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https://www.readbyqxmd.com/read/29793189/effects-of-exposure-to-anti-vaping-public-service-announcements-among-current-smokers-and-dual-users-of-cigarettes-and-electronic-nicotine-delivery-systems
#1
Andy S L Tan, Vaughan W Rees, Justin Rodgers, Emeka Agudile, Natasha A Sokol, Kyeungyeun Yie, Ashley Sanders-Jackson
INTRODUCTION: Anti-vaping public service announcements (PSAs) are intended to discourage vaping or use of electronic nicotine delivery systems (ENDS). However, vaping portrayals in PSAs may have unintended effects if they increase smoking or vaping urges. This study examined benefits and unintended effects of anti-vaping PSAs with vapor portrayals on smoking and vaping-related outcomes. METHODS: Young adult smokers (N = 171) and dual users (N = 122) aged 21-30 years were randomly assigned to view: 1) anti-vaping PSAs with vapor; 2) anti-vaping PSAs without vapor; 3) physical activity PSAs; or 4) anti-smoking PSAs with smoking cues...
May 16, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29793150/exploring-the-victimization%C3%A2-early-substance-misuse-relationship-in-search-of-moderating-and-mediating-effects
#2
Glenn D Walters, Dorothy L Espelage
This study was designed to address two research questions. The first research question asked whether physical abuse victimization at the hands of parents/guardians, bullying victimization at the hands of peers, and the abuse x bullying interaction encouraged early involvement in substance misuse. The second research question inquired as to whether the victimization‒substance misuse relationship was mediated by variables proposed by various theories and research studies-specifically, cognitive impulsivity, negative affect, and low self-esteem...
May 21, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29793148/post-traumatic-stress-symptom-development-as-a-function-of-changing-witnessing-in-home-violence-and-changing-peer-post-traumatic-stress-symptom-development-as-a-function-of-changing-witnessing-in-home-violence-and-changing-peer-relationship-quality-evaluating
#3
Aura A Mishra, Sharon L Christ, Laura M Schwab-Reese, Nayantara Nair
In the present study, witnessing in-home violence and peer relationship quality are evaluated as to their relative impact on Post Traumatic Stress (PTS) symptoms among children aged 8 to 17 investigated by child protective services (CPS) for maltreatment exposure. The sample included 2151 children from the National Survey of Child and Adolescent Well-Being II (NSCAW II). Linear growth models were estimated to assess associations between changes in PTS symptoms, witnessing in-home violence, and peer relationship quality over time...
May 21, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29793139/the-use-of-low-intensity-pulsed-ultrasound-in-treating-delayed-union-of-fifth-metatarsal-fractures
#4
Kar Hao Teoh, Robert Whitham, Jenny F Wong, Kartik Hariharan
BACKGROUND: There are no studies looking at the success rate of low-intensity pulsed ultrasound (LIPUS) in fifth metatarsal fracture delayed unions to our knowledge. The aim of this study is to investigate the use of LIPUS treatment for delayed union of fifth metatarsal fractures. METHODS: A retrospective review of patients who were treated with LIPUS following a delayed union of fifth metatarsal fracture was conducted over a three-year period. RESULTS: There were thirty patients (9 males, 21 females) in this cohort...
January 31, 2018: Foot
https://www.readbyqxmd.com/read/29793102/joint-attention-in-down-syndrome-a-meta-analysis
#5
REVIEW
Laura J Hahn, Susan J Loveall, Madison T Savoy, Allie M Neumann, Toshikazu Ikuta
BACKGROUND: Some studies have indicated that joint attention may be a relative strength in Down syndrome (DS), but other studies have not. AIM: To conduct a meta-analysis of joint attention in DS to more conclusively determine if this is a relative strength or weakness when compared to children with typical development (TD), developmental disabilities (DD), and autism spectrum disorder (ASD). METHODS AND PROCEDURES: Journal articles published before September 13, 2016, were identified by using the search terms "Down syndrome" and "joint attention" or "coordinating attention"...
