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postural instability aging

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https://www.readbyqxmd.com/read/28441826/-a-childhood-onset-rapid-onset-dystonia-parkinsonism-family-with-atp1a3-gene-mutation-and-literatures-review
#1
C L Zhang, F Yin, F He, N Gai, Z Q Shi, J Peng
Objective: To explore clinical characteristics, treatment, and prognosis of a family with childhood-onset rapid-onset dystonia parkinsonism (RDP) caused by ATP1A3 gene mutation and review literatures. Method: The clinical data of a RDP child, his brother and mother had been analyzed retrospectively. This family was admitted to Xiangya Hospital in January 2016. DNA samples were analyzed by the next-generation sequencing and confirmed by Sanger sequencing. Related literature from PubMed, Online Mendelian Inheritance in Man (OMIM), CNKI and Wanfang databases to date (up to October 2016) with"Rapid-onset dystonia-parkinsonism"RDP"DYT12" as key words was reviewed...
April 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28437758/balance-impairment-in-kidney-transplant-recipients-without-concurrent-peripheral-neuropathy
#2
T Zanotto, S Gobbo, V Bullo, B Vendramin, F Duregon, L Cugusi, A Di Blasio, L Furian, C Silvestre, D Neunhaeuserer, M Zaccaria, M Bergamin, A Ermolao
Kidney transplant recipients (KTRs) present with compromised functional capacity, low levels of physical activity, muscle atrophy, and peripheral nerve dysfunction that may result in high postural instability. This study aimed to compare the static balance control of 19 KTRs with 19 healthy adults (HA). All participants completed the Romberg test on a stabilometric platform with eyes open (EO), eyes closed (EC) and during a dual task (DT) condition. Centre of pressure (COP) measures (COP velocity (COPv) and sway area (SA)), as well as position-based outcomes such as anterior-posterior (AP) and medio-lateral (ML) ranges of COP displacements were recorded...
April 15, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28408876/effects-of-age-related-macular-degeneration-on-postural-sway
#3
Hortense Chatard, Laure Tepenier, Olivier Jankowski, Antoine Aussems, Alain Allieta, Talal Beydoun, Sawsen Salah, Maria P Bucci
Purpose: To compare the impact of unilateral vs. bilateral age-related macular degeneration (AMD) on postural sway, and the influence of different visual conditions. The hypothesis of our study was that the impact of AMD will be different between unilateral and bilateral AMD subjects compared to age-matched healthy elderly. Methods: Postural stability was measured with a platform (TechnoConcept®) in 10 elderly unilateral AMD subjects (mean age: 71.1 ± 4.6 years), 10 elderly bilateral AMD subjects (mean age: 70...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28395983/effects-of-holding-an-external-load-on-the-standing-balance-of-older-and-younger-adults-with-and-without-chronic-low-back-pain
#4
Leonardo Shigaki, Edgar Ramos Vieira, André Wilson de Oliveira Gil, Cynthia Gobbi Alves Araújo, Mariana Zingari Carmargo, Leandro Amaral Sturion, Marcio Roǵerio de Oliveira, Rubens A da Silva
OBJECTIVE: The purpose of this study was to assess the effect of holding an external load on the standing balance of younger and older adults with and without chronic low back pain (CLBP). METHODS: Twenty participants with and 20 without CLBP participated in the study. Each group contained 10 younger (50% men) and 10 older adults (50% men). Participants were instructed to look straight ahead while standing on a force platform during two 120-second trials with and without holding an external load (10% of body mass)...
April 8, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28385058/postural-sway-in-individuals-with-type-2-diabetes-and-concurrent-benign-paroxysmal-positional-vertigo
#5
Linda D'Silva, Patricia M Kluding, Susan L Whitney, Hongying Dai, Marcio Santos
BACKGROUND AND PURPOSE: Diabetes has been shown to affect the peripheral vestibular end organs and is associated with an increase in the frequency of benign paroxysmal positional vertigo (BPPV). People with diabetes have higher postural sway; however, the impact of symptomatic BPPV on postural sway in individuals with diabetes is unclear. The purpose of this cross-sectional study was to examine postural sway in people with type 2 diabetes who have symptomatic, untreated BPPV (BPPVDM)...
