keyword
MENU ▼
Read by QxMD icon Read
search

postural instability aging

keyword
https://www.readbyqxmd.com/read/29776864/putaminal-dopamine-depletion-in-de-novo-parkinson-s-disease-predicts-future-development-of-wearing-off
#1
Su Jin Chung, Yoonju Lee, Jungsu S Oh, Jae Seung Kim, Phil Hyu Lee, Young H Sohn
INTRODUCTION: The present study aimed to investigate whether the level of presynaptic dopamine neuronal loss predicts future development of wearing-off in de novo Parkinson's disease. METHODS: This retrospective cohort study included a total of 342 non-demented patients with de novo Parkinson's disease who underwent dopamine transporter positron emission tomography scans at their initial evaluation and received dopaminergic medications for 24 months or longer. Onset of wearing-off was determined based on patients' medical records at their outpatient clinic visits every 3-6 months...
May 10, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29770907/sit-still-and-pay-attention-using-the-wii-balance-board-to-detect-lapses-in-concentration-in-children-during-psychophysical-testing
#2
Pete R Jones
During psychophysical testing, a loss of concentration can cause observers to answer incorrectly, even when the stimulus is clearly perceptible. Such lapses limit the accuracy and speed of many psychophysical measurements. This study evaluates an automated technique for detecting lapses based on body movement (postural instability). Thirty-five children (8-11 years of age) and 34 adults performed a typical psychophysical task (orientation discrimination) while seated on a Wii Fit Balance Board: a gaming device that measures center of pressure (CoP)...
May 16, 2018: Behavior Research Methods
https://www.readbyqxmd.com/read/29729353/influence-of-foot-position-and-vision-on-dynamic-postural-strategies-during-the-grand-pli%C3%A3-ballet-movement-squatting-in-young-and-adult-ballet-dancers
#3
Anne-Violette Bruyneel, Marc Bertrand, Serge Mesure
PURPOSE: To analyse dynamic postural strategies during the "grand plié" in two different foot positions (parallel or turned out), with and without vision, and as a function of age in ballet dancers. METHOD: Twenty young dancers (YD) aged from 8 to 16 years, and 20 adult dancers (AD) aged from 17 to 30 years were recruited. Center of pressure (CoP) and ground reaction forces (GRF) were recorded (500 Hz) during the grand plié (lowering, squatting and rising)...
May 2, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29713303/association-between-peripheral-inflammation-and-datscan-data-of-the-striatal-nuclei-in-different-motor-subtypes-of-parkinson-disease
#4
Hossein Sanjari Moghaddam, Farzaneh Ghazi Sherbaf, Mahtab Mojtahed Zadeh, Amir Ashraf-Ganjouei, Mohammad Hadi Aarabi
The interplay between peripheral and central inflammation has a significant role in dopaminergic neural death in nigrostriatal pathway, although no direct assessment of inflammation has been performed in relation to dopaminergic neuronal loss in striatal nuclei. In this study, the correlation of neutrophil to lymphocyte ratio (NLR) as a marker of peripheral inflammation to striatal binding ratios (SBRs) of DAT SPECT images in bilateral caudate and putamen nuclei was calculated in 388 drug-naïve early PD patients [288 tremor dominant (TD), 73 postural instability and gait difficulty (PIGD), and 27 indeterminate] and 148 controls...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29703644/comparison-of-two-motor-subtype-classifications-in-de-novo-parkinson-s-disease
#5
Seong-Min Choi, Byeong C Kim, Bang-Hoon Cho, Kyung Wook Kang, Kang-Ho Choi, Joon-Tae Kim, Seung-Han Lee, Man-Seok Park, Myeong-Kyu Kim, Ki-Hyun Cho
BACKGROUND: Clinical subtypes of Parkinson's disease (PD) have been empirically defined based on the prominent motor symptoms. The aim of this study was to compare the prevalence of non-motor symptoms across PD motor subtypes in patients with PD. METHODS: A total of 192 patients with de novo PD were included. The patients were classified into the tremor-dominant/mixed/akinetic-rigid (TD/mixed/AR) and tremor-dominant/mixed/postural instability and gait disturbance (TD/mixed/PIGD) subtypes, according to previous reports...
