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Viral hepatitid

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https://www.readbyqxmd.com/read/27708965/viral-hepatitis-screening-guideline-before-biological-drug-use-in-rheumatic-patients
#1
Ömer Karadağ, Timuçin Kaşifoğlu, Birol Özer, Sabahattin Kaymakoğlu, Yeşim Kuş, Murat İnanç, Gökhan Keser, Sedat Kiraz
Biological drugs (tumor necrosis factor inhibitors, rituximab, tocilizumab, abatacept, and tofacitinib) are important treatment alternatives in rheumatology, particularly for resistant patients. However, they may cause hepatitis B virus (HBV) and hepatitis C virus (HCV) reactivation; for instance, HBV reactivation may occur in a patient who is an inactive hepatitis B surface antigen (HBsAg) carrier or who has resolved HBV infection. Therefore, the screening of patients before biological treatment and the application of a prophylactic treatment, particularly with respect to latent HBV infections, are recommended when necessary...
March 2016: European Journal of Rheumatology
https://www.readbyqxmd.com/read/27405219/-the-clinical-and-epidemiological-characteristics-of-malaria-concurrent-with-other-infections-and-invasions
#2
REVIEW
A V Kondrashin, A K Tokmalaev, E N Morozov, L F Morozova
The present review considers malaria infection concurrent with different species of helminths, bacterial and viral infections, as well as mixed malaria pathogens in the subtropical and tropical countries of the world, causing the clinical picture and epidemiological situation to be different. Malaria co-infections with different pathogenic micro-organisms, such as HIV, tuberculosis, viral hepatitides, and others, affect almost one third of the planet's population. It is known that people who are at risk for malaria may be also at risk for other parasitic and infectious diseases, most commonly helminthisms...
April 2016: Meditsinskaia Parazitologiia i Parazitarnye Bolezni
https://www.readbyqxmd.com/read/27403109/idiopathic-adulthood-ductopenia-it-is-out-there
#3
Mohammad Bilal, Ali Kazemi, Michael Babich
Idiopathic adulthood ductopenia (IAD) is a chronic cholestatic entity of unknown origin characterized by loss of inter-lobular bile ducts that was first described two decades ago. Although the diagnostic criteria have been described in detail, IAD continues to be a rare diagnosis. Our thorough literature search revealed less than a hundred cases of IAD reported. Here we present a 34-year-old female with no significant past history who was evaluated for persistent elevation of serum alkaline phosphate levels...
January 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27170397/acute-liver-failure-it-s-just-a-matter-of-cell-death
#4
Jan-Peter Sowa, Guido Gerken, Ali Canbay
BACKGROUND: Acute liver failure (ALF) is characterized by a sudden loss of hepatic function due to hepatocyte cell death and dysfunction in previously healthy individuals. The clinical presentation of ALF is associated with coagulopathy (international normalized ratio ≥1.5) and hepatic encephalopathy, although the latter may be less pronounced. Without appropriate and timely intensive care or liver transplantation (LTx), ALF will result in multi-organ failure and death. Various causes may induce ALF, with acetaminophen (APAP) intoxication and acute hepatitis B infection as most common causes in industrialized countries...
2016: Digestive Diseases
https://www.readbyqxmd.com/read/27170381/history-and-global-burden-of-viral-hepatitis
#5
Hubert E Blum
Between 1963 and 1989, 5 hepatotropic viruses have been discovered that are the major causes of viral hepatitides worldwide: hepatitis A virus, hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis delta virus and hepatitis E virus. Their epidemiology and pathogenesis have been studied in great detail. Furthermore, the structure and genetic organization of their DNA or RNA genome including the viral life cycle have been elucidated and have been successfully translated into important clinical applications, such as the specific diagnosis, therapy and prevention of the associated liver diseases, including liver cirrhosis and hepatocellular carcinoma (HCC)...
