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JOURNAL ARTICLE
M T Yilmaz, S Kamer, F Agaoglu, K M Hayran, F Yildiz
AIMS: The International Lymphoma Radiation Oncology Group (ILROG) defined involved-site radiotherapy (ISRT) guidelines. These rules offer a certain variability that allows for autonomous decision-making in diverse clinical settings. However, this flexibility also gives rise to conflicts about the selection of treatment fields in the daily decision-making process. The aim of this study was to show the extent of interobserver variability when ILROG-ISRT recommendations were used in different clinical scenarios...
November 28, 2023: Clinical Oncology: a Journal of the Royal College of Radiologists
#22
REVIEW
Sara K Neches, Cassandra DeMartino, Rebecca Shay
Premedication such as analgesia, sedation, vagolytics, and paralytics may improve neonatal tracheal intubation success, reduce intubation-associated adverse events, and create optimal conditions for performing this high-risk and challenging procedure. Although rapid sequence induction including a paralytic agent has been adopted for intubations in pediatric and adult critical care, neonatal clinical practice varies. This review aims to summarize details of common classes of neonatal intubation premedication including indications for use, medication route, dosage, potential adverse effects in term and preterm infants, and reversal agents...
December 1, 2023: NeoReviews
#23
JOURNAL ARTICLE
Julie Goswami, Jacob Baxter, Brenda M Schiltz, Terri A Elsbernd, Grace M Arteaga, Denise B Klinkner
OBJECTIVES: The American College of Surgeons Trauma Quality Improvement Program (TQIP) and Committee on Trauma released a best practice guideline for palliative care in trauma patients in 2017. Utilization of pediatric palliative care services for pediatric trauma patients has not been studied. We sought to identify patients who received the consultation and develop criteria for patients who would benefit from these resources at our institution. METHODS: The institutional pediatric trauma registry was queried to identify all admissions age 0-17 years old to the pediatric intensive care unit (PICU) or trauma ICU (TICU) from 2014 to 2021...
2023: Trauma Surgery & Acute Care Open
#24
JOURNAL ARTICLE
Yahya H Khormi, Mohamed M Aly, Hossam K Hamda, Aly Abdelrahman Yousef, Adel Ibrahim Hanbashi, Mostafa M E Atteya
BACKGROUND: Traumatic retroclival hematomas (RCHs) are infrequent occurrences among the pediatric population. The existing body of research pertaining to these hematomas primarily consists of case reports or small case series, which do not provide adequate guidance for managing this condition. OBJECTIVE: This study aims to present a report on four cases of RCHs. Additionally, we aim to conduct a systematic review to consolidate the existing literature on pediatric RCHs...
November 27, 2023: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
#25
JOURNAL ARTICLE
Randall Chesnut, Nancy Temkin, James Pridgeon, Stephen Sulzbacher, Silvia Lujan, Walter Videtta, Luis Moya-Barquín, Kelley Chaddock, Robert H Bonow, Gustavo Petroni, Nahuel Guadagnoli, Peter Hendrickson, Grimaldo Ramírez Cortez, Nilton Yhuri Carreazo, Alcides Vargas Aymituma, Daniel Anchante, Patrick Caqui, Alberto Ramírez, Manuel Munaico Abanto, Manuel Ortiz Chicchon, José Cenzano Ramos, María Del Carmen Castro Darce, Roberto Sierra Morales, Pedro Brol Lopez, Willy Menendez, Sofía Posadas Gutierrez, Vicente Kevin, Andrea Mazariegos, Elie de Leon, Rodolfo Enrique Rodas Barrios, Sandra Rodríguez, Sandra Flores, Ovidio Alvarado, Luis José Guzman Flores, Melvin Moisa Martinez, Pablo Gonzalez
BACKGROUND AND OBJECTIVES: The efficacy of our current approach to incorporating intracranial pressure (ICP) data into pediatric severe traumatic brain injury (sTBI) management is incompletely understood, lacking data from multicenter, prospective, randomized studies. The National Institutes of Health-supported Benchmark Evidence from Latin America-Treatment of Raised Intracranial Pressure-Pediatrics trial will compare outcomes from pediatric sTBI of a management protocol based on ICP monitoring vs 1 based on imaging and clinical examination without monitoring...