May 21, 2018: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29793085/socio-demographic-factors-associated-with-choosing-violent-methods-of-suicide-2011-2016-ilam-province
#6
Yousef Veisani, Fathola Mohamadian, Ali Delpisheh, Salman Khazaei
BACKGROUND: In new strategies towards of suicide prevention the best approach currently is based on specific method had specific risk factors. Therefore in this study we aimed to find out the association between socio-demographic factors and methods in completed suicide, 2011-2016, Ilam province. METHODS: A cross-sectional study, 2011-2016, was conducted. A total of 540 completed suicides were recruited to the study. Data were collected by systematic registration suicide data (SRSD) and Legal Medicine Organization (LMO)...
May 21, 2018: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29793068/prenatal-phthalate-exposure-birth-outcomes-and-dna-methylation-of-alu-and-line-1-repetitive-elements-a-pilot-study-in-china
#7
Li-Li Huang, Bin Zhou, Song-Hua Ai, Pan Yang, Ying-Jun Chen, Chong Liu, Yan-Ling Deng, Qing Lu, Xiao-Ping Miao, Wen-Qing Lu, Yi-Xin Wang, Qiang Zeng
BACKGROUND: Epigenetic mechanisms, such as altered DNA methylation, may participate in the relationship between prenatal phthalate exposure and adverse birth outcomes. OBJECTIVE: To explore the mediation effect of DNA methylation in the associations of phthalate exposure before delivery with birth outcomes in a Chinese cohort. METHODS: Eight phthalate metabolites in maternal urine before delivery and DNA methylation of Alu and long interspersed nucleotide elements (LINE-1) in cord blood were determined among 106 mother-infant pairs...
May 7, 2018: Chemosphere
https://www.readbyqxmd.com/read/29792994/lumbar-spinal-stenosis-comparison-of-surgical-practice-variation-and-clinical-outcome-in-three-national-spine-registries
#8
Greger Lønne, Peter Fritzell, Olle Hägg, Dennis Nordvall, Paul Gerdhem, Tobias Lagerbäck, Mikkel Andersen, Søren Eiskjaer, Martin Gehrchen, Wilco Jacobs, Miranda L van Hooff, Tore K Solberg
BACKGROUND: Decompression surgery for lumbar spinal stenosis (LSS) is the most common spinal procedure in the elderly. To avoid persisting low back pain, adding arthrodesis has been recommended, especially if there is a coexisting degenerative spondylolisthesis. However, this strategy remains controversial, resulting in practice-based variation. PURPOSE: To evaluate in a pragmatic study if surgical selection criteria and variation in use of arthrodesis in three Scandinavian countries can be linked to variation in treatment effectiveness...
May 21, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29792940/a-randomized-control-trial-to-determine-the-effectiveness-and-physiological-effects-of-spinal-manipulation-and-spinal-mobilization-compared-to-each-other-and-a-sham-condition-in-patients-with-chronic-low-back-pain-study-protocol-for-the-relief-study
#9
Brian C Clark, David W Russ, Masato Nakazawa, Christopher R France, Stevan Walkowski, Timothy D Law, Megan Applegate, Niladri Mahato, Samuel Lietkam, James Odenthal, Daniel Corcos, Simeon Hain, Betty Sindelar, Robert J Ploutz-Snyder, James S Thomas
BACKGROUND: Low back pain (LBP) is one of the most common reasons for seeking medical care. Manipulative therapies are a common treatment for LBP. Few studies have compared the effectiveness of different types of manipulative therapies. Moreover, the physiologic mechanisms underlying these treatments are not fully understood. Herein, we present the study protocol for The Researching the Effectiveness of Lumbar Interventions for Enhancing Function Study (The RELIEF Study). METHODS AND STUDY DESIGN: The RELIEF Study is a Phase II RCT with a nested mechanistic design...
May 21, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29792873/effect-of-alzheimer-s-disease-risk-and-protective-factors-on-cognitive-trajectories-in-subjective-memory-complainers
#10
Stefan J Teipel, Enrica Cavedo, Simone Lista, Marie-Odile Habert, Marie-Claude Potier, Michel J Grothe, Stephane Epelbaum, Luisa Sambati, Geoffroy Gagliardi, Nicola Toschi, Michael Greicius, Bruno Dubois, Harald Hampel
INTRODUCTION: Cognitive change in people at risk of Alzheimer's disease (AD) such as subjective memory complainers is highly variable across individuals. METHODS: We used latent class growth modeling to identify distinct classes of nonlinear trajectories of cognitive change over 2 years follow-up from 265 subjective memory complainers individuals (age 70 years and older) of the INSIGHT-preAD cohort. We determined the effect of cortical amyloid load, hippocampus and basal forebrain volumes, and education on the cognitive trajectory classes...
