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multichannel intraluminal impedance

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https://www.readbyqxmd.com/read/28235713/gastroesophageal-reflux-is-not-associated-with-short-term-variability-of-parasympathetic-activity-in-children
#1
Jan Krzysztof Nowak, Agata Łaźniak, Aleksandra Lisowska, Zdzisława Kycler, Waldemar Bobkowski, Jarosław Walkowiak
PURPOSE: A lower parasympathetic activity was described in patients with the gastroesophageal reflux disease. We aimed to determine whether gastroesophageal reflux (GER) episodes are associated with a short-term parasympathetic tone variability in children. METHODS: In order to address this question we performed simultaneous 24-h esophageal multichannel intraluminal impedance-pH and electrocardiographic monitoring in 16 children (age range 6-18 years), including 8 with asthma and 2 with gastroesophageal reflux disease...
February 21, 2017: Advances in Medical Sciences
https://www.readbyqxmd.com/read/28214352/gastro-oesophageal-reflux-in-patients-with-chronic-rhino-sinusitis-investigated-with-multichannel-impedance-ph-monitoring
#2
E J Katle, J G Hatlebakk, T Grimstad, J T Kvaløy, S K Steinsvåg
INTRODUCTION: The pathophysiology of chronic rhinosinusitis (CRS) is unclear. It has been discussed for decades whether gastro-oesophageal reflux (GOR) may be a contributing factor for some patients. The aim of the present study was to evaluate the level of GOR in an unselected group of patients with CRS using multichannel impedance-pH monitoring. METHODS: Consecutive patients with CRS diagnosed using the EPOS2012 criteria, completed questionnaires on GOR symptoms and were offered 24-h multichannel intraluminal impedance (MII)-pH monitoring...
March 1, 2017: Rhinology
https://www.readbyqxmd.com/read/28185711/impact-of-gastroesophageal-reflux-and-delayed-gastric-emptying-on-pediatric-lung-transplant-outcomes
#3
Fei Jamie Dy, Dawn Freiberger, Enju Liu, Debra Boyer, Gary Visner, Rachel Rosen
BACKGROUND: Gastroesophageal reflux disease is thought to predispose to adverse lung allograft outcomes. However, little is known about the burden of gastroesophageal reflux (GER) and gastroparesis in pediatric patients. In this study we describe the burden of reflux and gastroparesis in children undergoing lung transplant, and evaluates their impact on allograft survival and rejection incidence. METHODS: This study is a retrospective analysis of pediatric lung transplant recipients who had combined pH and multichannel intraluminal impedance testing (pH-MII) and gastric-emptying scans (GES)...
January 6, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28144844/surveillance-in-patients-with-esophageal-atresia-tracheoesophageal-fistula
#4
REVIEW
Arunjot Singh, William Middlesworth, Julie Khlevner
PURPOSE OF REVIEW: Esophageal atresia/tracheoesophageal fistula (EA/TEF) is a congenital aerodigestive anomaly with high survival rates after surgical repair. Care should now be focused on prevention of long-term complications using appropriate surveillance techniques. RECENT FINDINGS: The incidence of gastroesophageal reflux disease (GERD) is high in patients with EA/TEF. Consequences of untreated GERD include esophagitis, strictures, and Barrett esophagus. Subjective symptoms are an unreliable indicator of presence or severity of GERD, and therefore, diagnostic testing is needed to assess esophageal heath and monitor the effectiveness of anti-reflux treatment...
January 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28133879/normal-values-of-esophageal-pressure-responses-to-a-rapid-drink-challenge-test-in-healthy-subjects-results-of-a-multicenter-study
#5
I Marin, D Cisternas, L Abrao, E Lemme, C Bilder, A Ditaranto, R Coello, A Hani, A M Leguizamo, A Meixueiro, J Remes-Troche, M A Zavala, A Ruiz de León, J Perez de la Serna, M A Valdovinos, J Serra
BACKGROUND: Multiple water swallow is increasingly used as a complementary challenge test in patients undergoing high-resolution manometry (HRM). Our aim was to establish the range of normal pressure responses during the rapid drink challenge test in a large population of healthy subjects. METHODS: Pressure responses to a rapid drink challenge test (100 or 200 mL of water) were prospectively analyzed in 105 healthy subjects studied in nine different hospitals from different countries...