November 13, 2023: Neurosurgery
#26
JOURNAL ARTICLE
Marwa Ramsie, Po-Yin Cheung, Tze-Fun Lee, Megan O'Reilly, Georg M Schmölzer
BACKGROUND: Current neonatal resuscitation guidelines recommend epinephrine for cardiac arrest. Vasopressin might be an alternative during asphyxial cardiac arrest. We aimed to compare vasopressin and epinephrine on incidence and time to return of spontaneous circulation (ROSC) in asphyxiated newborn piglets. DESIGN/METHODS: Newborn piglets (n = 8/group) were anesthetized, intubated, instrumented, and exposed to 30 min of normocapnic hypoxia, followed by asphyxia and asystolic cardiac arrest...
November 8, 2023: Pediatric Research
#27
JOURNAL ARTICLE
Peter Juviler, Jeffrey M Meyers, Elizabeth Levatino, Jessica Axford, Erin Barker, Lynnie Correll, Andrew S Decker, John Faria, Marjorie Gloff, Anthony Loria, Margo McKenna, Jan Schriefer, Timothy P Stevens, Sarah Verna, Sarah Wegman, Kori Wolcott, Derek Wakeman
BACKGROUND: Unplanned intubation following children's surgery is associated with increased postoperative mortality. In response to being a National Surgical Quality Improvement Program - Pediatric (NSQIP-P) high outlier for postoperative unplanned intubation, we aimed to reduce postoperative unplanned intubation events by 25% in one year. METHODS/INTERVENTION: A multidisciplinary team of stakeholders was assembled in 2018. Most unplanned intubation events occurred in the neonatal intensive care unit (NICU)...
September 22, 2023: Journal of Pediatric Surgery
#28
JOURNAL ARTICLE
Michael Westhoff, Peter Neumann, Jens Geiseler, Johannes Bickenbach, Michael Arzt, Martin Bachmann, Stephan Braune, Sandra Delis, Dominic Dellweg, Michael Dreher, Rolf Dubb, Hans Fuchs, Nina Hämäläinen, Hans Heppner, Stefan Kluge, Matthias Kochanek, Philipp M Lepper, F Joachim Meyer, Bernhard Neumann, Christian Putensen, Dorit Schimandl, Bernd Schönhofer, Dierk Schreiter, Stephan Walterspacher, Wolfram Windisch
The guideline update outlines the advantages as well as the limitations of NIV in the treatment of acute respiratory failure in daily clinical practice and in different indications.Non-invasive ventilation (NIV) has a high value in therapy of hypercapnic acute respiratory failure, as it significantly reduces the length of ICU stay and hospitalization as well as mortality.Patients with cardiopulmonary edema and acute respiratory failure should be treated with continuous positive airway pressure (CPAP) and oxygen in addition to necessary cardiological interventions...
October 13, 2023: Pneumologie
#29
JOURNAL ARTICLE
C Satragno, M Barboro, A Alparone, G Fiorella, M Turazzi, S Campora, S E Cena, A Coco, D Esposito, A Ferrero, A Ginulla, S Mastrogiovanni, F Piciche, C Scaffidi, C Tominai, F Cavagnetto, D Zefiro, F Giannelli, S Barra, L Belgioia
PURPOSE/OBJECTIVE(S): This study aims to develop an atlas-based method for segmentation of the scalp in pediatric patients that received brain radiotherapy. The study focuses on the development of a model that utilizes CT scans of pediatric medulloblastoma (MB) patients who underwent craniospinal-irradiation (CSI) and a boost in the posterior cranial fossa (PCF). MATERIALS/METHODS: A team of experts created the Alopecia_Hope (A_H) contouring protocol on the CT scan using the 2018 EPTN consensus-based atlas and by defining for the manual adjustments the anatomic bone landmarks to differentiate between the scalp and the facial and neck skin...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
#30
REVIEW
Ehsan Mohammad Hosseini, Saber Zafarshamspour, Mohammad Ghasemi-Rad, Goetz Benndorf, Alireza Rasekhi, Reza Rafieossadat
BACKGROUND: Traumatic intracranial aneurysms (TICAs) constitute a notable portion of pediatric intracranial aneurysms. Their unstable structure dictates a high incidence of rupture or mass effect from enlarging unruptured aneurysms, necessitating prompt diagnosis and treatment. TICAs often lack a true neck or are wide-necked, making them unsuitable for coil embolization and surgical clipping, and their fragile nature poses a risk of rupture during surgical and intrasaccular interventions...
