara, Kazuhiko Nakamura, Irina Sudovykh, Tetsuhide Ito, Masafumi Nakamura, Tetsuo Ikeda, Nobuyoshi Takizawa, Yoshinao Oda, Shuji Shimizu
A preoperative diagnosis of solid pseudopapillary neoplasms (SPNs) in young male patients is difficult to achieve using radiological images. We herein present three cases of young male patients with relatively small SPNs. Endoscopic ultrasound (EUS) showed well-encapsulated, smooth-surfaced, heterogeneous solid lesions in all patients, and all preoperative diagnoses were achieved by EUS-guided fine needle aspiration (EUS-FNA). The final pathological diagnosis after surgery was an SPN with a Ki-67 labeling index of <2%...
2017: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/28243046/single-dose-intra-procedural-ceftriaxone-during-endoscopic-ultrasound-fine-needle-aspiration-of-pancreatic-cysts-is-safe-and-effective-results-from-a-single-tertiary-center
#10
Amir Klein, Rose Qi, Shyam Nagubandi, Eric Lee, Vu Kwan
BACKGROUND: Endoscopic ultrasound (EUS) with fine-needle aspiration (FNA) is universally used for the investigation and diagnosis of pancreatic cystic lesions (PCL). Infectious complications following EUS-FNA of PCL are rare. Antibiotic prophylaxis to reduce the risk of infection is recommended; however, there is no consensus on the optimal regimen or route of administration. Potential advantages of a single-dose intravenous (IV) antibiotic over a prolonged oral regimen include simplicity, guaranteed delivery and fewer antibiotic related adverse events, but there are only limited data to support this...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28238191/two-cases-of-resectable-pancreatic-cancer-diagnosed-by-open-surgical-biopsy-after-endoscopic-ultrasound-fine-needle-aspiration-failed-to-yield-diagnosis-case-reports
#11
Reishi Toshiyama, Takehiro Noda, Hidetoshi Eguchi, Yoshifumi Iwagami, Daisaku Yamada, Tadafumi Asaoka, Hiroshi Wada, Koichi Kawamoto, Kunihito Gotoh, Yutaka Takeda, Masahiro Tanemura, Eiichi Morii, Koji Umeshita, Masaki Mori, Yuichiro Doki
BACKGROUND: Tumor biopsy for histological diagnosis is required preoperatively and before initiating chemotherapy or radiation therapy for patients with pancreatic cancer (Cancer of the Pancreas: Clinical Practice Guidelines, European Society for Medical Oncology). Endoscopic ultrasound fine-needle aspiration (EUS-FNA) is widely applied to obtain tissue samples for histological examination. However, in some cases, EUS-FNA cannot be performed safely or tissue samples are insufficient to establish a definitive diagnosis...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28218999/assessment-of-morbidity-and-mortality-associated-with-eus-guided-fna-for-pancreatic-cystic-lesions-a-system-review-and-meta-analysis
#12
REVIEW
Huiyun Zhu, Fei Jiang, Jianwei Zhu, Yiqi Du, Zhendong Jin, Zhaoshen Li
BACKGROUND AND AIM: With increased availability of imaging technology, detection of pancreatic cystic lesions (PCLs) is on the rise. Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) improves the diagnosis accuracy of PCLs. Systematic evaluation of morbidity and mortality associated with EUS-FNA for PCLs has not been performed. We conducted a systematic review and meta-analysis of morbidity and mortality associated with EUS-FNA. METHODS: A literature search for relevant English-language articles was conducted on PubMed and EMBASE databases...
February 20, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28218194/role-of-contrast-enhanced-endoscopic-ultrasound-in-lymph-nodes
#13
REVIEW
Michael Hocke, Andre Ignee, Christoph Dietrich
Diagnosing unclear lymph node (LN) enlargements in the mediastinum and abdomen is the most important indication of endoscopic ultrasound (EUS)-fine needle aspiration (FNA) after the diagnosis and treatment of pancreatic diseases. Investigating LNs in these areas can happen in different clinical settings. Mostly, it is the first modality in general LN diseases without any peripheral LN enlargements. On the other hand, it can be the question of LN involvement in a known or suspected primary tumor. Due to EUS-FNA cytology, those questions can be answered highly, accurately...
January 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28208006/comparison-of-histologic-core-portions-acquired-from-a-core-biopsy-needle-and-a-conventional-needle-in-solid-mass-lesions-a-prospective-randomized-trial
#14
Ban Seok Lee, Chang-Min Cho, Min Kyu Jung, Jung Sik Jang, Han Ik Bae
Background/Aims: The superiority of endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) over EUS-guided fine needle aspiration (EUS-FNA) remains controversial. Given the lack of studies analyzing histologic specimens acquired from EUS-FNB or EUS-FNA, we compared the proportion of the histologic core obtained from both techniques. Methods: A total of 58 consecutive patients with solid mass lesions were enrolled and randomly assigned to the EUS-FNA or EUS-FNB groups...
February 17, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28205397/pancreatic-involvement-by-metastasizing-neoplasms-as-determined-by-endoscopic-ultrasound-guided-fine-needle-aspiration-a-clinicopathologic-characterization
#15
Miroslav Sekulic, Khalid Amin, Tetyana Mettler, Lizette K Miller, Shawn Mallery, Jimmie Stewart
BACKGROUND: Pancreatic tumors often represent primary neoplasms, however organ involvement with metastatic disease can occur. The use of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) to determine the underlying pathology provides guidance of clinical management. METHODS: 25 cases were identified in a retrospective review of our institution's records from 2006 to 2016. Clinical parameters and prognosis are described. RESULTS: Metastatic lesions to the pancreas diagnosed by EUS-FNA accounted for 4...