January 29, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28045635/association-between-laryngeal-pepsin-levels-and-the-presence-of-vocal-fold-polyps
#6
Lu Wang, Jia-Jie Tan, Ting Wu, Rui Zhang, Jia-Nuan Wu, Fang-Fang Zeng, You-Li Liu, Xiao-Yan Han, Yan-Fei Li, Xiang-Ping Li
Objective To determine whether pepsin, the main component of refluxed gastric contents, is significantly associated with vocal fold polyps and to evaluate the diagnostic value of pepsin in vocal fold polyps' tissues. Study Design Cross-sectional study. Setting Nanfang Hospital of Southern Medical University. Subjects and Methods The study included 32 patients with vocal fold polyps and 16 healthy controls between 2011 and 2012. Reflux symptom index and reflux finding score assessments, 24-hour combined multichannel intraluminal impedance and pH monitoring, and biopsy of the vocal fold polyp tissues or posterior laryngeal mucosa (healthy controls) for immunohistochemical pepsin staining were performed...
January 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28044052/the-relationship-of-the-post-reflux-swallow-induced-peristaltic-wave-index-and-esophageal-baseline-impedance-with-gastroesophageal-reflux-disease-symptoms
#7
Young Kyu Cho, Joon Seong Lee, Tae Hee Lee, Su Jin Hong, Sang Joon Park, Seong Ran Jeon, Hyun Gun Kim, Jin-Oh Kim
Background/Aims: The post-reflux swallow-induced peristaltic wave (PSPW) index and esophageal baseline impedance (BI) are novel impedance parameters used to evaluate esophageal chemical clearance and mucosal integrity. However, their relationship with reflux symptoms is not known. We aimed to evaluate the correlations of the PSPW index and esophageal BI with gastroesophageal reflux disease (GERD) symptoms. Methods: We performed a retrospective review of multichannel intraluminal impedance and pH (MII-pH) tracings in patients with suspected GERD...
January 2, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28028956/assessment-of-clinical-symptoms-and-multichannel-intraluminal-impedance-and-ph-monitoring-in-children-after-thoracoscopic-repair-of-esophageal-atresia-and-distal-tracheoesophageal-fistula
#8
Barbara M Iwańczak, Agnieszka Kosmowska-Miśków, Anna Kofla-Dłubacz, Mateusz Palczewski, Michał Grabiński, Katarzyna Pawłowska, Krzysztof Matusiewicz, Dariusz Patkowski
BACKGROUND: Motility disturbances of the esophagus and gastroesophageal reflux disease (GERD) are observed frequently in children after repair of congenital esophageal atresia with distal tracheoesophageal fistula (EA/TEF). Recently, in many pediatric surgical centers, thoracoscopic repair was introduced, which theoretically would change the postoperative course. OBJECTIVES: The goal of the study was to assess physical development, disease symptoms, and GERD symptom frequency in children who underwent thoracoscopic surgery of congenital EA/TEF...
September 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28004504/association-between-24-hour-combined-multichannel-intraluminal-impedance-ph-monitoring-and-symptoms-or-quality-of-life-in-patients-with-laryngopharyngeal-reflux
#9
S I Kim, O E Kwon, S Y Na, Y C Lee, J M Park, Y G Eun
OBJECTIVE: To evaluate the association between the parameters of 24-hour multichannel intraluminal impedance (MII)-pH monitoring and the symptoms or quality of life (QoL) in laryngopharyngeal reflux (LPR) patients. DESIGN: Prospective cohort study without controls. SETTING: University teaching hospital. METHODS: Forty-five LPR patients were selected from subjects who underwent 24-hour MII-pH monitoring and were diagnosed with LPR from September 2014 to May 2015...
December 22, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27987250/lung-disease-severity-in-idiopathic-pulmonary-fibrosis-is-more-strongly-associated-with-impedance-measures-of-bolus-reflux-than-ph-parameters-of-acid-reflux-alone
#10
S Gavini, L F Borges, R T Finn, W-K Lo, H J Goldberg, R Burakoff, N Feldman, W W Chan
BACKGROUND: Gastroesophageal reflux (GER) has been associated with idiopathic pulmonary fibrosis (IPF). Pathogenesis may be related to chronic micro-aspiration. We aimed to assess objective measures of GER on multichannel intraluminal impedance and pH study (MII-pH) and their relationship with pulmonary function testing (PFT) results, and to compare the performance of pH/acid reflux parameters vs corresponding MII/bolus parameters in predicting pulmonary dysfunction in IPF. METHODS: This was a retrospective cohort study of IPF patients undergoing prelung transplant evaluation with MII-pH off acid suppression, and having received PFT within 3 months...