May 21, 2018: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/29792847/the-polymorphisms-of-atoh-7-et-1-and-ace-in-non-arteritic-anterior-ischemic-optic-neuropathy
#11
Ting Chen, Jin Ma, Guangliang Shan, Yong Zhong
Non-arteritic anterior ischemic optic neuropathy (NAION) is a common cause of acute optic neuropathy in the elderly. The role of the genetic polymorphisms of Atonal Homolog 7 (ATOH7), Endothelin-1 (ET-1) and Angiotensin Converting Enzyme (ACE) in NAION and the combined effects of the gene-gene and gene-medical comorbidities on NAION were not clear. We conducted a perspective, case-control study. 71 NAION patients and 142 age and sex-matched healthy controls were enrolled. Single nucleotide polymorphisms of ATOH7 (rs1900004), ET-1 (rs5370) and ACE (rs1799752) were identified by polymerase chain reaction (PCR) method and all PCR products were screened with Sanger sequencing...
May 21, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29792826/fast-evolving-human-specific-neural-enhancers-are-associated-with-aging-related-diseases
#12
Han Chen, Chunyan Li, Zhicheng Zhou, Han Liang
The antagonistic pleiotropy theory hypothesizes that evolutionary adaptations maximizing the fitness in early age increase disease burden after reproduction. This theory remains largely untested at the molecular level. Here, we analyzed enhancer evolution in primates to investigate the relationships between aging-related diseases and enhancers acquired after the human-chimpanzee divergence. We report a 5-fold increased evolutionary rate of enhancers that are activated in neural tissues, leading to fixation of ∼100 human-specific enhancers potentially under adaptation...
May 23, 2018: Cell Systems
https://www.readbyqxmd.com/read/29792756/uterine-or-paracervical-lidocaine-application-for-pain-control-during-intrauterine-contraceptive-device-insertion-a-meta-analysis-of-randomised-controlled-trials
#13
Faustino R Perez-Lopez, Samuel J Martinez-Dominguez, Gonzalo R Perez-Roncero, Adrian V Hernandez
OBJECTIVE: Systematic review and meta-analysis to assess the effects of uterine or paracervical lidocaine application on pain control during IUD insertion. METHODS: PubMed and five other electronic research databases were searched through 15 November 2017 for RCTs comparing lidocaine treatment vs. a control (placebo or no-intervention) to prevent pain during IUD insertion. Searched terms included 'IUD insertion', 'lidocaine' and 'randomised controlled trial'. RCTs evaluating lidocaine treatment before IUD insertion without restriction of language, age and IUD type...
May 24, 2018: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/29792749/engagement-with-a-text-messaging-intervention-improves-adherence-in-adolescents-with-type-1-diabetes-brief-report
#14
Shuodan Zhang, Emily Hamburger, Sachini Kahanda, Morgan Lyttle, Rodayne Williams, Sarah S Jaser
Adherence to diabetes management is a challenge for adolescents with type 1 diabetes (T1D). Positive psychology interventions have improved adherence to treatment recommendations in adults with chronic health conditions but have not been widely tested in pediatric populations. We hypothesized that higher engagement with a text-messaging intervention to promote positive affect would increase the effects on diabetes management among adolescents with T1D. Adolescents with T1D (n = 48) and their caregivers were randomized to either an attention control condition or a novel positive psychology intervention delivered through personalized automated text messaging...
May 2018: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29792708/nonalcoholic-fatty-liver-disease-and-diabetes-is-associated-with-decreased-cyp3a4-protein-expression-and-activity-in-human-liver
#15
Rohitash Jamwal, Suzanne M de la Monte, Ken Ogasawara, Sravani Adusumalli, Benjamin B Barlock, Fatemeh Akhlaghi
Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease in Western population. We investigated the effect of nonalcoholic fatty liver disease (NAFLD) and diabetes mellitus on CYP3A4 activity in human liver tissue from brain dead donors (N=74). Histopathologically graded livers were grouped into normal (n=24), nonalcoholic fatty liver (NAFL, n=26) and nonalcoholic steatohepatitis (NASH, n=24) categories. The rate of conversion of midazolam to its 1-hydroxy metabolite was used to assess in vitro CYP3A4 activity in human liver microsomes (HLM)...