February 16, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28198009/endoscopic-ultrasound-guided-fine-needle-aspirate-derived-preclinical-pancreatic-cancer-models-reveal-panitumumab-sensitivity-in-kras-wild-type-tumors
#16
William Berry, Elizabeth Algar, Beena Kumar, Christopher Desmond, Michael Swan, Brendan J Jenkins, Daniel Croagh
Pancreatic cancer (PC) is largely refractory to existing therapies used in unselected patient trials, thus emphasizing the pressing need for new approaches for patient selection in personalized medicine. KRAS mutations occur in 90% of PC patients and confer resistance to epidermal growth factor receptor (EGFR) inhibitors (e.g., panitumumab), suggesting that KRAS wild-type PC patients may benefit from targeted panitumumab therapy. Here, we use tumor tissue procured by endoscopic ultrasound-guided fine-needle aspirate (EUS-FNA) to compare the in vivo sensitivity in patient-derived xenografts (PDXs) of KRAS wild-type and mutant PC tumors to panitumumab, and to profile the molecular signature of these tumors in patients with metastatic or localized disease...
February 15, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28195251/endobronchial-ultrasound-needle-aspiration-and-endoscopic-ultrasound-fine-needle-aspiration-in-thoracic-diseases
#17
S Colella, P F Clementsen, C Gurioli, C H Gurioli, C Ravaglia, S Tomassetti, A Rossi, S Piciucchi, A Dubini, V Poletti
EBUS-TBNA and EUS-FNA are minimally invasive techniques rapidly gaining ground in the non-surgical invasive diagnostic approach to thoracic diseases due to their high accuracy and low morbidity and mortality compared to surgical techniques. Moreover, in the diagnosis and staging of lung cancer the combination of the two techniques is superior to either test alone. In this review we focus on the role of EBUS-TBNA and EUS-FNA in both malignant and non-malignant thoracic diseases.
June 2016: Pathologica
https://www.readbyqxmd.com/read/28160342/diagnostic-efficacy-of-liquid-based-cytology-for-solid-pancreatic-lesion-samples-obtained-with-endoscopic-ultrasound-guided-fine-needle-aspiration-a-propensity-score-matched-analysis
#18
Shinichi Hashimoto, Hiroki Taguchi, Michiyo Higashi, Kazuhito Hatanaka, Toshihiro Fujita, Hiromichi Iwaya, Junichi Nakazawa, Shiho Arima, Yuji Iwashita, Fumisato Sasaki, Yuichiro Nasu, Shuji Kanmura, Akio Ido
OBJECTIVES: There is a paucity of data on the diagnostic efficacy of liquid-based cytology (LBC) for pancreatic samples obtained by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). Using propensity score matching, we retrospectively analyzed the additional diagnostic value of LBC compared to a conventional Papanicolaou smear (CPS) for samples of solid pancreatic lesions obtained via EUS-FNA. METHODS: This cohort study included 126 matched patients who underwent initial EUS-FNA for solid pancreatic lesions between January 2009 and August 2014...
February 3, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28154274/pancreatic-metastasis-from-rectal-cancer-that-was-diagnosed-by-endoscopic-ultrasonography-guided-fine-needle-aspiration-eus-fna
#19
Itsuki Sano, Akio Katanuma, Kei Yane, Toshifumi Kin, Kazumasa Nagai, Hajime Yamazaki, Hideaki Koga, Koh Kitagawa, Kensuke Yokoyama, Satoshi Ikarashi, Kuniyuki Takahashi, Hiroyuki Maguchi, Yuko Omori, Toshiya Shinohara
Pancreatic metastasis from colorectal cancer is rare, and there have been only a few reports of its preoperative diagnosis by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) with immunohistochemical staining. We herein describe the case of a 77-year-old woman in whom a solitary mass in the pancreatic tail was detected 11 years after rectal cancer resection. The patient also had a history of pulmonary tumor resection. We performed EUS-FNA and a histopathological examination showed adenocarcinoma with CD20+, CD7-, and CDX2+ (similar to her rectal cancer)...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28151856/comparison-of-two-different-size-needles-in-endoscopic-ultrasound-guided-fine-needle-aspiration-for-diagnosing-solid-pancreatic-lesions-a-meta-analysis-of-prospective-controlled-trials
#20
Mei-Mei Xu, Hong-Yu Jia, Li-Li Yan, Shan-Shan Li, Yue Zheng
BACKGROUND: This meta-analysis aimed to provide a pooled analysis of prospective controlled trials comparing the diagnostic accuracy of 22-G and 25-G needles on endoscopic ultrasonography (EUS-FNA) of the solid pancreatic mass. METHODS: We established a rigorous study protocol according to Cochrane Collaboration recommendations. We systematically searched the PubMed and Embase databases to identify articles to include in the meta-analysis. Sensitivity, specificity, and corresponding 95% confidence intervals were calculated for 22-G and 25-G needles of individual studies from the contingency tables...
February 2017: Medicine (Baltimore)
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