April 6, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28362143/stance-foot-alignment-and-hand-positioning-alter-star-excursion-balance-test-scores-in-those-with-chronic-ankle-instability-what-are-we-really-assessing
#6
Mutlu Cuğ
OBJECTIVE: The literature has consistently shown that the Star Excursion Balance Test (SEBT) is a reliable and valid tool to anticipate the risk of lower extremity injury, assess dynamic postural control differences among groups, and assess the effectiveness of balance training programs in both healthy individuals and people with lower extremity injuries. However, there is no standard administration technique for the SEBT in research, clinical practice, or performance settings. Therefore, the purpose of this investigation was to compare six different combinations (3 different foot alignments × 2 hand positions) on the SEBT performance in those with chronic ankle instability (CAI)...
March 31, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28356627/examination-of-center-of-pressure-displacement-and-muscle-activity-of-the-hip-girdle-muscles-on-lateral-movement-in-the-sitting-position-focusing-on-kinematic-features-before-and-after-the-start-of-exercise
#7
Kouji Ikeda, Kenji Suehiro, Akito Kizu, Hideki Kunieda, Hirokazu Takasaki, Toshiaki Suzuki
[Purpose] This study aimed to evaluate the kinematic characteristics at the start of lateral movement in the sitting position, for application in physical therapy. [Subjects and Methods] Eleven healthy male subjects (mean age, 24.8 ± 3.7 years) were included in the study after they provided informed consent. The electromyographic activities of the tensor fascia lata, gluteus medius, and rectus femoris, and the center of pressure (COP) displacement during lateral reach in the sitting position were measured...
March 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28326295/role-of-the-cytokine-like-hormone-leptin-in-muscle-bone-crosstalk-with-aging
#8
REVIEW
Mark W Hamrick
The cytokine-like hormone leptin is a classic adipokine that is secreted by adipocytes, increases with weight gain, and decreases with weight loss. Additional studies have, however, shown that leptin is also produced by skeletal muscle, and leptin receptors are abundant in both skeletal muscle and bone-derived mesenchymal (stromal) stem cells. These findings suggest that leptin may play an important role in muscle-bone crosstalk. Leptin treatment in vitro increases the expression of myogenic genes in primary myoblasts, and leptin treatment in vivo increases the expression of microRNAs involved in myogenesis...
February 2017: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/28295912/training-with-a-balance-exercise-assist-robot-is-more-effective-than-conventional-training-for-frail-older-adults
#9
Kenichi Ozaki, Izumi Kondo, Satoshi Hirano, Hitoshi Kagaya, Eiichi Saitoh, Aiko Osawa, Yoichi Fujinori
AIM: To examine the efficacy of postural strategy training using a balance exercise assist robot (BEAR) as compared with conventional balance training for frail older adults. METHODS: The present study was designed as a cross-over trial without a washout term. A total of 27 community-dwelling frail or prefrail elderly residents (7 men, 20 women; age range 65-85 years) were selected from a volunteer sample. Two exercises were prepared for interventions: robotic exercise moving the center of gravity by the balance exercise assist robot system; and conventional balance training combining muscle-strengthening exercise, postural strategy training and applied motion exercise...
March 10, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28279773/deep-brain-stimulation-of-pedunculopontine-nucleus-for-postural-instability-and-gait-disorder-after-parkinson-s-disease-a-meta-analysis-of-individual-patient-data
#10
Jia-Wei Wang, Yu-Qing Zhang, Xiao-Hua Zhang, Yun-Peng Wang, Ji-Ping Li, Yong-Jie Li
BACKGROUND: Postural instability and gait disorder(PIGD) in Parkinson's disease (PD) have been a great challenge in the clinical practice since PIGD is closely linked to major morbidity and mortality in PD. Pedunculopontine nucleus (PPN) has been considered as a potential promising target for deep brain stimulation (DBS) in the treatment of PIGD. Thus, this meta-analysis of individual patient data (IPD) was performed to assess the effects of PPN DBS on PIGD in PD patients and explore the factors predicting good outcome...