December 16, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27984348/low-impedance-baseline-values-predict-severe-esophagitis
#11
Judith Cohen Sabban, Gabriela Donato Bertoldi, Federico Ussher, Silvia Christiansen, Carlos Lifschitz, Marina Orsi
OBJETIVES: To determine if esophageal baseline impedance (BI) values in children could be predictive of esophagitis. MATERIAL & METHODS: Multichannel intraluminal Impedance (MII) tracings of children 3 to 17 yrs of age suspected of having gastroesophageal reflux (GER) and esophagitis, who had also undergone upper endoscopy with multiple esophageal biopsies, were reviewed. Patients with eosinophilic esophagitis were excluded. Esophagitis was assessed by macroscopic and microscopic parameters...
December 15, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27979581/the-edematous-and-erythematous-airway-does-not-denote-pathologic-gastroesophageal-reflux
#12
Rachel Rosen, Paul D Mitchell, Janine Amirault, Manali Amin, Karen Watters, Reza Rahbar
OBJECTIVE: To determine if the reflux finding score (RFS), a validated score for airway inflammation, correlates with gastroesophageal reflux measured by multichannel intraluminal impedance (MII) testing, endoscopy, and quality of life scores. STUDY DESIGN: We performed a prospective, cross-sectional cohort study of 77 children with chronic cough undergoing direct laryngoscopy and bronchoscopy, esophagogastroduodenoscopy, and MII testing with pH (pH-MII) between 2006 and 2011...
December 13, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27920480/comparison-of-multichannel-intraluminal-impedance-ph-monitoring-and-reflux-scintigraphy-in-pediatric-patients-with-suspected-gastroesophageal-reflux
#13
Nuray Uslu Kızılkan, Murat Fani Bozkurt, Inci Nur Saltık Temizel, Hülya Demir, Aysel Yüce, Biray Caner, Hasan Özen
AIM: To evaluate the agreement of multichannel intraluminal impedance-pH monitoring (MII-pHM) and gastroesophageal reflux scintigraphy (GES) for the diagnosis of gastroesophageal reflux disease. METHODS: Seventy-five consecutive patients with suspected gastroesophageal reflux disease (GERD) underwent 24-h combined MII-pHM recording and one hour radionuclide scintigraphy during the course of the MII-pHM study. Catheters with 6 impedance channels and 1 pH sensor were placed transnasally...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27804042/esophageal-mucosal-integrity-improves-after-laparoscopic-antireflux-surgery-in-children-with-gastroesophageal-reflux-disease
#14
Femke A Mauritz, Nicolaas F Rinsma, Ernest L W van Heurn, Cornelius E J Sloots, Peter D Siersema, Roderick H J Houwen, David C van der Zee, Ad A M Masclee, José M Conchillo, Maud Y A Van Herwaarden-Lindeboom
BACKGROUND: Esophageal intraluminal baseline impedance reflects the conductivity of the esophageal mucosa and may be an instrument for in vivo evaluation of mucosal integrity in children with gastroesophageal reflux disease (GERD). Laparoscopic antireflux surgery (LARS) is a well-established treatment option for children with proton pump inhibitory (PPI) therapy resistant GERD. The effect of LARS in children on baseline impedance has not been studied in detail. The aim of this study was to evaluate the effect of LARS on baseline impedance in children with GERD...
November 1, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27769085/role-of-intraluminal-esophageal-impedance-baseline-in-the-diagnosis-of-esophagitis-in-children
#15
Miguel Couselo, Vicente Ibáñez, Javier Lluna, Juan José Vila
Introduction Low values of esophageal impedance baseline (EIB) have been related to esophagitis. The aim of this study was to evaluate the diagnostic performance of EIB for erosive esophagitis (ErE) and histological esophagitis (HiE) in children studied for gastroesophageal reflux. Material and Methods Children who underwent esophageal multichannel intraluminal impedance-pH monitoring (MII-pH) and upper-endoscopy with esophageal biopsies were studied retrospectively. EIB values were obtained by MII-pH. ErE was assessed by endoscopy following the Hetzel-Dent classification; HiE was defined by basal zone hyperplasia, papillary lengthening, or inflammatory infiltration...
