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Postpartum psychosis

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https://www.readbyqxmd.com/read/28373847/t-cell-deficits-and-overexpression-of-hepatocyte-growth-factor-in-anti-inflammatory-circulating-monocytes-of-middle-aged-patients-with-bipolar-disorder-characterized-by-a-high-prevalence-of-the-metabolic-syndrome
#1
Rogier J Vogels, Manja A Koenders, Elisabeth F C van Rossum, Annet T Spijker, Hemmo A Drexhage
BACKGROUND: We previously reported T cell deficits and pro-inflammatory gene activation in circulating monocytes of two cohorts of bipolar disorder (BD) patients, a cohort of postpartum psychosis patients and in bipolar offspring. Pro-inflammatory gene activation occurred in two clusters of mutually correlating genes, cluster 1 for inflammation-related cytokines/factors, cluster 2 for motility, chemotaxis, and metabolic factors. AIM: To verify these cellular immune abnormalities in yet another cohort [the bipolar stress study (BiSS) cohort] of relative old (52 years, median) BD patients and to relate immune abnormalities to hair cortisol levels, measured in this cohort and representing long-term systemic cortisol levels, and to the presence of the metabolic syndrome (MetS), which was prevalent in 29% of the BiSS patients...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28274337/catatonia-among-women-with-postpartum-psychosis-in-a-mother-baby-inpatient-psychiatry-unit
#2
Abhinav Nahar, Nithin Kondapuram, Geetha Desai, Prabha S Chandra
OBJECTIVE: The aims of the present study were to determine the prevalence of catatonia in women with postpartum psychosis, describe its socio demographic, clinical and obstetric correlates and identify predictors of treatment response. METHODS: Data was extracted from clinical charts of 200 women with postpartum psychosis admitted to an inpatient mother baby unit (MBU) in India over a 3year period. RESULTS: Of the 200 patients, 20% (n=40) had symptoms of catatonia...
March 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28262158/psychosis-as-a-late-manifestation-of-sheehan-s-syndrome
#3
Mukku Shiva Shanker Reddy, Abhinav Nahar, Harish Thippeswamy, Chaturvedi Santosh Kumar
Sheehan's syndrome occurs as a result of ischemic pituitary necrosis due to severe postpartum haemorrhage. It is one of the most common causes of hypopituitarism in underdeveloped or developing countries. Characteristic manifestations include failure to lactate or to resume menses, genital and axillary hair loss, asthenia and weakness, fine wrinkles around the eyes and lips, signs of premature aging, dry skin, hypopigmentation and other evidence of hypopituitarism. Uncommonly it can present with psychosis. There are only few case reports of psychoses in patients with Sheehan's syndrome...
February 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28154283/postpartum-anti-n-methyl-d-aspartate-receptor-encephalitis-a-case-report-and-literature-review
#4
REVIEW
Tadashi Doden, Yoshiki Sekijima, Junji Ikeda, Kazuki Ozawa, Nobuhiko Ohashi, Minori Kodaira, Akiyo Hineno, Naoko Tachibana, Shu-Ichi Ikeda
We describe a 24-year-old woman with anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis that developed 3 weeks after normal delivery. She was treated with methylprednisolone, intravenous immunoglobulin, and plasmapheresis, in addition to teratoma excision. However, her recovery was slow, and dysmnesia and mental juvenility persisted even two years after onset. To date, five patients with postpartum anti-NMDAR encephalitis have been reported. All of those patients showed psychotic symptoms and were suspected of having postpartum psychosis in the early period of the encephalitis...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28138996/a-qualitative-investigation-in-the-role-of-the-baby-in-recovery-from-postpartum-psychosis
#5
Charlene Plunkett, Sarah Peters, Angelika Wieck, Anja Wittkowski
Psychosis after childbirth is a rare but severe type of mental health difficulty experienced by perinatal women. Research has explored mothers' experiences of onset and recovery from psychosis after childbirth. This study explored the role of the baby in 12 mothers' experiences of recovery. A thematic analysis of the data identified three core themes that described the role of the baby in the mothers' recovery from psychosis after childbirth. Findings revealed that the baby was central to recovery, experienced by mothers as both helpful and unhelpful...
January 31, 2017: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/28112056/obstetrical-pregnancy-and-socio-economic-predictors-for-new-onset-severe-postpartum-psychiatric-disorders-in-primiparous-women
#6
S Meltzer-Brody, M L Maegbaek, S E Medland, W C Miller, P Sullivan, T Munk-Olsen
BACKGROUND: Childbirth is a potent trigger for the onset of psychiatric illness in women including postpartum depression (PPD) and postpartum psychosis (PP). Medical complications occurring during pregnancy and/or childbirth have been linked to postpartum psychiatric illness and sociodemographic factors. We evaluated if pregnancy and obstetrical predictors have similar effects on different types of postpartum psychiatric disorders. METHOD: A population-based cohort study using Danish registers was conducted in 392 458 primiparous women with a singleton delivery between 1995 and 2012 and no previous psychiatric history...