2016: Digestive Diseases
https://www.readbyqxmd.com/read/26824818/-efficacy-of-the-infusion-hepatotropic-drug-remaxol-in-the-pathogenetic-therapy-for-cirrhotic-stage-chronic-viral-hepatitides
#6
V V Stel'makh, V K Kozlov, V F Ivanova, I A Samusenko
AIM: To investigate the impact of therapy with the infusion hepatoprotector remaxol on liver function in cirrhosis in the outcome of chronic viral hepatitides (CVH): HCV, HBV, HCV+HBV, and HBV+HDV. SUBJECTS AND METHODS: Sixty-five patients aged 26 to 76 years, who had been diagnosed as having liver cirrhosis (LC) in the outcome of CVH: HCV, HBV, HCV+HBV, and HBV+HDV were examined. During infusion therapy, every day 32 cirrhotic patients in the outcome of CVH B or C received intravenous remaxol 400 ml in a jetwise manner once daily for 11 days...
2015: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/26745988/united-kingdom-national-guideline-on-the-management-of-the-viral-hepatitides-a-b-and-c-2015
#7
Gary Brook, Sanjay Bhagani, Ranjababu Kulasegaram, Adele Torkington, David Mutimer, Elizabeth Hodges, Louise Hesketh, Simon Farnworth, Verity Sullivan, Charles Gore, Emma Devitt, Ann K Sullivan
No abstract text is available yet for this article.
June 2016: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/26616402/sexually-transmitted-infections-and-viral-hepatitides-in-patients-presenting-for-non-occupational-hiv-post-exposure-prophylaxis-results-of-a-prospective-cohort-study
#8
Nirojini Sivachandran, Reed A C Siemieniuk, Pauline Murphy, Andrea Sharp, Christine Walach, Tania Placido, Isaac I Bogoch
Data evaluating the screening practices for viral hepatitides and sexually transmitted infections (STIs) in patients presenting for non-occupational HIV post-exposure prophylaxis (nPEP) care are limited. Screening practices and prevalences of viral hepatitides and STIs were evaluated in 126 patients presenting to a dedicated HIV prevention clinic for HIV nPEP. Three patients (2.4%) were diagnosed with chronic hepatitis C infection, 28 (22.2%) did not have surface antibodies in sufficient quantity to confer immunity to hepatitis B, and six (4...
November 2015: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/26358655/extra-hepatic-manifestations-associated-with-hepatitis-e-virus-infection-a-comprehensive-review-of-the-literature
#9
REVIEW
Fateh Bazerbachi, Samir Haffar, Sushil K Garg, John R Lake
BACKGROUND AND AIMS: Hepatitis E virus (HEV) infection is a significant public health problem that afflicts almost 20 million individuals annually and causes acute liver injury in 3.5 million, with approximately 56 000 deaths. As with other viral hepatitides, extra-hepatic manifestations could represent an important aspect of this infection. The spectrum of these manifestations is still emerging. Acute pancreatitis and neurological, musculoskeletal, hematological, renal, and other immune-mediated manifestations have been described...
February 2016: Gastroenterology Report
https://www.readbyqxmd.com/read/26308313/gallbladder-and-pancreas-in-henoch-sch%C3%A3-nlein-purpura-review-of-the-literature
#10
Rossana Helbling, Sebastiano A G Lava, Giacomo D Simonetti, Pietro Camozzi, Mario G Bianchetti, Gregorio P Milani
OBJECTIVE: Involvement of the pancreato-biliary system has been occasionally noted in Henoch-Schönlein purpura. Furthermore, cases of this vasculitis syndrome sometimes develop in the context of a viral hepatitis or after hepatitis vaccination. METHODS: We completed a review of the literature. RESULTS: Fifty reports published between 1977 and 2015 were retained for the analysis. A pancreato-biliary involvement was recognized in 34 individually well-described patients (♂:♀ = 19:15) with severe abdominal pain: pancreatitis (N = 20), acalculous cholecystitis (N = 11), both pancreatitis and cholecystitis (N = 3)...