March 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28268273/postural-flexibility-during-quiet-standing-in-healthy-elderly-and-patients-with-parkinson-s-disease
#11
Kazuyuki Matsuda, Yasuyuki Suzuki, Naoya Yoshikawa, Tomohisa Yamamoto, Ken Kiyono, Takao Tanahashi, Takuyuki Endo, Kei Fukada, Kunihiko Nomura, Saburo Sakoda, Taishin Nomura
Postural instability is one of the predominant symptoms of Parkinson's disease (PD). Despite its significant impact on the deterioration in quality of life in PD patients, mechanistic causes of the instability have not been clarified. Joint inflexibility at ankle and hip joints might be such a major cause, leading to small variability in the center of pressure (CoP) during quiet stance. However, this conjecture is still controversial. Thus, quantitative characterization of CoP patterns during quiet stance in PD patients remains a matter of research...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28256710/levodopa-response-differs-in-parkinson-s-motor-subtypes-a-task-based-effective-connectivity-study
#12
Brianne Mohl, Brian D Berman, Erika Shelton, Jody Tanabe
Parkinson's disease (PD) is a circuit-level disorder with clinically-determined motor subtypes. Despite evidence suggesting each subtype may have different pathophysiology, few neuroimaging studies have examined levodopa-induced differences in neural activation between tremor dominant (TD) and postural instability/gait difficulty (PIGD) subtype patients during a motor task. The goal of this functional MRI (fMRI) study was to examine task-induced activation and connectivity in the cortico-striatal-thalamo-cortical motor circuit in healthy controls, TD patients, and PIGD patients before and after levodopa administration...
March 3, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28251319/short-term-effectiveness-of-vestibular-rehabilitation-in-elderly-patients-with-postural-instability-a-randomized-clinical-trial
#13
Marcos Rossi-Izquierdo, Pilar Gayoso-Diz, Sofía Santos-Pérez, María Del-Río-Valeiras, Ana Faraldo-García, Isabel Vaamonde-Sánchez-Andrade, Antonio Lirola-Delgado, Andrés Soto-Varela
Balance becomes more precarious with age, and even without pathological disorders, the physiological decline in balance that occurs with age is a factor that also favors falls. So the aim of the present study is to assess the short-term effectiveness of three different methods of vestibular rehabilitation, compared to a control group, in improving balance in elderly patients with postural instability. 139 elderly patients with high risk of falls were included and randomized to one of the following study arms: computer dynamic posturography (CDP) training, optokinetic stimulus, exercises at home, or control group...
March 1, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28238850/further-studies-of-the-effects-of-aging-on-arginine-metabolites-in-the-rat-vestibular-nucleus-and-cerebellum
#14
P Liu, N Gupta, Y Jing, N D Collie, H Zhang, P F Smith
Some studies have demonstrated that aging is associated with impaired vestibular reflexes, especially otolithic reflexes, resulting in postural instability. However, the neurochemical basis of these age-related changes is still poorly understood. The l-arginine metabolic system has been implicated in changes in the brain associated with aging. In the current study, we examined the levels of l-arginine and its metabolizing enzymes and downstream metabolites in the vestibular nucleus complex (VNC) and cerebellum (CE) of rats with and without behavioral testing which were young (4months old), middle-aged (12months old) or aged (24months old)...
February 24, 2017: Neuroscience
https://www.readbyqxmd.com/read/28236606/physical-function-differences-between-the-stages-from-normal-cognition-to-moderate-alzheimer-disease
#15
Chisato Fujisawa, Hiroyuki Umegaki, Kazushi Okamoto, Hirotaka Nakashima, Masafumi Kuzuya, Kenji Toba, Takashi Sakurai
OBJECTIVES: We investigated the differences in the physical function test results across stages from normal cognition (NC) to moderate Alzheimer disease (AD) and how risk factors of physical function decline are correlated with the physical function test results. DESIGN: A cross-sectional study of outpatients at the Memory Disorder Outpatient Center of Japan's National Center of Geriatrics and Gerontology. PARTICIPANTS: We enrolled 882 individuals aged ≥65 diagnosed with NC (n = 210), amnestic mild cognitive impairment (aMCI; n = 273), mild AD (n = 181) or moderate AD (n = 197)...