January 23, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/27987053/protection-against-hormone-mediated-mood-symptoms
#7
Leah C Susser, Alison D Hermann
We present the case of a woman with bipolar I disorder with severe premenstrual mood instability, confusion, and psychosis resembling the clinical features of postpartum psychosis when estrogen levels are expected to be low, and hypomania when estrogen levels are expected to be elevated. While depressive symptoms across the menstrual cycle have been extensively documented in the literature, there is little information regarding manic and hypomanic symptoms. In addition, we describe the successful treatment of her menstrual-cycle related symptoms...
December 16, 2016: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/27927846/risk-of-postpartum-psychosis-after-ivf-treatment-a-nationwide-case-control-study
#8
Josefin Vikström, Ann Josefsson, Mats Hammar, Marie Bladh, Gunilla Sydsjö
STUDY QUESTION: Is the risk of postpartum psychosis (PPP) increased in women who give birth after IVF treatment compared to after spontaneous conception? SUMMARY ANSWER: The risk of PPP is not higher in the group of women who give birth after IVF treatment compared with women who give birth after spontaneous conception. WHAT IS KNOWN ALREADY: Women who conceive using IVF treatment can experience higher levels of pregnancy-specific distress and are at increased risk of pre-eclampsia, an immune-related condition which in turn has been linked to PPP, as well as other pregnancy and delivery complications, which also serve as PPP risk factors...
January 2017: Human Reproduction
https://www.readbyqxmd.com/read/27917438/erratum-to-non-reproductive-triggers-of-postpartum-psychosis
#9
Ian Brockington
No abstract text is available yet for this article.
December 5, 2016: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/27832444/screening-for-and-treating-postpartum-depression-and-psychosis-a-cost-effectiveness-analysis
#10
Andra Wilkinson, Seri Anderson, Stephanie B Wheeler
Objectives Postpartum depression impacts 6.5-12.9% of U.S. women. Postpartum depression is associated with impaired bonding and development, marital discord, suicide, and infanticide. However, the current standard of care is to not screen women for postpartum depression. This study modeled the cost-effectiveness of physicians screening for and treating postpartum depression and psychosis in partnership with a psychiatrist. Methods This study follows a hypothetical cohort of 1000 pregnant women experiencing one live birth over a 2-year time horizon...
April 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/27778148/suicide-and-filicide-in-postpartum-psychosis
#11
Ian Brockington
This paper reviews the frequency of suicide and filicide in a literature of over 4000, and personal series of 321, childbearing psychoses. Suicide is rare during the acute episode, but the rate is high later in the mother's life and in first degree relatives. The filicide rate is high in depressive psychoses (4.5 %), but lower in episodes without overt depression (less than 1 %), and some of these appear to be accidental, without intent to kill.
February 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/27744500/some-unusual-forms-of-early-onset-postpartum-psychosis
#12
Ian Brockington
In addition to bipolar cycloid episodes, infective delirium and eclamptic psychosis, each of which has characteristic clinical features and course, brief episodes of delirium and stupor are also seen in the immediate aftermath of parturition. Several mothers have had similar episodes developing later in the first 10 days, and some have cyclical disorders with an unusual time base. Bipolar/cycloid disorders can start on day 1 or even earlier.
February 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/27736050/the-long-term-effects-of-maternal-postnatal-depression-on-a-child-s-intelligence-quotient-a-meta-analysis-of-prospective-cohort-studies-based-on-974-cases
#13
Guoyuan Sui, Bochen Pan, Guangcong Liu, Guangying Liu, Lie Wang
OBJECTIVE: Epidemiologists have explored the relationship between maternal postnatal depression (PND) and the intelligence quotient (IQ) of the resulting offspring, but the results remain inconclusive. This study aims to analyze the literature regarding the association between maternal PND and a child's IQ. DATA SOURCES: A search of articles in PubMed, Web of Science, and MEDLINE databases from inception to September 2015 was conducted and supplemented by a manual search of relevant reference lists...