March 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/26079666/seroprevalence-for-hepatitis-e-and-other-viral-hepatitides-among-diverse-populations-malawi
#11
Taha E Taha, Laura K Rusie, Alain Labrique, Mulinda Nyirenda, Dean Soko, Melvin Kamanga, Johnstone Kumwenda, Homayoon Farazadegan, Kenrad Nelson, Newton Kumwenda
Data on prevalence of hepatitis E virus (HEV) in Malawi is limited. We tested blood samples from HIV-uninfected and -infected populations of women and men enrolled in research studies in Malawi during 1989-2008 to determine the seroprevalence of HEV, hepatitis A virus (HAV), hepatitis B virus (HBV), and hepatitis C virus (HCV). Samples were tested for IgG against HEV, total antibodies against HAV and HCV, and presence of HBV surface antigens. Of 800 samples tested, 16.5% were positive for HEV IgG, 99.6% were positive for HAV antibodies, 7...
July 2015: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/25937863/progress-and-prospects-of-engineered-sequence-specific-dna-modulating-technologies-for-the-management-of-liver-diseases
#12
REVIEW
Samantha A Nicholson, Buhle Moyo, Patrick B Arbuthnot
Liver diseases are one of the leading causes of mortality in the world. The hepatic illnesses, which include inherited metabolic disorders, hemophilias and viral hepatitides, are complex and currently difficult to treat. The maturation of gene therapy has heralded new avenues for developing effective intervention for these diseases. DNA modification using gene therapy is now possible and available technology may be exploited to achieve long term therapeutic benefit. The ability to edit DNA sequences specifically is of paramount importance to advance gene therapy for application to liver diseases...
April 28, 2015: World Journal of Hepatology
https://www.readbyqxmd.com/read/25874513/redefining-the-alanine-aminotransferase-upper-limit-of-normal-improves-the-prediction-of-metabolic-syndrome-risk
#13
Martin Janičko, Eduard Veselíny, Radoslav Orenčák, Rastislav Husťak, Ján Fedačko, Sylvia Dražilová, Andrea Madarasová-Gecková, Mária Mareková, Daniel Pella, Pavol Kristián, Marek Rác, Peter Jarčuška
BACKGROUND: Multiple studies have recently proposed the lowering of upper limit of normal (ULN) for alanine aminotransferase (ALT) to improve the diagnostic sensitivity for viral hepatitides and metabolic syndrome (MS). We have tried to validate some of the proposed ULNs in the diagnosis of MS. METHODS: We used data from the HepaMeta Study conducted in 2011 in Slovakia, which explored the prevalence of MS in eastern Slovakia. Patients were tested for the criteria of MS and ALT...
April 2015: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/25509897/-the-problem-of-viral-hepatitis-c-in-the-russian-federation
#14
REVIEW
N D Iushchuk, O O Znoĭko, K R Dudina, P A Belyĭ
The incidence of chronic viral hepatitides (CVH) has increased 2.2-fold in the Russian Federation over the past decade. This increase is mainly determined by an almost threefold rise in the incidence of chronic hepatitis C (CHC): from 12.9 in 1999 to 39.1 per 100,000 population in 2012. The calculated data of hepatitis C burden in the Russian Federation show that in 2010 the total medical and social losses and expenses associated with hepatitis C and its implications were 48.47 billion rubles or 0.108% of the gross domestic product, the direct medical costs were 17...