September 26, 2023: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
#31
Alex S Aguirre, Kenny Rojas, Alcy R Torres
BACKGROUND: Pediatric casualties in war zones are a devastating consequence of armed conflicts, causing significant challenges for affected children, especially in the context of poor access to care. This study aimed to understand traumatic brain injuries (TBIs) in this high-risk population and to identify and provide information for the stakeholders, as well as to recognize severe long-term consequences and develop strategies to prevent them, thus minimizing their burden while aiding in the management of these cases...
2023: Frontiers in Neurology
#32
MULTICENTER STUDY
Syeda Kashfi Qadri, Jan Hau Lee, Yanan Zhu, Paula Caporal, Juan D Roa G, Sebastián González-Dambrauskas, Adriana Yock-Corrales, Qalab Abbas, Yasser Kazzaz, Luming Shi, Dianna Sri Dewi, Shu-Ling Chong
PURPOSE: Children with moderate traumatic brain injury (modTBI) (Glasgow Coma Scale (GCS) 9-13) may benefit from better stratification. We aimed to compare neurocritical care utilization and functional outcomes between children with high GCS modTBI (hmodTBI, GCS 11-13), low GCS modTBI (lmodTBI, GCS 9-10), and severe TBI (sTBI, GCS ≤ 8). We hypothesized that patients with lmodTBI have higher neurocritical care needs and worse outcomes than patients with hmodTBI and are similar to patients with sTBI...
November 2023: Acta Neurochirurgica
#33
JOURNAL ARTICLE
David J Harrison, Kevin P Daly, Kimberlee Gauvreau, Sonia F Epstein, Michelle L Walsh, Steve Colan, Christine Duncan, Leslie Lehmann, Ming Hui Chen
BACKGROUND: Patients who have undergone hematopoietic stem cell transplant (HSCT) during childhood carry a higher risk of diastolic heart failure (HF). The rate of progression of diastolic dysfunction in aging pediatric patients is unknown, and more difficult to assess in young patients secondary to changes in diastolic indices as they grow. OBJECTIVE: HSCT patients at our center were previously found to have decline in diastolic function indices 1 year after HSCT...
September 2, 2023: Transplantation and cellular therapy
#34
JOURNAL ARTICLE
Dominique Dupont, Danaë Larivière-Bastien, Jeffrey G Caron, Cindy Beaudoin, Jocelyn Gravel, Isabelle Gagnon, Brett Burstein, Myriam Beaudin, Sean C Rose, Keith O Yeates, Miriam H Beauchamp
OBJECTIVE: Little is known about the symptoms, signs, and management guidelines for children under the age of 6 years after they sustain a concussion. Caregivers of such young children may have unique concerns and encounter different challenges from those of school-age children given the distinctive developmental characteristics of the early childhood period. This study aimed to explore the experience of caregivers through semistructured interviews to inform clinical practice. METHODS: Fifty caregivers of children aged 6 months to 5...
August 14, 2023: Journal of Pediatric Psychology
#35
REVIEW
Jasmina Kovacevic, Michael Alexander Silva, Henry Chang, Mynor Josue Mendez Valdez, Ian Ramsay, Uche C Ezeh, Andres M Corona, Ahmed Abdelsalam, Robert M Starke
BACKGROUND: Intracranial dural arteriovenous fistulas (DAVFs) have been documented to occasionally spontaneously regress. However, the mechanism responsible for this occurrence remains speculative. METHODS: We present a case of a Borden II - Cognard IIa+b DAVF involving the superior sagittal sinus (SSS) with bilateral external carotid artery supply that regressed spontaneously. A systematic literature review was conducted to explore the current theories explaining the spontaneous regression of DAVFs according to Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines...