May 24, 2018: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29792701/spatial-and-temporal-variability-in-emissions-of-fluorinated-gases-from-a-california-landfill
#16
Nazli Yesiller, James L Hanson, Alexander H Sohn, Jean Bogner, Donald R Blake
Emissions of twelve F-gases and methane were quantified using large-scale static chambers as a function of cover type (daily, intermediate, final) and seasonal variation (wet, dry) at a California landfill. The majority of the F-gas fluxes was positive and varied over 7 orders of magnitude across the cover types in a given season (wet: 10-8 to 10-1 g/m2-day; dry: 10-9 to 10-2 g/m2-day). The highest fluxes were from active filling areas with thin, coarse-grained daily covers, whereas the lowest fluxes were from the thick, fine-grained final cover...
May 24, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29792587/child-abuse-potential-in-mothers-with-early-life-maltreatment-borderline-personality-disorder-and-depression
#17
Katja Dittrich, Katja Boedeker, Dorothea Kluczniok, Charlotte Jaite, Catherine Hindi Attar, Daniel Fuehrer, Sabine C Herpertz, Romuald Brunner, Sibylle Maria Winter, Andreas Heinz, Stefan Roepke, Christine Heim, Felix Bermpohl
BACKGROUND: Early life maltreatment (ELM), borderline personality disorder (BPD) and major depressive disorder (MDD) have been shown to increase the potential of abuse. Emotion regulation is an identified mediator for the association of ELM and BPD with abuse potential. Until now, there has been no study to account for the co-occurrence of these risk factors in one analysis, although BPD and MDD are known as common sequelae of ELM. This is paired with a lack of studies investigating the effects of abuse potential on child well-being...
May 24, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29792581/victimization-and-violence-an-exploration-of-the-relationship-between-child-sexual-abuse-violence-and-delinquency
#18
Rebecca Shoaf Kozak, Melinda Gushwa, Tamara J Cadet
Child sexual abuse (CSA) continues to be a major public health issue with significant short- and long-term consequences. However, little contemporary research has examined the relationship between CSA and delinquent and violent behavior in adolescence. Children who have been sexually abused experience a unique form of victimization compared to children who have endured other forms of maltreatment, as CSA can result in feelings of shame, powerlessness and boundary violations. The purpose of this study was to examine the effect of CSA on delinquent and violent behavior in adolescence...
May 24, 2018: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/29792574/evaluation-of-a-mobile-application-for-pelvic-floor-exercises
#19
Michelle N Han, Tamara Grisales, Aparna Sridhar
BACKGROUND: Pelvic floor exercises are effective in improving muscle strength and urinary incontinence symptoms. Increasingly popular mobile applications can be effective in teaching patients these exercises. INTRODUCTION: A mobile application, Bwom© , aims to educate women about pelvic floor exercises with individually tailored plans relevant to the user's risk factors. The objective of this study is to assess the understandability and actionability of Bwom. MATERIALS AND METHODS: This is a cross-sectional survey of patients and providers at an academic medical center...
May 24, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29792567/effects-of-age-and-body-mass-index-on-breast-characteristics-a-cluster-analysis
#20
Celeste E Coltman, Julie R Steele, Deirdre E McGhee
Limited research has quantified variation in the characteristics of the breasts among women and determined how these breast characteristics are influenced by age and body mass. The aim of this study was to classify the breasts of women in the community into different categories based on comprehensive and objective measurements of the characteristics of their breasts and torsos, and to determine the effect of age and body mass index (BMI) on the prevalence of these breast categories. Four breast characteristic clusters were identified (X-Large, Very-ptotic & Splayed; Large, Ptotic & Splayed; Medium & Mildly-ptotic; and Small & Non-ptotic), with age and BMI shown to significantly affect the breast characteristic clusters...
May 24, 2018: Ergonomics
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