April 18, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29701258/evaluation-of-smartphone-based-testing-to-generate-exploratory-outcome-measures-in-a-phase-1-parkinson-s-disease-clinical-trial
#6
Florian Lipsmeier, Kirsten I Taylor, Timothy Kilchenmann, Detlef Wolf, Alf Scotland, Jens Schjodt-Eriksen, Wei-Yi Cheng, Ignacio Fernandez-Garcia, Juliane Siebourg-Polster, Liping Jin, Jay Soto, Lynne Verselis, Frank Boess, Martin Koller, Michael Grundman, Andreas U Monsch, Ronald B Postuma, Anirvan Ghosh, Thomas Kremer, Christian Czech, Christian Gossens, Michael Lindemann
BACKGROUND: Ubiquitous digital technologies such as smartphone sensors promise to fundamentally change biomedical research and treatment monitoring in neurological diseases such as PD, creating a new domain of digital biomarkers. OBJECTIVES: The present study assessed the feasibility, reliability, and validity of smartphone-based digital biomarkers of PD in a clinical trial setting. METHODS: During a 6-month, phase 1b clinical trial with 44 Parkinson participants, and an independent, 45-day study in 35 age-matched healthy controls, participants completed six daily motor active tests (sustained phonation, rest tremor, postural tremor, finger-tapping, balance, and gait), then carried the smartphone during the day (passive monitoring), enabling assessment of, for example, time spent walking and sit-to-stand transitions by gyroscopic and accelerometer data...
April 27, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29614464/identifying-balance-impairments-in-people-with-parkinson-s-disease-using-video-and-wearable-sensors
#7
Emma Stack, Veena Agarwal, Rachel King, Malcolm Burnett, Fatemeh Tahavori, Balazs Janko, William Harwin, Ann Ashburn, Dorit Kunkel
BACKGROUND: Falls and near falls are common among people with Parkinson's (PwP). To date, most wearable sensor research focussed on fall detection, few studies explored if wearable sensors can detect instability. RESEARCH QUESTION: Can instability (caution or near-falls) be detected using wearable sensors in comparison to video analysis? METHODS: Twenty-four people (aged 60-86) with and without Parkinson's were recruited from community groups...
March 28, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29610105/cortical-thinning-and-cognitive-impairment-in-parkinson-s-disease-without-dementia
#8
Lijun Zhang, Ming Wang, Nicholas W Sterling, Eun-Young Lee, Paul J Eslinger, Daymond Wagner, Guangwei Du, Mechelle M Lewis, Young Truong, F DuBois Bowman, Xuemei Huang
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized clinically by motor dysfunction (bradykinesia, rigidity, tremor, and postural instability), and pathologically by the loss of dopaminergic neurons in the substantia nigra of the basal ganglia. Growing literature supports that cognitive deficits may also be present in PD, even in non-demented patients. Gray matter (GM) atrophy has been reported in PD and may be related to cognitive decline. This study investigated cortical thickness in non-demented PD subjects and elucidated its relationship to cognitive impairment using high-resolution T1-weighted brain MRI and comprehensive cognitive function scores from 71 non-demented PD and 48 control subjects matched for age, gender, and education...
March 2018: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/29588088/the-etiologic-relation-between-disequilibrium-and-orthostatic-intolerance-in-patients-with-myalgic-encephalomyelitis-chronic-fatigue-syndrome
#9
Kunihisa Miwa, Yukichi Inoue
BACKGROUND: Orthostatic intolerance (OI) causes a marked reduction in the activities of daily living in patients with myalgic encephalomyelitis (ME) or chronic fatigue syndrome. Most symptoms of OI are thought to be related to cerebral hypo-perfusion and sympathetic activation. Because postural stability is an essential element of orthostatic tolerance, disequilibrium may be involved in the etiology of OI. METHODS AND RESULTS: The study comprised 44 patients with ME (men, 11 and women, 33; mean age, 37±9 years), who underwent neurological examinations and 10-min standing and sitting tests...
March 24, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29572571/exploring-the-relationship-between-motor-impairment-vascular-burden-and-cognition-in-parkinson-s-disease
#10
Tanja Stojkovic, Elka Stefanova, Ivan Soldatovic, Vladana Markovic, Iva Stankovic, Igor Petrovic, Federica Agosta, Sebastiano Galantucci, Massimo Filippi, Vladimir Kostic
OBJECTIVE: To determine frequency and type of cognitive disorders in cross-sectional analysis of a Parkinson's disease (PD) cohort, and explore its relations to motor symptoms, modifiable vascular risk factors and white matter lesions (WML) volume. METHODS: In a group of 133 PD patients, mild cognitive impairment (PD-MCI) and dementia (PDD) were diagnosed according to Movement Disorders Society Task Force criteria (level 2 for PD-MCI). Detailed motor measurements were applied, including rigidity, axial, bradykinesia, tremor and postural instability gait disorders (PIGD) scores...