April 1, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28226430/postural-flexibility-during-quiet-standing-in-healthy-elderly-and-patients-with-parkinson-s-disease
#16
Kazuyuki Matsuda, Yasuyuki Suzuki, Naoya Yoshikawa, Tomohisa Yamamoto, Ken Kiyono, Takao Tanahashi, Takuyuki Endo, Kei Fukada, Kunihiko Nomura, Saburo Sakoda, Taishin Nomura, Kazuyuki Matsuda, Yasuyuki Suzuki, Naoya Yoshikawa, Tomohisa Yamamoto, Ken Kiyono, Takao Tanahashi, Takuyuki Endo, Kei Fukada, Kunihiko Nomura, Saburo Sakoda, Taishin Nomura, Kei Fukada, Naoya Yoshikawa, Tomohisa Yamamoto, Takuyuki Endo, Kunihiko Nomura, Taishin Nomura, Kazuyuki Matsuda, Ken Kiyono, Takao Tanahashi, Saburo Sakoda, Yasuyuki Suzuki
Postural instability is one of the predominant symptoms of Parkinson's disease (PD). Despite its significant impact on the deterioration in quality of life in PD patients, mechanistic causes of the instability have not been clarified. Joint inflexibility at ankle and hip joints might be such a major cause, leading to small variability in the center of pressure (CoP) during quiet stance. However, this conjecture is still controversial. Thus, quantitative characterization of CoP patterns during quiet stance in PD patients remains a matter of research...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28222562/impaired-scaling-of-preparatory-postural-responses-to-repeated-balance-perturbations-in-parkinsonian-patients-with-comorbid-white-matter-disease
#17
David Cioncoloni, Lodovica Martelli, Deborah Rosignoli, Riccardo Mazzocchio
BACKGROUND: Postural instability may result from altered sequencing of automatic motor programs for anticipatory postural corrections and/or impaired motor learning in Parkinson Disease (PD) patients. Comorbid white matter disease is a major determinant of axial motor impairment, leading to poorer stability than nigrostriatal dopaminergic denervation per se. OBJECTIVE: To assess differences in anticipatory control of postural stability function between subjects affected by PD with comorbid leukoaraiosis (LPD), idiopathic Parkinson disease (IPD) and elderly health subjects (EHS) as control group...
February 10, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28187890/evaluation-of-a-smartphone-based-assessment-system-in-subjects-with-chronic-ankle-instability
#18
Ya-Lan Chiu, Yi-Ju Tsai, Chueh-Ho Lin, You-Ruei Hou, Wen-Hsu Sung
BACKGROUND: Ankle sprain is the most common sports-related injury, and approximately 80% of patients studied suffered recurrent sprains. These repeated ankle injuries could cause chronic ankle instability, a decrease in sports performance, and a decrease in postural control ability. At the present time, smartphones have become very popular and powerful devices, and smartphone applications (apps) that have been shown to have good validity have been designed to measure human body motion...
February 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28182968/measuring-postural-control-during-mini-squat-posture-in-men-with-early-knee-osteoarthritis
#19
M Petrella, K Gramani-Say, P R M S Serrão, G C Lessi, J A Barela, R P Carvalho, S M Mattiello
Studies have suggested a compromised postural control in individuals with knee osteoarthritis (OA) evidenced by larger and faster displacement of center of pressure (COP). However, quantification of postural control in the mini-squat posture performed by patients with early knee OA and its relation to muscle strength and self-reported symptoms have not been investigated. The main aim of this cross-sectional, observational, controlled study was to determine whether postural control in the mini-squat posture differs between individuals with early knee OA and a control group (CG) and verify the relation among knee extensor torque (KET) and self-reported physical function, stiffness and pain...
February 6, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28150045/epidemiology-of-parkinson-s-disease
#20
REVIEW
Ole-Bjørn Tysnes, Anette Storstein
Parkinson's disease (PD) affects 1-2 per 1000 of the population at any time. PD prevalence is increasing with age and PD affects 1% of the population above 60 years. The main neuropathological finding is α-synuclein-containing Lewy bodies and loss of dopaminergic neurons in the substantia nigra, manifesting as reduced facilitation of voluntary movements. With progression of PD, Lewy body pathology spreads to neocortical and cortical regions. PD is regarded as a movement disorder with three cardinal signs: tremor, rigidity and bradykinesia...
February 1, 2017: Journal of Neural Transmission
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