2014: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/25399407/chemerin-as-a-novel-non-invasive-serum-marker-of-intrahepatic-lipid-content-in-obese-children
#15
Monika Kłusek-Oksiuta, Irena Bialokoz-Kalinowska, Eugeniusz Tarasów, Malgorzata Wojtkowska, Irena Werpachowska, Dariusz Marek Lebensztejn
BACKGROUND: Ectopic hepatic lipid accumulation is closely related to the development of insulin resistance, which is regarded as one of the most significant risk factors of non-alcoholic fatty liver disease (NAFLD). The current study has shown that fat tissue constitutes an important endocrine organ with its own production and metabolism of many biologically active substances, among which adipokines play an important role. Classic adipokines (e.g. leptin, adiponectin, resistin) are fat-derived hormones which serum level is altered in patients with NAFLD...
2014: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/25011557/aflatoxin-exposure-may-not-play-a-role-in-liver-cancer-development-in-mongolia
#16
Walter Popp, Tsagaan Gantumur, Birgit Ross, Khand Zorigt, Duger Davaadorj, Michael Rossburg, Jan-Peter Sowa, Ali Canbay
BACKGROUND/AIMS: The incidence of hepatocellular carcinoma (HCC) in Mongolia is growing at an alarming rate. Traditional dried food was suggested as the major reason for high HCC numbers, due to possible aflatoxin contamination during manufacturing. We thus aimed to measure aflatoxin concentrations in Mongolian food samples. METHODS: Samples of traditional Mongolian food ('aaruul', dried meat, and dried noodles; in total 11 samples) were collected and shipped to Germany...
2014: Digestion
https://www.readbyqxmd.com/read/24984326/-epidemiology-of-viral-hepatitis
#17
Bernard Kaić, Tatjana Vilibić-Cavlek, Sanja Kurecić Filipović, Tatjana Nemeth-Blazić, Iva Pem-Novosel, Vesna Visekruna Vucina, Aleksandar Simunović, Martina Zajec, Ivan Radić, Jasmina Pavlić, Marica Glamocanin, Ira Gjenero-Margan
Understanding the country-specific epidemiology of disease, which may vary greatly among countries, is crucial for identifying the most appropriate preventive and control measures. An overview of the local epidemiology of viral hepatitis in Croatia is given in this paper. The overall prevalence of hepatitis B in Croatia is low (less than 2% HBsAg carriers in the general population). Hepatitis B incidence and prevalence began to decline significantly following the introduction of universal hepatitis B vaccination in 1999...
October 2013: Acta Medica Croatica: C̆asopis Hravatske Akademije Medicinskih Znanosti
https://www.readbyqxmd.com/read/24964536/-viral-hepatitides-b-and-c-medical-progress-versus-economic-difficulties
#18
Jean-Yves Nau
No abstract text is available yet for this article.
May 28, 2014: Revue Médicale Suisse
https://www.readbyqxmd.com/read/24806904/fluoroplast-polyaniline-coated-adsorbent-for-one-step-isolation-of-dna-for-pcr-detection-of-viral-hepatitides-hbv-and-ttv
#19
Dmitry V Kapustin, Anna I Prostyakova, Vitaly P Zubov
AIMS: To demonstrate the effectiveness of application of the adsorbent successively modified with nano-layers of fluoroplast and polyaniline for one-step isolation of DNA of hepatitis B virus and transfusion-transmitted virus from human serum. MATERIALS & METHODS: The technique is based on the application of the spin-cartridges containing porous adsorbent for one-step viral DNA isolation from serum followed by polymerase chain reaction. RESULTS: The developed adsorbent was shown to be effective for one-step isolation of viral DNA from serum samples for polymerase chain reaction diagnostics...
April 2014: Bioanalysis
https://www.readbyqxmd.com/read/24432592/-the-relevance-and-prospects-of-introducing-a-uniform-federal-register-of-patients-with-viral-hepatitis-b-and-c-in-russia
#20
EDITORIAL
(no author information available yet)
The article provides the current epidemiological characteristics of viral hepatitis B and C and the existing problems of registering parenteral viral hepatitides in Russia. It justifies the need for introducing a uniform federal registry of patients with viral hepatitis B and C and shows prospects for its introduction.
2013: Terapevticheskiĭ Arkhiv
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