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https://www.readbyqxmd.com/read/28732090/incidence-predictors-and-severity-of-adverse-events-among-whole-blood-donors
#1
Hamdan Almutairi, Mahmoud Salam, Abdulaziz Alajlan, Faisal Wani, Bushra Al-Shammari, Khaled Al-Surimi
BACKGROUND: Adverse events have been reported post blood donation. Donors might refrain from donating again due to such events which lowers the blood supply in collection centers. AIM: This study measured the incidence, predictors and severity of adverse events among donors of a single whole blood unit at one of the largest donation centers in Saudi Arabia. METHODS: A retrospective cohort was conducted in 2015 to investigate the adverse events immediately post donation...
2017: PloS One
https://www.readbyqxmd.com/read/28728745/early-readmissions-after-acute-myocardial-infarction
#2
Chun Shing Kwok, Chun Wai Wong, Hannah Shufflebotham, Luke Brindley, Tamseel Fatima, Adrian Shufflebotham, Diane Barker, Ashish Pawala, Grant Heatlie, Mamas A Mamas
This study aims to evaluate the rate, predictors, and causes of 30-day readmissions in a single tertiary hospital in the United Kingdom. We conducted a retrospective study of all patients admitted between 2012 and 2014 with a diagnosis of acute myocardial infarction, who were in the Myocardial Infarction National Audit Project register. Data on patient demographics, comorbidities, care received, and in-hospital mortality were collected. Rates of 30-day readmission and causes of readmission were evaluated. Univariate and multiple logistic regressions were used to identify predictors of all-cause, cardiac, and noncardiac readmission...
June 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28719901/patient-related-benefits-for-adults-with-cochlear-implantation-a-multicultural-longitudinal-observational-study
#3
Thomas Lenarz, Lida Muller, Hanna Czerniejewska-Wolska, Hector Vallés Varela, César Orús Dotú, Marcin Durko, Alicia Huarte Irujo, Bartosz Piszczatowski, Marek Zadrożniak, Colin Irwin, Petra L Graham, Josie Wyss
OBJECTIVES: To assess subjectively perceived, real-world benefits longitudinally for unilateral cochlear implant (CI) recipients in a multinational population treated routinely. To identify possible predictors of self-reported benefits. DESIGN: This was a prospective, multicenter, repeated-measures study. Self-assessment of performance at preimplantation and postimplantation at 1, 2, and 3 years using standardized, validated, local language versions of the Speech, Spatial, and Qualities of Hearing Scale (SSQ), and the Health Utilities Index Mark 3 (HUI3) was performed...
July 19, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28718506/felbamate-as-an-add-on-therapy-for-refractory-partial-epilepsy
#4
REVIEW
Li Li Shi, JianCheng Dong, HengJian Ni, JinSong Geng, Taixiang Wu
BACKGROUND: This review is an update of a previously published review in the Cochrane Database of Systematic Reviews (Issue 7, 2014) on 'Felbamate as an add-on therapy for refractory epilepsy'. Epilepsy is a chronic and disabling neurologic disorder, affecting approximately 1% of the population. Up to 30% of people with epilepsy have seizures that are resistant to currently available drugs. Felbamate is one of the second-generation antiepileptic drugs and we have assessed its effects as an add-on therapy to standard drugs in this review...
July 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28718303/benign-paroxysmal-positional-vertigo-management-and-its-impact-on-falls
#5
Kiran Jumani, Jason Powell
INTRODUCTION: Benign paroxysmal positional vertigo (BPPV) is the most common cause of dizziness in the elderly. This has been identified as a risk factor in falls. Falls are the leading cause of disability and the leading cause of death from injury among people over 75 in the UK. METHODS: We assessed the effect of BPPV treatment on falls in an elderly population by retrospectively reviewing one unit's experience of BPPV management over an 8-year period from June 2008 to June 2016...
August 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28713084/evalution-of-the-effectiveness-of-multimodal-approach-to-the-management-of-cervical-vertigo
#6
Olexandr A Jaroshevskyi, Oleksandr S Payenok, Anna V Logvinenko
INTRODUCTION: Vertigo is one of the most common complaints among patients consulting neurologists and general practitioners - family medicine. A special form of dizziness is cervical vertigo. However, the presence of chronic vertigo and imbalance in this group of patients makes it possible to include the treatment of vestibular rehabilitation in the program. AIM: Evalution of the effectiveness of multimodal approach to the management of cervical vertigo. MATERIAL AND METHODS: 109 patients aged from 18 to 45 with vertigo together with myofascial pain syndrome of neck and shoulder area were examined...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28708707/lightheadedness-after-concussion-not-all-dizziness-is-vertigo
#7
Geoffrey L Heyer, Julie A Young, Anastasia N Fischer
OBJECTIVE: To characterize the presence and degree of postconcussion lightheadedness in relation to postconcussion vertigo and dizziness, and to determine whether lightheadedness influences overall symptom duration. DESIGN: Prospective, cohort design. SETTING: Nationwide Children's Hospital, Sports Concussion Clinic. PARTICIPANTS: Five hundred ten patients (9-19 years of age) within 30 days of concussion injury. MAIN OUTCOME MEASURES: Patient ratings (scale 0-6) of multiple postconcussion symptoms including lightheadedness, vertigo, and dizziness, reported from the day of clinic evaluation and recalled from the day of concussion...
