Masaru Fukahori, Ken Kato, Hirokazu Taniguchi, Rie Ohtomo, Naoki Takahashi, Hirokazu Shoji, Satoru Iwasa, Yoshitaka Honma, Atsuo Takashima, Tetsuya Hamaguchi, Yasuhide Yamada, Yasuhiro Shimada, Yoshinori Ito, Jun Itami, Nobukazu Hokamura, Hiroyasu Igaki, Yuji Tachimori, Keisuke Miwa, Takuji Torimura, Narikazu Boku
Cervical esophageal squamous cell carcinoma (CESCC) is rare, accounting for 5% of all esophageal carcinomas. Several diagnostic and predictive markers have been studied. However, to the best of our knowledge, no biomarker is known to determine patient management except the clinical stage. The present study aimed to evaluate whether human papilloma virus (HPV) infection, epidermal growth factor receptor (EGFR) and its pathway-related gene mutations, known to be sensitive biomarkers of oropharyngeal carcinomas, could be used as biomarkers for the prediction of the prognosis of patients with CESCC...
February 2021: Molecular and Clinical Oncology