March 23, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29547480/effect-of-gaze-stability-exercises-on-chronic-motion-sensitivity-a-randomized-controlled-trial
#11
Shilpa B Gaikwad, Eric G Johnson, Todd C Nelson, Oluwaseun I Ambode, Abdulaziz A Albalwi, Ahmad A Alharbi, Noha S Daher
BACKGROUND AND PURPOSE: Motion sensitivity is a common condition among the general population and may be accompanied by postural instability and anxiety. Preliminary studies suggest that minimal dosage of gaze stability exercises improves postural stability in young adults with chronic motion sensitivity. The aim of this study was to investigate the effect of progressive gaze stability exercises on postural stability, motion sensitivity, and anxiety in healthy young adults with chronic motion sensitivity...
April 2018: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/29471310/age-related-reduction-of-trunk-muscle-torque-and-prevalence-of-trunk-sarcopenia-in-community-dwelling-elderly-validity-of-a-portable-trunk-muscle-torque-measurement-instrument-and-its-application-to-a-large-sample-cohort-study
#12
Eiji Sasaki, Shizuka Sasaki, Daisuke Chiba, Yuji Yamamoto, Atsushi Nawata, Eiichi Tsuda, Shigeyuki Nakaji, Yasuyuki Ishibashi
Trunk muscle weakness and imbalance are risk factors for postural instability, low back pain, and poor postoperative outcomes. The association between trunk muscle strength and aging is poorly understood, and establishing normal reference values is difficult. We aimed to establish the validity of a novel portable trunk muscle torque measurement instrument (PTMI). We then estimated reference data for healthy young adults and elucidated age-related weakness in trunk muscle strength. Twenty-four university students were enrolled to validate values for PTMI, and 816 volunteers from the general population who were recruited to the Iwaki Health Promotion Project were included to estimate reference data for trunk muscle strength...
2018: PloS One
https://www.readbyqxmd.com/read/29462775/gait-analysis-in-patients-with-chronic-obstructive-pulmonary-disease-a-systematic-review
#13
REVIEW
Matteo Zago, Chiarella Sforza, Daniela Rita Bonardi, Enrico Eugenio Guffanti, Manuela Galli
BACKGROUND: Gait instability is a major fall-risk factor in patients with chronic obstructive pulmonary disease (COPD). Clinical gait analysis is a reliable tool to predict fall onsets. However, controversy still exists on gait impairments associated with COPD. RESEARCH QUESTION: Thus, the aims of this review were to evaluate the current understanding of spatiotemporal, kinematic and kinetic gait features in patients with COPD. METHODS: In line with PRISMA guidelines, a systematic literature search was performed throughout Web of Science, PubMed Medline, Scopus, PEDro and Scielo databases...
March 2018: Gait & Posture
https://www.readbyqxmd.com/read/29378790/features-of-gba-associated-parkinson-s-disease-at-presentation-in-the-uk-tracking-parkinson-s-study
#14
Naveed Malek, Rimona S Weil, Catherine Bresner, Michael A Lawton, Katherine A Grosset, Manuela Tan, Nin Bajaj, Roger A Barker, David J Burn, Thomas Foltynie, John Hardy, Nicholas W Wood, Yoav Ben-Shlomo, Nigel W Williams, Donald G Grosset, Huw R Morris
OBJECTIVES: To examine the influence of the glucocerebrosidase ( GBA ) mutation carrier state on age at onset of Parkinson's disease (PD), the motor phenotype and cognitive function at baseline assessment in a large cohort of UK patients. We also analysed the prevalence of mood and behavioural problems that may confound the assessment of cognitive function. METHODS: We prospectively recruited patients with PD in the Tracking Parkinson's study. We fully sequenced the GBA gene in all recently diagnosed patients (≤3...
January 29, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29370980/body-balance-at-static-posturography-in-vestibular-migraine
#15
Leslie Palma Gorski, Adriana Marques da Silva, Flávia Salvaterra Cusin, Suelen Cesaroni, Mauricio Malavasi Ganança, Heloisa Helena Caovilla
INTRODUCTION: Migraine is one of the most frequent and incapacitating headaches, with a high degree of impairment in quality of life. Its association with vestibular symptoms is common, including imbalance and postural instability. OBJECTIVE: To evaluate the body balance of patients with vestibular migraine through a static posturography test. METHODS: An experimental group of 31 patients with a medical diagnosis of vestibular migraine in the intercritical period of the disease, and a control group of 31 healthy individuals, matched for age and gender, were submitted to the eight sensory conditions of the Tetrax Interactive Balance System...