2023: Surgical Neurology International
#36
JOURNAL ARTICLE
Saad Alhumaid, Koblan M Al Mutared, Zainab Al Alawi, Zainah Sabr, Ola Alkhars, Muneera Alabdulqader, Nourah Al Dossary, Fatemah M ALShakhs, Rabab Abbas Majzoub, Yousef Hassan Alalawi, Khalid Al Noaim, Abdulrahman A Alnaim, Mohammed A Al Ghamdi, Abdulaziz A Alahmari, Sawsan Sami Albattat, Yasin S Almubarak, Essam Mohammed Al Abdulmohsen, Hanan Al Shaikh, Mortadah Essa Alobaidan, Hadi Hassan Almusallam, Fatimah Mohammed Alhassan, Mohammed Abdulhadi Alamer, Jawad Ali Al-Hajji, Duaa Ali Al-Hajji, Anwar Ahmed Alkadi, Abbas Al Mutair, Ali A Rabaan
BACKGROUND: Inborn errors of immunity (IEIs) are considered significant challenges for children with IEIs, their families, and their medical providers. Infections are the most common complication of IEIs and children can acquire coronavirus disease 2019 (COVID-19) even when protective measures are taken. OBJECTIVES: To estimate the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children with IEIs and analyse the demographic parameters, clinical characteristics and treatment outcomes in children with IEIs with COVID-19 illness...
August 9, 2023: Allergy, Asthma, and Clinical Immunology
#37
JOURNAL ARTICLE
Emma Larson, Brian Lim Park, Anita Thomas, Daisy Ciener, Julie Augenstein, Suzan Mazor, Rebekah Burns
INTRODUCTION: Jimson weed is a poisonous plant containing tropane alkaloids that can cause anticholinergic toxicity. Recognition of anticholinergic toxidrome is important for prevention and management of potentially life-threatening complications of severe toxicity, including dysrhythmia and seizure. METHODS: Designed for pediatric emergency medicine (PEM) fellows, this simulation featured a 15-year-old female presenting to the emergency department (ED) with agitation and hallucinations...
2023: MedEdPORTAL Publications
#38
REVIEW
Leslie C Appiah, Molly Moravek, Holly Hoefgen, Seth Rotz, Krista Childress, Jill Samis, Janie Benoit, Kenny Rodriguez-Wallberg, Antoinette Anazodo
Reproductive late effects after hematopoietic stem cell transplant can have a significant impact on cancer survivors' quality of life. Potential late effects include gonadal insufficiency, genital graft-versus-host disease, uterine injury, psychosexual dysfunction, and an increased risk of breast and cervical cancer in patients treated with total body irradiation. Despite guidelines, screening and treatment are not standardized among at-risk patients. Provider barriers include lack of knowledge of at-risk therapies and evidenced-based guidelines...
July 20, 2023: Pediatric Blood & Cancer
#39
REVIEW
Rüdiger Gerlach, Wolfram Kluwe
BACKGROUND: Traumatic brain injury (TBI) in children and adolescents is associated with significant morbidity and, in severe TBI, mortality. The aim of this article is to provide an overview of the spectrum of TBI, its pathophysiology, and current treatment recommendations for prehospital management of children and adolescents with TBI. MATERIALS AND METHODS: The current literature was reviewed for studies on the management of TBI in children and adolescents. RESULTS: In recent years, a large number of scientific studies have been published that have resulted in evidence-based guidelines for primary care of children with TBI...
July 14, 2023: Medizinische Klinik, Intensivmedizin und Notfallmedizin
#40
JOURNAL ARTICLE
Adrian D Zurca, Sebastián González-Dambrauskas, Jose Colleti, Pablo Vasquez-Hoyos, Arnaldo Prata-Barbosa, David Boothe, Bryan E Combs, Jan Hau Lee, Donna Franklin, Steven Pon, Todd Karsies, Steven L Shein
OBJECTIVES: Existing bronchiolitis guidelines do not reflect the needs of infants admitted to the PICU. This study aimed to identify PICU providers' reported practice variations and explore the need for critical bronchiolitis clinical guidelines. METHODS: Cross-sectional electronic survey available in English, Spanish, and Portuguese between November 2020 and March 2021, distributed via research networks from North and Latin America, Asia, and Australia/New Zealand...
July 10, 2023: Hospital Pediatrics
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