July 11, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28706175/-characteristics-and-risk-factors-for-falls-in-tertiary-hospital-inpatients
#8
Eun Ju Choi, Young Shin Lee, Eun Jung Yang, Ji Hui Kim, Yeon Hee Kim, Hyeoun Ae Park
PURPOSE: The aim of this study was to explore characteristics of and risk factors for accidental inpatient falls. METHODS: Participants were classified as fallers or non-fallers based on the fall history of inpatients in a tertiary hospital in Seoul between June 2014 and May 2015. Data on falls were obtained from the fall report forms and data on risk factors were obtained from the electronic nursing records. Characteristics of fallers and non-fallers were analyzed using descriptive statistics...
June 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28699789/real-world-effectiveness-of-daily-teriparatide-in-japanese-patients-with-osteoporosis-at-high-risk-for-fracture-final-results-from-the-24-month-japan-fracture-observational-study-jfos
#9
Satoshi Soen, Saeko Fujiwara, Ryoichi Takayanagi, Kenta Kajimoto, Mika Tsujimoto, Shuichi Kimura, Masayo Sato, John H Krege, Hiroyuki Enomoto
OBJECTIVE: The Japan Fracture Observational Study (JFOS), a prospective observational study, investigated the real-world effectiveness of daily teriparatide to reduce clinical fracture risk in osteoporotic patients. METHODS: In routine clinical practice, Japanese patients initiated on teriparatide 20 μg/day by subcutaneous injection were enrolled. The primary endpoint was the rate of clinical fractures at 6-month intervals over 24 months. Bone mineral density (BMD), procollagen type 1 aminoterminal propeptide (P1NP), back pain, and health-related quality of life (HRQoL) information was collected...
July 12, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28690706/planning-health-services-for-seniors-can-we-use-patient-s-own-perception
#10
Sabrina Figueiredo, Alicia Rosenzveig, Jose A Morais, Nancy E Mayo
OBJECTIVES: The objectives of this study were to identify needs and to estimate whether self-reported health can be used as an indicator of service needs among seniors. METHODS: This was a cross-sectional survey. Age- and sex-adjusted logistic regression was used to estimate the link between functional status indicators and fair or poor self-reported health. Forward stepwise logistic regression was performed to identify the strongest contributors of poor health...
June 2017: Canadian Geriatrics Journal: CGJ
https://www.readbyqxmd.com/read/28690312/wolff-parkinson-white-syndrome-with-ventricular-hypertrophy-in-a-brazilian-family
#11
Lenises de Paula van der Steld, Oscar Campuzano, Alexandra Pérez-Serra, Mabel Moura de Barros Zamorano, Selma Sousa Matos, Ramon Brugada
BACKGROUND PRKAG2 syndrome diagnosis is already well-defined as Wolff-Parkinson-White syndrome (WPW), ventricular hypertrophy (VH) due to glycogen accumulation, and conduction system disease (CSD). Because of its rarity, there is a lack of literature focused on the treatment. The present study aimed to describe appropriate strategies for the treatment of affected family members with PRKAG2 syndrome with a long follow-up period. CASE REPORT We studied 60 selected individuals from 84 family members (32 males, 53...
July 10, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28689960/scorpion-stings-in-jordan-an-update
#12
Zuhair S Amr, Renad Al Zou'bi, Nour Abdo, Rihan Bani Hani
OBJECTIVE: Scorpionism is an endemic public health problem in Jordan encountered by health providers in all parts of the country. This study updates epidemiological data on scorpion sting encounters in Jordan. METHODS: Data on scorpion sting encounters were obtained from government and military hospitals around the country, and the National Drug and Poison Information Center (NDPIC). P values and 95% confidence intervals (CIs) were calculated using SPSS Professional Statistics Package version 22 (IBM Corp...
July 6, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28687453/cerebellar-stroke-presenting-with-isolated-dizziness-brain-mri-in-136-patients
#13
Michael D Perloff, Nimesh S Patel, Carlos S Kase, Anuja U Oza, Barbara Voetsch, Jose R Romero
OBJECTIVE: To evaluate occurrence of cerebellar stroke in Emergency Department (ED) presentations of isolated dizziness (dizziness with a normal exam and negative neurological review of systems). METHODS: A 5-year retrospective study of ED patients presenting with a chief complaint of "dizziness or vertigo", without other symptoms or signs in narrative history or on exam to suggest a central nervous system lesion, and work-up included a brain MRI within 48h. Patients with symptoms commonly peripheral in etiology (nystagmus, tinnitus, gait instability, etc...