February 2017: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27727523/the-importance-of-combined-24-hour-multichannel-intraluminal-impedance-ph-monitoring-in-the-evaluation-of-children-with-suspected-laryngopharyngeal-reflux
#16
I Pavić, I Babić, J Čepin Bogović, I Hojsak
OBJECTIVE: The aim of this study was to investigate the diagnostic usefulness of combined multichannel intraluminal impedance-pH (MII-pH) monitoring in children with suspected laryngopharyngeal reflux (LPR). DESIGN, SETTING AND PARTICIPANTS: A prospective study including children in whom, due to LPR suggestive symptoms, MII-pH monitoring was performed at tertiary medical centre from February 2012 to July 2015. INTERVENTIONS: All included children underwent same diagnostic protocol which included examination by single pulmonologist and ENT specialist and underwent 24-hour MII-pH monitoring...
October 11, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27682990/reflux-monitoring-in-children
#17
REVIEW
M M J Singendonk, M A Benninga, M P van Wijk
Recently, multichannel intraluminal impedance (MII) monitoring was added to the repertoire of tests to evaluate the (patho)physiology of gastroesophageal reflux (GER) in children. Its advantage above the sole monitoring of the esophageal pH lies in the ability of the detection of both acid and nonacid GER and to discern between liquid and gas GER. Currently, combined 24 h pH-MII monitoring is recommended for evaluation of gastro-esophageal reflux disease (GERD) and its relation to symptoms in infants and children, despite the lack of reference values in these age groups...
October 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27644732/functional-heartburn-overlaps-with-irritable-bowel-syndrome-more-often-than-gerd
#18
Nicola de Bortoli, Leonardo Frazzoni, Edoardo V Savarino, Marzio Frazzoni, Irene Martinucci, Aleksandra Jania, Salvatore Tolone, Michele Scagliarini, Massimo Bellini, Elisa Marabotto, Manuele Furnari, Giorgia Bodini, Salvatore Russo, Lorenzo Bertani, Veronica Natali, Lorenzo Fuccio, Vincenzo Savarino, Corrado Blandizzi, Santino Marchi
OBJECTIVES: We aimed to evaluate the prevalence of irritable bowel syndrome (IBS) in patients with typical reflux symptoms as distinguished into gastroesophageal reflux disease (GERD), hypersensitive esophagus (HE), and functional heartburn (FH) by means of endoscopy and multichannel intraluminal impedance (MII)-pH monitoring. The secondary aim was to detect pathophysiological and clinical differences between different sub-groups of patients with heartburn. METHODS: Patients underwent a structured interview based on questionnaires for GERD, IBS, anxiety, and depression...
December 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27630010/the-impact-of-the-speed-of-food-intake-on-gastroesophageal-reflux-events-in-obese-female-patients
#19
Serhat Bor, Askin Erdogan, Berna Bayrakci, Esra Yildirim, Rukiye Vardar
Obesity increases the risk of gastroesophageal reflux disease (GERD). The majority of the reflux attacks occur postprandially. The influence of the speed of food intake on gastroesophageal reflux events is unclear in obese patients. To determine the influence of the speed of food intake on intraesophageal reflux events in obese patients with and without GERD. A total of 26 obese female patients were recruited. The patients underwent esophageal manometry to evaluate the upper limit of the lower esophageal sphincter and subsequently placement of a Multichannel intraluminal impedance-pH (MII-pH) catheter...
September 15, 2016: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/27625129/-the-expression-and-significance-of-pepsin-in-laryngeal-carcinoma
#20
J J Tan, L Wang, Z F Huang, Y F Li, W D Tian, X Liu, F F Zeng, X P Li
OBJECTIVE: To evaluate the relationship between pepsin induced by laryngopharyngeal reflux and laryngeal carcinoma. METHODS: Patients with vocal cord leukoplakia(n=18) and laryngeal carcinoma(n=21) encountered in Nanfang Hospital between December 2012 and April 2014 were included and sixteen healthy volunteers were recruited as control. Laryngeal biopsy specimens were taken from the patients with laryngeal carcinoma, or vocal cord leukoplakia and control subjects for the immunohistochemical study of pepsin...
August 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
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