December 27, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29354156/lower-limbs-heterometry-correction-in-patients-with-osteoporosis-and-increased-risk-of-falls
#16
Elisa Pratelli, Angelo Alito, Claudio Zanella, Laura Busi, Giuseppe Mangone, Matteo Scarselli, Pietro Pasquetti
Osteoporotic fractures are associated with a significant increase in morbidity, mortality and medical costs. There is also a strong link between fractures and increased mortality. Among effective measures for the prevention of falls, instability treatment surely plays a crucial role. Several factors contribute to instability, many of which are ageing-related: visual spatial deficit, strength reduction, weight imbalance with COP lateralization sometimes favoured by LLD (leg length discrepancy). It seems useful to detect an heterometry which could be corrected, if present...
September 2017: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/29353740/gait-in-patients-with-adolescent-idiopathic-scoliosis-effect-of-surgery-at-10-years-of-follow-up
#17
Philippe Mahaudens, France Dalemans, Xavier Banse, Maryline Mousny, Olivier Cartiaux, Christine Detrembleur
PURPOSE: To assess radiological and gait biomechanical changes before, at one and 10 years after surgery in AIS patients. METHODS: This clinical prospective study included fifteen adult women (mean[SD] age: 26 [1] years) diagnosed with thoraco-lumbar/lumbar AIS and operated 10 years ago. Clinical, radiological and gait variables, including kinematics, electromyography (EMG), mechanics and energetics were compared between presurgery (S0), 1 year (S1) and 10 years (S2) postsurgery period using a one way repeated measure ANOVA...
March 2018: Gait & Posture
https://www.readbyqxmd.com/read/29288047/sway-regularity-and-sway-activity-in-older-adults-upright-stance-are-differentially-affected-by-dual-task
#18
Margarita Drozdova-Statkevičienė, Vida Janina Česnaitienė, Kazimieras Pukėnas, Oron Levin, Nerijus Masiulis
Age-related changes in postural control are attributed to visual, vestibular and proprioceptive dysfunctions, muscle weakness, and reduced availability of neural resources required for efficient balance control. Concurrent performance of complex cognitive tasks while standing or walking is expected to increase balance instability due to under-recruitment of brain resources and insufficient allocation of attention to the postural task. Both balance instability and attentional control of movements can, nonetheless, be determined from the center of pressure (CoP) measurements by examining the effects of dual-task on the amount of sway activity (as measured by CoP velocity - Vcop) and the statistical regularity of the CoP trajectory (the wavelet entropy of the signal - WEcop)...
February 14, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29205509/cerebrospinal-fluid-plasma-and-saliva-in-the-biofind-study-relationships-among-biomarkers-and-parkinson-s-disease-features
#19
Jennifer G Goldman, Howard Andrews, Amy Amara, Anna Naito, Roy N Alcalay, Leslie M Shaw, Peggy Taylor, Tao Xie, Paul Tuite, Claire Henchcliffe, Penelope Hogarth, Samuel Frank, Marie-Helene Saint-Hilaire, Mark Frasier, Vanessa Arnedo, Alyssa N Reimer, Margaret Sutherland, Christine Swanson-Fischer, Katrina Gwinn, Un Jung Kang
OBJECTIVE: Examine relationships among neurodegenerative biomarkers and PD motor and nonmotor symptoms. BACKGROUND: CSF alpha-synuclein is decreased in PD versus healthy controls, but whether plasma and saliva alpha-synuclein differentiate these groups is controversial. Correlations of alpha-synuclein among biofluids (CSF, plasma, saliva) or biomarkers (eg, beta-amyloid, tau [total, phosphorylated]) are not fully understood. The relationships of these biomarkers with PD clinical features remain unclear...
February 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29175640/an-exploratory-study-examining-factors-underpinning-postural-instability-in-older-adults-with-idiopathic-neck-pain
#20
June Quek, Julia Treleaven, Ross A Clark, Sandra G Brauer
There is limited understanding of potential mechanisms underpinning postural control deficits in people with neck pain. This study examined several characteristics that might explain impaired postural stability in a group of older adults with neck pain, and compared the results in this cohort with that of asymptomatic controls. In this cross-sectional study we compared physical activity, lower limb motor and sensory function, vestibular and visual function, falls efficacy and dizziness handicap in 84 older adults with (n=35, age 69...
February 2018: Gait & Posture
keyword
keyword
96394
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"