June 22, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28681630/residual-dizziness-after-successful-treatment-of-idiopathic-benign-paroxysmal-positional-vertigo-originates-from-persistent-utricular-dysfunction
#14
Toru Seo, Ko Shiraishi, Takaaki Kobayashi, Kitano Mutsukazu, Takeshi Fujita, Kazuya Saito, Hiroyasu Watanabe, Katsumi Doi
OBJECTIVE: We used ocular vestibular evoked myogenic potentials to investigate the relationship between residual dizziness and utricular function following the canalith repositioning procedure for benign paroxysmal positional vertigo. METHODS: Ocular vestibular evoked myogenic potentials were measured in 44 patients (40 included in analyses, four excluded) with successful results from the canalith repositioning procedure. The patients were examined before treatment and again one week after treatment...
July 6, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28680170/pharmacokinetic-interactions-between-valproic-acid-and-lorazepam-pivotal-study-a-review-of-site-specific-practices
#15
Joane Y Tang, Tony K L Kiang, Mary H H Ensom
BACKGROUND: Coadministration of lorazepam and valproic acid is identified by tertiary references as causing a major drug interaction that requires therapy modification and dosage adjustments. The proposed mechanism involves inhibition of lorazepam glucuronidation via direct inhibition of uridine 5'-diphosphate-glucuronosyltransferase enzymes by valproic acid. However, the clinical significance of this interaction is unclear. OBJECTIVES: To identify site-specific practices and assess clinical responses to the interaction between valproic acid and lorazepam...
May 2017: Canadian Journal of Hospital Pharmacy
https://www.readbyqxmd.com/read/28678941/-analysis-of-prevalence-of-self-reported-hearing-loss-and-associated-factors-primary-versus-proxy-informant
#16
André Luis Alves de Quevedo, Vanessa Bielefeldt Leotti, Bárbara Niegia Garcia de Goulart
The objective was to evaluate differences between prevalence rates for self-reported hearing loss and associated factors, obtained from responses by primary and proxy informants in a Population-Based Study on Human Communication Disorders (DCH-POP in Portuguese). This was a study on epidemiological methods using data from a cross-sectional household survey with a sample of 1,253 individuals from Southern Brazil. To verify differences between prevalence rates comparing primary informants and proxy informants, we used the chi-square or Fisher's exact test for categorical variables and Mann-Whitney for continuous variables...
July 3, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28673380/possible-adverse-effects-of-the-quadrivalent-human-papillomavirus-vaccine-in-the-region-of-southern-denmark-a-retrospective-descriptive-cohort-study
#17
Cecilie Cramon, Christina Lindegaard Poulsen, Ulla Birgitte Hartling, Inge Kristine Holden, Isik Somuncu Johansen
INTRODUCTION: Since the introduction of the quadrivalent human papillomavirus vaccine, young girls and women have reported a broad range of symptoms. These have been described as possible adverse effects of the vaccine. In this study, we describe demographic characteristics, symptomatology, clinical and laboratory test results in patients referred with suspected adverse effects in the Region of Southern Denmark. METHODS: We conducted a retrospective, descriptive study...
July 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28671151/a-profile-of-adverse-effects-of-antihypertensive-medicines-in-a-tertiary-care-clinic-in-nigeria
#18
Abimbola O Olowofela, Ambrose O Isah
BACKGROUND: There has been a dearth of comprehensive data on the profile of adverse reactions to antihypertensive medicines in the Nigerian setting despite increased use. OBJECTIVE: This study was aimed to characterize the adverse reactions experienced in the homogenously black African population. METHODS: The study was carried out at the University of Benin Teaching Hospital, Benin City, Nigeria, in consenting eligible hypertensive patients ≥18 years...
July 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/28670275/results-of-an-interdisciplinary-day-care-approach-for-chronic-tinnitus-treatment-a-prospective-study-introducing-the-jena-interdisciplinary-treatment-for-tinnitus
#19
Daniela Ivansic, Christian Dobel, Gerd F Volk, Daniel Reinhardt, Boris Müller, Ulrich C Smolenski, Orlando Guntinas-Lichius
Objective: Considering the heterogeneity of the symptoms shown by patients suffering from chronic tinnitus, there are surprisingly few interdisciplinary treatments available, and mostly available only for inpatients. In order to provide an interdisciplinary treatment, we developed a day care concept in which each patient was treated by an ENT doctor, a cognitive behavioral therapist, a specialist for medical rehabilitation and an audiologist (Jena Interdisciplinary Treatment for Tinnitus, JITT). The aim of this study was to observe the changes of tinnitus related distress due to interdisciplinary day care treatment and to determine which factors mediate this change...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28669509/out-of-body-experience-in-vestibular-disorders-a-prospective-study-of-210-patients-with-dizziness
#20
Christophe Lopez, Maya Elzière
Out-of-body experiences (OBEs) are states during which people experience their centre of awareness as located outside of their physical body, along with the sensation of seeing the environment from an elevated viewpoint. OBE is encountered in epilepsy, migraine and depersonalization, and it is not an uncommon experience in the general population. Current neuroscientific models of bodily self-consciousness consider that OBE are related to a failure to integrate visual, somatosensory and vestibular signals. These models have highlighted the importance of visual-vestibular mismatch in OBE...
June 8, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
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