November 2016: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/27734702/-psycho-immuno-endocrinology-of-the-thyroid-gland
#14
Ivan Šterzl, Karolína Absolonová, Petr Matucha
Historically endocrinologists and psychiatrists are aware that disturbances in thyroid disease in beginning or even in clinically intensified states of thyrotoxicosis or hypothyroidism exhibit pathological mental manifestations, masking or potentiating the underlying disease. Immune system disorders cause thyroid organ-specific autoimmune process. This autoimmune thyroid disease binds with a number of disorders in both endocrine or non-endocrine organs. This appears in vascular, neurological, skin, connective tissue, gastrointestinal tract and mental pathology...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27728876/a-pharmacological-mouse-model-suggests-a-novel-risk-pathway-for-postpartum-psychosis
#15
Trevor Humby, Ellen S Cross, Lauren Messer, Silvia Guerrero, William Davies
Postpartum psychosis (PP) is a severe psychiatric disorder affecting a small proportion of new mothers shortly after childbirth. The molecular pathophysiology underlying the disorder is currently poorly understood, and there are no amenable animal models for the condition; maternal deficiency for the enzyme steroid sulfatase has been proposed as a potential risk mechanism. Here we show that inhibition of steroid sulfatase with 667-COUMATE (10mg/kg p.o.) in new mouse mothers results in behavioural abnormalities that can be partially alleviated by the administration of the clinically-efficacious antipsychotic ziprasidone (0...
December 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27722949/non-reproductive-triggers-of-postpartum-psychosis
#16
Ian Brockington
Bipolar disorders, and other psychoses, are known to be triggered by a number of agents apart from the reproductive process. In some women, pregnant or recently delivered, psychosis may be due to these alternative triggers. There are substantial numbers of mothers suffering from childbearing psychoses, who have been prescribed bromocriptine or steroids, have had surgical operations or developed thyrotoxicosis. It is best to eliminate these episodes and cases from study samples of puerperal psychosis.
February 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/27714460/late-onset-postpartum-psychoses
#17
Ian Brockington
It has been known since the eighteenth century that postpartum psychoses can begin several weeks after childbirth, not during the first fortnight. There are almost 400 non-organic episodes in the literature, starting more than 3 weeks after the birth; some of them are recurrent. The distinction of this disorder from early onset puerperal psychosis is supported by the distribution of onsets (which shows a steep fall after 14-15 days), survey data and the association with later pregnancies, not the first. Marcé believed that these late onsets were related to the resumption of menstruation...
February 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/27631144/functional-recovery-after-postpartum-psychosis-a-prospective-longitudinal-study
#18
Karin M Burgerhout, Astrid M Kamperman, Sabine J Roza, Mijke P Lambregtse-Van den Berg, Kathelijne M Koorengevel, Witte J G Hoogendijk, Steven A Kushner, Veerle Bergink
OBJECTIVE: Postpartum psychosis is an acute and severe mood disorder. Although the prognosis is generally good, postpartum psychosis is a highly stressful life-event presumed to have a major impact on functioning and well-being beyond the acute stage of the illness. We studied functional recovery, including psychosocial functioning and the presence of psychological distress, in patients with a recent diagnosis of postpartum psychosis. METHODS: Seventy-eight patients with postpartum psychosis consecutively admitted for inpatient hospitalization between 2005 and 2011 were assessed 9 months postpartum...
January 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/27609245/postpartum-psychosis-madness-mania-and-melancholia-in-motherhood
#19
Veerle Bergink, Natalie Rasgon, Katherine L Wisner
OBJECTIVE: Psychosis or mania after childbirth is a psychiatric emergency with risk for suicide and infanticide. METHOD: The authors reviewed the epidemiologic and genetic research and physiological postpartum triggers (endocrine, immunological, circadian) of psychosis. They also summarized all systematic reviews and synthesized the sparse clinical studies to provide diagnostic recommendations, treatment options, and strategies for prevention. RESULTS: The incidence of first-lifetime onset postpartum psychosis/mania from population-based register studies of psychiatric admissions varies from 0...
December 1, 2016: American Journal of Psychiatry
https://www.readbyqxmd.com/read/27570512/suicide-during-perinatal-period-epidemiology-risk-factors-and-clinical-correlates
#20
REVIEW
Laura Orsolini, Alessandro Valchera, Roberta Vecchiotti, Carmine Tomasetti, Felice Iasevoli, Michele Fornaro, Domenico De Berardis, Giampaolo Perna, Maurizio Pompili, Cesario Bellantuono
Perinatal period may pose a great challenge for the clinical management and treatment of psychiatric disorders in women. In fact, several mental illnesses can arise during pregnancy and/or following childbirth. Suicide has been considered a relatively rare event during the perinatal period. However, in some mental disorders (i.e., postpartum depression, bipolar disorder, postpartum psychosis, etc.) have been reported a higher risk of suicidal ideation, suicide attempt, or suicide. Therefore, a complete screening of mothers' mental health should also take into account thoughts of suicide and thoughts about harming infants as well...
2016: Frontiers in Psychiatry
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